| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mi-Hyun Choi, Hyung-Sik Kim, Seon-Young Gim, Woo-Ram Kim, Kyung-Ryul Mun, Gye-Rae Tack, Bongsoo Lee, Young Chil Choi, Hyun-Jun Kim, Seung Hwa Hong, Dae-Woon Lim, Soon-Cheol Chun. Differences in cognitive ability and hippocampal volume between Alzheimer's disease, amnestic mild cognitive impairment, and healthy control groups, and their correlation. Neuroscience letters. vol 620. 2017-07-24. PMID:27019036. |
the study investigated differences in cognitive ability and hippocampal volume between groups of patients with alzheimer's disease (ad) and amnestic mild cognitive impairment (amci), and healthy control (hc) subjects, and explored the relationship between cognitive ability and hippocampal volume. |
2017-07-24 |
2023-08-13 |
human |
| Ting Yang, Shaomin Li, Huixin Xu, Dominic M Walsh, Dennis J Selko. Large Soluble Oligomers of Amyloid β-Protein from Alzheimer Brain Are Far Less Neuroactive Than the Smaller Oligomers to Which They Dissociate. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 1. 2017-07-24. PMID:28053038. |
soluble oligomers of amyloid β-protein (oaβ) isolated from the brains of alzheimer's disease (ad) patients have been shown experimentally (in the absence of amyloid plaques) to impair hippocampal synaptic plasticity, decrease synapses, induce tau hyperphosphorylation and neuritic dystrophy, activate microglial inflammation, and impair memory in normal adult rodents. |
2017-07-24 |
2023-08-13 |
mouse |
| Mengqian Li, Yefeng Yuan, Bo Hu, Lei W. Study on Lentivirus-Mediated ABCA7 Improves Neurocognitive Function and Related Mechanisms in the C57BL/6 Mouse Model of Alzheimer's Disease. Journal of molecular neuroscience : MN. vol 61. issue 4. 2017-07-24. PMID:28124230. |
atp-binding cassette transporter a7 (abca7) is expressed in the hippocampus and cortex of the brain and was confirmed to be involved in the development of alzheimer's disease (ad). |
2017-07-24 |
2023-08-13 |
mouse |
| Robert J Pawlosky, Martin F Kemper, Yoshihero Kashiwaya, Michael Todd King, Mark P Mattson, Richard L Veec. Effects of a dietary ketone ester on hippocampal glycolytic and tricarboxylic acid cycle intermediates and amino acids in a 3xTgAD mouse model of Alzheimer's disease. Journal of neurochemistry. vol 141. issue 2. 2017-07-13. PMID:28099989. |
effects of a dietary ketone ester on hippocampal glycolytic and tricarboxylic acid cycle intermediates and amino acids in a 3xtgad mouse model of alzheimer's disease. |
2017-07-13 |
2023-08-13 |
mouse |
| Zi-Xuan Wang, Hui-Fu Wang, Lin Tan, Fu-Rong Sun, Meng-Shan Tan, Chen-Chen Tan, Teng Jiang, Lan Tan, Jin-Tai Y. HLA-A2 Alleles Mediate Alzheimer's Disease by Altering Hippocampal Volume. Molecular neurobiology. vol 54. issue 4. 2017-06-30. PMID:26979752. |
hla-a2 alleles mediate alzheimer's disease by altering hippocampal volume. |
2017-06-30 |
2023-08-13 |
Not clear |
| Shunichiro Shinagawa, Nobuyuki Kobayashi, Tomoyuki Nagata, Akira Kusaka, Hisashi Yamada, Kazuhiro Kondo, Kazuhiko Nakayam. DNA methylation in the NCAPH2/LMF2 promoter region is associated with hippocampal atrophy in Alzheimer's disease and amnesic mild cognitive impairment patients. Neuroscience letters. vol 629. 2017-06-29. PMID:27356276. |
dna methylation in the ncaph2/lmf2 promoter region is associated with hippocampal atrophy in alzheimer's disease and amnesic mild cognitive impairment patients. |
2017-06-29 |
2023-08-13 |
human |
| Shunichiro Shinagawa, Nobuyuki Kobayashi, Tomoyuki Nagata, Akira Kusaka, Hisashi Yamada, Kazuhiro Kondo, Kazuhiko Nakayam. DNA methylation in the NCAPH2/LMF2 promoter region is associated with hippocampal atrophy in Alzheimer's disease and amnesic mild cognitive impairment patients. Neuroscience letters. vol 629. 2017-06-29. PMID:27356276. |
degrees of hippocampal atrophy and total brain atrophy were measured by vsrad (voxel-based specific regional analysis system for alzheimer's disease). |
2017-06-29 |
2023-08-13 |
human |
| Adrián G Sandoval-Hernández, Alejandro Restrepo, Gloria P Cardona-Gómez, Gonzalo Arboled. LXR activation protects hippocampal microvasculature in very old triple transgenic mouse model of Alzheimer's disease. Neuroscience letters. vol 621. 2017-06-21. PMID:27057732. |
lxr activation protects hippocampal microvasculature in very old triple transgenic mouse model of alzheimer's disease. |
2017-06-21 |
2023-08-13 |
mouse |
| Christopher D Morrone, Lynsie A M Thomason, Mary E Brown, Isabelle Aubert, JoAnne McLauri. Effects of Neurotrophic Support and Amyloid-Targeted Combined Therapy on Adult Hippocampal Neurogenesis in a Transgenic Model of Alzheimer's Disease. PloS one. vol 11. issue 10. 2017-06-20. PMID:27768761. |
effects of neurotrophic support and amyloid-targeted combined therapy on adult hippocampal neurogenesis in a transgenic model of alzheimer's disease. |
2017-06-20 |
2023-08-13 |
mouse |
| Kazuyuki Fukushima, Yoshikuni Tabata, Yoichi Imaizumi, Naohiro Kohmura, Michiko Sugawara, Kohei Sawada, Kazuto Yamazaki, Masashi It. Characterization of Human Hippocampal Neural Stem/Progenitor Cells and Their Application to Physiologically Relevant Assays for Multiple Ionotropic Glutamate Receptors. Journal of biomolecular screening. vol 19. issue 8. 2017-06-19. PMID:24980597. |
the hippocampus is an important brain region that is involved in neurological disorders such as alzheimer disease, schizophrenia, and epilepsy. |
2017-06-19 |
2023-08-13 |
human |
| Mickael Dinomais, Sebastien Celle, Guillaume T Duval, Frederic Roche, Samir Henni, Robert Bartha, Olivier Beauchet, Cedric Annweile. Anatomic Correlation of the Mini-Mental State Examination: A Voxel-Based Morphometric Study in Older Adults. PloS one. vol 11. issue 10. 2017-06-13. PMID:27741236. |
we found correlations between the mmse score and specific cortical regions of the limbic system including the hippocampus, amygdala, cingulate gyrus, and parahippocampal gyrus, independently of the diagnostic category (i.e., mild cognitive impairment or alzheimer disease or controls). |
2017-06-13 |
2023-08-13 |
human |
| Duttagupta Subhadeep, B N Srikumar, B S Shankaranarayana Rao, Bindu M Kutt. Exposure to short photoperiod regime reduces ventral subicular lesion-induced anxiety-like behavior in Wistar rats. Physiology & behavior. vol 170. 2017-06-13. PMID:28017681. |
neurodegeneration of hippocampal structures is implicated in alzheimer's disease (ad). |
2017-06-13 |
2023-08-13 |
rat |
| Lakshini H S Mendis, Angus C Grey, Richard L M Faull, Maurice A Curti. Hippocampal lipid differences in Alzheimer's disease: a human brain study using matrix-assisted laser desorption/ionization-imaging mass spectrometry. Brain and behavior. vol 6. issue 10. 2017-06-12. PMID:27781133. |
hippocampal lipid differences in alzheimer's disease: a human brain study using matrix-assisted laser desorption/ionization-imaging mass spectrometry. |
2017-06-12 |
2023-08-13 |
human |
| Gabrielle F Ruggiero, Jeannette Y Wic. Olfaction: New Understandings, Diagnostic Applications. The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists. vol 31. issue 11. 2017-06-06. PMID:28107119. |
it's also an initial symptom of alzheimer's dementia (ad); the amyloid plaques and tangles characterizing ad invade the olfactory bulb and hippocampus early in its course, hampering odor identification. |
2017-06-06 |
2023-08-13 |
Not clear |
| Rui Zheng, Zhong-Hao Zhang, Chen Chen, Yao Chen, Shi-Zheng Jia, Qiong Liu, Jia-Zuan Ni, Guo-Li Son. Selenomethionine promoted hippocampal neurogenesis via the PI3K-Akt-GSK3β-Wnt pathway in a mouse model of Alzheimer's disease. Biochemical and biophysical research communications. vol 485. issue 1. 2017-06-06. PMID:28109879. |
selenomethionine promoted hippocampal neurogenesis via the pi3k-akt-gsk3β-wnt pathway in a mouse model of alzheimer's disease. |
2017-06-06 |
2023-08-13 |
mouse |
| Srinivas Ayyadevara, Meenakshisundaram Balasubramaniam, Paul A Parcon, Steven W Barger, W Sue T Griffin, Ramani Alla, Alan J Tackett, Samuel G Mackintosh, Emanuel Petricoin, Weidong Zhou, Robert J Shmookler Rei. Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls. Aging cell. vol 15. issue 5. 2017-06-05. PMID:27448508. |
proteins that mediate protein aggregation and cytotoxicity distinguish alzheimer's hippocampus from normal controls. |
2017-06-05 |
2023-08-13 |
human |
| Srinivas Ayyadevara, Meenakshisundaram Balasubramaniam, Paul A Parcon, Steven W Barger, W Sue T Griffin, Ramani Alla, Alan J Tackett, Samuel G Mackintosh, Emanuel Petricoin, Weidong Zhou, Robert J Shmookler Rei. Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls. Aging cell. vol 15. issue 5. 2017-06-05. PMID:27448508. |
compact hippocampal aggregates were purified from alzheimer's and control-subject pools using magnetic-bead immunoaffinity pulldowns. |
2017-06-05 |
2023-08-13 |
human |
| Cyril Laurent, Guillaume Dorothée, Stéphane Hunot, Elodie Martin, Yann Monnet, Marie Duchamp, Yuan Dong, François-Pierre Légeron, Antoine Leboucher, Sylvie Burnouf, Emilie Faivre, Kévin Carvalho, Raphaëlle Caillierez, Nadège Zommer, Dominique Demeyer, Nathalie Jouy, Veronique Sazdovitch, Susanna Schraen-Maschke, Cécile Delarasse, Luc Buée, David Blu. Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy. Brain : a journal of neurology. vol 140. issue 1. 2017-06-05. PMID:27818384. |
altogether, these data support an instrumental role of hippocampal t cell infiltration in tau-driven pathophysiology and cognitive impairments in alzheimer's disease and other tauopathies. |
2017-06-05 |
2023-08-13 |
mouse |
| Gamze Balci Camsari, Melissa E Murray, Neill R Graff-Radfor. Case Studies Illustrating Focal Alzheimer's, Fluent Aphasia, Late-Onset Memory Loss, and Rapid Dementia. Neurologic clinics. vol 34. issue 3. 2017-06-01. PMID:27445249. |
these include focal cortical presentations of alzheimer's disease (ad; posterior cortical atrophy and corticobasal syndrome [cbs]), fluent aphasia (semantic dementia and logopenic aphasia), late-onset slowly progressive dementia (hippocampal sclerosis and limbic predominant ad) and rapidly progressive dementia (creutzfeldt-jakob disease and limbic encephalitis). |
2017-06-01 |
2023-08-13 |
Not clear |
| Yan Liu, Yanfeng Xu, Ling Zhang, Lan Huang, Pin Yu, Hua Zhu, Wei Deng, Chuan Qi. Down-Regulated Drebrin Aggravates Cognitive Impairments in a Mouse Model of Alzheimer's Disease. International journal of molecular sciences. vol 18. issue 4. 2017-06-01. PMID:28398234. |
a noticeable decline of this protein has been found in the hippocampus and cortex of patients with alzheimer's disease (ad), yet the relationship between dbn and ad has not been fully understood. |
2017-06-01 |
2023-08-13 |
mouse |