| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zuleyha Erisgin, Murat Ust. Does melamine exposure during infancy cause rhabdomyolysis? Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 96. issue 2. 2021-09-17. PMID:32527200. |
we found that the 75 mg/kg melamine group exhibited a significant increase in plasma aspartate aminotransferase (ast) activity compared to the other groups. |
2021-09-17 |
2023-08-13 |
rat |
| Taseen Syed, Nikita Chadha, Dhiren Kumar, Gaurav Gupta, Richard K Sterlin. Non-Invasive Assessment of Liver Fibrosis and Steatosis in End-Stage Renal Disease Patients Undergoing Renal Transplant Evaluation. Gastroenterology research. vol 14. issue 4. 2021-09-17. PMID:34527094. |
the aim of this study was to assess non-invasive testing including transient elastography (te) for liver stiffness (ls), controlled attenuated parameter (cap) for steatosis, fibrosis-4 (fib-4) score, aspartate aminotransferase (ast) to platelet ratio index (apri) and nafld fibrosis score (nfs), for evaluation of nafld along with advanced fibrosis (af) in patients with esrd undergoing renal transplant evaluation. |
2021-09-17 |
2023-08-13 |
Not clear |
| Xiao-Yu Song, Rong-Hua Li, Wei-Wei Liu, Toshihiko Hayashi, Kazunori Mizuno, Shunji Hattori, Hitomi Fujisaki, Takashi Ikejim. Effect of silibinin on ethanol- or acetaldehyde-induced damge of mouse primary hepatocytes in vitro. Toxicology in vitro : an international journal published in association with BIBRA. vol 70. 2021-09-16. PMID:33137447. |
surprisingly, silibinin significantly increased the cell viability and reduced the leakage of alanine amino transferase (alt) and aspartate amino transferase (ast) in acetaldehyde-treated hepatocytes, suggesting that silibinin protected cell injury caused by acetaldehyde treatment. |
2021-09-16 |
2023-08-13 |
mouse |
| Carmen Daniela Neagoe, Anca Smaranda Farmazon, Anca Maria Amzolini, Cristina Elena Singer, Simona Laura Ianoşi, Cristina Violeta Tutunaru, Amelia Valentina Genunche-Dumitrescu, Nicolae Gabriel Ianoşi, Ion Păun, Polliana Mihaela Leru, Oana Sorina Tica, Mihaela Popesc. The role of non-invasive scores in determining the liver fibrosis in NAFLD and psoriatic patients. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. vol 61. issue 2. 2021-09-16. PMID:33544802. |
based on the clinical and laboratory data, we calculated the following scores for fibrosis: body mass index (bmi), aspartate aminotransferase (ast)∕alanine aminotransferase (alt) ratio, diabetes (bard) score, fibrosis-4 (fib-4) score, and nafld fibrosis score (nfs). |
2021-09-16 |
2023-08-13 |
Not clear |
| Yifei Lu, James R Pike, Elizabeth Selvin, Thomas Mosley, Priya Palta, A Richey Sharrett, Alvin Thomas, Laura Loehr, A Sidney Barritt, Ron C Hoogeveen, Gerardo Heis. Low Liver Enzymes and Risk of Dementia: The Atherosclerosis Risk in Communities (ARIC) Study. Journal of Alzheimer's disease : JAD. vol 79. issue 4. 2021-09-15. PMID:33459646. |
low levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast) in the low physiologic range, surrogate markers for reduced liver metabolic function, are associated with cerebral hypometabolism, impairment in neurotransmitter production and synaptic maintenance, and a higher prevalence of dementia. |
2021-09-15 |
2023-08-13 |
Not clear |
| Aditi Ghosh, Claire Onsager, Andrew Mason, Leon Arriola, William Lee, Anuj Mubay. The role of oxygen intake and liver enzyme on the dynamics of damaged hepatocytes: Implications to ischaemic liver injury via a mathematical model. PloS one. vol 16. issue 4. 2021-09-15. PMID:33886563. |
we develop a mathematical model capturing dynamics of hepatocytes in the liver through the rise and fall of associated liver enzymes aspartate transaminase (ast), alanine transaminase (alt) and lactate dehydrogenase (ldh) related to the condition of ih. |
2021-09-15 |
2023-08-13 |
Not clear |
| Cuizhen Long, Na Xie, Yuanhui Shu, Yafeng Wu, Ping He, Yan Zhou, Yining Xiang, Junying Gu, Lei Yang, Yuping Wan. Knockout of the Cannabinoid Receptor 2 Gene Promotes Inflammation and Hepatic Stellate Cell Activation by Promoting A20/Nuclear Factor-κB (NF-κB) Expression in Mice with Carbon Tetrachloride-Induced Liver Fibrosis. Medical science monitor : international medical journal of experimental and clinical research. vol 27. 2021-09-15. PMID:34413280. |
hepatic damage and hepatic fibrosis were evaluated by detecting serum alanine aminotransferase (alt), aspartate aminotransferase (ast), and staining paraffin sections of liver tissue with hematoxylin-eosin (he). |
2021-09-15 |
2023-08-13 |
mouse |
| Mohammad Yahya Karimi, Iman Fatemi, Heibatullah Kalantari, Mohammad Amin Mombeini, Saeed Mehrzadi, Mehdi Goudarz. Ellagic Acid Prevents Oxidative Stress, Inflammation, and Histopathological Alterations in Acrylamide-Induced Hepatotoxicity in Wistar Rats. Journal of dietary supplements. vol 17. issue 6. 2021-09-14. PMID:31342809. |
aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), nitric oxide (no), protein carbonyl (pc), malondialdehyde (mda), tumor necrosis factor alpha (tnf-α), and interleukin 1 beta (il-1β) levels increased as a result of acr administration. |
2021-09-14 |
2023-08-13 |
rat |
| Yoshihisa Takahashi, Shiori Watabe, Arisa Togashi-Kumagai, Masato Watanabe, Erdenetsogt Dungubat, Hiroyuki Kusano, Yasuyuki Kobayashi, Naoki Harada, Ryoichi Yamaji, Keiichiro Sugimoto, Toshio Fukusat. Effects of low ethanol consumption on nonalcoholic steatohepatitis in mice. Alcohol (Fayetteville, N.Y.). vol 87. 2021-09-14. PMID:32553943. |
serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels were significantly lower in the low-ethanol group than in the high-fat group (p = 0.033 and 0.037, respectively). |
2021-09-14 |
2023-08-13 |
mouse |
| Leticia Díez-Quijada, Rosario Moyano, Verónica Molina-Hernández, Ana M Cameán, Ángeles Jo. Evaluation of toxic effects induced by repeated exposure to Cylindrospermopsin in rats using a 28-day feeding study. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 151. 2021-09-14. PMID:33741479. |
only in females some biochemical parameters (triglycerides (trig) levels and aspartate aminotransferase (ast) activity) as well as changes in the weight of organs (absolute liver weight values, relative kidney/body weight ratios or relative liver weight/brain weight ratios) were altered, but without toxicological relevance. |
2021-09-14 |
2023-08-13 |
rat |
| Leila Hashemi, Qi Zhang, Darios Getahun, Guneet K Jasuja, Courtney McCracken, Joseph Pisegna, Douglas Roblin, Michael J Silverberg, Vin Tangpricha, Suma Vupputuri, Michael Goodma. Longitudinal Changes in Liver Enzyme Levels Among Transgender People Receiving Gender Affirming Hormone Therapy. The journal of sexual medicine. vol 18. issue 9. 2021-09-13. PMID:34366264. |
the effect of gender affirming hormone therapy (gaht) on clinical laboratory parameters, including levels of liver enzymes alanine aminotransferase (alt) and aspartate transaminase (ast), is an area of uncertainty in transgender health. |
2021-09-13 |
2023-08-13 |
Not clear |
| Fengling Zhou, Wei She, Lin He, Jiuqun Zhu, Lu G. The effect of anthocyanins supplementation on liver enzymes among patients with metabolic disorders: A systematic review and meta-analysis of randomized clinical trials. Phytotherapy research : PTR. 2021-09-12. PMID:34510592. |
online databases including pubmed/medline, scopus, isi web of science, and cochrane library were searched up to june 2020 for randomized controlled trials (rcts) that examined the effect of anthocyanin supplementation on serum levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast) among patients with metabolic disorders. |
2021-09-12 |
2023-08-13 |
Not clear |
| Ping Chen, Yusheng Li, Li Xia. Berberine ameliorates nonalcoholic fatty liver disease by decreasing the liver lipid content via reversing the abnormal expression of MTTP and LDLR. Experimental and therapeutic medicine. vol 22. issue 4. 2021-09-11. PMID:34504563. |
the liver wet weight of rats in each group was measured, the liver tissue structure was observed by microscopy, and alanine aminotransferase (alt), aspartate aminotransferase (ast), total cholesterol (tc), triglyceride (tg), fasting blood glucose (fbg), low-density lipoprotein (ldl) and high-density lipoprotein (hdl) levels were detected using a semi-automatic biochemical detector. |
2021-09-11 |
2023-08-13 |
rat |
| Jung-Yun Lee, Tae Yang Kim, Hanna Kang, Jungbae Oh, Joo Woong Park, Se-Chan Kim, Minjoo Kim, Emmanouil Apostolidis, Young-Cheul Kim, Young-In Kwo. Anti-Obesity and Anti-Adipogenic Effects of Chitosan Oligosaccharide (GO2KA1) in SD Rats and in 3T3-L1 Preadipocytes Models. Molecules (Basel, Switzerland). vol 26. issue 2. 2021-09-10. PMID:33440605. |
we assessed body weight, food intake, plasma lipids, levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast) for liver function, and serum level of adiponectin, a marker for obesity-mediated metabolic syndrome. |
2021-09-10 |
2023-08-13 |
rat |
| Defeng Xu, Jiaxin Wu, Lijun Sun, Xiaoming Qin, Xiuping Fan, Xiaoxian Zhen. Combined stress of acute cold exposure and waterless duration at low temperature induces mortality of shrimp Litopenaeus vannamei through injuring antioxidative and immunological response in hepatopancreas tissue. Journal of thermal biology. vol 100. 2021-09-10. PMID:34503768. |
for immunity response, the total hemocyte counts (thc) decreased with the prolongation of duration time and the activities of non-specific immunity enzymes such as phenol oxidase (po), acid phosphatase (acp), alkaline phosphatase (akp), aspartate aminotransferase (ast) and alanine transaminase (alt) were significantly elevated in ac + wd9h groups (p < 0.05). |
2021-09-10 |
2023-08-13 |
cat |
| Bijing Yang, Yingwei Liu, Yangwei Li, Shanshan Zhu, Yuanliang Li, Jiangnan Yi, Zhuanxu Ouyang, Bingxian Liu, Khalid Mehmood, Riaz Hussain, Jiaqiang Pan, Lianmei Hu, Zhaoxin Tang, Guanhua Wang, Ying Li, Hui Zhan. Exposure to the herbicide butachlor activates hepatic stress signals and disturbs lipid metabolism in mice. Chemosphere. vol 283. 2021-09-09. PMID:34146870. |
results indicated that exposure to butachlor induced hepatotoxicity in terms of swelling of hepatocyte, disorders in the arrangement of hepatic cells, increased concentrations of different serum enzymes such as alkaline phosphate (alp) and aspartate aminotransferase (ast). |
2021-09-09 |
2023-08-13 |
mouse |
| Grace E Obiyo, Opeoluwa M Ogunsuyi, Adeyi Akindele . Evaluation of long-term dermal exposure to soil contaminated with spent engine oil in male Wistar rats: An experimental approach. Toxicology and industrial health. vol 36. issue 12. 2021-09-08. PMID:33108250. |
heavy metal (lead (pb), nickel (ni), zinc, and cadmium (cd)) accumulations, hematology, biochemical (aspartate aminotransferase (ast), alanine aminotransferase, alkaline phosphatase (alp), urea, and creatinine) parameters, sperm morphology, and histopathology (liver, kidney, lungs, brain, skin, and testis) were evaluated as end points. |
2021-09-08 |
2023-08-13 |
rat |
| Baran Akagunduz, Muhammet Ozer, Fatih Ozcıcek, Ali Veysel Kara, Sahin Lacın, Mustafa Özkaraca, Abdulkadir Çoban, Bahadır Suleyman, Renad Mammadov, Halis Suleyma. Protective effects of taxifolin on pazopanib-induced liver toxicity: an experimental rat model. Experimental animals. vol 70. issue 2. 2021-09-08. PMID:33239495. |
tgsh and tas levels were lower in the pp group than in the tpp and c groups (p<0.001), and the aspartate aminotransferase (ast), alanine aminotransferase (alt), and lactate dehydrogenase (ldh) levels were higher. |
2021-09-08 |
2023-08-13 |
rat |
| Nada H Eisa, Mohamed El-Sherbiny, Nada F Abo El-Mag. Betulin alleviates cisplatin-induced hepatic injury in rats: Targeting apoptosis and Nek7-independent NLRP3 inflammasome pathways. International immunopharmacology. vol 99. 2021-09-08. PMID:34217992. |
betulin significantly improved serum aspartate transaminase (ast), alanine transaminase (alt), albumin and total bilirubin levels in comparison with cisplatin group. |
2021-09-08 |
2023-08-13 |
rat |
| Amir Mohamed Abdelhamid, Ahmed Ramadan Elsheakh, Ghada Mohamed Suddek, Rania Ramadan Abdelazi. Telmisartan alleviates alcohol-induced liver injury by activation of PPAR-γ/ Nrf-2 crosstalk in mice. International immunopharmacology. vol 99. 2021-09-08. PMID:34273638. |
our results showed that tel (10 mg/kg/day) has the ability to reduce serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), and alkaline phosphatase (alp). |
2021-09-08 |
2023-08-13 |
mouse |