| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Bianchini, A Di Vita, L Palermo, L Piccardi, C Blundo, C Guarigli. A selective egocentric topographical working memory deficit in the early stages of Alzheimer's disease: a preliminary study. American journal of Alzheimer's disease and other dementias. vol 29. issue 8. 2015-07-10. PMID:24906969. |
the aim of this study was to determine whether an egocentric topographical working memory (wm) deficit is present in the early stages of alzheimer's disease (ad) with respect to other forms of visuospatial wm. |
2015-07-10 |
2023-08-13 |
human |
| Katrin Morgen, Michael Schneider, Lutz Frölich, Heike Tost, Michael M Plichta, Heike Kölsch, Fabian Rakebrandt, Otto Rienhoff, Frank Jessen, Oliver Peters, Holger Jahn, Christian Luckhaus, Michael Hüll, Hermann-Josef Gertz, Johannes Schröder, Harald Hampel, Stefan J Teipel, Johannes Pantel, Isabella Heuser, Jens Wiltfang, Eckart Rüther, Johannes Kornhuber, Wolfgang Maier, Andreas Meyer-Lindenber. Apolipoprotein E-dependent load of white matter hyperintensities in Alzheimer's disease: a voxel-based lesion mapping study. Alzheimer's research & therapy. vol 7. issue 1. 2015-05-18. PMID:25984242. |
white matter (wm) magnetic resonance imaging (mri) hyperintensities are common in alzheimer's disease (ad), but their pathophysiological relevance and relationship to genetic factors are unclear. |
2015-05-18 |
2023-08-13 |
Not clear |
| Jagan A Pillai, Aaron Bonner-Jackson, Esteban Walker, Lyla Mourany, Jeffrey L Cumming. Higher working memory predicts slower functional decline in autopsy-confirmed Alzheimer's disease. Dementia and geriatric cognitive disorders. vol 38. issue 3-4. 2015-05-12. PMID:24903099. |
higher working memory predicts slower functional decline in autopsy-confirmed alzheimer's disease. |
2015-05-12 |
2023-08-13 |
Not clear |
| Elizabeth G Kehoe, Dervla Farrell, Claudia Metzler-Baddeley, Brian A Lawlor, Rose Anne Kenny, Declan Lyons, Jonathan P McNulty, Paul G Mullins, Damien Coyle, Arun L Bokd. Fornix White Matter is Correlated with Resting-State Functional Connectivity of the Thalamus and Hippocampus in Healthy Aging but Not in Mild Cognitive Impairment - A Preliminary Study. Frontiers in aging neuroscience. vol 7. 2015-02-20. PMID:25698967. |
in this study, we wished to examine the relationship between the structural connectivity of the fornix, a white matter (wm) tract in the limbic system, which is affected in amnestic mild cognitive impairment (amci) and alzheimer's disease, and the resting-state functional connectivity (fc) of two key related subcortical structures, the thalamus, and hippocampus. |
2015-02-20 |
2023-08-13 |
Not clear |
| Jeremy Koppel, Suzanne Sunday, Terry E Goldberg, Peter Davies, Erica Christen, Blaine S Greenwal. Psychosis in Alzheimer's disease is associated with frontal metabolic impairment and accelerated decline in working memory: findings from the Alzheimer's Disease Neuroimaging Initiative. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 22. issue 7. 2015-02-19. PMID:23672944. |
psychosis in alzheimer's disease is associated with frontal metabolic impairment and accelerated decline in working memory: findings from the alzheimer's disease neuroimaging initiative. |
2015-02-19 |
2023-08-12 |
human |
| Brian T Gold, Zude Zhu, Christopher A Brown, Anders H Andersen, Mary Jo LaDu, Leon Tai, Greg A Jicha, Richard J Kryscio, Steven Estus, Peter T Nelson, Steve W Scheff, Erin Abner, Frederick A Schmitt, Linda J Van Eldik, Charles D Smit. White matter integrity is associated with cerebrospinal fluid markers of Alzheimer's disease in normal adults. Neurobiology of aging. vol 35. issue 10. 2015-02-09. PMID:24866404. |
we explored whether white matter (wm) integrity in cognitively normal (cn) older adults is associated with cerebrospinal fluid (csf) markers of alzheimer's disease pathology. |
2015-02-09 |
2023-08-13 |
Not clear |
| Brian T Gold, Zude Zhu, Christopher A Brown, Anders H Andersen, Mary Jo LaDu, Leon Tai, Greg A Jicha, Richard J Kryscio, Steven Estus, Peter T Nelson, Steve W Scheff, Erin Abner, Frederick A Schmitt, Linda J Van Eldik, Charles D Smit. White matter integrity is associated with cerebrospinal fluid markers of Alzheimer's disease in normal adults. Neurobiology of aging. vol 35. issue 10. 2015-02-09. PMID:24866404. |
our results link lower wm microstructural integrity in cn older adults with csf biomarkers of alzheimer's disease and suggest that this association in the fornix may be independent of volumetric measures. |
2015-02-09 |
2023-08-13 |
Not clear |
| Jing Liao, Yue Zhu, Meiyan Zhang, Huishu Yuan, Min-Ying Su, Xin Yu, Huali Wan. Microstructural white matter abnormalities independent of white matter lesion burden in amnestic mild cognitive impairment and early Alzheimer disease among Han Chinese elderly. Alzheimer disease and associated disorders. vol 24. issue 4. 2015-02-06. PMID:20592582. |
this study was designed to evaluate the microstructural integrity of white matter (wm) in amnestic mild cognitive impairment (mci) and alzheimer's disease (ad) among han chinese elderly using diffusion tensor imaging (dti) technique, and to investigate the relationship between wm abnormalities and cognitive dysfunction. |
2015-02-06 |
2023-08-12 |
human |
| Navid Shiee, Pierre-Louis Bazin, Jennifer L Cuzzocreo, Chuyang Ye, Bhaskar Kishore, Aaron Carass, Peter A Calabresi, Daniel S Reich, Jerry L Prince, Dzung L Pha. Reconstruction of the human cerebral cortex robust to white matter lesions: method and validation. Human brain mapping. vol 35. issue 7. 2015-01-22. PMID:24382742. |
cortical atrophy has been reported in a number of diseases, such as multiple sclerosis and alzheimer's disease, that are also associated with white matter (wm) lesions. |
2015-01-22 |
2023-08-12 |
human |
| Jessica M Foley, David H Salat, Nikki H Stricker, Tyler A Zink, Laura J Grande, Regina E McGlinchey, William P Milberg, Elizabeth C Lerit. Interactive effects of apolipoprotein E4 and diabetes risk on later myelinating white matter regions in neurologically healthy older aged adults. American journal of Alzheimer's disease and other dementias. vol 29. issue 3. 2015-01-12. PMID:24381137. |
possession of the apolipoprotein e4 (apoe4) allele and diabetes risk are independently related to reduced white matter (wm) integrity that may contribute to the development of alzheimer's disease (ad). |
2015-01-12 |
2023-08-12 |
Not clear |
| Vanja Kljajevic, Peter Meyer, Carsten Holzmann, Martin Dyrba, Elisabeth Kasper, Arun L W Bokde, Andreas Fellgiebel, Thomas Meindl, Harald Hampel, Stefan Teipe. The ε4 genotype of apolipoprotein E and white matter integrity in Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 10. issue 3. 2014-12-10. PMID:23706516. |
in this multicenter study, we investigated a possible association between the apoe ε4 allele and white matter (wm) integrity in alzheimer's disease (ad) using diffusion tensor imaging (dti). |
2014-12-10 |
2023-08-12 |
Not clear |
| Naruhiko Sahara, Pablo D Perez, Wen-Lang Lin, Dennis W Dickson, Yan Ren, Huadong Zeng, Jada Lewis, Marcelo Feb. Age-related decline in white matter integrity in a mouse model of tauopathy: an in vivo diffusion tensor magnetic resonance imaging study. Neurobiology of aging. vol 35. issue 6. 2014-11-25. PMID:24411290. |
elevated expression of human hyperphosphorylated tau is associated with neuronal loss and white matter (wm) pathology in alzheimer's disease (ad) and related neurodegenerative disorders. |
2014-11-25 |
2023-08-12 |
mouse |
| Gerardo Fernández, Jochen Laubrock, Pablo Mandolesi, Oscar Colombo, Osvaldo Agamennon. Registering eye movements during reading in Alzheimer's disease: difficulties in predicting upcoming words. Journal of clinical and experimental neuropsychology. vol 36. issue 3. 2014-11-07. PMID:24580505. |
several of the associated cognitive processes such as working memory and semantic memory are known to be impaired by alzheimer's disease (ad). |
2014-11-07 |
2023-08-12 |
Not clear |
| Illana Gozes, Yulie Schirer, Anat Idan-Feldman, Merav David, Sharon Furman-Assa. NAP alpha-aminoisobutyric acid (IsoNAP). Journal of molecular neuroscience : MN. vol 52. issue 1. 2014-09-25. PMID:24458740. |
nap (napvsipq, intranasal formulation al-108) is a drug candidate that (1) had a statistically significant impact on two measures, namely digit span and delayed-match-to-sample, tests of verbal recall and visual working memory, respectively, in patient population of mild cognitive impairment [preceding alzheimer's disease (ad)] and (2) protected functional activities of daily living in schizophrenia patients. |
2014-09-25 |
2023-08-12 |
mouse |
| Nicola Mammarella, Beth Fairfiel. Emotional working memory and Alzheimer's disease. International journal of Alzheimer's disease. vol 2014. 2014-06-24. PMID:24639911. |
emotional working memory and alzheimer's disease. |
2014-06-24 |
2023-08-12 |
Not clear |
| Nicola Mammarella, Beth Fairfiel. Emotional working memory and Alzheimer's disease. International journal of Alzheimer's disease. vol 2014. 2014-06-24. PMID:24639911. |
here, we review behavioural and neuroimaging evidence that points to a complex interaction between emotion modulation and working memory in alzheimer's. |
2014-06-24 |
2023-08-12 |
Not clear |
| Nicola Mammarella, Beth Fairfiel. Emotional working memory and Alzheimer's disease. International journal of Alzheimer's disease. vol 2014. 2014-06-24. PMID:24639911. |
we interpret this complex pattern of results as a consequence of the interaction between multiple factors including the severity of alzheimer's disease, the nature of affective stimuli, and type of working memory task. |
2014-06-24 |
2023-08-12 |
Not clear |
| Lucas S Broster, Juan Li, Charles D Smith, Gregory A Jicha, Frederick A Schmitt, Yang Jian. Repeated retrieval during working memory is sensitive to amnestic mild cognitive impairment. Journal of clinical and experimental neuropsychology. vol 35. issue 9. 2014-06-09. PMID:24074205. |
contextual working memory impairment may represent a novel predictor of alzheimer disease conversion risk. |
2014-06-09 |
2023-08-12 |
Not clear |
| Evan Fletcher, Owen Carmichael, Ofer Pasternak, Klaus H Maier-Hein, Charles DeCarl. Early Brain Loss in Circuits Affected by Alzheimer's Disease is Predicted by Fornix Microstructure but may be Independent of Gray Matter. Frontiers in aging neuroscience. vol 6. 2014-06-06. PMID:24904414. |
in a cohort of community-recruited elderly subjects with normal cognition at initial evaluation, we found that baseline fornix white matter (wm) microstructure was significantly correlated with early volumetric longitudinal tissue change across a region of interest (called fornix significant roi, fsroi), which overlaps circuits known to be selectively vulnerable to alzheimer's dementia pathology. |
2014-06-06 |
2023-08-13 |
human |
| Wei Zhou, Guifa Zhong, Xiurong Rao, Hui Xie, Shaogao Zeng, Tianyan Chi, Libo Zou, Donghai Wu, Wenhui H. Identification of aminopyridazine-derived antineuroinflammatory agents effective in an Alzheimer's mouse model. ACS medicinal chemistry letters. vol 3. issue 11. 2014-06-05. PMID:24900405. |
compound 14 was finally identified as an effective agent with comparable in vivo efficacy to the marketed drug donepezil in counteracting spatial learning and working memory impairment in an aβ-induced alzheimer's mouse model. |
2014-06-05 |
2023-08-13 |
mouse |