| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vita Birzniece, Anne E Nelson, Ken K Y H. Growth hormone and physical performance. Trends in endocrinology and metabolism: TEM. vol 22. issue 5. 2011-08-11. PMID:21420315. |
in fact, there are adverse effects of long-term gh excess such that sustained abuse of gh can lead to a state mimicking acromegaly, a condition with increased morbidity and mortality. |
2011-08-11 |
2023-08-12 |
human |
| Mark Sherlock, Conor Woods, Michael C Sheppar. Medical therapy in acromegaly. Nature reviews. Endocrinology. vol 7. issue 5. 2011-08-01. PMID:21448141. |
acromegaly is a rare disease characterized by excess secretion of growth hormone (gh) and increased circulating insulin-like growth factor 1 (igf-1) concentrations. |
2011-08-01 |
2023-08-12 |
Not clear |
| Mark Sherlock, Conor Woods, Michael C Sheppar. Medical therapy in acromegaly. Nature reviews. Endocrinology. vol 7. issue 5. 2011-08-01. PMID:21448141. |
therapy for acromegaly is targeted at decreasing gh and igf-1 levels, ameliorating patients' symptoms and decreasing any local compressive effects of the pituitary adenoma. |
2011-08-01 |
2023-08-12 |
Not clear |
| Mark Sherlock, Conor Woods, Michael C Sheppar. Medical therapy in acromegaly. Nature reviews. Endocrinology. vol 7. issue 5. 2011-08-01. PMID:21448141. |
the therapeutic options for acromegaly include surgery, radiotherapy and medical therapies, such as dopamine agonists, somatostatin receptor ligands and the gh receptor antagonist pegvisomant. |
2011-08-01 |
2023-08-12 |
Not clear |
| Pedro Weslley Rosari. Measurement of basal GH in the diagnosis of acromegaly. Arquivos brasileiros de endocrinologia e metabologia. vol 54. issue 7. 2011-07-25. PMID:21085774. |
measurement of basal gh in the diagnosis of acromegaly. |
2011-07-25 |
2023-08-12 |
Not clear |
| Orsolya Nemes, Emese Mezos. [Role of somatostatin receptor ligands in the treatment of acromegaly--literature review]. Orvosi hetilap. vol 152. issue 18. 2011-05-27. PMID:21498160. |
the cornerstones of medical therapy in acromegaly are the somatostatin receptor ligands due to their effectiveness in controlling gh excess in 60-70 % of patients and their beneficial effects on tumor volume. |
2011-05-27 |
2023-08-12 |
Not clear |
| David R Clemmon. Clinical laboratory indices in the treatment of acromegaly. Clinica chimica acta; international journal of clinical chemistry. vol 412. issue 5-6. 2011-05-24. PMID:21075098. |
measurement of serum growth hormone (gh) and insulin-like growth factor-i (igf-) is used to monitor the degree of improvement that occurs following treatment of patients with acromegaly. |
2011-05-24 |
2023-08-12 |
human |
| P Kamenicky, M Lombès, P Chanso. [New insights in growth hormone physiology and pathophysiology]. Annales d'endocrinologie. vol 71 Suppl 1. 2011-05-20. PMID:21237327. |
finally, we will discuss the controversial issue of gh replacement in acromegalic patients presenting gh deficiency after treatment of acromegaly. |
2011-05-20 |
2023-08-12 |
Not clear |
| N Karavitaki, A Fernandez, V Fazal-Sanderson, J A H Was. The value of the oral glucose tolerance test, random serum growth hormone and mean growth hormone levels in assessing the postoperative outcome of patients with acromegaly. Clinical endocrinology. vol 71. issue 6. 2011-05-09. PMID:19320648. |
the nadir gh value following an oral glucose tolerance test (ogtt) and the mean gh levels obtained from a gh day curve (ghdc) are among the tools currently used for assessing therapeutic end-points in surgically treated acromegaly. |
2011-05-09 |
2023-08-12 |
Not clear |
| P Anil Kumar, Frank C Brosius, Ram K Meno. The glomerular podocyte as a target of growth hormone action: implications for the pathogenesis of diabetic nephropathy. Current diabetes reviews. vol 7. issue 1. 2011-04-27. PMID:21067510. |
gh excess in both the human (acromegaly) and in transgenic animal models is characterized by significant structural and functional changes in the kidney. |
2011-04-27 |
2023-08-12 |
human |
| Daria Baszko-Błaszyk, Julia Slynko, Włodzimierz Liebert, Piotr Sosnowski, Jerzy Sowiński, Ryszard Waśk. Difficulties in diagnosis and treatment of acromegaly in a patient with a McCune-Albright syndrome. A case report and a review of literature. Neuro endocrinology letters. vol 31. issue 5. 2011-04-18. PMID:21173751. |
only retrospectively, having biochemical confirmation of gh excess, we could relate them to acromegaly. |
2011-04-18 |
2023-08-12 |
Not clear |
| Ming Shen, Xuefei Shou, Yongfei Wang, Zhaoyun Zhang, Jinsong Wu, Ying Mao, Shiqi Li, Yao Zha. Effect of presurgical long-acting octreotide treatment in acromegaly patients with invasive pituitary macroadenomas: a prospective randomized study. Endocrine journal. vol 57. issue 12. 2011-04-11. PMID:21099129. |
therapeutic effects of presurgical long-acting octreotide treatment on tumor shrinkage, and short- and long-term postoperative gh and igf-1 levels of acromegaly patients with invasive pituitary macroadenomas were investigated prospectively in huashan hospital, shanghai, china. |
2011-04-11 |
2023-08-12 |
Not clear |
| Peter E Clayton, Indraneel Banerjee, Philip G Murray, Andrew G Reneha. Growth hormone, the insulin-like growth factor axis, insulin and cancer risk. Nature reviews. Endocrinology. vol 7. issue 1. 2011-04-06. PMID:20956999. |
although follow-up for the vast majority of these children does not yet extend beyond young adulthood, a slight increase in cancers in those with long-standing excess gh secretion (as seen in patients with acromegaly) and no overall increase in cancer with insulin treatment, have been observed. |
2011-04-06 |
2023-08-12 |
mouse |
| Graciela Stalldecker, Sabrina Diez, Graciela Pensi, Gladys Ovied. [Coexistence of acromegaloidism and lung cancer]. Medicina. vol 70. issue 3. 2011-04-04. PMID:20529776. |
acromegaloidism is a condition characterized by features of acromegaly without biochemical evidence of excessive growth hormone (gh) production. |
2011-04-04 |
2023-08-12 |
Not clear |
| Graciela Stalldecker, Sabrina Diez, Graciela Pensi, Gladys Ovied. [Coexistence of acromegaloidism and lung cancer]. Medicina. vol 70. issue 3. 2011-04-04. PMID:20529776. |
normal igf 1 and gh inhibition below 1 ng/ml by the oral glucose tolerance test ruled out the diagnosis of acromegaly. |
2011-04-04 |
2023-08-12 |
Not clear |
| Sebastian J C M M Neggers, Aart J van der Lel. Modulation of glucocorticoid metabolism by the GH-IGF-I axis. Endocrine development. vol 20. 2011-03-31. PMID:21164271. |
also, acromegaly and obesity can be better understood when this effect of insulin on liver sensitivity for gh is taken into account. |
2011-03-31 |
2023-08-12 |
Not clear |
| Tomasz Zatonski, Marek Bolanowski, Aleksandra Skrzypek, Monika Morawska-Kochman, Marcin Kaluzny, Katarzyna Zatonska, Krzysztof Moron, Roman Badowski, Tomasz Krecick. Evaluation of temporal bone computed tomography and paranasal sinuses magnetic resonance images in acromegalic patients. Neuro endocrinology letters. vol 31. issue 6. 2011-03-16. PMID:21206436. |
acromegaly is a rare disease, which symptoms are caused by excess secretion of a growth hormone (gh) from the anterior pituitary benign tumor - adenoma. |
2011-03-16 |
2023-08-12 |
Not clear |
| Simone Magnavita Sabino, Paulo Augusto Carvalho Miranda, Antonio Ribeiro-Oliveir. Growth hormone- secreting pituitary adenomas: from molecular basis to treatment options in acromegaly. Cancer biology & therapy. vol 9. issue 7. 2011-03-10. PMID:20234189. |
acromegaly is a disease of exaggerated somatic growth and distorted proportion arising from hypersecretion of growth hormone (gh) and insulin-like growth factor 1 (igf-1). |
2011-03-10 |
2023-08-12 |
Not clear |
| Hazem El-Bilbeisi, Mohammad Ghannam, Caramella F Nimri, Azmi T Ahma. Craniopharyngioma in a patient with acromegaly due to a pituitary macroadenoma. Annals of Saudi medicine. vol 30. issue 6. 2011-03-07. PMID:20864785. |
we present the first reported case of a craniopharyngioma as a second primary tumor in a patient with acromegaly due to a growth hormone (gh)-secreting pituitary adenoma. |
2011-03-07 |
2023-08-12 |
Not clear |
| Hazem El-Bilbeisi, Mohammad Ghannam, Caramella F Nimri, Azmi T Ahma. Craniopharyngioma in a patient with acromegaly due to a pituitary macroadenoma. Annals of Saudi medicine. vol 30. issue 6. 2011-03-07. PMID:20864785. |
we stress the need for close follow-up of patients with acromegaly with adequate control of gh and igf-1 levels. |
2011-03-07 |
2023-08-12 |
Not clear |