| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C B Saper, D C Germa. Hypothalamic pathology in Alzheimer's disease. Neuroscience letters. vol 74. issue 3. 1987-05-08. PMID:2436113. |
the hypothalamus was examined in 3 cases of alzheimer's disease and 3 control brains, using combined acetylcholinesterase (ache) and thioflavin-s staining. |
1987-05-08 |
2023-08-11 |
rat |
| R Elble, E Giacobini, G F Scarsell. Cholinesterases in cerebrospinal fluid. A longitudinal study in Alzheimer disease. Archives of neurology. vol 44. issue 4. 1987-04-17. PMID:3827696. |
we measured acetylcholinesterase (ache) and butyrylcholinesterase activities in the lumbar cerebrospinal fluid (csf) of 39 patients with dementia of alzheimer type and 21 age-matched controls. |
1987-04-17 |
2023-08-11 |
Not clear |
| R Elble, E Giacobini, G F Scarsell. Cholinesterases in cerebrospinal fluid. A longitudinal study in Alzheimer disease. Archives of neurology. vol 44. issue 4. 1987-04-17. PMID:3827696. |
our results and those of previous studies demonstrate that csf ache is not a useful diagnostic marker of alzheimer disease. |
1987-04-17 |
2023-08-11 |
Not clear |
| G S Zubenko, J K Marquis, L Volicer, L K Direnfeld, P J Langlais, R A Nixo. Cerebrospinal fluid levels of angiotensin-converting enzyme, acetylcholinesterase, and dopamine metabolites in dementia associated with Alzheimer's disease and Parkinson's disease: a correlative study. Biological psychiatry. vol 21. issue 14. 1987-02-13. PMID:3024746. |
mean levels of the two hydrolases angiotensin-converting enzyme (ace) and acetylcholinesterase (ache), the dopamine metabolites dihydroxyphenylacetic acid (dopac) and homovanillic acid (hva), and total protein concentration were examined in cerebrospinal fluid (csf) samples from a group of patients with dementia of the alzheimer's type, a group of comparably demented patients with parkinson's disease, and a neurologically healthy elderly control group. |
1987-02-13 |
2023-08-11 |
human |
| G S Zubenko, J K Marquis, L Volicer, L K Direnfeld, P J Langlais, R A Nixo. Cerebrospinal fluid levels of angiotensin-converting enzyme, acetylcholinesterase, and dopamine metabolites in dementia associated with Alzheimer's disease and Parkinson's disease: a correlative study. Biological psychiatry. vol 21. issue 14. 1987-02-13. PMID:3024746. |
independent of csf protein concentration, ace activity per milliliter exhibited a positive correlation with ache activity per milliliter within the control and parkinson's disease groups, whereas a statistically significant correlation for these csf hydrolases was not observed within the alzheimer's disease group. |
1987-02-13 |
2023-08-11 |
human |
| E G McGeer, P L McGeer, H Kamo, H Tago, R Harro. Cortical metabolism, acetylcholinesterase staining and pathological changes in Alzheimer's disease. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 13. issue 4 Suppl. 1987-02-06. PMID:2431752. |
acetylcholinesterase (ache) staining of the cerebral cortex in elderly normals and alzheimer's disease cases with a new, highly sensitive method showed that in alzheimer's disease there was an extensive loss of ache-positive fibers with senile plaques frequently incorporating ache-positive fiber debris. |
1987-02-06 |
2023-08-11 |
Not clear |
| C G Gottfries, T Bartfai, A Carlsson, S Eckernäs, L Svennerhol. Multiple biochemical deficits in both gray and white matter of Alzheimer brains. Progress in neuro-psychopharmacology & biological psychiatry. vol 10. issue 3-5. 1987-02-06. PMID:3797685. |
in the brains from the alzheimer patients the examination of gray matter (caudate nucleus and hippocampus) showed a significant reduced activity of choline-acetyl transferase (cat) and a reduction of acetylcholinesterase (ache) that bordered significance in the hippocampus. |
1987-02-06 |
2023-08-11 |
cat |
| S Nakano, T Kato, S Nakamura, M Kameyam. Acetylcholinesterase activity in cerebrospinal fluid of patients with Alzheimer's disease and senile dementia. Journal of the neurological sciences. vol 75. issue 2. 1986-11-20. PMID:3760912. |
ache activity in the csf was significantly lower in patients with presenile dementia (alzheimer's disease), compared with age-matched control subjects (p less than 0.001). |
1986-11-20 |
2023-08-11 |
human |
| S Gomez, P Davous, P Rondot, A Faivre-Bauman, D Valade, J Puymira. Somatostatin-like immunoreactivity and acetylcholinesterase activities in cerebrospinal fluid of patients with Alzheimer disease and senile dementia of the Alzheimer type. Psychoneuroendocrinology. vol 11. issue 1. 1986-06-13. PMID:3517922. |
somatostatin-like immunoreactivity (sli) and acetylcholinesterase (ache) activities were measured in the cerebrospinal fluid of 25 patients with senile dementia of the alzheimer type (sdat). |
1986-06-13 |
2023-08-11 |
Not clear |
| D M St Clair, D J Brock, L Barro. A monoclonal antibody assay technique for plasma and red cell acetylcholinesterase activity in Alzheimer's disease. Journal of the neurological sciences. vol 73. issue 2. 1986-06-11. PMID:2939202. |
acetylcholinesterases (ache) in human plasma and red cells have been considered as possible markers for alzheimer's disease. |
1986-06-11 |
2023-08-11 |
human |
| D M St Clair, D J Brock, L Barro. A monoclonal antibody assay technique for plasma and red cell acetylcholinesterase activity in Alzheimer's disease. Journal of the neurological sciences. vol 73. issue 2. 1986-06-11. PMID:2939202. |
ache activity in plasma and red cells was assayed in alzheimer's disease, multi-infarct dementia, huntington's and alcoholic korsakoff syndrome, and the results compared both between groups and with normal controls. |
1986-06-11 |
2023-08-11 |
human |
| D M St Clair, D J Brock, L Barro. A monoclonal antibody assay technique for plasma and red cell acetylcholinesterase activity in Alzheimer's disease. Journal of the neurological sciences. vol 73. issue 2. 1986-06-11. PMID:2939202. |
our findings do not suggest that in the dementias peripheral ache activity reflects altered central cholinergic function, nor that it is likely to prove a useful marker for alzheimer's disease. |
1986-06-11 |
2023-08-11 |
human |
| E B Fishman, G C Siek, R D MacCallum, E D Bird, L Volicer, J K Marqui. Distribution of the molecular forms of acetylcholinesterase in human brain: alterations in dementia of the Alzheimer type. Annals of neurology. vol 19. issue 3. 1986-04-28. PMID:3963769. |
the distribution of ache molecular forms was defined by sucrose density gradients of 11 anatomical regions of postmortem brains from 10 patients with dementia of the alzheimer type (dat) and 14 nondemented controls of similar ages. |
1986-04-28 |
2023-08-11 |
human |
| S T DeKosky, S W Scheff, W R Markesber. Laminar organization of cholinergic circuits in human frontal cortex in Alzheimer's disease and aging. Neurology. vol 35. issue 10. 1985-10-21. PMID:4033925. |
cholinergic enzyme activity (choline acetyltransferase, cat; acetylcholinesterase, ache) and muscarinic cholinergic receptor density were measured in frontal cortex (brodmann's area 9) of normal patients over the life span and in brains of patients with alzheimer's disease (ad). |
1985-10-21 |
2023-08-11 |
human |
| J K Marquis, L Volicer, K A Mark, L K Direnfeld, M Freedma. Cholinesterase activity in plasma, erythrocytes, and cerebrospinal fluid of patients with dementia of the Alzheimer type. Biological psychiatry. vol 20. issue 6. 1985-07-08. PMID:3995108. |
cholinesterases, including pseudocholinesterase (bche) of human plasma and acetylcholinesterase (ache) of erythrocytes and cerebrospinal fluid (csf), have been considered as possible markers in dementia of the alzheimer type (dat). |
1985-07-08 |
2023-08-11 |
human |
| L Tune, S Gucker, M Folstein, L Oshida, J T Coyl. Cerebrospinal fluid acetylcholinesterase activity in senile dementia of the Alzheimer type. Annals of neurology. vol 17. issue 1. 1985-04-26. PMID:3985585. |
acetylcholinesterase (ache) activity was measured in cerebrospinal fluid (csf) samples from 36 individuals, including 12 persons with alzheimer's disease, 12 normal controls, and 12 patients with other dementias. |
1985-04-26 |
2023-08-11 |
human |
| L Tune, S Gucker, M Folstein, L Oshida, J T Coyl. Cerebrospinal fluid acetylcholinesterase activity in senile dementia of the Alzheimer type. Annals of neurology. vol 17. issue 1. 1985-04-26. PMID:3985585. |
csf from patients with senile dementia of the alzheimer type showed significantly lower mean ache activity than in age-matched controls and patients with other dementia syndromes. |
1985-04-26 |
2023-08-11 |
human |
| L Tune, S Gucker, M Folstein, L Oshida, J T Coyl. Cerebrospinal fluid acetylcholinesterase activity in senile dementia of the Alzheimer type. Annals of neurology. vol 17. issue 1. 1985-04-26. PMID:3985585. |
no correlation was found between duration of illness, age, or severity of illness (as measured by the mini-mental state examination score) and csf ache activity in alzheimer's disease. |
1985-04-26 |
2023-08-11 |
human |
| L Tune, S Gucker, M Folstein, L Oshida, J T Coyl. Cerebrospinal fluid acetylcholinesterase activity in senile dementia of the Alzheimer type. Annals of neurology. vol 17. issue 1. 1985-04-26. PMID:3985585. |
csf ache activity may prove to be a useful diagnostic test to confirm the clinical diagnosis of moderate to severe alzheimer's disease. |
1985-04-26 |
2023-08-11 |
human |
| S Lal, P L Wood, M E Kiely, P Etienne, S Gauthier, J Stratford, R M Ford, D Dastoor, N P Nai. CSF acetylcholinesterase in dementia and in sequential samples of lumbar CSF. Neurobiology of aging. vol 5. issue 4. 1985-04-26. PMID:6531064. |
acetylcholinesterase (ache) activity (nmol/ml/min) was measured in lumbar csf from 11 patients with dementia of the alzheimer type (dat), 8 patients with korsakoff psychosis and 33 patients with low back pain who were undergoing myelography (controls). |
1985-04-26 |
2023-08-12 |
Not clear |