| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Baoyu Shen, Dongxian Zhang, Xiaofeng Zeng, Lina Guan, Genmeng Yang, Liu Liu, Jian Huang, Yuanyuan Li, Shijun Hong, Lihua L. Cannabidiol inhibits methamphetamine-induced dopamine release via modulation of the DRD1-MeCP2-BDNF-TrkB signaling pathway. Psychopharmacology. 2022-01-08. PMID:34997862. |
cannabidiol inhibits methamphetamine-induced dopamine release via modulation of the drd1-mecp2-bdnf-trkb signaling pathway. |
2022-01-08 |
2023-08-13 |
Not clear |
| Katina C Calakos, Heather Liu, Yihuan Lu, Jon Mikael Anderson, David Matuskey, Nabeel Nabulsi, Yunpeng Ye, Patrick D Skosnik, Deepak Cyril D'Souza, Evan D Morris, Kelly P Cosgrove, Ansel T Hillme. Assessment of transient dopamine responses to smoked cannabis. Drug and alcohol dependence. vol 227. 2021-10-21. PMID:34399137. |
assessment of transient dopamine responses to smoked cannabis. |
2021-10-21 |
2023-08-13 |
Not clear |
| Kiana Nouri, Mahsa Anooshe, Saeideh Karimi-Haghighi, Zahra Mousavi, Abbas Haghparas. Involvement of Hippocampal D1-Like Dopamine Receptors in the Inhibitory Effect of Cannabidiol on Acquisition and Expression of Methamphetamine-Induced Conditioned Place Preference. Neurochemical research. vol 46. issue 8. 2021-10-18. PMID:33993443. |
involvement of hippocampal d1-like dopamine receptors in the inhibitory effect of cannabidiol on acquisition and expression of methamphetamine-induced conditioned place preference. |
2021-10-18 |
2023-08-13 |
rat |
| Amir Arash Hassanlou, Shole Jamali, Kimia RayatSanati, Zahra Mousavi, Abbas Haghparas. Cannabidiol modulates the METH-induced conditioned place preference through D2-like dopamine receptors in the hippocampal CA1 region. Brain research bulletin. vol 172. 2021-10-07. PMID:33862125. |
cannabidiol modulates the meth-induced conditioned place preference through d2-like dopamine receptors in the hippocampal ca1 region. |
2021-10-07 |
2023-08-13 |
rat |
| Amir Arash Hassanlou, Shole Jamali, Kimia RayatSanati, Zahra Mousavi, Abbas Haghparas. Cannabidiol modulates the METH-induced conditioned place preference through D2-like dopamine receptors in the hippocampal CA1 region. Brain research bulletin. vol 172. 2021-10-07. PMID:33862125. |
cannabidiol (cbd) has been shown to reduce the effects of meth through different mechanisms such as increasing the ecs activity, regulating emotional memory in the ventral hippocampus through d2-like dopamine receptors, and decreasing the mesolimbic dopaminergic activity. |
2021-10-07 |
2023-08-13 |
rat |
| Amir Arash Hassanlou, Shole Jamali, Kimia RayatSanati, Zahra Mousavi, Abbas Haghparas. Cannabidiol modulates the METH-induced conditioned place preference through D2-like dopamine receptors in the hippocampal CA1 region. Brain research bulletin. vol 172. 2021-10-07. PMID:33862125. |
the present study tried to find out the role of hippocampal ca1 d2-like dopamine receptors (d2r) in the effects of cannabidiol on the acquisition and expression of meth-induced conditioned place preference (meth-cpp) in rats by using microinjection of sulpiride as a d2r antagonist. |
2021-10-07 |
2023-08-13 |
rat |
| Anna Brancato, Valentina Castelli, Gianluca Lavanco, Giuseppe Tringali, Vincenzo Micale, Martin Kuchar, Cesare D'Amico, Giuseppe Pizzolanti, Salvatore Feo, Carla Cannizzar. Binge-like Alcohol Exposure in Adolescence: Behavioural, Neuroendocrine and Molecular Evidence of Abnormal Neuroplasticity… and Return. Biomedicines. vol 9. issue 9. 2021-10-01. PMID:34572345. |
notably, subchronic cannabidiol, during withdrawal, attenuates social- and novelty-induced aversion and passive stress-coping and rectifies the hyper-responsive stress axis and nac dopamine and glutamate-related neuroplasticity. |
2021-10-01 |
2023-08-13 |
rat |
| Ludovic Polli, Raymund Schwan, Eliane Albuisson, Laura Malbos, Karine Angioi-Duprez, Vincent Laprevote, Thomas Schwitze. Oscillatory potentials abnormalities in regular cannabis users: Amacrine cells dysfunction as a marker of central dopaminergic modulation. Progress in neuro-psychopharmacology & biological psychiatry. vol 108. 2021-09-02. PMID:32860840. |
regular cannabis use induces a decreased capacity for dopamine synthesis in the brain. |
2021-09-02 |
2023-08-13 |
Not clear |
| J G Ramaekers, N L Mason, E L Theunisse. Blunted highs: Pharmacodynamic and behavioral models of cannabis tolerance. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 36. 2021-08-10. PMID:32014378. |
such neuroadaptions are absent in occasional users, who show strong increments of dopamine and glutamate levels in the striatum, a loss of functional connectivity within the mesolimbic circuit and neurocognitive impairments when exposed to cannabis. |
2021-08-10 |
2023-08-13 |
human |
| Christin Schifani, Jens Pruessner, Huai-Hsuan Tseng, Naren Rao, Abanti Tagore, Alan A Wilson, Sylvain Houle, Pablo M Rusjan, Romina Mizrah. Stress-induced cortical dopamine response is altered in subjects at clinical high risk for psychosis using cannabis. Addiction biology. vol 25. issue 4. 2021-06-28. PMID:31389139. |
stress-induced cortical dopamine response is altered in subjects at clinical high risk for psychosis using cannabis. |
2021-06-28 |
2023-08-13 |
human |
| Christin Schifani, Jens Pruessner, Huai-Hsuan Tseng, Naren Rao, Abanti Tagore, Alan A Wilson, Sylvain Houle, Pablo M Rusjan, Romina Mizrah. Stress-induced cortical dopamine response is altered in subjects at clinical high risk for psychosis using cannabis. Addiction biology. vol 25. issue 4. 2021-06-28. PMID:31389139. |
we have previously shown that subjects at clinical high risk for psychosis (chr) exhibit a higher striatal dopamine response to stress compared with healthy volunteers (hv), with chronic cannabis use blunting this response. |
2021-06-28 |
2023-08-13 |
human |
| Kenneth Blum, Joseph Morgan, Jean Lud Cadet, David Baron, Paul R Carney, Jag Khalsa, Rajendra D Badgaiyan, Mark S Gol. Psychoactive Drugs Like Cannabis -Induce Hypodopaminergic Anhedonia and Neuropsychological Dysfunction in Humans: Putative Induction of Dopamine Homeostasis via Coupling of Genetic Addiction Risk Severity (GARS) testing and Precision Pro-dopamine Regulation (KB220). Neurology (E-Cronicon). vol 13. issue 4. 2021-06-06. PMID:34085060. |
psychoactive drugs like cannabis -induce hypodopaminergic anhedonia and neuropsychological dysfunction in humans: putative induction of dopamine homeostasis via coupling of genetic addiction risk severity (gars) testing and precision pro-dopamine regulation (kb220). |
2021-06-06 |
2023-08-13 |
Not clear |
| b' Anna Grzywacz, Wojciech Barczak, Jolanta Chmielowiec, Krzysztof Chmielowiec, Aleksandra Suchanecka, Grzegorz Trybek, Jolanta Masiak, Pawe\\xc5\\x82 Jagielski, Katarzyna Grocholewicz, Blazej Rubi\\xc5\\x9. Contribution of Dopamine Transporter Gene Methylation Status to Cannabis Dependency. Brain sciences. vol 10. issue 6. 2021-06-04. PMID:32586035.' |
contribution of dopamine transporter gene methylation status to cannabis dependency. |
2021-06-04 |
2023-08-13 |
Not clear |
| Hye Bin Yoo, Jennifer DiMuzio, Francesca M Filbe. Interaction of Cannabis Use and Aging: From Molecule to Mind. Journal of dual diagnosis. vol 16. issue 1. 2021-05-21. PMID:31570066. |
specifically, the effects of cannabis and aging converge on overlapping networks in the endocannabinoid, opioid, and dopamine systems that may affect functional decline particularly in the hippocampus and prefrontal cortex, which are critical areas for memory and executive functioning. |
2021-05-21 |
2023-08-13 |
Not clear |
| Marco Colizzi, Nathalie Weltens, Philip McGuire, David Lythgoe, Steve Williams, Lukas Van Oudenhove, Sagnik Bhattacharyy. Delta-9-tetrahydrocannabinol increases striatal glutamate levels in healthy individuals: implications for psychosis. Molecular psychiatry. vol 25. issue 12. 2021-05-14. PMID:30770892. |
while some evidence suggests altered striatal dopamine may underlie the association, direct evidence that cannabis use affects either acute or chronic striatal dopamine is inconclusive. |
2021-05-14 |
2023-08-13 |
human |
| Marco Colizzi, Nathalie Weltens, Philip McGuire, David Lythgoe, Steve Williams, Lukas Van Oudenhove, Sagnik Bhattacharyy. Delta-9-tetrahydrocannabinol increases striatal glutamate levels in healthy individuals: implications for psychosis. Molecular psychiatry. vol 25. issue 12. 2021-05-14. PMID:30770892. |
in contrast, pre-clinical research suggests that cannabis may affect dopamine via modulation of glutamate signaling. |
2021-05-14 |
2023-08-13 |
human |
| Kenneth Blum, Jag Khalsa, Jean Lud Cadet, David Baron, Abdalla Bowirrat, Brent Boyett, Lisa Lott, Raymond Brewer, Marjorie Gondré-Lewis, Gregory Bunt, Shan Kazmi, Mark S Gol. Cannabis-Induced Hypodopaminergic Anhedonia and Cognitive Decline in Humans: Embracing Putative Induction of Dopamine Homeostasis. Frontiers in psychiatry. vol 12. 2021-04-21. PMID:33868044. |
research shows that exposure to cannabis is associated with hypodopaminergic anhedonia (depression), cognitive decline, poor memory, inattention, impaired learning performance, reduced dopamine brain response-associated emotionality, and increased addiction severity in young adults. |
2021-04-21 |
2023-08-13 |
Not clear |
| Kenneth Blum, Jag Khalsa, Jean Lud Cadet, David Baron, Abdalla Bowirrat, Brent Boyett, Lisa Lott, Raymond Brewer, Marjorie Gondré-Lewis, Gregory Bunt, Shan Kazmi, Mark S Gol. Cannabis-Induced Hypodopaminergic Anhedonia and Cognitive Decline in Humans: Embracing Putative Induction of Dopamine Homeostasis. Frontiers in psychiatry. vol 12. 2021-04-21. PMID:33868044. |
preliminary research suggests that it is possible to induce 'dopamine homeostasis,' that is, restore dopamine function with dopamine upregulation with the proposed compound and normalize behavior in chronic cannabis users with cannabis-induced hypodopaminergic anhedonia (depression) and cognitive decline. |
2021-04-21 |
2023-08-13 |
Not clear |
| Y Daniju, M G Bossong, K Brandt, P Alle. Do the effects of cannabis on the hippocampus and striatum increase risk for psychosis? Neuroscience and biobehavioral reviews. vol 112. 2021-03-26. PMID:32057817. |
we use an established preclinical model of psychosis, the methylazoxymethanol acetate (mam) rodent model, as a framework to examine if psychosis risk in some cannabis users is mediated by the effects of cannabis on the hippocampus, and this region's role in the regulation of mesolimbic dopamine. |
2021-03-26 |
2023-08-13 |
Not clear |
| Tibor Stark, Martina Di Bartolomeo, Roberta Di Marco, Eva Drazanova, Chiara Bianca Maria Platania, Fabio Arturo Iannotti, Jana Ruda-Kucerova, Claudio D'Addario, Lucie Kratka, Vladimir Pekarik, Fabiana Piscitelli, Zuzana Babinska, Julia Fedotova, Giovanni Giurdanella, Salvatore Salomone, Alexandra Sulcova, Claudio Bucolo, Carsten T Wotjak, Zenon Starcuk, Filippo Drago, Raphael Mechoulam, Vincenzo Di Marzo, Vincenzo Mical. Altered dopamine D3 receptor gene expression in MAM model of schizophrenia is reversed by peripubertal cannabidiol treatment. Biochemical pharmacology. vol 177. 2020-12-07. PMID:32360362. |
altered dopamine d3 receptor gene expression in mam model of schizophrenia is reversed by peripubertal cannabidiol treatment. |
2020-12-07 |
2023-08-13 |
rat |