| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jahnavi Suresh, Ing Wei Khor, Prameet Kaur, Hui Li Heng, Federico Torta, Gavin S Dawe, E Shyong Tai, Nicholas S Tolwinsk. Shared signaling pathways in Alzheimer's and metabolic disease may point to new treatment approaches. The FEBS journal. vol 288. issue 12. 2021-07-22. PMID:32853472. |
'a peculiar severe disease process of the cerebral cortex' are the exact words used by a. alzheimer in 1906 to describe a patient's increasingly severe condition of memory loss, changes in personality, and sleep disturbance. |
2021-07-22 |
2023-08-13 |
Not clear |
| Lin Zhu, Zan Wang, Zhanhong Du, Xinyang Qi, Hao Shu, Duan Liu, Fan Su, Qing Ye, Xuemei Liu, Zheng Zhou, Yongqiang Tang, Ru Song, Xiaobin Wang, Li Lin, Shijiang Li, Ying Han, Liping Wang, Zhijun Zhan. Impaired Parahippocampal Gyrus-Orbitofrontal Cortex Circuit Associated with Visuospatial Memory Deficit as a Potential Biomarker and Interventional Approach for Alzheimer Disease. Neuroscience bulletin. vol 36. issue 8. 2021-07-19. PMID:32350798. |
impaired parahippocampal gyrus-orbitofrontal cortex circuit associated with visuospatial memory deficit as a potential biomarker and interventional approach for alzheimer disease. |
2021-07-19 |
2023-08-13 |
mouse |
| Zhi-Hang Zhen, Mo-Ran Guo, He-Ming Li, Ou-Yang Guo, Jun-Li Zhen, Jian Fu, Guo-Jun Ta. Normal and Abnormal Sharp Wave Ripples in the Hippocampal-Entorhinal Cortex System: Implications for Memory Consolidation, Alzheimer's Disease, and Temporal Lobe Epilepsy. Frontiers in aging neuroscience. vol 13. 2021-07-16. PMID:34262446. |
normal and abnormal sharp wave ripples in the hippocampal-entorhinal cortex system: implications for memory consolidation, alzheimer's disease, and temporal lobe epilepsy. |
2021-07-16 |
2023-08-13 |
Not clear |
| Olayemi Joseph Olajide, Marcus E Suvanto, Clifton Andrew Chapma. Molecular mechanisms of neurodegeneration in the entorhinal cortex that underlie its selective vulnerability during the pathogenesis of Alzheimer's disease. Biology open. vol 10. issue 1. 2021-07-15. PMID:33495355. |
molecular mechanisms of neurodegeneration in the entorhinal cortex that underlie its selective vulnerability during the pathogenesis of alzheimer's disease. |
2021-07-15 |
2023-08-13 |
Not clear |
| Yangjie Jia, Xia Wang, Yanyu Chen, Wenying Qiu, Wei Ge, Chao M. Proteomic and Transcriptomic Analyses Reveal Pathological Changes in the Entorhinal Cortex Region that Correlate Well with Dysregulation of Ion Transport in Patients with Alzheimer's Disease. Molecular neurobiology. vol 58. issue 8. 2021-07-15. PMID:33904022. |
proteomic and transcriptomic analyses reveal pathological changes in the entorhinal cortex region that correlate well with dysregulation of ion transport in patients with alzheimer's disease. |
2021-07-15 |
2023-08-13 |
Not clear |
| Qing Xia, XinYu Yang, JiaBin Shi, ZiJie Liu, YaHui Peng, WenJing Wang, BoWen Li, Yu Zhao, JiaYing Xiao, Lei Huang, DaYong Wang, Xu Ga. The Protective A673T Mutation of Amyloid Precursor Protein (APP) in Alzheimer's Disease. Molecular neurobiology. vol 58. issue 8. 2021-07-15. PMID:33914267. |
alzheimer's disease is a progressive neurodegenerative disorder characterized by extracellular amyloid beta peptides and neurofibrillary tangles consisted of intracellular hyperphosphorylated tau in the hippocampus and cerebral cortex. |
2021-07-15 |
2023-08-13 |
Not clear |
| Eva Babusikova, Dusan Dobrota, Anthony J Turner, Natalia N Nalivaev. Effect of Global Brain Ischemia on Amyloid Precursor Protein Metabolism and Expression of Amyloid-Degrading Enzymes in Rat Cortex: Role in Pathogenesis of Alzheimer's Disease. Biochemistry. Biokhimiia. vol 86. issue 6. 2021-07-15. PMID:34225591. |
effect of global brain ischemia on amyloid precursor protein metabolism and expression of amyloid-degrading enzymes in rat cortex: role in pathogenesis of alzheimer's disease. |
2021-07-15 |
2023-08-13 |
rat |
| Haoming Li, Linqing Zou, Jinhong Shi, Xiao Ha. Bioinformatics analysis of differentially expressed genes and identification of an miRNA-mRNA network associated with entorhinal cortex and hippocampus in Alzheimer's disease. Hereditas. vol 158. issue 1. 2021-07-13. PMID:34243818. |
bioinformatics analysis of differentially expressed genes and identification of an mirna-mrna network associated with entorhinal cortex and hippocampus in alzheimer's disease. |
2021-07-13 |
2023-08-13 |
Not clear |
| Haoming Li, Linqing Zou, Jinhong Shi, Xiao Ha. Bioinformatics analysis of differentially expressed genes and identification of an miRNA-mRNA network associated with entorhinal cortex and hippocampus in Alzheimer's disease. Hereditas. vol 158. issue 1. 2021-07-13. PMID:34243818. |
alzheimer's disease (ad) is a fatal neurodegenerative disorder, and the lesions originate in the entorhinal cortex (ec) and hippocampus (hip) at the early stage of ad progression. |
2021-07-13 |
2023-08-13 |
Not clear |
| Huan Cui, Si Su, Yan Cao, Chao Ma, Wenying Qi. The Altered Anatomical Distribution of ACE2 in the Brain With Alzheimer's Disease Pathology. Frontiers in cell and developmental biology. vol 9. 2021-07-13. PMID:34249938. |
in addition, this study demonstrates that the protein level of ace2 was downregulated in the basal nucleus, hippocampus and entorhinal cortex, middle frontal gyrus, visual cortex, and amygdala of the brain with alzheimer's disease (ad) pathology. |
2021-07-13 |
2023-08-13 |
human |
| Margot Juliëtte Overman, Giovanna Zamboni, Christopher Butler, Samrah Ahme. Splenial white matter integrity is associated with memory impairments in posterior cortical atrophy. Brain communications. vol 3. issue 2. 2021-07-05. PMID:34007964. |
posterior cortical atrophy is an atypical form of alzheimer's disease characterized by visuospatial impairments and predominant tissue loss in the posterior parieto-occipital and temporo-occipital cortex. |
2021-07-05 |
2023-08-13 |
Not clear |
| Satvik Kotha, Swapna B, Vithal M Kulkarni, Ramachandra Setty S, Harish Kumar B, Harisha . An in-silico approach: identification of PPAR-γ agonists from seaweeds for the management of Alzheimer's Disease. Journal of biomolecular structure & dynamics. vol 39. issue 6. 2021-07-02. PMID:32216605. |
alzheimer's disease is a complex progressive neurodegenerative disorder characterized by neurofibrillary tangles and senile plaques in various parts of the brain particularly cerebral cortex affecting memory and cognition. |
2021-07-02 |
2023-08-13 |
Not clear |
| M Domínguez-Álvaro, M Montero-Crespo, L Blazquez-Llorca, S Plaza-Alonso, N Cano-Astorga, J DeFelipe, L Alonso-Nanclare. 3D Analysis of the Synaptic Organization in the Entorhinal Cortex in Alzheimer's Disease. eNeuro. vol 8. issue 3. 2021-07-02. PMID:34039651. |
3d analysis of the synaptic organization in the entorhinal cortex in alzheimer's disease. |
2021-07-02 |
2023-08-13 |
human |
| M Domínguez-Álvaro, M Montero-Crespo, L Blazquez-Llorca, S Plaza-Alonso, N Cano-Astorga, J DeFelipe, L Alonso-Nanclare. 3D Analysis of the Synaptic Organization in the Entorhinal Cortex in Alzheimer's Disease. eNeuro. vol 8. issue 3. 2021-07-02. PMID:34039651. |
the entorhinal cortex (ec) is especially vulnerable in the early stages of alzheimer's disease (ad). |
2021-07-02 |
2023-08-13 |
human |
| Hong Wang, Kaushik Kumar Dey, Ping-Chung Chen, Yuxin Li, Mingming Niu, Ji-Hoon Cho, Xusheng Wang, Bing Bai, Yun Jiao, Surendhar Reddy Chepyala, Vahram Haroutunian, Bin Zhang, Thomas G Beach, Junmin Pen. Integrated analysis of ultra-deep proteomes in cortex, cerebrospinal fluid and serum reveals a mitochondrial signature in Alzheimer's disease. Molecular neurodegeneration. vol 15. issue 1. 2021-07-01. PMID:32711556. |
integrated analysis of ultra-deep proteomes in cortex, cerebrospinal fluid and serum reveals a mitochondrial signature in alzheimer's disease. |
2021-07-01 |
2023-08-13 |
human |
| Inès M Bigarré, Bianca A Trombetta, Yan-Jun Guo, Steven E Arnold, Becky C Carlyl. IGF2R circular RNA hsa_circ_0131235 expression in the middle temporal cortex is associated with AD pathology. Brain and behavior. vol 11. issue 4. 2021-06-30. PMID:33704916. |
to identify circular rnas as candidates for differential expression in the middle temporal (mt) cortex in a well-characterized cohort with contrasting alzheimer disease (ad) pathology and cognition. |
2021-06-30 |
2023-08-13 |
Not clear |
| Natsuko Iizuka, Yuri Masaoka, Satomi Kubota, Haruko Sugiyama, Masaki Yoshida, Akira Yoshikawa, Nobuyoshi Koiwa, Motoyasu Honma, Keiko Watanabe, Shotaro Kamijo, Sawa Kamimura, Masahiro Ida, Kenjiro Ono, Masahiko Izumizak. Entorhinal cortex and parahippocampus volume reductions impact olfactory decline in aged subjects. Brain and behavior. vol 11. issue 5. 2021-06-30. PMID:33769719. |
pathological abnormalities first appear in the medial temporal regions including entorhinal cortex and parahippocampus in patients with alzheimer's disease. |
2021-06-30 |
2023-08-13 |
human |
| Rebecca G Smith, Ehsan Pishva, Gemma Shireby, Adam R Smith, Janou A Y Roubroeks, Eilis Hannon, Gregory Wheildon, Diego Mastroeni, Gilles Gasparoni, Matthias Riemenschneider, Armin Giese, Andrew J Sharp, Leonard Schalkwyk, Vahram Haroutunian, Wolfgang Viechtbauer, Daniel L A van den Hove, Michael Weedon, Danielle Brokaw, Paul T Francis, Alan J Thomas, Seth Love, Kevin Morgan, Jörn Walter, Paul D Coleman, David A Bennett, Philip L De Jager, Jonathan Mill, Katie Lunno. A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex. Nature communications. vol 12. issue 1. 2021-06-29. PMID:34112773. |
a meta-analysis of epigenome-wide association studies in alzheimer's disease highlights novel differentially methylated loci across cortex. |
2021-06-29 |
2023-08-13 |
Not clear |
| Rebecca G Smith, Ehsan Pishva, Gemma Shireby, Adam R Smith, Janou A Y Roubroeks, Eilis Hannon, Gregory Wheildon, Diego Mastroeni, Gilles Gasparoni, Matthias Riemenschneider, Armin Giese, Andrew J Sharp, Leonard Schalkwyk, Vahram Haroutunian, Wolfgang Viechtbauer, Daniel L A van den Hove, Michael Weedon, Danielle Brokaw, Paul T Francis, Alan J Thomas, Seth Love, Kevin Morgan, Jörn Walter, Paul D Coleman, David A Bennett, Philip L De Jager, Jonathan Mill, Katie Lunno. A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex. Nature communications. vol 12. issue 1. 2021-06-29. PMID:34112773. |
here, we combine data from six dna methylomic studies of alzheimer's disease (n = 1453 unique individuals) to identify differential methylation associated with braak stage in different brain regions and across cortex. |
2021-06-29 |
2023-08-13 |
Not clear |
| Maira Dos Santos Carneiro Lacerda, Tais Meziara Wilson, Verônica Lourença de Souza Argenta, Érika Garcia de Araújo Pinto, Juliana Targino Silva Almeida E Macêdo, Benito Soto-Blanco, Kelly Moura Keller, Pedro Miguel Ocampos Pedroso, Antônio Carlos Lopes Câmar. Crotalaria spectabilis poisoning in horses fed contaminating oats. Toxicon : official journal of the International Society on Toxinology. vol 197. 2021-06-24. PMID:33852904. |
other findings were alzheimer's type ii astrocytes in the cortex, midbrain, basal nuclei, brainstem and pons; multifocal edema and hemorrhage in the lungs; and degeneration and necrosis of the tubular epithelium of kidneys. |
2021-06-24 |
2023-08-13 |
Not clear |