| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nagwa I Mohamed, Ghada M Suddek, Dalia H El-Kashe. Molsidomine alleviates acetic acid-induced colitis in rats by reducing oxidative stress, inflammation and apoptosis. International immunopharmacology. vol 99. 2021-09-08. PMID:34330056. |
besides, molsidomine significantly reduced the serum levels of alanine transaminase (alt) (58.7 ± 8.9 & 59.7 ± 8 vs 288.75 ± 31.4 in aa group) and aspartate transaminase (ast) (196.2 ± 37.4 & 204 ± 30 vs 392.7 ± 35.6 in aa group). |
2021-09-08 |
2023-08-13 |
rat |
| Takahito Takase, Tsudoi Toyoda, Naoyuki Kobayashi, Takashi Inoue, Tomoko Ishijima, Keiko Abe, Hiroshi Kinoshita, Youichi Tsuchiya, Shinji Okad. Dietary iso-α-acids prevent acetaldehyde-induced liver injury through Nrf2-mediated gene expression. PloS one. vol 16. issue 2. 2021-09-07. PMID:33544749. |
the acetaldehyde-induced increases in serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels were suppressed by iso-α-acids intake. |
2021-09-07 |
2023-08-13 |
mouse |
| Meng Liu, Xuming Lin, Qiaoyin Tan, Xiaotong Ha. Evidence-Based Analysis of the Emergency Temporary Cardiac Pacing (Electrical Stimulation from Metal Wire Electrode). Bioinorganic chemistry and applications. vol 2021. 2021-09-07. PMID:34484317. |
(4) ast (aspartate transaminase) and alt (alanine aminotransferase) have a significant positive impact on ddi (d-dimer), while ctni has a significant negative impact on ddi. |
2021-09-07 |
2023-08-13 |
Not clear |
| Di Zeng, Yaping Wang, Yi Chen, Danyang Li, Guoli Li, Hanxianzhi Xiao, Jiyin Hou, Ziling Wang, Ling Hu, Lu Wang, Jing L. Angelica Polysaccharide Antagonizes 5-FU-Induced Oxidative Stress Injury to Reduce Apoptosis in the Liver Through Nrf2 Pathway. Frontiers in oncology. vol 11. 2021-09-07. PMID:34485154. |
asp alleviated 5-fu-induced the increase in alanine aminotransferase (alt), triglyceride (tg), and aspartate aminotransferase (ast) content; hepatic steatosis; and liver fibrosis. |
2021-09-07 |
2023-08-13 |
mouse |
| Chukwuemeka Ogbonna Okoro, Chinyere Aloke, Udu Ama Ibiam, Nwogo Ajuka Obasi, Obasi Uche Orji, Egwu Chinedu Ogbonnia, Patience Nkemjika Ogbu, Chinedum Uche Emelike, Godswill Odumero Ufebe, Nkiru Nwamaka Ezean. Studies on Ethanol Extracts of Pakistan journal of biological sciences : PJBS. vol 24. issue 6. 2021-09-07. PMID:34486349. |
<b>results:</b> obtained results showed a significant rise in the serum levels of aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), malondialdehyde (mda) and bilirubin as well as decreased albumin (alb), superoxide dismutase (sod), catalase (cat), reduced glutathione (gsh) in ccl<sub>4</sub>-challenged rats. |
2021-09-07 |
2023-08-13 |
rat |
| Ghadha Ibrahim Fouad, Mohamed R Mous. The protective potential of alpha lipoic acid on amiodarone-induced pulmonary fibrosis and hepatic injury in rats. Molecular and cellular biochemistry. vol 476. issue 9. 2021-09-06. PMID:33973131. |
amd administration resulted in elevated lung contents of hydroxyproline (hyp), malondialdehyde (mda), and increased serum levels of transforming growth factor beta-1 (tgf-β1), interferon-γ (ifn-γ), alanine amino transaminase (alt), aspartate amino transaminase (ast), total cholesterol (tc), and glucose. |
2021-09-06 |
2023-08-13 |
rat |
| Donghua Du, Wenting Lv, Rina Su, Chunwei Yu, Xiaoxia Jing, Nuwenqimuge Bai, Surong Has. Hydrolyzed camel whey protein alleviated heat stress-induced hepatocyte damage by activated Nrf2/HO-1 signaling pathway and inhibited NF-κB/NLRP3 axis. Cell stress & chaperones. vol 26. issue 2. 2021-09-03. PMID:33405053. |
s-cwp also alleviated hs-induced hepatocyte injury by reducing alanine aminotransferase (alt), aspartate aminotransferase (ast), and alkaline phosphatase (alp) levels and restoring heat shock protein 70 (hsp70) expression. |
2021-09-03 |
2023-08-13 |
cat |
| Omnia S Erfan, Hany M A Sonpol, Marwa Abd El-Kade. Protective effect of rapamycin against acrylamide-induced hepatotoxicity: The associations between autophagy, apoptosis, and necroptosis. Anatomical record (Hoboken, N.J. : 2007). vol 304. issue 9. 2021-09-03. PMID:33480149. |
blood samples were collected to assess alanine aminotransferase (alt) and aspartate aminotransferase (ast). |
2021-09-03 |
2023-08-13 |
rat |
| Arbinda Pokharel, Sudhamshu Kc, Pukar Thapa, Niyanta Karki, Rupesh Shrestha, Bikash Jaishi, Mukesh S Paude. The Effect of Empagliflozin on Liver Fat in Type 2 Diabetes Mellitus Patients With Non-Alcoholic Fatty Liver Disease. Cureus. vol 13. issue 7. 2021-09-03. PMID:34466320. |
results there was a significant decrease in mean cap value from 282.07 ± 47.29 db/m to 263.07 ± 49.93 db/m and ls from 5.89 ± 4.23 kpa to 5.04 ± 1.49 kpa along with a significant decrease in serum alanine aminotransferase (alt), aspartate aminotransferase (ast), and gamma-glutamyl transferase (ggt) among the patients. |
2021-09-03 |
2023-08-13 |
Not clear |
| B Ahmad, I Ilahi, A M Yousafzai, M Attaullah, A Rahim, D Naz, A Hazrat, G E-S Batiha, M A Nassan, A A K Khali. Protective effects of Zizyphus oxyphyla on liver and kidney related serum biomarkers in (CCl4) intoxicate rabbits. Brazilian journal of biology = Revista brasleira de biologia. vol 83. 2021-09-03. PMID:34468522. |
treatment with (zox-lme) significantly (p<0.05) reduced and normalized the levels of serum alanine transaminase (alt) aspartate transaminase (ast) and alkaline phosphatase (alp) and hematological indices. |
2021-09-03 |
2023-08-13 |
cat |
| Song Ye, Ling-Li Ren, Xi Chen, Bing Zhao, Yang Yang, Ling Weng, Peng Cao, Juan Y. [Protective effect and mechanism of Wangshi Baochi Pills against acute alcoholic liver/stomach injury in mice]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 15. 2021-09-03. PMID:34472266. |
the staining of liver pathological sections as well as the detection of serum aspartate aminotransferase(ast) and alanine aminotransferase(alt) and liver ros levels revealed that wsbc pills protected the liver by reducing serum ast and alt. |
2021-09-03 |
2023-08-13 |
mouse |
| Qian Zhang, Meng-Meng Shang, Qu-Fei Ling, Xiao-Ping Wu, Chun-Yu Li. Hepatoprotective effects of loach (Misgurnus anguillicaudatus) lyophilized powder on dimethylnitrosamine-induced liver fibrosis in rats. Archives of pharmacal research. vol 44. issue 8. 2021-09-02. PMID:25074038. |
after treatment with mlp (50, 100, 200 mg/kg), alanine aminotransferase (alt), aspartate aminotransferase (ast), albumin (alb), total protein (tp) and hydroxyproline (hyp) levels were detected, to assess the destruction of hepatocytes and the extent of liver fibrosis. |
2021-09-02 |
2023-08-13 |
rat |
| Marwan Almoiliqy, Jin Wen, Eskandar Qaed, Yuchao Sun, Mengqiao Lian, Haithm Mousa, Mahmoud Al-Azab, Mohamed Y Zaky, Dapeng Chen, Li Wang, Abdulkarem Al-Sharabi, Zhihao Liu, Pengyuan Sun, Yuan Li. Protective Effects of Cinnamaldehyde against Mesenteric Ischemia-Reperfusion-Induced Lung and Liver Injuries in Rats. Oxidative medicine and cellular longevity. vol 2020. 2021-09-02. PMID:33381264. |
ca pretreatment significantly restored the levels of aspartate transaminase (ast) and alanine transaminase (alt) in mesenteric i/r-injured liver tissues, indicating the improvement of hepatic function. |
2021-09-02 |
2023-08-13 |
rat |
| Ning Zhang, Yunfei Qu, Bo Qi. Sodium butyrate ameliorates non-alcoholic fatty liver disease by upregulating miR-150 to suppress CXCR4 expression. Clinical and experimental pharmacology & physiology. vol 48. issue 8. 2021-09-02. PMID:33721354. |
there were elevated contents of triacylglycerides (tg), total cholesterol (tc), high-density lipoprotein cholesterol (hdl-c), low-density lipoprotein cholesterol (ldl-c), fasting blood glucose, enhanced activities of alanine aminotransferase(alt) and aspartate aminotransferase(ast), increased homeostatic model assessment of insulin resistance scores and increased inflammatory responses in the serum of hfd-fed mice. |
2021-09-02 |
2023-08-13 |
mouse |
| Li Guo, Li Zhang, Haiman Xu, Pei Yu, Zhigang Wang, Danyi Lu, Min Chen, Baojian W. Diurnal hepatic CYP3A11 contributes to chronotoxicity of the pyrrolizidine alkaloid retrorsine in mice. Xenobiotica; the fate of foreign compounds in biological systems. vol 51. issue 9. 2021-09-02. PMID:34311664. |
hepatotoxicity was assessed by measuring plasma alt (alanine aminotransferase) and ast (aspartate aminotransferase) levels. |
2021-09-02 |
2023-08-13 |
mouse |
| Muhammad Atique, Atif Ghafoor, Rabia Javed, Noor Fatima, Anam Yousaf, Samana Zahr. Correlation of Viral Load With the Clinical and Biochemical Profiles of COVID-19 Patients. Cureus. vol 13. issue 7. 2021-09-01. PMID:34462686. |
all the biochemical parameters analyzed (alanine transaminase (alt), aspartate aminotransferase (ast), albumin, bilirubin, c-reactive protein (crp), lactate dehydrogenase (ldh), ferritin, d-dimer, and total leucocyte count (tlc)) showed a significant p-value (<0.05) in all the three groups studied. |
2021-09-01 |
2023-08-13 |
Not clear |
| Da Hu, Li Zhang, Rong Jiang, Cuiting Liao, Juanjuan Xu, Shifang Jiang, Yongqiang Yang, Ling Lin, Jiayi Huang, Yi Shen, Li Tang, Longjiang L. Nicotinic Acid against Acetaminophen-Induced Hepatotoxicity via Sirt1/Nrf2 Antioxidative Pathway in Mice. Journal of nutritional science and vitaminology. vol 67. issue 3. 2021-08-31. PMID:34193673. |
the results showed that pretreatment of na markedly improved the survival rate, alleviated serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels and mitigated the histopathological injuries compared to apap-exposed mice. |
2021-08-31 |
2023-08-13 |
mouse |
| Hamid Reza Behboodi, Asghar Sedaghat, Atefeh Baradaran, Hadi Haghbin Nazarpa. The effects of the mixture of betaine, vitamin C, St John's wort (Hypericum perforatum L.), lavender, and Melissa officinalis on performance and some physiological parameters in broiler chickens exposed to heat stress. Poultry science. vol 100. issue 9. 2021-08-31. PMID:34358952. |
the sbm in t2 and t3 resulted in the lowest levels of malondialdehyde (mda), aspartate transaminase (ast), alanine aminotransferase (alt), and alkaline phosphatase (alp). |
2021-08-31 |
2023-08-13 |
Not clear |
| Wangquan Ji, Peiyu Zhu, Ruonan Liang, Liang Zhang, Yu Zhang, Yuexia Wang, Weiguo Zhang, Ling Tao, Shuaiyin Chen, Haiyan Yang, Yuefei Jin, Guangcai Dua. Coxsackievirus A2 Leads to Heart Injury in a Neonatal Mouse Model. Viruses. vol 13. issue 8. 2021-08-31. PMID:34452454. |
the activity of total aspartate transaminase (ast) and lactate dehydrogenase (ldh) was notably increased in heart tissues from infected mice. |
2021-08-31 |
2023-08-13 |
mouse |
| Kazuyuki Tobe, Hiroshi Maegawa, Ichiro Nakamura, Satoshi Un. Effect of ipragliflozin on liver function in Japanese type 2 diabetes mellitus patients: subgroup analysis of a 3-year post-marketing surveillance study (STELLA-LONG TERM). Endocrine journal. vol 68. issue 8. 2021-08-30. PMID:33827996. |
data on patients, adverse drug reactions (adrs), and changes in glycemic parameters and liver enzymes (aspartate aminotransferase [ast], alanine aminotransferase [alt], gamma-glutamyl transpeptidase [γ-gtp] and alkaline phosphatase [alp]) were collected, and the fatty liver index (fli) was calculated. |
2021-08-30 |
2023-08-13 |
Not clear |