Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Dilek Berker, Serhat Isik, Yusuf Aydin, Yasemin Tutuncu, Gokhan Akdemir, Hatice Nursun Ozcan, Serdar Gule. Thyrotropin secreting pituitary adenoma accompanying a silent somatotropinoma. Turkish neurosurgery. vol 21. issue 3. 2011-12-21. PMID:21845579. |
we present a case with pituitary adenoma secreting both tsh and growth hormone (gh) with the prominent clinical findings of hyperthyroidism but without clinical findings of acromegaly. |
2011-12-21 |
2023-08-12 |
Not clear |
Lana A Del Porto, Simon V Liubinas, Andrew H Kay. Treatment of persistent and recurrent acromegaly. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 18. issue 2. 2011-12-05. PMID:21167718. |
acromegaly is a chronic insidious disease characterised by growth hormone (gh) hypersecretion, typically from a pituitary adenoma. |
2011-12-05 |
2023-08-12 |
Not clear |
Lana A Del Porto, Simon V Liubinas, Andrew H Kay. Treatment of persistent and recurrent acromegaly. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 18. issue 2. 2011-12-05. PMID:21167718. |
transsphenoidal adenoma resection is still the best first-line treatment for acromegaly but persistence (43%) or recurrence (2% to 3%) of gh hypersecretion after surgery remains a problem. |
2011-12-05 |
2023-08-12 |
Not clear |
Lana A Del Porto, Simon V Liubinas, Andrew H Kay. Treatment of persistent and recurrent acromegaly. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 18. issue 2. 2011-12-05. PMID:21167718. |
there has been a progressive lowering of the accepted gh level defining cure in acromegaly. |
2011-12-05 |
2023-08-12 |
Not clear |
S J Neggers, A J van der Lel. Pegvisomant and improvement of quality of life in acromegalic patients. Hormone research in paediatrics. vol 76 Suppl 1. 2011-12-05. PMID:21778759. |
acromegaly is a growth disorder, but mostly it is a metabolic disease related to excessive production of growth hormone (gh). |
2011-12-05 |
2023-08-12 |
Not clear |
Deepak Khandelwal, Rajesh Khadgawat, Amar Mukund, Ashish Sur. Acromegaly with no pituitary adenoma and no evidence of ectopic source. Indian journal of endocrinology and metabolism. vol 15 Suppl 3. 2011-11-10. PMID:22029034. |
more than 99% of patients with acromegaly harbor a growth hormone (gh) secreting pituitary adenoma. |
2011-11-10 |
2023-08-12 |
Not clear |
Deepak Khandelwal, Rajesh Khadgawat, Amar Mukund, Ashish Sur. Acromegaly with no pituitary adenoma and no evidence of ectopic source. Indian journal of endocrinology and metabolism. vol 15 Suppl 3. 2011-11-10. PMID:22029034. |
as the time from onset of signs/symptoms to diagnosis of acromegaly is long (symptom onset to diagnosis is often 4-10 years), pituitary adenomas that cause gh excess are often large and are nearly always visible on conventional magnetic resonance imaging (mri). |
2011-11-10 |
2023-08-12 |
Not clear |
Anna Krzentowska, Filip Gołkowski, Agata Bałdys-Waligórska, Alicja Hubalewska-Dydejczy. [Gastrointestinal tract polyps in acromegaly patients]. Przeglad lekarski. vol 67. issue 12. 2011-11-09. PMID:21591351. |
acromegaly is a rare, chronic disease due to hypersecretion of growth hormone (gh) by pituitary adenoma arising from somatotrophs. |
2011-11-09 |
2023-08-12 |
Not clear |
Anna Krzentowska, Filip Gołkowski, Agata Bałdys-Waligórska, Alicja Hubalewska-Dydejczy. [Gastrointestinal tract polyps in acromegaly patients]. Przeglad lekarski. vol 67. issue 12. 2011-11-09. PMID:21591351. |
our study indicates that duration of uncontrolled acromegaly, contrary to igf-1, gh basic and in ogtt serum concentrations at diagnosis are essential for the colon polyps development. |
2011-11-09 |
2023-08-12 |
Not clear |
Amir H Sam, Tricia Tan, Karim Meera. Insulin-mediated "pseudoacromegaly". Hormones (Athens, Greece). vol 10. issue 2. 2011-10-27. PMID:21724541. |
both somatic and metabolic features of acromegaly are due to excess growth hormone (gh) secretion and high serum concentrations of insulin-like growth factor-i (igf-i). |
2011-10-27 |
2023-08-12 |
Not clear |
Amir H Sam, Tricia Tan, Karim Meera. Insulin-mediated "pseudoacromegaly". Hormones (Athens, Greece). vol 10. issue 2. 2011-10-27. PMID:21724541. |
endocrinologists should consider this diagnosis when assessing patients with clinical features of acromegaly and insulin resistance, in the absence of elevated levels of gh and igf-i. |
2011-10-27 |
2023-08-12 |
Not clear |
Marcos P Manavela, Ariel Juri, Karina Danilowicz, Oscar D Brun. [Therapeutic management in 154 acromegalic patients]. Medicina. vol 70. issue 4. 2011-10-18. PMID:20679052. |
acromegaly is a chronic, invalidating disease due in over 95% of cases to a growth hormone (gh) secreting pituitary adenoma. |
2011-10-18 |
2023-08-12 |
Not clear |
Maria Fleseri. Clinical efficacy and safety results for dose escalation of somatostatin receptor ligands in patients with acromegaly: a literature review. Pituitary. vol 14. issue 2. 2011-09-27. PMID:21161602. |
in 90-95% of patients with acromegaly, the disease is caused by a growth hormone (gh)-secreting pituitary adenoma with elevated gh levels that ultimately induce excessive hepatic secretion of insulin-like growth factor-1 (igf-1). |
2011-09-27 |
2023-08-12 |
Not clear |
Maria Fleseri. Clinical efficacy and safety results for dose escalation of somatostatin receptor ligands in patients with acromegaly: a literature review. Pituitary. vol 14. issue 2. 2011-09-27. PMID:21161602. |
somatostatin receptor ligands (srls) are considered the standard medical choice for the treatment of acromegaly, and normalization of gh and igf-1 is attainable with effective therapy. |
2011-09-27 |
2023-08-12 |
Not clear |
A Ciresi, M C Amato, D Morreale, G Lodato, A Galluzzo, C Giordan. Cornea in acromegalic patients as a possible target of growth hormone action. Journal of endocrinological investigation. vol 34. issue 2. 2011-09-26. PMID:20651471. |
gh exerts its effects on many organs and the eye also seems to be a target site, although few authors have investigated the corneal thickness in patients with acromegaly. |
2011-09-26 |
2023-08-12 |
Not clear |
F Bogazzi, G Rossi, M Lombardi, F Raggi, C Urbani, C Sardella, C Cosci, E Martin. Effect of rosiglitazone on serum IGF-I concentrations in uncontrolled acromegalic patients under conventional medical therapy: results from a pilot phase 2 study. Journal of endocrinological investigation. vol 34. issue 2. 2011-09-26. PMID:20671417. |
high-dose thiazolidinediones have been reported to reduce serum gh levels in animal models of acromegaly. |
2011-09-26 |
2023-08-12 |
Not clear |
M D'Amore, G Minenna, S D'Amore, P Scagliusi, S Capri. [The strange case of a patient affected by acromegaly with osteoporomalacia without hypogonadism]. Reumatismo. vol 57. issue 4. 2011-08-30. PMID:16380758. |
acromegaly is a rare disease that, in the majority of cases, is due to the presence of a benign growth hormone (gh)-producing tumor of the pituitary. |
2011-08-30 |
2023-08-12 |
Not clear |
M D'Amore, G Minenna, S D'Amore, P Scagliusi, S Capri. [The strange case of a patient affected by acromegaly with osteoporomalacia without hypogonadism]. Reumatismo. vol 57. issue 4. 2011-08-30. PMID:16380758. |
in acromegaly, the skeletal effects of chronic gh excess have been mainly addressed by evaluating bone mineral density (bmd). |
2011-08-30 |
2023-08-12 |
Not clear |
Alisha N Wade, Jennifer Baccon, M Sean Grady, Kevin D Judy, Donald M O'Rourke, Peter J Snyde. Clinically silent somatotroph adenomas are common. European journal of endocrinology. vol 165. issue 1. 2011-08-22. PMID:21493729. |
somatotroph adenomas are typically recognized when they secrete gh excessively and cause acromegaly. |
2011-08-22 |
2023-08-12 |
Not clear |
T Gudbjartsson, B A Agnarsson, P S Palsson, A Johannesso. Acromegaly caused by ectopic growth hormone-releasing hormone production from a bronchial carcinoid tumor. The Thoracic and cardiovascular surgeon. vol 59. issue 3. 2011-08-18. PMID:21480145. |
acromegaly is usually caused by a growth hormone (gh)-secreting pituitary adenoma. |
2011-08-18 |
2023-08-12 |
Not clear |