| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Murakami, T Mori, K Koshimura, M Kurosaki, T Hori, N Yanaihara, Y Kat. Stimulation by urocortin of growth hormone (GH) secretion in GH-producing human pituitary adenoma cells. Endocrine journal. vol 44. issue 4. 1998-03-13. PMID:9447301. |
these preliminary findings suggest that type-2 crh receptors are expressed in some population of gh-producing human pituitary adenoma cells and that ucn might be involved in gh secretion from tumorous tissues in patients with acromegaly. |
1998-03-13 |
2023-08-12 |
human |
| G Lombardi, A Colao, A Cuocolo, S Longobardi, C Di Somma, F Orio, B Merola, E Nicolai, M Salvator. Cardiological aspects of growth hormone and insulin-like growth factor-I. Journal of pediatric endocrinology & metabolism : JPEM. vol 10. issue 6. 1998-03-12. PMID:9467124. |
these abnormalities of the cardiovascular system are partially reversed after normalization of gh and igf-i levels, by octreotide in acromegaly or after gh replacement therapy in ghd patients. |
1998-03-12 |
2023-08-12 |
Not clear |
| R Abs, J Verhelst, D Maiter, K Van Acker, F Nobels, J L Coolens, C Mahler, A Becker. Cabergoline in the treatment of acromegaly: a study in 64 patients. The Journal of clinical endocrinology and metabolism. vol 83. issue 2. 1998-02-27. PMID:9467544. |
the results of this study suggest that cabergoline is an effective, well tolerated therapy that should be considered in the management of acromegaly, especially if the pituitary adenoma cosecretes gh and prl or if pretreatment plasma igf-i levels are below 750 micrograms/l. |
1998-02-27 |
2023-08-12 |
Not clear |
| W Saeger, D K Lüdecke, M Los. [Combined neuronal and endocrine tumors of the sellar region]. Der Pathologe. vol 18. issue 6. 1998-02-26. PMID:9451729. |
as only the adenomas can secrete gh, the adenomas and not the gangliocytomas are directly responsible for acromegaly so that such an adenoma has to be present in cases of acromegaly. |
1998-02-26 |
2023-08-12 |
Not clear |
| F Jockenhövel, S Rohrbach, S Deggerich, D Reinwein, C Reiner. Differential presentation of cortical and trabecular peripheral bone mineral density in acromegaly. European journal of medical research. vol 1. issue 8. 1998-02-17. PMID:9360937. |
the differential mineralization of cortical and trabecular bone in acromegaly may be indicative of the detrimental effect accompanying pituitary insufficiency can have on trabecular bone, despite substitution therapy, but could also be due to different reactivity of cortical and trabecular bone to gh and/or igf i. |
1998-02-17 |
2023-08-12 |
Not clear |
| F Jockenhövel, S Rohrbach, S Deggerich, D Reinwein, C Reiner. Differential presentation of cortical and trabecular peripheral bone mineral density in acromegaly. European journal of medical research. vol 1. issue 8. 1998-02-17. PMID:9360937. |
the observable increase of bone mineral density in acromegaly suggests a potential use for gh in treating osteoporosis. |
1998-02-17 |
2023-08-12 |
Not clear |
| K Prank, M Wagner, G Braban. Algorithmic complexity of growth hormone release in humans. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 1998-01-15. PMID:9390305. |
in healthy humans growth hormone (gh) secretion is characterized by distinct pulses whereas patients bearing a gh producing tumor accompanied with excessive secretion (acromegaly) exhibit a highly irregular pattern of gh release. |
1998-01-15 |
2023-08-12 |
human |
| K Prank, M Wagner, G Braban. Algorithmic complexity of growth hormone release in humans. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 1998-01-15. PMID:9390305. |
it has been hypothesized that this highly disorderly pattern of gh release in acromegaly arises from random events in the gh-producing tumor under decreased normal control of gh secretion. |
1998-01-15 |
2023-08-12 |
human |
| K Prank, M Wagner, G Braban. Algorithmic complexity of growth hormone release in humans. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 1998-01-15. PMID:9390305. |
using a context-free grammar complexity measure (algorithmic complexity) in conjunction with random surrogate data sets we demonstrate that the temporal pattern of gh release in acromegaly is not significantly different from a variety of stochastic processes. |
1998-01-15 |
2023-08-12 |
human |
| K Prank, M Wagner, G Braban. Algorithmic complexity of growth hormone release in humans. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 1998-01-15. PMID:9390305. |
our results support the hypothesis that gh release in acromegaly is due to random events in the gh-producing tumorous cells which might become independent from hypothalamic regulation. |
1998-01-15 |
2023-08-12 |
human |
| R Cozzi, R Attanasio, G Oppizzi, P Orlandi, A Giustina, S Lodrini, N Da Re, D Dallabonzan. Effects of tamoxifen on GH and IGF-I levels in acromegaly. Journal of endocrinological investigation. vol 20. issue 8. 1998-01-07. PMID:9364247. |
effects of tamoxifen on gh and igf-i levels in acromegaly. |
1998-01-07 |
2023-08-12 |
Not clear |
| R Cozzi, R Attanasio, G Oppizzi, P Orlandi, A Giustina, S Lodrini, N Da Re, D Dallabonzan. Effects of tamoxifen on GH and IGF-I levels in acromegaly. Journal of endocrinological investigation. vol 20. issue 8. 1998-01-07. PMID:9364247. |
these data prompted us to evaluate gh and igf-i changes in acromegaly after acute and chronic tam administration. |
1998-01-07 |
2023-08-12 |
Not clear |
| A J van der Lely, W W de Herder, J A Janssen, S W Lambert. Acromegaly: the significance of serum total and free IGF-I and IGF-binding protein-3 in diagnosis. The Journal of endocrinology. vol 155 Suppl 1. 1997-12-15. PMID:9389990. |
however, in our series of patients, mean 24 h serum gh levels, igfbp-3, total and free igf-i do not correlate with disease activity in acromegaly. |
1997-12-15 |
2023-08-12 |
Not clear |
| G Lombardi, A Colao, P Marzullo, D Ferone, S Longobardi, V Esposito, B Merol. Is growth hormone bad for your heart? Cardiovascular impact of GH deficiency and of acromegaly. The Journal of endocrinology. vol 155 Suppl 1. 1997-12-15. PMID:9389993. |
cardiovascular impact of gh deficiency and of acromegaly. |
1997-12-15 |
2023-08-12 |
Not clear |
| S M Shalet, B M Brennan, R E Reddingiu. Growth hormone therapy and malignancy. Hormone research. vol 48 Suppl 4. 1997-12-09. PMID:9350443. |
concern arises from animal experiments, the association of acromegaly with malignancy, and the japanese experience of a cluster of de novo leukaemia cases in children treated with gh. |
1997-12-09 |
2023-08-12 |
human |
| G Lombardi, A Colao, D Ferone, P Marzullo, F Orio, S Longobardi, B Merol. Effect of growth hormone on cardiac function. Hormone research. vol 48 Suppl 4. 1997-12-09. PMID:9350445. |
cardiac function is reported to improve during octreotide and gh replacement treatment in acromegaly and ghd, respectively. |
1997-12-09 |
2023-08-12 |
Not clear |
| M Kovacs, R D Kineman, A V Schally, M Zarandi, K Groot, L A Frohma. Effects of antagonists of growth hormone-releasing hormone (GHRH) on GH and insulin-like growth factor I levels in transgenic mice overexpressing the human GHRH gene, an animal model of acromegaly. Endocrinology. vol 138. issue 11. 1997-11-24. PMID:9348175. |
effects of antagonists of growth hormone-releasing hormone (ghrh) on gh and insulin-like growth factor i levels in transgenic mice overexpressing the human ghrh gene, an animal model of acromegaly. |
1997-11-24 |
2023-08-12 |
mouse |
| M Kovacs, R D Kineman, A V Schally, M Zarandi, K Groot, L A Frohma. Effects of antagonists of growth hormone-releasing hormone (GHRH) on GH and insulin-like growth factor I levels in transgenic mice overexpressing the human GHRH gene, an animal model of acromegaly. Endocrinology. vol 138. issue 11. 1997-11-24. PMID:9348175. |
transgenic mice overexpressing the human gh-releasing hormone (hghrh) gene, an animal model of acromegaly, were used to investigate the effects of potent ghrh antagonists mz-4-71 and mz-5-156 on the excessive gh and insulin-like growth factor i (igf-i) secretion caused by overproduction of hghrh. |
1997-11-24 |
2023-08-12 |
mouse |
| E Pellegrini, D F Carmignac, M T Bluet-Pajot, F Mounier, P Bennett, J Epelbaum, I C Robinso. Intrahypothalamic growth hormone feedback: from dwarfism to acromegaly in the rat. Endocrinology. vol 138. issue 11. 1997-11-24. PMID:9348176. |
this experimental approach now makes it possible to study the effects of pathophysiological concentrations of gh ranging from dwarfism to acromegaly in the same animal model. |
1997-11-24 |
2023-08-12 |
rat |
| A L Barkan, I Halasz, K J Dornfeld, C A Jaffe, R D Friberg, W F Chandler, H M Sandle. Pituitary irradiation is ineffective in normalizing plasma insulin-like growth factor I in patients with acromegaly. The Journal of clinical endocrinology and metabolism. vol 82. issue 10. 1997-11-17. PMID:9329336. |
pituitary irradiation suppresses gh hypersecretion in patients with acromegaly. |
1997-11-17 |
2023-08-12 |
Not clear |