| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A J Glasky, C L Melchior, B Pirzadeh, N Heydari, R F Ritzman. Effect of AIT-082, a purine analog, on working memory in normal and aged mice. Pharmacology, biochemistry, and behavior. vol 47. issue 2. 1994-05-02. PMID:8146224. |
because working memory is the primary type of memory which is disrupted by alzheimer's disease and stroke and during aging, any therapeutic drug for these conditions should improve and/or restore working memory. |
1994-05-02 |
2023-08-12 |
mouse |
| A J Glasky, C L Melchior, B Pirzadeh, N Heydari, R F Ritzman. Effect of AIT-082, a purine analog, on working memory in normal and aged mice. Pharmacology, biochemistry, and behavior. vol 47. issue 2. 1994-05-02. PMID:8146224. |
ait-082 was devoid of any effects on performance variables and has not shown any toxic side effects, thus making it an interesting potential treatment for working memory deficits associated with aging, strokes, and alzheimer's disease. |
1994-05-02 |
2023-08-12 |
mouse |
| R F Ritzmann, A Kling, C L Melchior, A J Glask. Effect of age and strain on working memory in mice as measured by win-shift paradigm. Pharmacology, biochemistry, and behavior. vol 44. issue 4. 1993-05-11. PMID:8469692. |
working memory is disrupted in alzheimer's disease and stroke; therefore, any therapeutic drug should restore deficits in working memory. |
1993-05-11 |
2023-08-12 |
mouse |
| A D Baddeley, S Bressi, S Della Sala, R Logie, H Spinnle. The decline of working memory in Alzheimer's disease. A longitudinal study. Brain : a journal of neurology. vol 114 ( Pt 6). 1992-03-18. PMID:1782529. |
the decline of working memory in alzheimer's disease. |
1992-03-18 |
2023-08-11 |
Not clear |
| A D Baddeley, S Bressi, S Della Sala, R Logie, H Spinnle. The decline of working memory in Alzheimer's disease. A longitudinal study. Brain : a journal of neurology. vol 114 ( Pt 6). 1992-03-18. PMID:1782529. |
a previous study (baddeley et al., 1986) explored the hypothesis that patients suffering from dementia of the alzheimer type (ad) are particularly impaired in the functioning of the central executive component of working memory. |
1992-03-18 |
2023-08-11 |
Not clear |
| J T Becke. Working memory and secondary memory deficits in Alzheimer's disease. Journal of clinical and experimental neuropsychology. vol 10. issue 6. 1989-04-28. PMID:3235648. |
working memory and secondary memory deficits in alzheimer's disease. |
1989-04-28 |
2023-08-11 |
Not clear |