| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ting Linghu, Yao Gao, Aiping Li, Biyun Shi, Junsheng Tian, Xuemei Qi. A unique insight for energy metabolism disorders in depression based on chronic unpredictable mild stress rats using stable isotope-resolved metabolomics. Journal of pharmaceutical and biomedical analysis. vol 191. 2021-06-17. PMID:32927418. |
pyruvate carboxylase (pc), pyruvate dehydrogenase (pdh), aspartate aminotransferase (ast) and phosphoenolpyruvate carboxykinase (pepc) may be the new targets for depression. |
2021-06-17 |
2023-08-13 |
human |
| Jerry R Nedelman, David H Salinger, Vishak Subramoney, Rob Woolson, Karen Wade, Mengchun Li, Daniel Everitt, Carl M Mendel, Mel Spigelma. An Exposure-Response Perspective on the Clinical Dose of Pretomanid. Antimicrobial agents and chemotherapy. vol 65. issue 1. 2021-06-17. PMID:33077660. |
no significant e-r relationships were found for the single preferred terms nausea, alanine aminotransferase (alt) increased, aspartate aminotransferase (ast) increased, and headache and for the collections hepatic disorders, transaminases increased, skin and subcutaneous tissue disorders, and headache. |
2021-06-17 |
2023-08-13 |
Not clear |
| Hilal Ahmad Khan, Tariq Munir, Junaid Ali Khan, Al-Hafiza Shafia Tehseen Gul, Muhammad Zishan Ahmad, Muhammad Aamir Aslam, Muhammad Numman Umar, Muhammad Imran Arsha. IL-33 ameliorates liver injury and inflammation in Poly I:C and Concanavalin-A induced acute hepatitis. Microbial pathogenesis. vol 150. 2021-06-17. PMID:33383149. |
the gross lesions, level of serum aspartate aminotransferase (ast), alanine aminotransferase (alt), histopathology (h&e staining) and levels of ifnγ and tnfα were measured by elisa. |
2021-06-17 |
2023-08-13 |
mouse |
| Meng Zhang, Yuting Fu, Yuhao Chen, Yuze Ma, Zhixin Guo, Yanfeng Wang, Huifang Hao, Quan Fu, Zhigang Wan. Inhibition of the mTORC1/NF- BioMed research international. vol 2021. 2021-06-17. PMID:33542926. |
the transamination, oxidative deamination, and decarboxylation processes that occur during amino acid catabolism are catalyzed by specific enzymes, including aspartate aminotransferase (ast), glutamate dehydrogenase (gdh), glutamic acid decarboxylase (gad), and ornithine decarboxylase (odc); however, the overall molecular mechanisms through which amino acid catabolism occurs remain largely unknown. |
2021-06-17 |
2023-08-13 |
Not clear |
| Prakash Khadka, Shubhra Sinha, Ian G Tucker, Jack Dummer, Philip C Hill, Rajesh Katare, Shyamal C Da. Studies on the safety and the tissue distribution of inhaled high-dose amorphous and crystalline rifampicin in a rat model. International journal of pharmaceutics. vol 597. 2021-06-17. PMID:33545287. |
serum alanine transaminase (alt) and aspartate aminotransferase (ast) assays were performed to study the hepatic effects. |
2021-06-17 |
2023-08-13 |
rat |
| Ming-Yang Tsai, Wei-Cheng Yang, Chuen-Fu Lin, Chao-Min Wang, Hsien-Yueh Liu, Chen-Si Lin, Jen-Wei Lin, Wei-Li Lin, Tzu-Chun Lin, Pei-Shan Fan, Kuo-Hsiang Hung, Yu-Wen Lu, Geng-Ruei Chan. The Ameliorative Effects of Fucoidan in Thioacetaide-Induced Liver Injury in Mice. Molecules (Basel, Switzerland). vol 26. issue 7. 2021-06-17. PMID:33808318. |
the treated mice showed significantly higher body weights; food intakes; hepatic antioxidative enzymes (catalase, glutathione peroxidase (gpx), and superoxide dismutase (sod)); and a lower serum alanine aminotransferase (alt), aspartate aminotransferase (ast), tumor necrosis factor-α (tnf-α), interleukin-1β (il-1β), and c-reactive protein (crp) levels. |
2021-06-17 |
2023-08-13 |
mouse |
| Rongwei Lei, Chandra Moha. Immunological Biomarkers of COVID-19. Critical reviews in immunology. vol 40. issue 6. 2021-06-17. PMID:33900694. |
multiplex biomarker analyses based on hematological and cytokine changes in combination with biomedical levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), lactate dehydrogenase (ldh), n-terminal prohormone bnp (nt-probnp), serum urea, c-reactive protein (crp), and d-dimer have shown improved diagnostic accuracy for determining disease severity in patients compared with single biomarker analyses. |
2021-06-17 |
2023-08-13 |
Not clear |
| Jeesun Kim, Suk Kyun Hong, Jieun Lim, Jeong-Moo Lee, Jae-Hyung Cho, YoungRok Choi, Nam-Joon Yi, Kwang-Woong Lee, Kyung-Suk Su. Demarcating the Exact Midplane of the Liver Using Indocyanine Green Near-Infrared Fluorescence Imaging During Laparoscopic Donor Hepatectomy. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. vol 27. issue 6. 2021-06-16. PMID:33583130. |
the operation time was shorter (p = 0.002) and postoperative peak aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels were lower (p = 0.031 and p = 0.019, respectively) in the post-icg group than the pre-icg group. |
2021-06-16 |
2023-08-13 |
Not clear |
| Takashi Ikeda, Hiroki Ishihara, Toshio Takagi, Hironori Fukuda, Kazuhiko Yoshida, Junpei Iizuka, Hirohito Kobayashi, Masayoshi Okumi, Hideki Ishida, Tsunenori Kondo, Kazunari Tanab. The De Ritis (Aspartate Transaminase/Alanine Transaminase) Ratio as a Prognosticator in Patients With End-stage Renal Disease-associated Renal Cell Carcinoma. Clinical genitourinary cancer. vol 18. issue 3. 2021-06-14. PMID:31917171. |
the aspartate transaminase (ast)/alanine transaminase (alt) ratio (ie, the de ritis ratio) is associated with prognosis in some types of cancers including renal cell carcinoma (rcc). |
2021-06-14 |
2023-08-13 |
Not clear |
| Hanan El Baz, Zeinab Demerdash, Manal Kamel, Olfat Hammam, Dina Samir Abdelhady, Soheir Mahmoud, Salwa Hassan, Faten Mahmoud, Shimaa Atta, Nermine Magdi Riad, Taghrid Gaafa. Induction of Hepatic Regeneration in an Experimental Model Using Hepatocyte-Differentiated Mesenchymal Stem Cells. Cellular reprogramming. vol 22. issue 3. 2021-06-14. PMID:32243193. |
in experimental model, msc-3d treated group exhibited maximal restoration of liver architecture with absent septal fibrosis and marked improvement of alanine transaminase (alt) and aspartate transaminase (ast), and mild increase in albumin. |
2021-06-14 |
2023-08-13 |
Not clear |
| Yasser Abobakr, Amira F Gad, Hamza S Abou-Elnasr, Gaber M Abdelgalil, Hamdy I Hussein, Shady Seli. Contact toxicity and biochemical impact of metaldehyde against the white garden snail Theba pisana (Müller, 1774). Pest management science. vol 77. issue 7. 2021-06-14. PMID:33683007. |
the biochemical impact of metaldehyde on acetylcholinesterase (ache), aspartate aminotransferase (ast) and alanine aminotransferase (alt), alkaline phosphatase (alp) and glutathione s-transferase (gst) activities and the lipid peroxidation (lpo) level was investigated. |
2021-06-14 |
2023-08-13 |
Not clear |
| Isabel Campos-Varela, Ares Villagrasa, Macarena Simon-Talero, Mar Riveiro-Barciela, Meritxell Ventura-Cots, Lara Aguilera-Castro, Patricia Alvarez-Lopez, Emilie A Nordahl, Adrian Anton, Juan Bañares, Claudia Barber, Ana Barreira-Diaz, Betina Biagetti, Laura Camps-Relats, Andrea Ciudin, Raul Cocera, Cristina Dopazo, Andrea Fernandez, Cesar Jimenez, Maria M Jimenez, Mariona Jofra, Clara Gil, Concepción Gomez-Gavara, Danila Guanozzi, Jorge A Guevara, Beatriz Lobo, Carolina Malagelada, Joan Martinez-Camprecios, Luis Mayorga, Enric Miret, Elizabeth Pando, Ana Pérez-Lopez, Marc Pigrau, Alba Prio, Jesus M Rivera-Esteban, Alba Romero, Stephanie Tasayco, Judit Vidal-Gonzalez, Laura Vidal, Beatriz Minguez, Salvador Augustin, Joan Genesc. The role of liver steatosis as measured with transient elastography and transaminases on hard clinical outcomes in patients with COVID-19. Therapeutic advances in gastroenterology. vol 14. 2021-06-11. PMID:34104210. |
alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels were elevated at admission in 130 patients (35%) and 167 (45%) patients, respectively. |
2021-06-11 |
2023-08-13 |
Not clear |
| Hidetsugu Kawai, Kiyoshi Ando, Dai Maruyama, Kazuhito Yamamoto, Eiji Kiyohara, Yasuhito Terui, Noriko Fukuhara, Tomomitsu Miyagaki, Yoshiki Tokura, Mamiko Sakata-Yanagimoto, Tadahiko Igarashi, Junya Kuroda, Jiro Fujita, Toshiki Uchida, Takayuki Ishikawa, Kentaro Yonekura, Koji Kato, Tadashi Nakanishi, Kenya Nakai, Risa Matsunaga, Kensei Tobina. Phase II study of E7777 in Japanese patients with relapsed/refractory peripheral and cutaneous T-cell lymphoma. Cancer science. vol 112. issue 6. 2021-06-10. PMID:33792128. |
the common adverse events (aes) observed were increased aspartate aminotransferase (ast) / alanine aminotransferase (alt), hypoalbuminemia, lymphopenia, and pyrexia. |
2021-06-10 |
2023-08-13 |
human |
| Vicente E Torres, Arlene B Chapman, Olivier Devuyst, Ron T Gansevoort, Ronald D Perrone, Jennifer Lee, Molly E Hoke, Alvin Estilo, Olga Sergeyev. Multicenter Study of Long-Term Safety of Tolvaptan in Later-Stage Autosomal Dominant Polycystic Kidney Disease. Clinical journal of the American Society of Nephrology : CJASN. vol 16. issue 1. 2021-06-09. PMID:33376102. |
serum alanine aminotransferase (alt) or aspartate aminotransferase (ast) elevations occurred in all three studies. |
2021-06-09 |
2023-08-13 |
Not clear |
| Jessyca Karen Pinheiro, Severino Gonzaga Neto, Ricardo Dias Signoretti, Lara Toledo Henriques, José Maria Cesar Neto, Jovanna Karine Pinheir. Metabolic status of lactating cows given a hepatoprotectant and different feed energy sources. Tropical animal health and production. vol 53. issue 1. 2021-06-08. PMID:33641025. |
ground corn as an energy source yielded higher serum concentrations of glucose, hdl (high-density lipoprotein) cholesterol, and globulins, whereas b-hydroxybutyrate (bhb), non-esterified fatty acids (nefa), total cholesterol, albumin, and aspartate aminotransferase (ast) yielded the highest concentrations in diets containing citrus pulp. |
2021-06-08 |
2023-08-13 |
Not clear |
| Bibek Bakhati, Victoria M Sibi, Armugam P Mekala, Joshua A Ronen, Sai Mungar. What Is Uncommon Can Be Critical: A Case of Quinolone-Induced Acute Liver Failure. Cureus. vol 13. issue 4. 2021-06-08. PMID:34094745. |
following its administration, serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) increased more than 100-fold above the upper limit of normal. |
2021-06-08 |
2023-08-13 |
Not clear |
| Xueliang Qi, Xiangguo Sun, Xuemin Li, Dejin Kong, Luhua Zha. Significance changes in the levels of myocardial enzyme in the child patients with Mycoplasma Pneumoniae Pneumonia. Cellular and molecular biology (Noisy-le-Grand, France). vol 66. issue 6. 2021-06-07. PMID:33040783. |
for this aim, a total of 120 child patients with mpp in the acute phase,120 child patients with mpp in the recovery phase and 120 healthy children were simultaneously enrolled into this study to detect the levels of aspartate aminotransferase (ast), creatine kinase (ck), creatine kinase isoenzyme (ck-mb) and lactic dehydrogenase (ldh) in blood. |
2021-06-07 |
2023-08-13 |
Not clear |
| Chenyang Li, Jiali Chen, Man Zhao, Mengqi Liu, Zhengkai Yue, Lei Liu, Fuchang L. Effect of sodium butyrate on slaughter performance, serum indexes and intestinal barrier of rabbits. Journal of animal physiology and animal nutrition. 2021-06-07. PMID:34096104. |
meanwhile, the content of aspartate aminotransferase (ast) in serum was increased in rabbits fed the sodium butyrate diet. |
2021-06-07 |
2023-08-13 |
rabbit |
| Minah Kim, Yeonju Lee, Jun Sik Yoon, Minjong Lee, So Shin Kye, Sun Woong Kim, Yuri Ch. The FIB-4 Index Is a Useful Predictor for the Development of Hepatocellular Carcinoma in Patients with Coexisting Nonalcoholic Fatty Liver Disease and Chronic Hepatitis B. Cancers. vol 13. issue 10. 2021-06-05. PMID:34064988. |
the fib-4 index, a noninvasive tool (fib-4 index = age × aspartate transaminase (ast)/(platelet count × √alanine aminotransferase (alt)), is a useful assessment for liver fibrosis. |
2021-06-05 |
2023-08-13 |
Not clear |
| Lichun Xiao, Yu Bei, Jian'an Li, Minjie Chen, Youying Zhang, Qi Xian. Preclinical Pharmacokinetics, Tissue Distribution and Primary Safety Evaluation of a Novel Curcumin Analogue H10 Suspension, a Potential 17β Hydroxysteroid Dehydrogenase Type 3 Inhibitor. Chemical & pharmaceutical bulletin. vol 69. issue 1. 2021-06-04. PMID:33087639. |
moreover, h10 showed weak inhibition towards liver cyp3a4, and did not cause significant changes in aspartate transaminase (ast) and alanine transaminase (alt) levels after treated with h10 for continuously 30 d. |
2021-06-04 |
2023-08-13 |
mouse |