| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J F Lipinski, B M Cohen, G S Zubenko, C M Waternau. Adrenoceptors and the pharmacology of affective illness: a unifying theory. Life sciences. vol 40. issue 20. 1987-06-23. PMID:2883548. |
the theory suggests that final effects on alpha-1 mediated neurotransmission may be produced not only by drugs which have direct effects on the alpha-1 receptor or its second messenger, but also by drugs having effects on neurotransmitter systems such as acetylcholine, gaba, and serotonin, among others, which modulate the activity of central norepinephrine neurons or, via feedback mechanisms, by drugs having effects on adrenergic receptors other than the alpha-1 receptor itself. |
1987-06-23 |
2023-08-11 |
Not clear |
| A D Kay, M B Schapiro, A K Riker, J V Haxby, S I Rapoport, N R Cutle. Cerebrospinal fluid monoaminergic metabolites are elevated in adults with Down's syndrome. Annals of neurology. vol 21. issue 4. 1987-06-19. PMID:2437853. |
under conditions of rest and a low monoamine diet, brain monoamine activity was examined in young (less than 35 years) and old (greater than 35 years) adults with down's syndrome and in control subjects by measuring the cerebrospinal fluid (csf) and plasma concentrations of the neurotransmitter norepinephrine, and of 5-hydroxyindoleacetic acid (5-hiaa), homovanillic acid (hva), and 3-methoxy 4-hydroxyphenylglycol (mhpg), the respective metabolites of the neurotransmitters serotonin, dopamine, and norepinephrine. |
1987-06-19 |
2023-08-11 |
human |
| L E Muske, R D Fernal. Control of a teleost social signal. II. Anatomical and physiological specializations of chromatophores. Journal of comparative physiology. A, Sensory, neural, and behavioral physiology. vol 160. issue 1. 1987-04-23. PMID:3820135. |
this physiological difference is correlated with a difference in the alpha adrenoceptor-mediated aggregation response of the cells in vitro: eyebar melanophores of barless males are significantly more responsive to physiological concentrations of the sympathetic neurotransmitter norepinephrine than those of barred males, and this intermorph difference appears to be unique to the eyebar color pattern. |
1987-04-23 |
2023-08-11 |
Not clear |
| Y Edoute, P M Vanhoutte, J T Shepher. Inorganic phosphate inhibits sympathetic neurotransmission in canine saphenous veins. The American journal of physiology. vol 252. issue 1 Pt 2. 1987-03-02. PMID:3028159. |
in strips of saphenous veins previously incubated with [3h]norepinephrine, the depression of the contractile response caused by phosphate during electrical stimulation was accompanied by a significant reduction in the overflow of labeled neurotransmitter. |
1987-03-02 |
2023-08-11 |
Not clear |
| W Schütz, D Magometschnig. A clinical approach for the identification of peripheral pre- and post-synaptic alpha-adrenergic receptors. Journal of hypertension. vol 4. issue 4. 1986-12-10. PMID:3021845. |
from the studies in which yohimbine was used it can be assumed that the post-synaptic response to norepinephrine is not counteracted by the drug-induced inhibition of sympathetic neurotransmitter release. |
1986-12-10 |
2023-08-11 |
human |
| S Steinlechner, T S King, T H Champney, B A Richardson, R J Reite. Pharmacological studies on the regulation of N-acetyltransferase activity and melatonin content of the pineal gland of the Syrian hamster. Journal of pineal research. vol 2. issue 2. 1986-05-14. PMID:3007727. |
neither a wide range of dosages of isoproterenol (0.5 mg/kg to 24 mg/kg), nor prolonged treatment with norepinephrine, the natural neurotransmitter, increased n-acetyltransferase (nat) activity or melatonin production. |
1986-05-14 |
2023-08-11 |
Not clear |
| H A Nasrallah, F J Dunner, M McCalley-Whitters, R E Smit. Pharmacologic probes of neurotransmitter systems in tardive dyskinesia: implications for clinical management. The Journal of clinical psychiatry. vol 47. issue 2. 1986-03-14. PMID:3003037. |
one possible reason for this is that there have been no serious attempts to define the role of major neurotransmitter systems (dopamine, norepinephrine, acetylcholine, serotonin, gaba) in one specific population of tardive dyskinesia patients. |
1986-03-14 |
2023-08-11 |
Not clear |
| J A Kessle. Differential regulation of peptide and catecholamine characters in cultured sympathetic neurons. Neuroscience. vol 15. issue 3. 1986-01-22. PMID:2415873. |
however, inhibition of neurotransmitter release with magnesium or calcium-free medium prevented the decrease in norepinephrine levels but not the decrease in substance p and somatostatin. |
1986-01-22 |
2023-08-11 |
rat |
| D P Taylor, M S Eison, L A Riblet, C P Vandermaele. Pharmacological and clinical effects of buspirone. Pharmacology, biochemistry, and behavior. vol 23. issue 4. 1986-01-07. PMID:2866549. |
recent evidence indicates that other neurotransmitter systems (serotonin, norepinephrine, acetylcholine) mediate buspirone's effects. |
1986-01-07 |
2023-08-11 |
Not clear |
| K Domańska-Janik, J Lazarewicz, K Noremberg, J Strosznajder, T Zalewsk. Metabolic disturbances of synaptosomes isolated from ischemic gerbil brain. Neurochemical research. vol 10. issue 5. 1985-08-22. PMID:2861577. |
the uptake of neurotransmitter substances, expressed as a percent of control value, was reduced 21% for norepinephrine, 40% for dopamine, 20% for choline, 24% for glutamate and 13% for gamma-aminobutyrate in ischemic synaptosomes. |
1985-08-22 |
2023-08-11 |
Not clear |
| V Tarizzo, M C Rubi. Effects of cocaine on several adrenergic system parameters. General pharmacology. vol 16. issue 1. 1985-04-26. PMID:2858432. |
the endogenous ventricular norepinephrine levels remain unchanged after acute injections of cocaine, but when the drug was administered chronically, the endogenous neurotransmitter content were augmented about 50%. |
1985-04-26 |
2023-08-11 |
rat |
| D Sugden, D C Klei. Regulation of rat pineal alpha 1-adrenoceptors. Journal of neurochemistry. vol 44. issue 1. 1985-01-23. PMID:2856885. |
together these results indicate that the pineal alpha 1-adrenoceptor, like the pineal beta-adrenoceptor, is regulated by sympathetic nerve activity, probably through the physiological release of the neurotransmitter norepinephrine. |
1985-01-23 |
2023-08-11 |
rat |
| I Hanin, M R Krigman, R B Mailma. Central neurotransmitter effects of organotin compounds: trials, tribulations and observations. Neurotoxicology. vol 5. issue 2. 1984-12-26. PMID:6150454. |
by measuring the concentrations of dopamine, norepinephrine, homovanillic acid, dihydroxyphenylacetic acid, gamma-aminobutyric acid, acetylcholine, and choline in different brain areas of tmt and tet-treated animals, an attempt was made to correlate these functional deficits with changes in cns neurotransmitter alterations in vivo. |
1984-12-26 |
2023-08-12 |
rat |
| M L Voorhess, M H MacGillivra. Low plasma norepinephrine responses to acute hypoglycemia in children with isolated growth hormone deficiency. The Journal of clinical endocrinology and metabolism. vol 59. issue 4. 1984-11-02. PMID:6384256. |
norepinephrine (ne) is a neurotransmitter of the sympathetic nervous system which is important in gh secretion. |
1984-11-02 |
2023-08-12 |
Not clear |
| D Atlas, Y Burstei. Isolation of an endogenous clonidine-displacing substance from rat brain. FEBS letters. vol 170. issue 2. 1984-07-18. PMID:6327389. |
in the course of isolation, cds was shown to be neither the endogenous neurotransmitter (-)norepinephrine (ne) nor the guanyl nucleotide gtp which lowers the specific binding of alpha 2-agonists to the alpha 2-adrenergic receptors. |
1984-07-18 |
2023-08-12 |
rat |
| R D Myers, T F Le. Calmodulin-induced feeding in the cat: attenuation by calcium chelator EGTA. The American journal of physiology. vol 246. issue 3 Pt 2. 1984-04-13. PMID:6422777. |
threshold doses of egta selectively attenuated cam-induced eating but not feeding elicited by the catecholamine neurotransmitter, norepinephrine. |
1984-04-13 |
2023-08-12 |
cat |
| H H Yeh, D J Woodwar. Noradrenergic action in the developing rat cerebellum: interaction between norepinephrine and synaptically-evoked responses of immature Purkinje cells. Brain research. vol 313. issue 2. 1984-04-12. PMID:6320981. |
this study was designed to characterize the influence of norepinephrine (ne), a putative cerebellar neurotransmitter, on immature synaptic activity during early postnatal periods of the developing cerebellar cortex. |
1984-04-12 |
2023-08-12 |
rat |
| M F Lokhandwala, M L Steenber. Selective activation by LY-141865 and apomorphine of presynaptic dopamine receptors in the rat kidney and influence of stimulation parameters in the action of dopamine. The Journal of pharmacology and experimental therapeutics. vol 228. issue 1. 1984-02-29. PMID:6694099. |
these results suggest that dopamine-induced inhibition of norepinephrine release depends on the conditions of stimulation, i.e., during lower frequencies of sympathetic nerve stimulation, inhibition occurs by simultaneous activation of both presynaptic dopamine receptors as well as alpha adrenoceptors, whereas only presynaptic dopamine receptors are responsible for the inhibition of neurotransmitter release caused by dopamine at the higher frequency of nerve stimulation. |
1984-02-29 |
2023-08-12 |
rat |
| H Fujiwara, Y Fujii, C Tanak. Labeled norepinephrine uptake and release in rat globus pallidus. Brain research. vol 279. issue 1-2. 1984-01-27. PMID:6315165. |
the uptake and release of [3h]norepinephrine [( 3h]ne) were investigated using isolated rat globus pallidus slices to determine the possible neurotransmitter role of this catecholamine. |
1984-01-27 |
2023-08-12 |
rat |
| E J Ariëns, A M Simoni. Physiological and pharmacological aspects of adrenergic receptor classification. Biochemical pharmacology. vol 32. issue 10. 1983-07-08. PMID:6134529. |
on the basis of a preference of beta 2- and alpha 2-adrenergic receptors for epinephrine, the hormone, and of beta 1-and alpha 1-receptors for norepinephrine, the neurotransmitter, it was postulated that the alpha 2- and beta 2-receptors are predominantly epinephrinergic in nature and located extrajunctionally and presynaptically whereas the alpha 1- and beta 1-receptors are predominantly norepinephrinergic in nature and located postsynaptically in the sympathetic terminal junction. |
1983-07-08 |
2023-08-12 |
Not clear |