Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Rebeca Scalco, Luca C Oliveira, Zhengfeng Lai, Danielle J Harvey, Lana Abujamil, Charles DeCarli, Lee-Way Jin, Chen-Nee Chuah, Brittany N Dugge. Machine learning quantification of Amyloid-β deposits in the temporal lobe of 131 brain bank cases. Acta neuropathologica communications. vol 12. issue 1. 2024-08-17. PMID:39154006. |
utilizing 131 whole-slide-images from consecutive autopsied cases at the university of california davis alzheimer disease research center, our objectives were threefold: (1) validate an automatic workflow for aβ deposit quantification in white matter (wm) and gray matter (gm); (2) define the distributions of different aβ deposit types in gm and wm, and (3) investigate correlates of aβ deposits with dementia status and the presence of mixed pathology. |
2024-08-17 |
2024-08-20 |
Not clear |
Yi Jiang, Xin Zhang, Zhiwei Guo, Ning Jian. Altered EEG Theta and Alpha Band Functional Connectivity in Mild Cognitive Impairment During Working Memory coding. IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society. vol PP. 2024-06-21. PMID:38905095. |
individuals with mild cognitive impairment (mci), the preclinical stage of alzheimer disease (ad), suffer decline in their visual working memory (wm) functions. |
2024-06-21 |
2024-06-24 |
Not clear |
Lucía Rodríguez-Fernández, Candela Zorzo, Jorge L Aria. Photobiomodulation in the aging brain: a systematic review from animal models to humans. GeroScience. 2024-06-11. PMID:38861125. |
in healthy aged humans, it has been outlined improvements in working memory, cognitive inhibition, and lexical/semantic access, while general cognition was mainly enhanced on alzheimer disease or mild cognitive impairment. |
2024-06-11 |
2024-06-14 |
Not clear |
Mario Tranfa, Luigi Lorenzini, Lyduine E Collij, David Vállez García, Silvia Ingala, Giuseppe Pontillo, Leonard Pieperhoff, Alessio Maranzano, Robin Wolz, Sven Haller, Kaj Blennow, Giovanni Frisoni, Carole H Sudre, Gael Chételat, Michael Ewers, Pierre Payoux, Adam Waldman, Pablo Martinez-Lage, Adam J Schwarz, Craig W Ritchie, Joanna M Wardlaw, Juan Domingo Gispert, Arturo Brunetti, Henk J M M Mutsaerts, Alle Meije Wink, Frederik Barkho. Alzheimer's Disease and Small Vessel Disease Differentially Affect White Matter Microstructure. Annals of clinical and translational neurology. 2024-05-17. PMID:38757392. |
alzheimer's disease (ad) and cerebral small vessel disease (csvd), the two most common causes of dementia, are characterized by white matter (wm) alterations diverging from the physiological changes occurring in healthy aging. |
2024-05-17 |
2024-05-27 |
Not clear |
Rami Lee, Ji-Hun Kim, Won-Woo Kim, Sung-Hee Hwang, Sun-Hye Choi, Jong-Hoon Kim, Ik-Hyun Cho, Manho Kim, Seung-Yeol Na. Emerging evidence that ginseng components improve cognition in subjective memory impairment, mild cognitive impairment, and early Alzheimer's disease dementia. Journal of ginseng research. vol 48. issue 3. 2024-05-06. PMID:38707644. |
clinical studies have also shown that acute or long-term intake of ginseng total extract improves acute working memory performance or cognitive function in healthy individuals and those with subjective memory impairment (smi), mild cognitive impairment (mci), or early alzheimer's disease (ad) dementia who are taking ad medication(s). |
2024-05-06 |
2024-05-08 |
Not clear |
Jie Deng, Hong Wang, Tingting Fu, Chong Xu, Qiqi Zhu, Liya Guo, Yu Zh. Physical activity improves the visual-spatial working memory of individuals with mild cognitive impairment or Alzheimer's disease: a systematic review and network meta-analysis. Frontiers in public health. vol 12. 2024-04-12. PMID:38605880. |
physical activity improves the visual-spatial working memory of individuals with mild cognitive impairment or alzheimer's disease: a systematic review and network meta-analysis. |
2024-04-12 |
2024-04-14 |
Not clear |
Jie Deng, Hong Wang, Tingting Fu, Chong Xu, Qiqi Zhu, Liya Guo, Yu Zh. Physical activity improves the visual-spatial working memory of individuals with mild cognitive impairment or Alzheimer's disease: a systematic review and network meta-analysis. Frontiers in public health. vol 12. 2024-04-12. PMID:38605880. |
our network meta-analysis aimed to ascertain the effect of physical activity on the visual-spatial working memory of individuals with mild cognitive impairment and alzheimer's disease as well as to propose tailored exercise interventions for each group. |
2024-04-12 |
2024-04-14 |
Not clear |
Jeffrey S Phillips, Nagesh Adluru, Moo K Chung, Hamsanandini Radhakrishnan, Christopher A Olm, Philip A Cook, James C Gee, Katheryn A Q Cousins, Sanaz Arezoumandan, David A Wolk, Corey T McMillan, Murray Grossman, David J Irwi. Greater white matter degeneration and lower structural connectivity in non-amnestic vs. amnestic Alzheimer's disease. Frontiers in neuroscience. vol 18. 2024-04-03. PMID:38567286. |
multimodal evidence indicates alzheimer's disease (ad) is characterized by early white matter (wm) changes that precede overt cognitive impairment. |
2024-04-03 |
2024-04-05 |
Not clear |
Khazar Ahmadi, Joana B Pereira, Danielle van Westen, Ofer Pasternak, Fan Zhang, Markus Nilsson, Erik Stomrud, Nicola Spotorno, Oskar Hansso. Fixel-based analysis reveals tau-related white matter changes in early stages of Alzheimer's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-04-02. PMID:38565289. |
several studies have shown white matter (wm) abnormalities in alzheimer's disease (ad) using diffusion tensor imaging (dti). |
2024-04-02 |
2024-04-05 |
Not clear |
Om Roy, Yashar Moshfeghi, Agustin Ibanez, Francisco Lopera, Mario A Parra, Keith M Smit. FAST functional connectivity implicates P300 connectivity in working memory deficits in Alzheimer's disease. ArXiv. 2024-03-11. PMID:38463502. |
fast functional connectivity implicates p300 connectivity in working memory deficits in alzheimer's disease. |
2024-03-11 |
2024-03-14 |
human |
Yilu Li, Jinzhong Peng, Zhenzhen Yang, Fanyu Zhang, Lin Liu, Pan Wang, Bharat B Biswa. Altered white matter functional pathways in Alzheimer's disease. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 3. 2024-03-04. PMID:38436465. |
alzheimer's disease (ad) is associated with functional disruption in gray matter (gm) and structural damage to white matter (wm), but the relationship to functional signal in wm is unknown. |
2024-03-04 |
2024-03-06 |
Not clear |
Qing Wang, Suzanne E Schindler, Gengsheng Chen, Nicole S Mckay, Austin McCullough, Shaney Flores, Jingxia Liu, Zhexian Sun, Sicheng Wang, Wenshang Wang, Jason Hassenstab, Carlos Cruchaga, Richard J Perrin, Anne M Fagan, John C Morris, Yong Wang, Tammie L S Benzinge. Investigating White Matter Neuroinflammation in Alzheimer Disease Using Diffusion-Based Neuroinflammation Imaging. Neurology. vol 102. issue 4. 2024-02-05. PMID:38315956. |
alzheimer disease (ad) is primarily associated with accumulations of amyloid plaques and tau tangles in gray matter, however, it is now acknowledged that neuroinflammation, particularly in white matter (wm), significantly contributes to the development and progression of ad. |
2024-02-05 |
2024-02-09 |
Not clear |
Shengnan Zhang, Hongrui Ai, Jia Wang, Tiaotiao Liu, Xuyuan Zheng, Xin Tian, Wenwen Ba. Reduced Prefrontal-Thalamic Theta Flow During Working Memory Retrieval in APP/PS1 Mice. Journal of Alzheimer's disease : JAD. 2024-02-02. PMID:38306044. |
working memory deficits in alzheimer's disease (ad) are linked to impairments in the retrieval of stored memory information. |
2024-02-02 |
2024-02-04 |
mouse |
Shengnan Zhang, Hongrui Ai, Jia Wang, Tiaotiao Liu, Xuyuan Zheng, Xin Tian, Wenwen Ba. Reduced Prefrontal-Thalamic Theta Flow During Working Memory Retrieval in APP/PS1 Mice. Journal of Alzheimer's disease : JAD. 2024-02-02. PMID:38306044. |
however, research on the mechanism of impaired working memory retrieval in alzheimer's disease is still lacking. |
2024-02-02 |
2024-02-04 |
mouse |
Lauren R Hirschfeld, Rachael Deardorff, Evgeny J Chumin, Yu-Chien Wu, Brenna C McDonald, Sha Cao, Shannon L Risacher, Dahyun Yi, Min Soo Byun, Jun-Young Lee, Yu Kyeong Kim, Koung Mi Kang, Chul-Ho Sohn, Kwangsik Nho, Andrew J Saykin, Dong Young Le. White matter integrity is associated with cognition and amyloid burden in older adult Koreans along the Alzheimer's disease continuum. Alzheimer's research & therapy. vol 15. issue 1. 2023-12-16. PMID:38102714. |
white matter (wm) microstructural changes in the hippocampal cingulum bundle (cbh) in alzheimer's disease (ad) have been described in cohorts of largely european ancestry but are lacking in other populations. |
2023-12-16 |
2023-12-18 |
Not clear |
Renée C Groechel, Michael L Alosco, Diane Dixon, Yorghos Tripodis, Jesse Mez, Lee Goldstein, Andrew E Budson, Wei Qiao Qiu, Ronald J Killian. Associations between white matter integrity of the cingulum bundle, surrounding gray matter regions, and cognition across the dementia continuum. The Journal of comparative neurology. 2023-11-27. PMID:38010204. |
previous alzheimer's disease and related dementias (ad/adrd) research studies have illustrated the significance of studying alterations in white matter (wm). |
2023-11-27 |
2023-11-29 |
human |
Won Jong Chwa, Cyrus A Raji, Kat Toups, Ann Hathaway, Deborah Gordon, Henrianna Chung, Alan Boyd, Benjamin D Hill, Sharon Hausman-Cohen, Mouna Attarha, Michael Jarrett, Dale E Bredese. Longitudinal White and Gray Matter Response to Precision Medicine-Guided Intervention for Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 96. issue 3. 2023-11-26. PMID:38007669. |
alzheimer's disease (ad) is a debilitating condition that is widely known to adversely affect gray matter (gm) and white matter (wm) tracts within the brain. |
2023-11-26 |
2023-11-28 |
Not clear |
Masoumeh Gholami, Mehdi Sadegh, Masoumeh Koroush-Arami, Shaghayegh Norouzi, Rasoul Jafari Arismani, Erfan Asadi, Mohammad Amini, Nahid Khodayar. Targeting memory loss with aspirin, a molecular mechanism perspective for future therapeutic approaches. Inflammopharmacology. 2023-11-04. PMID:37924473. |
the inhibition of cox-1 might potentially prevent impairments in working memory and reduce neuroinflammation caused by beta-amyloid proteins in some conditions, such as alzheimer's disease (ad). |
2023-11-04 |
2023-11-08 |
Not clear |
Dana M Parker, Jenna N Adams, Soyun Kim, Liv McMillan, Michael A Yass. NODDI-derived measures of microstructural integrity in medial temporal lobe white matter pathways are associated with Alzheimer's disease pathology and cognitive outcomes. bioRxiv : the preprint server for biology. 2023-10-31. PMID:37905117. |
diffusion tensor imaging has been used to assess white matter (wm) changes in the early stages of alzheimer's disease (ad). |
2023-10-31 |
2023-11-08 |
Not clear |
Kaicheng Li, Shuyue Wang, Xiao Luo, Qingze Zeng, Xiaocao Liu, Luwei Hong, Jixuan Li, Hui Hong, Xiaopei Xu, Yao Zhang, Yeerfan Jiaerken, Ruiting Zhang, Linyun Xie, Shan Xu, Xinyi Zhang, Yanxing Chen, Zhirong Liu, Minming Zhang, Peiyu Huan. Associations of Alzheimer's Disease Pathology and Small Vessel Disease With Cerebral White Matter Degeneration: A Tract-Based MR Diffusion Imaging Study. Journal of magnetic resonance imaging : JMRI. 2023-09-22. PMID:37737474. |
white matter (wm) degeneration is a key feature of alzheimer's disease (ad). |
2023-09-22 |
2023-10-07 |
Not clear |