| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A E Calogero, W T Gallucci, M A Kling, G P Chrousos, P W Gol. Cocaine stimulates rat hypothalamic corticotropin-releasing hormone secretion in vitro. Brain research. vol 505. issue 1. 1990-03-01. PMID:2611679. |
the psychomotor stimulant properties of cocaine are thought to be related to its ability to modify the metabolism and the activity of many neurotransmitter systems, such as acetylcholine (ach), serotonin (5-ht), norepinephrine (ne), and dopamine (da). |
1990-03-01 |
2023-08-11 |
rat |
| C W Bower. Expression of functional neurotransmitter receptors in an uninnervated tissue: avian amnion. Cell and tissue research. vol 258. issue 2. 1990-01-08. PMID:2555062. |
however, as assessed by contractile response, this tissue expressed at least 11 different types of receptor for neurotransmitter substances including acetylcholine, norepinephrine, histamine, 5-hydroxytryptamine, vasoactive intestinal peptide, urotensin ii, neurotensin, and somatostatin-28. |
1990-01-08 |
2023-08-11 |
Not clear |
| H Mori, T E Pisarri, G S Aldea, W K Husseini, M W Dae, M B Stevens, A C Hill, J C Coleridge, H M Coleridge, J I Hoffma. Usefulness and limitations of regional cardiac sympathectomy by phenol. The American journal of physiology. vol 257. issue 5 Pt 2. 1989-12-28. PMID:2574007. |
for at least 4 h after phenol application, intravenous infusion of isoproterenol or coronary arterial infusion of tyramine increased myocardial contractility in the denervated region; norepinephrine content and neurotransmitter uptake were normal, indicating that nerve terminals, postjunctional receptors, and myocardium remained functional. |
1989-12-28 |
2023-08-11 |
Not clear |
| S S Smith, M Neuringer, S R Ojed. Essential fatty acid deficiency delays the onset of puberty in the female rat. Endocrinology. vol 125. issue 3. 1989-09-20. PMID:2759037. |
this delay appears to be due at least in part to reduced prostaglandin e2 (pge2) synthesis, as the ability of the neurotransmitter norepinephrine to induce pge2 release from median eminence nerve terminals was markedly reduced in efa-deficient rats compared with that in controls. |
1989-09-20 |
2023-08-11 |
rat |
| A L Markowska, W S Stone, D K Ingram, J Reynolds, P E Gold, L H Conti, M J Pontecorvo, G L Wenk, D S Olto. Individual differences in aging: behavioral and neurobiological correlates. Neurobiology of aging. vol 10. issue 1. 1989-08-31. PMID:2569170. |
the following neurotransmitter markers were examined: choline acetyltransferase; the density of nicotinic, benzodiazepine and glutamine receptors in the cortex and caudate nucleus; endogenous levels of norepinephrine, dopamine, and serotonin in the cortex and hippocampus. |
1989-08-31 |
2023-08-11 |
rat |
| H A Navarro, F J Seidler, W L Whitmore, T A Slotki. Prenatal exposure to nicotine via maternal infusions: effects on development of catecholamine systems. The Journal of pharmacology and experimental therapeutics. vol 244. issue 3. 1989-08-10. PMID:3252040. |
comparisons with the results obtained with maternal nicotine injections (which produce largely stimulatory effects on norepinephrine levels and turnover) suggest that the hypoxia/ischemia associated with injected nicotine causes a reactive hyperinnervation; the adverse actions of nicotine on neurotransmitter development are thus highly dependent upon the route of drug administration. |
1989-08-10 |
2023-08-11 |
Not clear |
| V Kon, M J Karnovsk. Morphologic demonstration of adrenergic influences on the glomerulus. The American journal of pathology. vol 134. issue 5. 1989-06-20. PMID:2719073. |
to examine if morphologic changes analogous to those found in whole glomeruli can be demonstrated at the single cell level, the authors assessed the size of mesangial cells in vitro before, during, and after exposure to the adrenergic neurotransmitter, norepinephrine. |
1989-06-20 |
2023-08-11 |
rat |
| K A Haak, G Torres, P L Garvey, D M Bronstein, A K Cho, L D Lytl. Xylamine enhances pineal gland N-acetyltransferase activity in vitro. General pharmacology. vol 20. issue 1. 1989-06-02. PMID:2565274. |
since pineal gland uptake of radiolabelled norepinephrine (ne) was impaired by xylamine, the drug may increase pineal gland nat activity by inhibiting ne reuptake into the presynaptic nerve terminal, thereby increasing the amount of the neurotransmitter available to stimulate pinealocyte beta-noradrenoceptors. |
1989-06-02 |
2023-08-11 |
rat |
| D D Schwartz, D C Eikenbur. Acute epinephrine treatment fails to facilitate stimulus-induced neurotransmitter overflow in the isolated perfused rat kidney. The Journal of pharmacology and experimental therapeutics. vol 249. issue 1. 1989-06-01. PMID:2565387. |
we conclude that the dominance of prejunctional alpha adrenoceptors in the rat kidney results in the inability of epinephrine to produce beta adrenoceptor-mediated facilitation of neurotransmitter overflow even when it is incorporated into renal neurotransmitter stores and coreleased with endogenous norepinephrine upon nerve stimulation. |
1989-06-01 |
2023-08-11 |
rat |
| E M Frohman, T C Frohman, B Vayuvegula, S Gupta, S van den Noor. Vasoactive intestinal polypeptide inhibits the expression of the MHC class II antigens on astrocytes. Journal of the neurological sciences. vol 88. issue 1-3. 1989-03-29. PMID:3265718. |
our results showed that only norepinephrine (ne), a major brain neurotransmitter, and vip, a ubiquitous brain peptide, have the ability to inhibit ia expression on lewis rat astrocyte cultures. |
1989-03-29 |
2023-08-11 |
rat |
| H B Daniell, J G Webb, T Walle, J E Oatis, T E Gaffne. Inhibitors of prostaglandin synthesis reverse the effects of chronic beta-receptor blockade to attenuate adrenergic neurovascular transmission in dogs. Journal of cardiovascular pharmacology. vol 12. issue 3. 1989-03-03. PMID:2464102. |
the vasoconstrictor response to intraarterial phenylephrine was not significantly altered by chronic propranolol treatment, and measurement of norepinephrine overflow during sympathetic nerve stimulation failed to reveal any difference in neurotransmitter release between control- and propranolol-treated dogs. |
1989-03-03 |
2023-08-11 |
Not clear |
| P K Stanton, R S Jones, I Mody, U Heineman. Epileptiform activity induced by lowering extracellular [Mg2+] in combined hippocampal-entorhinal cortex slices: modulation by receptors for norepinephrine and N-methyl-D-aspartate. Epilepsy research. vol 1. issue 1. 1989-01-25. PMID:2904361. |
the neurotransmitter norepinephrine (ne), which has previously been shown to modulate long-term potentiation in the dg, was found to exhibit differential modulation of epileptiform activity in the ec and dg. |
1989-01-25 |
2023-08-11 |
Not clear |
| R Hellweg, C E Bandtlow, R Heumann, S Korschin. Nerve growth factor synthesis in cultured rat iris: modulation by endogenous transmitter substances. Experimental cell research. vol 179. issue 1. 1988-11-23. PMID:2844567. |
however, the sympathetic neurotransmitter norepinephrine (ne) decreased both ngf and its mrna levels specifically in a dose-dependent manner (0.01-1 mm) to a minimum of about 25% of control. |
1988-11-23 |
2023-08-11 |
rat |
| K Szemeredi, G Bagdy, R Stull, H R Keiser, I J Kopin, D S Goldstei. Sympathoadrenomedullary hyper-responsiveness to yohimbine in juvenile spontaneously hypertensive rats. Life sciences. vol 43. issue 13. 1988-11-09. PMID:3172973. |
we examined responses of arterial plasma levels of the sympathetic neurotransmitter, norepinephrine (ne), of the adrenomedullary hormone, epinephrine (e), and of the intraneuronal ne metabolite, dihydroxyphenylglycol (dhpg), after intravenous administration of the alpha-2 adrenoceptor antagonist, yohimbine, in conscious, freely-moving juvenile (4-week old) or mature (12-week old) rats with spontaneous hypertension (shrs) and their normotensive wistar-kyoto (wky) controls. |
1988-11-09 |
2023-08-11 |
rat |
| A H Laube. Atropine sulfate modulates estrogen binding by female, but not male, rat hypothalamus. Brain research bulletin. vol 20. issue 2. 1988-06-24. PMID:3370509. |
studies have shown that pharmacological manipulation of the dopamine, norepinephrine and muscarinic cholinergic neurotransmitter systems modulates the number of neural estrogen binding sites. |
1988-06-24 |
2023-08-11 |
rat |
| S Weiss, B H Schmidt, M Sebben, D E Kemp, J Bockaert, F Sladecze. Neurotransmitter-induced inositol phosphate formation in neurons in primary culture. Journal of neurochemistry. vol 50. issue 5. 1988-06-02. PMID:2452234. |
although the glutamate response appears to be mediated exclusively by direct interaction with the neurotransmitter receptors, responses to carbachol, norepinephrine, and neurotensin were partially or completely blocked by tetrodotoxin. |
1988-06-02 |
2023-08-11 |
Not clear |
| G Helm, R Ekman, C Owma. Cyclic fluctuations of vasoactive intestinal polypeptide measured radioimmunologically in various regions of the human fallopian tube. International journal of fertility. vol 32. issue 6. 1988-02-20. PMID:2891636. |
since there are no major fluctuations in the water content of the tubal tissues in the three phases, the observed changes in vip levels represent real fluctuations at the neural level in a manner similar to that previously shown for the neurotransmitter norepinephrine. |
1988-02-20 |
2023-08-11 |
human |
| D S Goldstein, G Eisenhofer, R Stull, C J Folio, H R Keiser, I J Kopi. Plasma dihydroxyphenylglycol and the intraneuronal disposition of norepinephrine in humans. The Journal of clinical investigation. vol 81. issue 1. 1988-02-09. PMID:3335637. |
we examined plasma levels of the sympathetic neurotransmitter norepinephrine (ne) and its deaminated metabolite dihydroxyphenylglycol (dhpg) during supine rest in healthy human subjects and in sympathectomized patients, during physiological (tilt) or pharmacological (yohimbine, clonidine) manipulations known to affect sympathetically mediated ne release, during blockade of neuronal uptake of ne (uptake-1) using desipramine, and during intravenous infusion of ne. |
1988-02-09 |
2023-08-11 |
human |
| E Richelso. Pharmacology of antidepressants. Psychopathology. vol 20 Suppl 1. 1988-02-05. PMID:2892225. |
antidepressant drugs alter neurotransmitter effects at nerve synapses, probably by blocking norepinephrine and serotonin reuptake, and blockade of neurotransmitter receptor sites - primarily the histamine h1 receptor, the muscarinic receptor, and the alpha-1-adrenoceptor. |
1988-02-05 |
2023-08-11 |
Not clear |
| C J Pirola, A Scheucher, M S Balda, S M Dabsys, S Finkielman, V E Nahmo. Serotonin mediates cardiovascular responses to acetylcholine, bradykinin, angiotensin II and norepinephrine in the lateral septal area of the rat brain. Neuropharmacology. vol 26. issue 6. 1987-07-29. PMID:2885773. |
these results suggest that the effects of acetylcholine, bradykinin and partially of angiotensin ii, depend on the release of norepinephrine and the actions of this neurotransmitter in turn depend on the integrity of the serotonergic system in the lateral septal area. |
1987-07-29 |
2023-08-11 |
rat |