Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Oluwaseun Samuel Faborode, Ernest Dalle, Musa Vuyisile Mabandl. Inescapable footshocks induce molecular changes in the prefrontal cortex of rats in an amyloid-beta-42 model of Alzheimer's disease. Behavioural brain research. vol 419. 2021-12-10. PMID:34826515. |
alzheimer's disease (ad) affects several brain areas, including the prefrontal cortex (pfc) involved in execution, working memory, and fear extinction. |
2021-12-10 |
2023-08-13 |
rat |
Eunho Kim, Jin-Woo Yu, Bomin Kim, Sung-Ho Lim, Sang-Ho Lee, Kwangsu Kim, Gowoon Son, Hyeon-Ae Jeon, Cheil Moon, Joon Sakong, Ji-Woong Cho. Refined prefrontal working memory network as a neuromarker for Alzheimer's disease. Biomedical optics express. vol 12. issue 11. 2021-12-04. PMID:34858710. |
refined prefrontal working memory network as a neuromarker for alzheimer's disease. |
2021-12-04 |
2023-08-13 |
Not clear |
Yanan Qiao, Yu Sun, Jing Guo, Yaojing Chen, Wenjie Hou, Junying Zhang, Dantao Pen. Disrupted White Matter Integrity and Cognitive Functions in Amyloid-β Positive Alzheimer's Disease with Concomitant Lobar Cerebral Microbleeds. Journal of Alzheimer's disease : JAD. 2021-11-29. PMID:34842192. |
lobar cerebral microbleeds (cmbs), which can impair white matter (wm), are often concomitant with definite alzheimer's disease (ad). |
2021-11-29 |
2023-08-13 |
Not clear |
Mi Sook Lee, Bo Seon Ki. Effects of working memory intervention on language production by individuals with dementia. Neuropsychological rehabilitation. vol 31. issue 10. 2021-11-25. PMID:32677586. |
the purpose of this study was to investigate the effects of working memory intervention on language production by people with mild or moderate alzheimer's disease (ad). |
2021-11-25 |
2023-08-13 |
Not clear |
Mohammed Abubaker, Wiam Al Qasem, Eugen Kvašňá. Working Memory and Cross-Frequency Coupling of Neuronal Oscillations. Frontiers in psychology. vol 12. 2021-11-10. PMID:34744934. |
the reduced wm capacity is a common feature in many diseases, such as schizophrenia, attention deficit hyperactivity disorder (adhd), mild cognitive impairment (mci), and alzheimer's disease (ad). |
2021-11-10 |
2023-08-13 |
Not clear |
Benjamin B Tournier, Cristina Barca, Aïda B Fall, Yesica Gloria, Léa Meyer, Kelly Ceyzériat, Philippe Mille. Spatial reference learning deficits in absence of dysfunctional working memory in the TgF344-AD rat model of Alzheimer's disease. Genes, brain, and behavior. vol 20. issue 5. 2021-11-09. PMID:33150709. |
spatial reference learning deficits in absence of dysfunctional working memory in the tgf344-ad rat model of alzheimer's disease. |
2021-11-09 |
2023-08-13 |
human |
Fanny Gaubert, Hanna Chaina. Decision-Making Competence in Patients with Alzheimer's Disease: A Review of the Literature. Neuropsychology review. vol 31. issue 2. 2021-10-28. PMID:33576942. |
in this review, we focus on dmc in patients with alzheimer's disease (ad) and the links its impairment could have with deficits in episodic memory, working memory, and executive functions. |
2021-10-28 |
2023-08-13 |
Not clear |
Maurizio Bergamino, Ryan R Walsh, Ashley M Stoke. Free-water diffusion tensor imaging improves the accuracy and sensitivity of white matter analysis in Alzheimer's disease. Scientific reports. vol 11. issue 1. 2021-10-20. PMID:33772083. |
in conclusion, fw-dti better reflects the underlying pathology of ad and improves the accuracy of dti metrics related to wm integrity in alzheimer's disease. |
2021-10-20 |
2023-08-13 |
Not clear |
I Colonna, M Koini, L Pirpamer, A Damulina, E Hofer, P Schwingenschuh, C Enzinger, R Schmidt, S Ropel. Microstructural Tissue Changes in Alzheimer Disease Brains: Insights from Magnetization Transfer Imaging. AJNR. American journal of neuroradiology. vol 42. issue 4. 2021-10-12. PMID:33509922. |
we aim to compare magnetization transfer ratio in global and regional gm and wm between individuals with alzheimer disease and healthy control participants to analyze the relationship between magnetization transfer ratio and cognitive functioning in alzheimer disease. |
2021-10-12 |
2023-08-13 |
human |
Hyunwoong Ko, Soyeon Kim, Kiwon Kim, Sang-Hyuk Jung, Injeong Shim, Soojin Cha, Hyewon Lee, Beomsu Kim, Joohyun Yoon, Tae Hyon Ha, Seyul Kwak, Jae Myeong Kang, Jun-Young Lee, Jinho Kim, Woong-Yang Park, Kwangsik Nho, Doh Kwan Kim, Woojae Myung, Hong-Hee Wo. Genome-wide association study of occupational attainment as a proxy for cognitive reserve. Brain : a journal of neurology. 2021-10-06. PMID:34613391. |
in two-sample mendelian randomization (mr) analysis, we demonstrated that high occupation levels were associated with reduced risk for alzheimer's disease (or = 0.78, 95% ci = 0.65-0.92 in inverse variance weighted (ivw) method; or = 0.73, 95% ci = 0.57-0.92 in the weighted median (wm) method). |
2021-10-06 |
2023-08-13 |
Not clear |
Hyunwoong Ko, Soyeon Kim, Kiwon Kim, Sang-Hyuk Jung, Injeong Shim, Soojin Cha, Hyewon Lee, Beomsu Kim, Joohyun Yoon, Tae Hyon Ha, Seyul Kwak, Jae Myeong Kang, Jun-Young Lee, Jinho Kim, Woong-Yang Park, Kwangsik Nho, Doh Kwan Kim, Woojae Myung, Hong-Hee Wo. Genome-wide association study of occupational attainment as a proxy for cognitive reserve. Brain : a journal of neurology. 2021-10-06. PMID:34613391. |
this causal relationship between occupational attainment and alzheimer's disease was robust in additional sensitivity analysis that excluded potentially pleiotropic snps (or = 0.72, 95% ci = 0.57-0.91 in the ivw method; or = 0.72, 95% ci = 0.53-0.97 in the wm method). |
2021-10-06 |
2023-08-13 |
Not clear |
Hyunwoong Ko, Soyeon Kim, Kiwon Kim, Sang-Hyuk Jung, Injeong Shim, Soojin Cha, Hyewon Lee, Beomsu Kim, Joohyun Yoon, Tae Hyon Ha, Seyul Kwak, Jae Myeong Kang, Jun-Young Lee, Jinho Kim, Woong-Yang Park, Kwangsik Nho, Doh Kwan Kim, Woojae Myung, Hong-Hee Wo. Genome-wide association study of occupational attainment as a proxy for cognitive reserve. Brain : a journal of neurology. 2021-10-06. PMID:34613391. |
multivariable mr confirmed that occupational attainment had an independent effect on the risk for alzheimer's disease even after taking educational attainment into account (or = 0.72, 95% ci = 0.54-0.95 in the ivw method; or = 0.68, 95% ci = 0.48-0.97 in the wm method). |
2021-10-06 |
2023-08-13 |
Not clear |
Ryan A Wirt, Lauren A Crew, Andrew A Ortiz, Adam M McNeela, Emmanuel Flores, Jefferson W Kinney, James M Hyma. Altered theta rhythm and hippocampal-cortical interactions underlie working memory deficits in a hyperglycemia risk factor model of Alzheimer's disease. Communications biology. vol 4. issue 1. 2021-09-24. PMID:34480097. |
altered theta rhythm and hippocampal-cortical interactions underlie working memory deficits in a hyperglycemia risk factor model of alzheimer's disease. |
2021-09-24 |
2023-08-13 |
human |
Anna M Pietroboni, Annalisa Colombi, Tiziana Carandini, Elio Scarpini, Daniela Galimberti, Marco Bozzal. The Role of Amyloid-β in White Matter Damage: Possible Common Pathogenetic Mechanisms in Neurodegenerative and Demyelinating Diseases. Journal of Alzheimer's disease : JAD. vol 78. issue 1. 2021-09-20. PMID:32925075. |
just as multiple sclerosis (ms) has long been primarily considered a white matter (wm) disease, alzheimer's disease (ad) has for decades been regarded only as a grey matter disorder. |
2021-09-20 |
2023-08-13 |
Not clear |
Hedok Lee, Feng Xu, Xiaodan Liu, Sunil Koundal, Xiaoyue Zhu, Judianne Davis, David Yanez, Joseph Schrader, Aleksandra Stanisavljevic, Douglas L Rothman, Joanna Wardlaw, William E Van Nostrand, Helene Benvenist. Diffuse white matter loss in a transgenic rat model of cerebral amyloid angiopathy. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 41. issue 5. 2021-07-29. PMID:32791876. |
in humans, csvd such as cerebral amyloid angiopathy (caa) often coexists with alzheimer's disease imposing a significant impediment for characterizing their distinct effects on wm. |
2021-07-29 |
2023-08-13 |
rat |
Kyoungwon Baik, Jin-Ju Yang, Jin Ho Jung, Yang Hyun Lee, Seok Jong Chung, Han Soo Yoo, Young H Sohn, Phil Hyu Lee, Jong-Min Lee, Byoung Seok Y. Structural connectivity networks in Alzheimer's disease and Lewy body disease. Brain and behavior. vol 11. issue 5. 2021-06-30. PMID:33792194. |
we evaluated disruption of the white matter (wm) network related with alzheimer's disease (ad) and lewy body disease (lbd), which includes parkinson's disease and dementia with lewy bodies. |
2021-06-30 |
2023-08-13 |
Not clear |
Jilu P Mole, Fabrizio Fasano, John Evans, Rebecca Sims, Derek A Hamilton, Emma Kidd, Claudia Metzler-Baddele. Genetic risk of dementia modifies obesity effects on white matter myelin in cognitively healthy adults. Neurobiology of aging. vol 94. 2021-06-29. PMID:32736120. |
these findings suggest that genetic risk modifies the impact of obesity on wm myelin consistent with neuroglia models of aging and late-onset alzheimer's disease. |
2021-06-29 |
2023-08-13 |
Not clear |
Alexander J Beagle, Ali Zahir, Mia Borzello, Andrew S Kayser, Ming Hsu, Bruce L Miller, Joel H Kramer, Winston Chion. Amount and delay insensitivity during intertemporal choice in three neurodegenerative diseases reflects dorsomedial prefrontal atrophy. Cortex; a journal devoted to the study of the nervous system and behavior. vol 124. 2021-06-21. PMID:31837518. |
patients with alzheimer's disease and other dementias often make poor financial decisions, but it remains unclear whether this reflects specific failures in decision-making or more general deficits in episodic and working memory. |
2021-06-21 |
2023-08-13 |
human |
David Foxe, Muireann Irish, Daniel Roquet, Angela Scharfenberg, Nathan Bradshaw, John R Hodges, James R Burrell, Olivier Pigue. Visuospatial short-term and working memory disturbance in the primary progressive aphasias: Neuroanatomical and clinical implications. Cortex; a journal devoted to the study of the nervous system and behavior. vol 132. 2021-06-21. PMID:32998062. |
here, we investigated the short-term and working memory profiles of the ppa variants and typical alzheimer's disease (ad), with a particular interest in the visuospatial system. |
2021-06-21 |
2023-08-13 |
Not clear |
Geng-Di Huang, Li-Xin Jiang, Feng Su, Hua-Li Wang, Chen Zhang, Xin Y. A novel paradigm for assessing olfactory working memory capacity in mice. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:33319773. |
a decline in working memory (wm) capacity is suggested to be one of the earliest symptoms observed in alzheimer's disease (ad). |
2021-06-18 |
2023-08-13 |
mouse |