| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S M M Vasconcelos, R F Pereira, R S Alves, A C V Arruda Filho, L M V Aguiar, D S Macedo, R M Freitas, M G R Queiroz, F C F Sousa, G S B Vian. Effects of ethanol and haloperidol on plasma levels of hepatic enzymes, lipid profile, and apolipoprotein in rats. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 82. issue 2. 2004-11-24. PMID:15060626. |
results show increases in alanine transaminase (alt; 48% and 55%) and aspartate transaminase (ast; 32% and 22%) levels after ethanol or haloperidol (14 days) treatments, as compared with controls. |
2004-11-24 |
2023-08-12 |
rat |
| Sherif Y Saad, Tawfeeg A O Najjar, Mouied Alashar. Cardiotoxicity of doxorubicin/paclitaxel combination in rats: effect of sequence and timing of administration. Journal of biochemical and molecular toxicology. vol 18. issue 2. 2004-11-19. PMID:15122649. |
dox-induced cardiotoxicity was manifested by abnormal biochemical changes including marked increases in serum creatine phosphokinase isoenzyme (ck-mb), lactate dehydrogenase (ldh), glutathione peroxidase (gsh-px), and aspartate aminotransferase (ast) activity levels. |
2004-11-19 |
2023-08-12 |
rat |
| Anthony J G Hanley, Ken Williams, Andreas Festa, Lynne E Wagenknecht, Ralph B D'Agostino, Judy Kempf, Bernard Zinman, Steven M Haffne. Elevations in markers of liver injury and risk of type 2 diabetes: the insulin resistance atherosclerosis study. Diabetes. vol 53. issue 10. 2004-11-16. PMID:15448093. |
a limited number of studies have reported associations of markers of liver injury, including elevated concentrations of aspartate aminotransferase (ast) and alanine aminotransferase (alt), with prospective risk of type 2 diabetes. |
2004-11-16 |
2023-08-12 |
human |
| Aloísio Luiz Benedetti, Cidônia de Lourdes Vituri, Andréa Gonçalves Trentin, Maria Aparecida Custódio Domingues, Marcio Alvarez-Silv. The effects of sub-chronic exposure of Wistar rats to the herbicide Glyphosate-Biocarb. Toxicology letters. vol 153. issue 2. 2004-11-16. PMID:15451553. |
sub-chronic treatment of animals starting from the lowest dose of glyphosate induced the leakage of hepatic intracellular enzymes, alanine aminotransferase (alt) and aspartate aminotransferase (ast), suggesting irreversible damage in hepatocytes. |
2004-11-16 |
2023-08-12 |
rat |
| Viroj Wiwanitki. Activated partial thromboplastin time abnormality in patients with cholangiocarcinoma. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. vol 10. issue 1. 2004-11-09. PMID:14979409. |
the only two parameters that showed significant correlation are alanine aminotransferase (alt) and aspartate aminotransferase (ast) (p < 0.05). |
2004-11-09 |
2023-08-12 |
Not clear |
| K Kamashi, A Gopala Reddy, K S Reddy, V R Redd. Evaluation of zinc against salinomycin toxicity in broilers. Indian journal of physiology and pharmacology. vol 48. issue 1. 2004-10-18. PMID:15270374. |
the activity of glutathione peroxidase, glutathione reductase and catalase, and the values of aspartate aminotransferase (ast), alanine aminotransferase (alt), total proteins, total cholesterol, triglycerides, low density lipoproteins (ldl), urea, creatinine and blood urea nitrogen (bun) were significantly (p<0.01) elevated in toxic controls, whereas glutathione (gsh) and high density lipoproteins (hdl) were significantly (p<0.01) lowered as compared to group 1, 2, 4 and 5. |
2004-10-18 |
2023-08-12 |
Not clear |
| Hany Z Rofae. Effect of ketamine pretreatment on cocaine-mediated hepatotoxicity in rats. Toxicology letters. vol 152. issue 3. 2004-10-18. PMID:15331130. |
serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) were measured as markers of liver injury. |
2004-10-18 |
2023-08-12 |
rat |
| Saburo Murakami, Katsuhiko Okubo, Yoshitaka Tsuji, Hideto Sakata, Takehiro Takahashi, Masataka Kikuchi, Renzo Hirayam. Changes in liver enzymes after surgery in anti-hepatitis C virus-positive patients. World journal of surgery. vol 28. issue 7. 2004-10-14. PMID:15175902. |
serum levels of aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), lactate dehydrogenase (ldh), and cholinesterase (che) were the standard liver tests performed. |
2004-10-14 |
2023-08-12 |
Not clear |
| Victor de Lédinghen, Michel Combes, Hélène Trouette, Maria Winnock, Michel Amouretti, Antoine de Mascarel, Patrice Couzigo. Should a liver biopsy be done in patients with subclinical chronically elevated transaminases? European journal of gastroenterology & hepatology. vol 16. issue 9. 2004-10-12. PMID:15316412. |
significant differences were observed between f < 2 and f > or = 2 fibrosis patients for aspartate aminotransferase (ast) and alt and between patients with nash or without for body mass index. |
2004-10-12 |
2023-08-12 |
human |
| Sadakat Ozdil, Sehnaz Bolkent, Refiye Yanardag, Pelin Arda-Pirincc. Protective effects of ascorbic acid, dl-alpha-tocopherol acetate, and sodium selenate on ethanol-induced liver damage of rats. Biological trace element research. vol 97. issue 2. 2004-10-08. PMID:14985625. |
in the group administered ethanol, a reduction of the blood glutathione (gsh) level and increases in serum values of alanine aminotranserase (alt), aspartate aminotransferase (ast), lactate dehydrogenase (ldh), alkaline phosphatase (alp), and gamma-glutamyl transferase (ggt) activities were observed, whereas in the control group, the reverse was found to occur. |
2004-10-08 |
2023-08-12 |
rat |
| Kyoichiro Maeshima, Toru Takahashi, Kiichi Nakahira, Hiroko Shimizu, Hiromi Fujii, Hiroshi Katayama, Masataka Yokoyama, Kiyoshi Morita, Reiko Akagi, Shigeru Sass. A protective role of interleukin 11 on hepatic injury in acute endotoxemia. Shock (Augusta, Ga.). vol 21. issue 2. 2004-10-07. PMID:14752286. |
lps treatment induced severe hepatic injury as revealed by marked increases in serum alanine transaminase (alt) and aspartate transaminase (ast) activities, extensive hepatocyte necrosis, tumor necrosis factor-alpha (tnf-alpha) mrna, inducible nitric oxide synthase (inos) mrna, and dna-binding activity of nuclear factor-kappab (nf-kappab). |
2004-10-07 |
2023-08-12 |
human |
| Takashi Hanioka, Yukiko Shigemoto, Ryoichi Matsuse, Miki Ojima, Satoshi Shizukuish. Effect of follow-up intervention of toothbrushing on periodontal health in workplace dental examination. Journal of occupational health. vol 46. issue 3. 2004-10-07. PMID:15215661. |
aspartate aminotransferase (ast) in gcf was determined. |
2004-10-07 |
2023-08-12 |
Not clear |
| Takashi Shimizu, Itsuko Horiguchi, Tokiko Kato, Shoji Nagat. Relationship between an interview-based health promotion program and cardiovascular risk factors at Japanese companies. Journal of occupational health. vol 46. issue 3. 2004-10-07. PMID:15215662. |
with agreement of the subject companies, we compared the delta of each item, including body mass index (bmi), systolic blood pressure (sbp), diastolic blood pressure (dbp), serum total cholesterol (t-cho), serum aspartate aminotransaminase (ast), serum alanine aminotransferase (alt), and serum gammaglutamyl transpeptidase (ggtp), in the intervention with that in the reference. |
2004-10-07 |
2023-08-12 |
human |
| M Diez, C Michaux, I Jeusette, P Baldwin, L Istasse, V Biourg. Evolution of blood parameters during weight loss in experimental obese Beagle dogs. Journal of animal physiology and animal nutrition. vol 88. issue 3-4. 2004-10-06. PMID:15059242. |
the effects of weight loss on hormonal and biochemical blood parameters were measured monthly [carnitine, creatinine, urea, free t4 (ft4), total t4 (tt4), plasma alkaline phosphatases (alp), aspartate aminotransferase (ast), alanine aminotransferase (alt), potassium and total proteins] or bimonthly [cholesterol, triglycerides, non-esterified fatty acids (nefa), insulin-like growth factor i (igf-i), glucose, insulin] in eight obese beagles dogs fed either a high protein dry diet, dp (crude protein 47.5%, on dry matter basis) or a commercial high fibre diet, hf (crude protein 23.8%, crude fibre 23.3%). |
2004-10-06 |
2023-08-12 |
Not clear |
| Sung Ho Hyon, María Candela Ceballos, Mariana Barbich, Rosana Groppa, Luis Grosembacher, María Mercedes Vieiro, Laura Barcan, Salomon Algranati, Leon Litwak, Pablo F Argiba. Effect of the embolization of completely unpurified islets on portal vein pressure and hepatic biochemistry in clinical practice. Cell transplantation. vol 13. issue 1. 2004-10-05. PMID:15040606. |
peak aspartate aminotransferase (ast), alanine aminotransferase (alt), and serum amylase were 109.4 +/- 61.2 iu/l (basal vs. peak, not significant), 79.5 +/- 56.9 iu/l (basal vs. peak, not significant), and 887.5 +/- 153.6 iu/l (basal vs. peak, p = 0.02), respectively. |
2004-10-05 |
2023-08-12 |
Not clear |
| Lorenza Di Pascoli, Alessia Lion, Daniela Milazzo, Lorenza Caregar. Acute liver damage in anorexia nervosa. The International journal of eating disorders. vol 36. issue 1. 2004-10-05. PMID:15185281. |
biochemical evaluation showed a marked increase in serum levels of aspartate aminotransferases (ast = 9,980 iu/l), alanine aminotransferase (alt = 3,930 iu/l), amylase (1,002 iu/l), lipase (1,437 iu/l), creatine phosphokinase (cpk; 783 iu/l), and lactate dehydrogenase (ldh = 6,830 iu/l). |
2004-10-05 |
2023-08-12 |
Not clear |
| Zhongmin Liu, Zhenping Xu, Wenlu Shen, Yi Li, Jun Zhang, Xin Y. Effect of pharmacologic preconditioning with tetrandrine on subsequent ischemia/reperfusion injury in rat liver. World journal of surgery. vol 28. issue 6. 2004-09-30. PMID:15366756. |
blood samples were taken for measurement of alanine aminotransferase (alt), aspartate aminotransferase (ast), and lactate dehydrogenase (ldh). |
2004-09-30 |
2023-08-12 |
rat |
| T Andrew Clayton, John C Lindon, Jeremy R Everett, Claude Charuel, Gilles Hanton, Jean-Loic Le Net, Jean-Pierre Provost, Jeremy K Nicholso. Hepatotoxin-induced hypercreatinaemia and hypercreatinuria: their relationship to one another, to liver damage and to weakened nutritional status. Archives of toxicology. vol 78. issue 2. 2004-09-28. PMID:14520508. |
at the same time there were nine out of ten points of correspondence between the incidence of hypercreatinaemia and/or hypercreatinuria and the incidence of increases in plasma aspartate aminotransferase (ast) activity. |
2004-09-28 |
2023-08-12 |
rat |
| Mona M Mantawy, Manal A Hamed, Elham M Sammour, Mahmoud Sana. Influence of Capparis spinosa and Acacia arabica on certain biochemical haemolymph parameters of Biomphalaria alexandrina. Journal of the Egyptian Society of Parasitology. vol 34. issue 2. 2004-09-28. PMID:15287187. |
the effect of the two plants on lactate dehydrogenase (ldh), 5'-nucleotidase, acid phosphatase (ap), aspartate and alanine aminotransferases (ast & alt), alkaline phosphatase (alp) and glucose content were studied. |
2004-09-28 |
2023-08-12 |
Not clear |
| Olubunmi Bolanle Ajayi, Adewale Odutug. Effect of low-zinc status and essential fatty acids deficiency on the activities of aspartate aminotransferase and alanine aminotransferase in liver and serum of albino rats. Die Nahrung. vol 48. issue 2. 2004-09-24. PMID:15146962. |
the effects of dietary deficiencies of zinc and essential fatty acids (efas) or both on aspartate aminotransferase (ast) and alanine aminotransferase (alt) were investigated in young growing rats. |
2004-09-24 |
2023-08-12 |
rat |