| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Brian A Gordon, Tyler Blazey, Yi Su, Anne M Fagan, David M Holtzman, John C Morris, Tammie L S Benzinge. Longitudinal β-Amyloid Deposition and Hippocampal Volume in Preclinical Alzheimer Disease and Suspected Non-Alzheimer Disease Pathophysiology. JAMA neurology. vol 73. issue 10. 2017-05-29. PMID:27548756. |
longitudinal β-amyloid deposition and hippocampal volume in preclinical alzheimer disease and suspected non-alzheimer disease pathophysiology. |
2017-05-29 |
2023-08-13 |
Not clear |
| Sandro Alves, Guillaume Churlaud, Mickael Audrain, Kristin Michaelsen-Preusse, Romain Fol, Benoit Souchet, Jérôme Braudeau, Martin Korte, David Klatzmann, Nathalie Cartie. Interleukin-2 improves amyloid pathology, synaptic failure and memory in Alzheimer's disease mice. Brain : a journal of neurology. vol 140. issue 3. 2017-05-29. PMID:28003243. |
interleukin-2 (il-2)-deficient mice have cytoarchitectural hippocampal modifications and impaired learning and memory ability reminiscent of alzheimer's disease. |
2017-05-29 |
2023-08-13 |
mouse |
| Sandro Alves, Guillaume Churlaud, Mickael Audrain, Kristin Michaelsen-Preusse, Romain Fol, Benoit Souchet, Jérôme Braudeau, Martin Korte, David Klatzmann, Nathalie Cartie. Interleukin-2 improves amyloid pathology, synaptic failure and memory in Alzheimer's disease mice. Brain : a journal of neurology. vol 140. issue 3. 2017-05-29. PMID:28003243. |
therefore, we investigated il-2 levels in hippocampal biopsies of patients with alzheimer's disease relative to age-matched control individuals. |
2017-05-29 |
2023-08-13 |
mouse |
| Sandro Alves, Guillaume Churlaud, Mickael Audrain, Kristin Michaelsen-Preusse, Romain Fol, Benoit Souchet, Jérôme Braudeau, Martin Korte, David Klatzmann, Nathalie Cartie. Interleukin-2 improves amyloid pathology, synaptic failure and memory in Alzheimer's disease mice. Brain : a journal of neurology. vol 140. issue 3. 2017-05-29. PMID:28003243. |
we first found decreased il-2 levels in hippocampal biopsies of patients with alzheimer's disease. |
2017-05-29 |
2023-08-13 |
mouse |
| Patricia A Boyle, Jingyun Yang, Lei Yu, Sue E Leurgans, Ana W Capuano, Julie A Schneider, Robert S Wilson, David A Bennet. Varied effects of age-related neuropathologies on the trajectory of late life cognitive decline. Brain : a journal of neurology. vol 140. issue 3. 2017-05-29. PMID:28082297. |
alzheimer's disease pathology, macroscopic infarcts, lewy bodies, tdp-43 pathology, and hippocampal sclerosis were associated with progressive cognitive decline, with their deleterious effects increasing over time. |
2017-05-29 |
2023-08-13 |
human |
| Luca Passamonti, Patricia Vázquez Rodríguez, Young T Hong, Kieren S J Allinson, David Williamson, Robin J Borchert, Saber Sami, Thomas E Cope, W Richard Bevan-Jones, P Simon Jones, Robert Arnold, Ajenthan Surendranathan, Elijah Mak, Li Su, Tim D Fryer, Franklin I Aigbirhio, John T O'Brien, James B Row. 18F-AV-1451 positron emission tomography in Alzheimer's disease and progressive supranuclear palsy. Brain : a journal of neurology. vol 140. issue 3. 2017-05-29. PMID:28122879. |
more specifically, 18f-av-1451 binding was significantly increased in patients with alzheimer's disease, relative to patients with progressive supranuclear palsy and with control subjects, in the hippocampus and in occipital, parietal, temporal, and frontal cortices (t's > 2.2, p's < 0.04). |
2017-05-29 |
2023-08-13 |
human |
| Huimin Zhou, Rui Zhang, Kang Lu, Wenjun Yu, Bing Xie, Dongsheng Cui, Lei Jiang, Qingfu Zhang, Shunjiang X. Deregulation of miRNA-181c potentially contributes to the pathogenesis of AD by targeting collapsin response mediator protein 2 in mice. Journal of the neurological sciences. vol 367. 2017-05-17. PMID:27423553. |
taken together, these findings suggested that crmp2 is a target of mir-181c and that the abnormally low expression of mir-181c in the hippocampus of samp8 mice could lead to an increase of the crmp2 protein level in ad mice, which might potentially play a role in the pathogenesis of alzheimer's disease. |
2017-05-17 |
2023-08-13 |
mouse |
| Cátia F Lourenço, Ana Ledo, Rui M Barbosa, João Laranjinh. Neurovascular uncoupling in the triple transgenic model of Alzheimer's disease: Impaired cerebral blood flow response to neuronal-derived nitric oxide signaling. Experimental neurology. vol 291. 2017-05-16. PMID:28161255. |
in this work, we aimed at investigating whether and to what extent neuronal-derived no signaling and related neurovascular coupling are impaired along aging in the hippocampus of the triple transgenic mouse model of alzheimer's disease (3xtg-ad). |
2017-05-16 |
2023-08-13 |
mouse |
| Kejal Kantarci, Timothy Lesnick, Tanis J Ferman, Scott A Przybelski, Bradley F Boeve, Glenn E Smith, Walter K Kremers, David S Knopman, Clifford R Jack, Ronald C Peterse. Hippocampal volumes predict risk of dementia with Lewy bodies in mild cognitive impairment. Neurology. vol 87. issue 22. 2017-05-12. PMID:27807186. |
to predict the risk of probable dementia with lewy bodies (dlb) competing with alzheimer disease (ad) dementia by hippocampal volume (hv) in patients with mild cognitive impairment (mci) with impairments in amnestic or nonamnestic cognitive domains. |
2017-05-12 |
2023-08-13 |
Not clear |
| John P Aggleton, Agathe Pralus, Andrew J D Nelson, Michael Hornberge. Thalamic pathology and memory loss in early Alzheimer's disease: moving the focus from the medial temporal lobe to Papez circuit. Brain : a journal of neurology. vol 139. issue Pt 7. 2017-05-10. PMID:27190025. |
consequently, research into the causes of memory loss in alzheimer's disease continues to centre on hippocampal dysfunction and how disease-modifying therapies in this region can potentially alleviate memory symptomology. |
2017-05-10 |
2023-08-13 |
Not clear |
| Jin Gyu Choi, Namkwon Kim, Eugene Huh, Hwan Lee, Myeong Hwan Oh, Jong Dae Park, Mi Kyung Pyo, Myung Sook O. White Ginseng Protects Mouse Hippocampal Cells Against Amyloid-Beta Oligomer Toxicity. Phytotherapy research : PTR. vol 31. issue 3. 2017-05-09. PMID:28112442. |
these results suggest that wge reverses memory impairment in alzheimer's disease by attenuating neuronal damage and neuroinflammation in the aβo-injected mouse hippocampus. |
2017-05-09 |
2023-08-13 |
mouse |
| Marta Nesteruk, Tomasz Nesteruk, Maria Styczyńska, Monika Mandecka, Anna Barczak, Maria Barcikowsk. Combined use of biochemical and volumetric biomarkers to assess the risk of conversion of mild cognitive impairment to Alzheimer's disease. Folia neuropathologica. vol 54. issue 4. 2017-05-09. PMID:28139818. |
the aim of our study was to evaluate the usefulness of several biomarkers in predicting the conversion of mild cognitive impairment (mci) to alzheimer's disease (ad): β-amyloid and tau proteins in cerebrospinal fluid and the volumetric evaluation of brain structures including the hippocampus in magnetic resonance imaging (mri). |
2017-05-09 |
2023-08-13 |
Not clear |
| François-Laurent De Winter, Louise Emsell, Filip Bouckaert, Lene Claes, Saurabh Jain, Gill Farrar, Thibo Billiet, Stephan Evers, Jan Van den Stock, Pascal Sienaert, Jasmien Obbels, Stefan Sunaert, Katarzyna Adamczuk, Rik Vandenberghe, Koen Van Laere, Mathieu Vandenbulck. No Association of Lower Hippocampal Volume With Alzheimer's Disease Pathology in Late-Life Depression. The American journal of psychiatry. vol 174. issue 3. 2017-05-01. PMID:27539488. |
no association of lower hippocampal volume with alzheimer's disease pathology in late-life depression. |
2017-05-01 |
2023-08-13 |
Not clear |
| François-Laurent De Winter, Louise Emsell, Filip Bouckaert, Lene Claes, Saurabh Jain, Gill Farrar, Thibo Billiet, Stephan Evers, Jan Van den Stock, Pascal Sienaert, Jasmien Obbels, Stefan Sunaert, Katarzyna Adamczuk, Rik Vandenberghe, Koen Van Laere, Mathieu Vandenbulck. No Association of Lower Hippocampal Volume With Alzheimer's Disease Pathology in Late-Life Depression. The American journal of psychiatry. vol 174. issue 3. 2017-05-01. PMID:27539488. |
the purpose of this prospective study was to examine whether lower hippocampal volume in late-life depression is associated with alzheimer's disease pathology. |
2017-05-01 |
2023-08-13 |
Not clear |
| Perla Moreno-Castilla, Rodrigo Pérez-Ortega, Valeria Violante-Soria, Israela Balderas, Federico Bermúdez-Ratton. Hippocampal release of dopamine and norepinephrine encodes novel contextual information. Hippocampus. vol 27. issue 5. 2017-04-25. PMID:28176408. |
the significance of catecholaminergic function may be extended to the clinical field as it has been reported that innervation of hippocampus by the noradrenergic and dopaminergic system is reduced and atrophied in aging and alzheimer's disease brain. |
2017-04-25 |
2023-08-13 |
mouse |
| Alessia Giuliano, Graziella Donatelli, Mirco Cosottini, Michela Tosetti, Alessandra Retico, Maria Evelina Fantacc. Hippocampal subfields at ultra high field MRI: An overview of segmentation and measurement methods. Hippocampus. vol 27. issue 5. 2017-04-25. PMID:28188659. |
studying the morphometry of the hippocampus is crucial in neuroimaging research because changes in volume and thickness of hippocampal subregions may be relevant in the early assessment of pathological cognitive decline and alzheimer's disease (ad). |
2017-04-25 |
2023-08-13 |
Not clear |
| Szabolcs Kér. How assistive technology changes the brain: the critical role of hippocampal-striatal interactions during cognitive training. Studies in health technology and informatics. vol 217. 2017-04-24. PMID:26294535. |
in this study, we show that extensive training with a platformer game simulating navigation and real-life spatial abilities, patients with alzheimer's disease and amnestic mild cognitive impairmant exhibit an increased volume of the caudate nucleus in contrast to healthy individuals who display increased hippocampal volumes. |
2017-04-24 |
2023-08-13 |
Not clear |
| Sravan Gopalkrishnashetty Sreenivasmurthy, Jing-Yi Liu, Ju-Xian Song, Chuan-Bin Yang, Sandeep Malampati, Zi-Ying Wang, Ying-Yu Huang, Min L. Neurogenic Traditional Chinese Medicine as a Promising Strategy for the Treatment of Alzheimer's Disease. International journal of molecular sciences. vol 18. issue 2. 2017-04-24. PMID:28134846. |
attenuation of neurogenesis in the brain is one of the primary causes of dementia in alzheimer's disease (ad), and, conversely, modulating the process of hippocampal neurogenesis benefit patients with ad. |
2017-04-24 |
2023-08-13 |
Not clear |
| Keith A Josephs, Melissa E Murray, Nirubol Tosakulwong, Jennifer L Whitwell, David S Knopman, Mary M Machulda, Stephen D Weigand, Bradley F Boeve, Kejal Kantarci, Leonard Petrucelli, Val J Lowe, Clifford R Jack, Ronald C Petersen, Joseph E Parisi, Dennis W Dickso. Tau aggregation influences cognition and hippocampal atrophy in the absence of beta-amyloid: a clinico-imaging-pathological study of primary age-related tauopathy (PART). Acta neuropathologica. vol 133. issue 5. 2017-04-20. PMID:28160067. |
the relatively low frequencies of apoe4, tdp-43, lewy bodies, and hippocampal sclerosis, and the rarity and morphology of tdp-43 lesions are noted contrasts to what is typically observed in alzheimer's disease of the old. |
2017-04-20 |
2023-08-13 |
Not clear |
| Erin E Sundermann, Anat Biegon, Leah H Rubin, Richard B Lipton, Wenzhu Mowrey, Susan Landau, Pauline M Mak. Better verbal memory in women than men in MCI despite similar levels of hippocampal atrophy. Neurology. vol 86. issue 15. 2017-04-19. PMID:26984945. |
to examine sex differences in the relationship between clinical symptoms related to alzheimer disease (ad) (verbal memory deficits) and neurodegeneration (hippocampal volume/intracranial volume ratio [hpvr]) across ad stages. |
2017-04-19 |
2023-08-13 |
Not clear |