| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I Fukuda, N Hizuka, K Takano, T Kazama, Y Okubo, K Asakawa-Yasumoto, H Demur. Growth hormone (GH) receptor and IGF-I receptor messenger RNA expression in peripheral lymphocytes from patients with GH deficiency and acromegaly. Endocrine journal. vol 45 Suppl. 1999-01-06. PMID:9790242. |
growth hormone (gh) receptor and igf-i receptor messenger rna expression in peripheral lymphocytes from patients with gh deficiency and acromegaly. |
1999-01-06 |
2023-08-12 |
Not clear |
| R Martinez, G Bravo, J Burzaco, G Re. Pituitary tumors and gamma knife surgery. Clinical experience with more than two years of follow-up. Stereotactic and functional neurosurgery. vol 70 Suppl 1. 1998-12-18. PMID:9782242. |
all the tumors showed either a reduction in volume or cessation of growth; 85% of the patients with acromegaly showed normalization of growth hormone (gh) levels. |
1998-12-18 |
2023-08-12 |
Not clear |
| P M Boulou. Somatuline LA: a new treatment for acromegaly. Hospital medicine (London, England : 1998). vol 59. issue 8. 1998-12-03. PMID:9829060. |
the introduction of somatuline la, a long acting formulation which controls plasma gh levels for up to 14 days and improves acromegaly symptoms, is likely to improve patient compliance and quality of life. |
1998-12-03 |
2023-08-12 |
Not clear |
| P U Freda, K D Post, J S Powell, S L Wardla. Evaluation of disease status with sensitive measures of growth hormone secretion in 60 postoperative patients with acromegaly. The Journal of clinical endocrinology and metabolism. vol 83. issue 11. 1998-11-25. PMID:9814451. |
traditionally, suppression of gh measured by polyclonal ria to less than 2.0 microg/l after oral glucose was accepted as evidence of remission after transsphenoidal surgery for acromegaly. |
1998-11-25 |
2023-08-12 |
human |
| P U Freda, K D Post, J S Powell, S L Wardla. Evaluation of disease status with sensitive measures of growth hormone secretion in 60 postoperative patients with acromegaly. The Journal of clinical endocrinology and metabolism. vol 83. issue 11. 1998-11-25. PMID:9814451. |
there has, however, never been a systematic comparison of sensitive gh, igf-i, and igfbp-3 assays in defining disease status in a large cohort of postoperative patients with acromegaly. |
1998-11-25 |
2023-08-12 |
human |
| P U Freda, K D Post, J S Powell, S L Wardla. Evaluation of disease status with sensitive measures of growth hormone secretion in 60 postoperative patients with acromegaly. The Journal of clinical endocrinology and metabolism. vol 83. issue 11. 1998-11-25. PMID:9814451. |
sixty postoperative subjects with acromegaly and 25 age-matched healthy subjects were evaluated with nadir gh levels after 100 g oral glucose as well as baseline igf-i and igfbp-3 levels. |
1998-11-25 |
2023-08-12 |
human |
| P U Freda, K D Post, J S Powell, S L Wardla. Evaluation of disease status with sensitive measures of growth hormone secretion in 60 postoperative patients with acromegaly. The Journal of clinical endocrinology and metabolism. vol 83. issue 11. 1998-11-25. PMID:9814451. |
subjects with acromegaly in remission included those with normal gh suppression (n = 23; mean nadir gh by irma, 0.10 +/- 0.006 microg/l) and others with abnormal gh suppression by irma (n = 15; mean nadir gh by irma, 0.35 +/- 0.07 microg/l). |
1998-11-25 |
2023-08-12 |
human |
| M Miyakawa, T Tsushima, H Murakami, O Isozaki, H Demura, T Tanak. Effect of growth hormone (GH) on serum concentrations of leptin: study in patients with acromegaly and GH deficiency. The Journal of clinical endocrinology and metabolism. vol 83. issue 10. 1998-11-05. PMID:9768649. |
effect of growth hormone (gh) on serum concentrations of leptin: study in patients with acromegaly and gh deficiency. |
1998-11-05 |
2023-08-12 |
human |
| M Miyakawa, T Tsushima, H Murakami, O Isozaki, H Demura, T Tanak. Effect of growth hormone (GH) on serum concentrations of leptin: study in patients with acromegaly and GH deficiency. The Journal of clinical endocrinology and metabolism. vol 83. issue 10. 1998-11-05. PMID:9768649. |
we have measured serum leptin levels and correlated them with several variables in patients with acromegaly, patients with adult gh deficiency (ghd), and normal controls. |
1998-11-05 |
2023-08-12 |
human |
| K Hanew, A Utsumi, A Tanaka, H Ikeda, Y Yokogosh. Secretory mechanisms of growth hormone (GH)-releasing peptide-, GH-releasing hormone-, and thyrotropin-releasing hormone-induced GH release in patients with acromegaly. The Journal of clinical endocrinology and metabolism. vol 83. issue 10. 1998-11-05. PMID:9768668. |
secretory mechanisms of growth hormone (gh)-releasing peptide-, gh-releasing hormone-, and thyrotropin-releasing hormone-induced gh release in patients with acromegaly. |
1998-11-05 |
2023-08-12 |
human |
| K Hanew, A Utsumi, A Tanaka, H Ikeda, Y Yokogosh. Secretory mechanisms of growth hormone (GH)-releasing peptide-, GH-releasing hormone-, and thyrotropin-releasing hormone-induced GH release in patients with acromegaly. The Journal of clinical endocrinology and metabolism. vol 83. issue 10. 1998-11-05. PMID:9768668. |
the gh secretory mechanism of gh-releasing hexapeptide (ghrp-6), ghrh, and trh were studied in vivo and in vitro in seven patients with acromegaly. |
1998-11-05 |
2023-08-12 |
human |
| M Korbonits, R A Jacobs, S J Aylwin, J M Burrin, P L Dahia, J P Monson, J Honegger, R Fahlbush, P J Trainer, S L Chew, G M Besser, A B Grossma. Expression of the growth hormone secretagogue receptor in pituitary adenomas and other neuroendocrine tumors. The Journal of clinical endocrinology and metabolism. vol 83. issue 10. 1998-11-05. PMID:9768675. |
patients with acromegaly show an exuberant gh response to ghss, whereas patients with pituitary-dependent acth-secreting tumors show an exaggerated rise in acth and cortisol. |
1998-11-05 |
2023-08-12 |
human |
| C B Newman, S Melmed, A George, D Torigian, M Duhaney, P Snyder, W Young, A Klibanski, M E Molitch, R Gagel, L Sheeler, D Cook, W Malarkey, I Jackson, M L Vance, A Barkan, L Frohman, D L Kleinber. Octreotide as primary therapy for acromegaly. The Journal of clinical endocrinology and metabolism. vol 83. issue 9. 1998-10-08. PMID:9745397. |
the dose was titrated by each investigator to improve each patient's individual response, which included improvement in symptoms and signs of acromegaly as well as reduction of gh and insulin-like growth factor i (igf-i) into the normal range. |
1998-10-08 |
2023-08-12 |
Not clear |
| J O Jørgensen, N Vahl, R Dall, J S Christianse. Resting metabolic rate in healthy adults: relation to growth hormone status and leptin levels. Metabolism: clinical and experimental. vol 47. issue 9. 1998-10-08. PMID:9751244. |
studies in patients with acromegaly and growth hormone (gh) deficiency, and administration of gh in normal and obese subjects and in patients with gh deficiency, suggest that gh increases resting metabolic rate (rmr) independently of changes in body composition. |
1998-10-08 |
2023-08-12 |
human |
| P Charalampaki, G Hildebrandt, H J Schaeffer, E Schönau, N Klu. Insulin-like growth factor binding protein-3 levels during early and late follow-up after surgery in acromegalic patients. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. vol 106. issue 2. 1998-09-10. PMID:9628244. |
disease activity in acromegaly is accurately reflected by growth hormone (gh) concentration during oral glucose tolerance test (ogtt) and insulin-like growth factor-i (igf-i) levels, representing an integrated index of gh activity. |
1998-09-10 |
2023-08-12 |
Not clear |
| S Melmed, I Jackson, D Kleinberg, A Klibansk. Current treatment guidelines for acromegaly. The Journal of clinical endocrinology and metabolism. vol 83. issue 8. 1998-09-02. PMID:9709926. |
acromegaly, an indolent disorder of growth hormone (gh) hypersecretion is most typically caused by a somatotroph cell adenoma and may be treated by several modalities. |
1998-09-02 |
2023-08-12 |
human |
| S Melmed, I Jackson, D Kleinberg, A Klibansk. Current treatment guidelines for acromegaly. The Journal of clinical endocrinology and metabolism. vol 83. issue 8. 1998-09-02. PMID:9709926. |
an integrated approach to acromegaly management based upon relative risks and benefits of the currently available therapeutic modes is presented that allows for a national individualized strategy designed to achieve maximal biochemical control of gh hypersecretion and elevated igf-i levels. |
1998-09-02 |
2023-08-12 |
human |
| S M Orme, R J McNally, R A Cartwright, P E Belchet. Mortality and cancer incidence in acromegaly: a retrospective cohort study. United Kingdom Acromegaly Study Group. The Journal of clinical endocrinology and metabolism. vol 83. issue 8. 1998-09-02. PMID:9709939. |
we, therefore, performed a multicenter retrospective cohort study of 1362 patients with acromegaly and investigated the relationships of mortality and cancer incidence with gh levels, duration of disease, and age at diagnosis. |
1998-09-02 |
2023-08-12 |
Not clear |
| S M Orme, R J McNally, R A Cartwright, P E Belchet. Mortality and cancer incidence in acromegaly: a retrospective cohort study. United Kingdom Acromegaly Study Group. The Journal of clinical endocrinology and metabolism. vol 83. issue 8. 1998-09-02. PMID:9709939. |
the overall mortality rate in patients with acromegaly with posttreatment gh levels less than 2.5 ng/ml (5 mu/l) was comparable to that in the general population of the united kingdom (standardized mortality ratio, 1.10; 95% ci, 0.89-1.35). |
1998-09-02 |
2023-08-12 |
Not clear |
| F Fallo, L Barzon, M Boscaro, E Casiglia, N Sonin. Effect of octreotide on 24-h blood pressure profile in acromegaly. American journal of hypertension. vol 11. issue 5. 1998-08-24. PMID:9633796. |
the aim of the study was to investigate the effect of octreotide, a somatostatin analog drug potentially able to inhibit growth hormone (gh), on the circadian blood pressure profile in a group of patients with acromegaly. |
1998-08-24 |
2023-08-12 |
Not clear |