Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
L Liu, Q Zhao, J Huang, S Le. Cadmium-Induced Hepatotoxicity in Mice - Prophylactic Supplementation of Quercetin Exerts Hepatoprotective Effect by Modulating PI3K/Akt/NF-kappaB Signaling Pathway. Physiological research. vol 73. issue 5. 2024-11-12. PMID:39530906. |
liver function markers like alanine transaminase (alt), aspartate transaminase (ast), alkaline phosphatase (alp), and lactate dehydrogenase (ldh) were significantly reduced in quercetin treatment in cd-induced mice. |
2024-11-12 |
2024-11-17 |
mouse |
Yanlong Li, Zhikang Ye, Xingyu Ran, Jintian Luo, Hui Li, Peng Zhou, Si Shen, Jing L. Association between depression and liver function biomarkers among US cancer survivors in NHANES 2005-2020. Scientific reports. vol 14. issue 1. 2024-11-11. PMID:39528812. |
after adjusted with age, gender, race, marital status, education level, family income-to-poverty ratio, and number of cancer types, 8 biomarkers demonstrated positive correlations with depression in cancer survivors, included alanine aminotransferase (alt, or = 1.007, 95% ci: 1.000 to 1.013), alkaline phosphatase (alp, 1.006 [1.002, 1.010]), gamma glutamyl transferase (ggt, 1.004 [1.001, 1.007]), lactate dehydrogenase (ldh, 1.004 [1.000, 1.009]), total protein (tp, 1.040 [1.009, 1.072]), globulin (glb, 1.060 [1.030, 1.091]), total cholesterol (tc) to high-density lipoprotein cholesterol (hdl-c) ratio (1.162 [1.050, 1.286]), and low-density lipoprotein cholesterol (ldl-c) to hdl-c ratio (1.243 [1.012, 1.526]); while 4 other biomarkers exhibited negative correlations, included hdl-c (0.988 [0.980, 0.997]), total bilirubin (tbi, 0.501 [0.284, 0.883]), aspartate aminotransferase (ast) to alt ratio (0.588 [0.351, 0.986]), albumin (alb) to glb ratio (0.384 [0.229, 0.642]). |
2024-11-11 |
2024-11-17 |
Not clear |
Mohamed E Abd El-Hack, Ahmed K Aldhalmi, Adel I Attia, Zenat A Ibrahem, Garsa Alshehry, Mohamed Loutfi, Ahmed A Elolimy, Mohamed S El-Khol. Effects of including different levels of equal mix of soybean and flaxseed oils in Japanese quail diets on the growth, carcass quality, and blood biomarkers. Poultry science. vol 103. issue 12. 2024-11-09. PMID:39520756. |
quails fed oil-supplemented diets showed lower serum alanine aminotransferase (alt), aspartate aminotransferase (ast), and creatinine levels, while urea and uric acid were significantly affected. |
2024-11-09 |
2024-11-17 |
Not clear |
Jing Sun, Xiuli Jin, Yiling L. OTUD7B inhibited hepatic injury from NAFLD by inhibiting K48-linked ubiquitination and degradation of β-catenin. Biochimica et biophysica acta. Molecular basis of disease. vol 1871. issue 1. 2024-11-09. PMID:39520879. |
adenoviral overexpression of otud7b in mice resulted in reduced body weight and liver injury, with decreased serum aminotransferase (alt) and aspartate aminotransferase (ast) levels. |
2024-11-09 |
2024-11-17 |
mouse |
S R Mule, Dilip Kumar Singh, Patekar Prakash, Swapnil Ananda Narsale, M D Aklakur, Parimal Sardar, Gouranga Biswas, Sujata Sahoo, Manish Jayant, Samikshya Mishr. Effect of dietary Anabaena supplementation on nutrient utilization, metabolism and oxidative stress response in Catla catla fingerlings. Scientific reports. vol 14. issue 1. 2024-11-09. PMID:39521801. |
there were no significant differences (p > 0.05) observed in serum total protein, albumin/globulin (a/g) ratio, aspartate aminotransferase (ast), and alanine aminotransferase (alt) activities among the experimental groups. |
2024-11-09 |
2024-11-17 |
cat |
Hui Zhao, Huihui Tao, Jifeng Fu, Weilong Hou, Chunxiao Hu, Yafeng Liu, Xuansheng Ding, Dong Hu, Yong Da. Cross-sectional analysis of dyslipidemia risk in coal mine workers: from epidemiology to animal models. Scientific reports. vol 14. issue 1. 2024-11-06. PMID:39505893. |
in the mouse model of coal dust exposure, significant coal dust deposition was observed in the lungs and livers of the mice, accompanied by elevated levels of total cholesterol (tc), alanine transaminase (alt), aspartate transaminase (ast), and low-density lipoprotein cholesterol (ldl-c). conclusion exposure to coal dust significantly increases the risk of developing dyslipidemia, and this positive correlation exists in different populations, particularly with increasing years of work, resulting in a higher risk. |
2024-11-06 |
2024-11-09 |
mouse |
Merve Aydın, Evren Köse, Elif Taşlıdere Karaca, Kevser Tanbek, Süleyman Sanda. Investigation of the protective effect of Heliyon. vol 10. issue 20. 2024-11-04. PMID:39492916. |
alanine aminotransferase (alt), aspartate aminotransferase (ast), and total bilirubin (tb) values were measured from serum samples. |
2024-11-04 |
2024-11-06 |
rat |
Inshya Desai, Shivani K Modi, Abdul Subha. A Case of Statin-Induced Necrotizing Autoimmune Myopathy. Cureus. vol 16. issue 10. 2024-11-04. PMID:39493067. |
on labs, her aspartate transaminase (ast) and alanine transaminase (alt) were both elevated at 344 and 244, respectively. |
2024-11-04 |
2024-11-06 |
Not clear |
Gailing Hao, Wenjin Geng, Chunzhen Li, Quanheng Li, Nan Zhang, Lian Jian. Critical risk factors analysis of infection-associated hemophagocytic lymphohistiocytosis in children. Annals of hematology. 2024-11-04. PMID:39495283. |
alanine aminotransferase (alt), aspartate aminotransferase (ast), lactate dehydrogenase (ldh), gamma-glutamyl transferase (ggt), d-dimer (dd), and triglycerides (tg) were significantly higher in the critical group, while albumin (alb) was significantly lower, showing statistical significance (p < 0.05). |
2024-11-04 |
2024-11-06 |
Not clear |
Yitong Bian, Huijuan Kou, Zhen Jia, Qing Cui, Peng Wu, Juan Ma, Xueping Ma, Ping Ji. Association between aspartate aminotransferase to alanine aminotransferase ratio and mortality in critically ill patients with congestive heart failure. Scientific reports. vol 14. issue 1. 2024-11-02. PMID:39487164. |
the aspartate aminotransferase (ast) to alanine aminotransferase (alt) ratio (ast/alt), has also been reported as a risk factor of cardiovascular diseases. |
2024-11-02 |
2024-11-05 |
human |
Guangtian Ma, Habtamu Ayalew, Tahir Mahmood, Yves Mercier, Jing Wang, Jing Lin, Shugeng Wu, Kai Qiu, Guanghai Qi, Haijun Zhan. Methionine and vitamin E supplementation improve production performance, antioxidant potential, and liver health in aged laying hens. Poultry science. vol 103. issue 12. 2024-11-02. PMID:39488017. |
oh-met at 0.95 and dl-met at 0.90 tsaa: lys ratio showed higher cat and lower aspartate aminotransferase (ast) activities. |
2024-11-02 |
2024-11-05 |
cat |
Ahmed Hussein, Kateri L Schoettinger, Jourdan Hydol-Smith, Kristopher Fisher, Rachel M Kirven, Benjamin H Kaffenberger, Abraham M Korma. Vancomycin-associated DRESS demonstrates delay in AST abnormalities. Archives of dermatological research. vol 316. issue 10. 2024-11-01. PMID:39485591. |
our study aims to investigate associations between medication class and peak serum laboratory values using simple linear regression (absolute eosinophils, creatinine, alanine aminotransferase [alt] and aspartate aminotransferase [ast]). |
2024-11-01 |
2024-11-04 |
Not clear |
Rui Zheng, Defei Meng, Ninghao Hao, Haipeng Wang, Wenli Peng, Li Wang, Yong We. Yak IFNβ-3 enhances macrophage activity and attenuates Klebsiella pneumoniae infection. International immunopharmacology. vol 143. issue Pt 3. 2024-11-01. PMID:39486177. |
the contents of aspartate aminotransferase (ast) and lactate dehydrogenase (ldh) in the serum of mice after klebsiella pneumoniae infection were reduced by ifnβ3 protein (p < 0.05). |
2024-11-01 |
2024-11-05 |
mouse |
Miguel Ángel Villasís-Keever, Jessie Nallely Zurita-Cruz, Karla Nava-Sánchez, Aly Sugei Barradas-Vázquez, Ana Laura López-Beltrán, Mireya Elizabeth Espíritu-Díaz, Martha Alicia Delgadillo-Ruan. [Comparison of serum uric acid and liver enzyme levels in adolescents with obesity and with metabolic syndrome]. Nutricion hospitalaria. vol 41. issue 5. 2024-10-31. PMID:38896119. |
somatometric data, serum insulin, lipid profile, uric acid levels and liver enzymes (aspartate aminotransferase [ast], alanine aminotransferase [alt] and gamma-glutamyl transferase [ggt]) were analyzed. |
2024-10-31 |
2024-11-02 |
Not clear |
Xun Li, Haipeng Yan, Zili Cai, Xiao Li, Longlong Xie, Ting Luo, Xiangyu Wang, Yufan Yang, Ling Gong, Minghui Tang, Xinping Zhang, Jiaotian Huang, Xiulan Lu, Zhenghui Xia. Pre-diagnostic trajectory of pediatric hemophagocytic lymphohistiocytosis: observations from hematological and hepatic parameters. Annals of hematology. 2024-10-28. PMID:39463183. |
over 80% of pediatric hlh patients presented abnormal laboratory results for aspartate aminotransferase (ast), triglycerides, lactate dehydrogenase (ldh), and hemoglobin at admission. |
2024-10-28 |
2024-10-30 |
Not clear |
b' Dalibor Mihajlovi\\xc4\\x87, \\xc4\\x90or\\xc4\\x91e \\xc4\\x90ukanovi\\xc4\\x87, Milica Gaji\\xc4\\x87 Boji\\xc4\\x87, Sanja Jovi\\xc4\\x8di\\xc4\\x87, Neboj\\xc5\\xa1a Mandi\\xc4\\x87-Kova\\xc4\\x8devi\\xc4\\x87, Sne\\xc5\\xbeana Uletilovi\\xc4\\x87, \\xc5\\xbdana M Maksimovi\\xc4\\x87, Neboj\\xc5\\xa1a Pavlovi\\xc4\\x87, Boris Doj\\xc4\\x8dinovi\\xc4\\x87, Sergey Bolevich, Momir Mikov, Ranko \\xc5\\xa0krbi\\xc4\\x87, Nada Banjac, Velibor Vasovi\\xc4\\x8. Cardioprotective Effects of Ursodeoxycholic Acid in Isoprenaline-Induced Myocardial Injury in Rats. Biomolecules. vol 14. issue 10. 2024-10-26. PMID:39456147.' |
udca pre-treatment significantly reduced values of high-sensitivity troponin i (hstni) and aspartate aminotransferase (ast) cardiac markers ( |
2024-10-26 |
2024-10-29 |
rat |
b' Sonia L Espindola, Jessica Fay, Graciela M Carballo, Mat\\xc3\\xadas J Pereson, Natalia Aloisi, Mar\\xc3\\xada Noel Badano, Juli\\xc3\\xa1n Ferreras, Carina Arg\\xc3\\xbcelles, Sim\\xc3\\xb3n Pezzarini, Roberto Chuit, Marcos Miretti, Federico A Di Lello, Patricia Bar\\xc3\\xa. Secondary Dengue Infection Elicits Earlier Elevations in IL-6 and IL-10 Levels. International journal of molecular sciences. vol 25. issue 20. 2024-10-26. PMID:39457019.' |
thrombocytopenia and elevated aspartate transaminase (ast) levels were associated with phase ii, secondary infections, and hospitalization. |
2024-10-26 |
2024-10-29 |
Not clear |
Young-Bin Yu, Ju-Wook Lee, A-Hyun Jo, Young Jae Choi, Cheol Young Choi, Ju-Chan Kang, Jun-Hwan Ki. Toxic Effects of Cadmium Exposure on Hematological and Plasma Biochemical Parameters in Fish: A Review. Toxics. vol 12. issue 10. 2024-10-26. PMID:39453119. |
plasma biochemical parameters, including calcium, magnesium, glucose, cholesterol, total protein, and liver enzymes such as aspartate aminotransferase (ast), alanine aminotransferase (alt), and alkaline phosphatase (alp), are crucial for understanding ionic balance, metabolic regulation, and organ function, especially in fish exposed to cd. |
2024-10-26 |
2024-10-28 |
Not clear |
Karol Żmudka, Jerzy Jaroszewicz, Dorota Zarębska-Michaluk, Magdalena Rogalska, Piotr Czupryna, Marta Rorat, Dorota Kozielewicz, Jadwiga Maciukajć, Sławomir Kiciak, Magdalena Krępa, Ewa Dutkiewicz, Michał Stojko, Aleksandra Spychał, Przemysław Ciechanowski, Beata Bolewska, Regina Podlasin, Robert Flisia. Association between Liver Damage and Disease Progression Markers with Mortality Risk and Mechanical Ventilation in Hospitalized COVID-19 Patients: A Nationwide Retrospective SARSTer Study. Viruses. vol 16. issue 10. 2024-10-26. PMID:39459864. |
(1) background: liver damage is an important component of acute covid-19, and the advancement of preexisting liver disease is associated with a worse prognosis; (2) methods: a nationwide retrospective study including 7444 patients aimed to evaluate levels of selected markers of liver damage and disease advancement and their association with mortality and mechanical ventilation (mv); (3) results: elevation of the following markers in multivariate models were associated with increased odds of mortality: alanine transaminase (alt), aspartate transaminase (ast), gamma-glutamyltransferase (ggt), lactate dehydrogenase (ldh), fibrosis-4 score (fib-4), ast-to-platelet ratio index (apri), and decreased levels of platelet count (plt). |
2024-10-26 |
2024-10-29 |
Not clear |
Jingru Song, Yanping Huang, Lu Liu, Dengcheng Hui, Zheng Wang, Dong Xie, Yulang Jiang, Hongyan Cao, Yancheng Dai, Guan Ye, Shibing Su, Mingmei Zhou, Qin Zhang, Mingyu Su. Integrated metabolomics and network pharmacology to explore the clinical efficacy and mechanism of Yinchenhao decoction combined with nucleoside analogues on chronic hepatitis B. Journal of pharmaceutical and biomedical analysis. vol 253. 2024-10-26. PMID:39461066. |
it revealed that nas plus ychd could significantly improve alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels, increase hbv-dna negative rate (p<0.05), reduce the levels of inflammatory factors and lsm (both p<0.05), regulate lipids (p<0.05), and improve the symptoms of traditional chinese medicine (tcm) (p<0.05) in chb patients. |
2024-10-26 |
2024-10-30 |
Not clear |