| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kyoichiro Maeshima, Toru Takahashi, Kiichi Nakahira, Hiroko Shimizu, Hiromi Fujii, Hiroshi Katayama, Masataka Yokoyama, Kiyoshi Morita, Reiko Akagi, Shigeru Sass. A protective role of interleukin 11 on hepatic injury in acute endotoxemia. Shock (Augusta, Ga.). vol 21. issue 2. 2004-10-07. PMID:14752286. |
lps treatment induced severe hepatic injury as revealed by marked increases in serum alanine transaminase (alt) and aspartate transaminase (ast) activities, extensive hepatocyte necrosis, tumor necrosis factor-alpha (tnf-alpha) mrna, inducible nitric oxide synthase (inos) mrna, and dna-binding activity of nuclear factor-kappab (nf-kappab). |
2004-10-07 |
2023-08-12 |
human |
| Takashi Hanioka, Yukiko Shigemoto, Ryoichi Matsuse, Miki Ojima, Satoshi Shizukuish. Effect of follow-up intervention of toothbrushing on periodontal health in workplace dental examination. Journal of occupational health. vol 46. issue 3. 2004-10-07. PMID:15215661. |
aspartate aminotransferase (ast) in gcf was determined. |
2004-10-07 |
2023-08-12 |
Not clear |
| Takashi Shimizu, Itsuko Horiguchi, Tokiko Kato, Shoji Nagat. Relationship between an interview-based health promotion program and cardiovascular risk factors at Japanese companies. Journal of occupational health. vol 46. issue 3. 2004-10-07. PMID:15215662. |
with agreement of the subject companies, we compared the delta of each item, including body mass index (bmi), systolic blood pressure (sbp), diastolic blood pressure (dbp), serum total cholesterol (t-cho), serum aspartate aminotransaminase (ast), serum alanine aminotransferase (alt), and serum gammaglutamyl transpeptidase (ggtp), in the intervention with that in the reference. |
2004-10-07 |
2023-08-12 |
human |
| M Diez, C Michaux, I Jeusette, P Baldwin, L Istasse, V Biourg. Evolution of blood parameters during weight loss in experimental obese Beagle dogs. Journal of animal physiology and animal nutrition. vol 88. issue 3-4. 2004-10-06. PMID:15059242. |
the effects of weight loss on hormonal and biochemical blood parameters were measured monthly [carnitine, creatinine, urea, free t4 (ft4), total t4 (tt4), plasma alkaline phosphatases (alp), aspartate aminotransferase (ast), alanine aminotransferase (alt), potassium and total proteins] or bimonthly [cholesterol, triglycerides, non-esterified fatty acids (nefa), insulin-like growth factor i (igf-i), glucose, insulin] in eight obese beagles dogs fed either a high protein dry diet, dp (crude protein 47.5%, on dry matter basis) or a commercial high fibre diet, hf (crude protein 23.8%, crude fibre 23.3%). |
2004-10-06 |
2023-08-12 |
Not clear |
| Sung Ho Hyon, María Candela Ceballos, Mariana Barbich, Rosana Groppa, Luis Grosembacher, María Mercedes Vieiro, Laura Barcan, Salomon Algranati, Leon Litwak, Pablo F Argiba. Effect of the embolization of completely unpurified islets on portal vein pressure and hepatic biochemistry in clinical practice. Cell transplantation. vol 13. issue 1. 2004-10-05. PMID:15040606. |
peak aspartate aminotransferase (ast), alanine aminotransferase (alt), and serum amylase were 109.4 +/- 61.2 iu/l (basal vs. peak, not significant), 79.5 +/- 56.9 iu/l (basal vs. peak, not significant), and 887.5 +/- 153.6 iu/l (basal vs. peak, p = 0.02), respectively. |
2004-10-05 |
2023-08-12 |
Not clear |
| Lorenza Di Pascoli, Alessia Lion, Daniela Milazzo, Lorenza Caregar. Acute liver damage in anorexia nervosa. The International journal of eating disorders. vol 36. issue 1. 2004-10-05. PMID:15185281. |
biochemical evaluation showed a marked increase in serum levels of aspartate aminotransferases (ast = 9,980 iu/l), alanine aminotransferase (alt = 3,930 iu/l), amylase (1,002 iu/l), lipase (1,437 iu/l), creatine phosphokinase (cpk; 783 iu/l), and lactate dehydrogenase (ldh = 6,830 iu/l). |
2004-10-05 |
2023-08-12 |
Not clear |
| Zhongmin Liu, Zhenping Xu, Wenlu Shen, Yi Li, Jun Zhang, Xin Y. Effect of pharmacologic preconditioning with tetrandrine on subsequent ischemia/reperfusion injury in rat liver. World journal of surgery. vol 28. issue 6. 2004-09-30. PMID:15366756. |
blood samples were taken for measurement of alanine aminotransferase (alt), aspartate aminotransferase (ast), and lactate dehydrogenase (ldh). |
2004-09-30 |
2023-08-12 |
rat |
| T Andrew Clayton, John C Lindon, Jeremy R Everett, Claude Charuel, Gilles Hanton, Jean-Loic Le Net, Jean-Pierre Provost, Jeremy K Nicholso. Hepatotoxin-induced hypercreatinaemia and hypercreatinuria: their relationship to one another, to liver damage and to weakened nutritional status. Archives of toxicology. vol 78. issue 2. 2004-09-28. PMID:14520508. |
at the same time there were nine out of ten points of correspondence between the incidence of hypercreatinaemia and/or hypercreatinuria and the incidence of increases in plasma aspartate aminotransferase (ast) activity. |
2004-09-28 |
2023-08-12 |
rat |
| Mona M Mantawy, Manal A Hamed, Elham M Sammour, Mahmoud Sana. Influence of Capparis spinosa and Acacia arabica on certain biochemical haemolymph parameters of Biomphalaria alexandrina. Journal of the Egyptian Society of Parasitology. vol 34. issue 2. 2004-09-28. PMID:15287187. |
the effect of the two plants on lactate dehydrogenase (ldh), 5'-nucleotidase, acid phosphatase (ap), aspartate and alanine aminotransferases (ast & alt), alkaline phosphatase (alp) and glucose content were studied. |
2004-09-28 |
2023-08-12 |
Not clear |
| Olubunmi Bolanle Ajayi, Adewale Odutug. Effect of low-zinc status and essential fatty acids deficiency on the activities of aspartate aminotransferase and alanine aminotransferase in liver and serum of albino rats. Die Nahrung. vol 48. issue 2. 2004-09-24. PMID:15146962. |
the effects of dietary deficiencies of zinc and essential fatty acids (efas) or both on aspartate aminotransferase (ast) and alanine aminotransferase (alt) were investigated in young growing rats. |
2004-09-24 |
2023-08-12 |
rat |
| Giuseppe M Campo, Angela Avenoso, Salvatore Campo, Angela D'Ascola, Alida M Ferlazzo, Alberto Calatron. The antioxidant and antifibrogenic effects of the glycosaminoglycans hyaluronic acid and chondroitin-4-sulphate in a subchronic rat model of carbon tetrachloride-induced liver fibrogenesis. Chemico-biological interactions. vol 148. issue 3. 2004-09-24. PMID:15276869. |
at the end of the 6-week treatment period (24 h after the last dose of gags), the following parameters were evaluated: (1) serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities, as index of hepatic cell disruption; (2) hepatic conjugated dienes (cd), as index of lipid peroxidation; (3) hepatic timps activity and expression; (4) hepatic superoxide dismutase (sod) and glutathione peroxidase (gpx) activity, as index of endogenous defences; (5) hepatic hydroxyproline, as index of collagen deposition. |
2004-09-24 |
2023-08-12 |
rat |
| Hiroshi Imamura, Norihiko Kokudo, Yasuhiko Sugawara, Keiji Sano, Jun-ichi Kaneko, Tadatoshi Takayama, Masatoshi Makuuch. Pringle's maneuver and selective inflow occlusion in living donor liver hepatectomy. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. vol 10. issue 6. 2004-09-23. PMID:15162472. |
the quality of the grafts was assessed and compared by determining maximum postoperative aspartate aminotransferase (ast) and alanine aminotransferase (alt) values. |
2004-09-23 |
2023-08-12 |
Not clear |
| Akira Hirao, Masao Yamasaki, Hitomi Chujo, Nami Koyanagi, Hiroaki Kanouchi, Shin Yasuda, Aya Matsuo, Eri Nishida, Tatsuya Rikimaru, Eiji Tsujita, Mitsuo Shimada, Yoshihiko Maehara, Hirofumi Tachibana, Koji Yamad. Effect of dietary conjugated linoleic acid on liver regeneration after a partial hepatectomy in rats. Journal of nutritional science and vitaminology. vol 50. issue 1. 2004-09-23. PMID:15228211. |
dietary cla did not affect serum aspartate aminotransferase (ast) or alanine aminotransferase (alt) activities. |
2004-09-23 |
2023-08-12 |
rat |
| Jennifer M Keller, John R Kucklick, M Andrew Stamper, Craig A Harms, Patricia D McClellan-Gree. Associations between organochlorine contaminant concentrations and clinical health parameters in loggerhead sea turtles from North Carolina, USA. Environmental health perspectives. vol 112. issue 10. 2004-09-21. PMID:15238280. |
all classes of ocs in the blood except dieldrin were correlated positively with aspartate aminotransferase (ast) activity, indicating possible hepatocellular damage. |
2004-09-21 |
2023-08-12 |
Not clear |
| Fatma M El-Demerdash, Mokhtar I Yousef, Fatma S Kedwany, Hoda H Baghdad. Cadmium-induced changes in lipid peroxidation, blood hematology, biochemical parameters and semen quality of male rats: protective role of vitamin E and beta-carotene. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 42. issue 10. 2004-09-20. PMID:15304303. |
the activities of glutathione s-transferase (gst) (plasma and liver), alkaline phosphatase (alp) (plasma and liver), aspartate aminotransferase (ast), alanine aminotransferase (alt) (liver) and acetylcholinesterase (ache) (plasma and brain) were significantly (p < 0.05) decreased due to cdcl2 administration, whereas, the activities of ast and alt were increased in plasma. |
2004-09-20 |
2023-08-12 |
human |
| A G Wang, T Xia, J Yuan, R A Yu, K D Yang, X M Chen, W Qu, M P Waalke. Effects of phenobarbital on metabolism and toxicity of diclofenac sodium in rat hepatocytes in vitro. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 42. issue 10. 2004-09-20. PMID:15304311. |
the decline of cyp 3a was partially reversed by cyp inducer pb, and the maximum induction of cyp 3a was 2.2-fold over control after continuous exposure of hepatocytes to 2 mm pb for 48 h. lactic dehydrogenase (ldh), aspartate transaminase (ast), and alanine transamine (alt) activity and the contents of the df-na metabolites 4'-hydroxydiclofenac (4'-oh-df) and 5-hydroxydiclofenac (5-oh-df) in media appeared to increase with increasing df-na concentrations, though there were no significant differences between df-na exposed and control hepatocytes. |
2004-09-20 |
2023-08-12 |
rat |
| Keng-Liang Wu, Sheng-Nan Lu, Chi-Sin Changchien, King-Wah Chiu, Chung-Huang Kuo, Seng-Kee Chuah, Jien-Wei Liu, Meng-Chih Lin, Hock-Liew Eng, Shun-Sheng Chen, Chuan-Mo Lee, Chao-Long Che. Sequential changes of serum aminotransferase levels in patients with severe acute respiratory syndrome. The American journal of tropical medicine and hygiene. vol 71. issue 2. 2004-09-17. PMID:15306699. |
serial serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels were retrospectively analyzed and hepatitis b surface antigen (hbsag) was also evaluated to correlate with the progression of this disease. |
2004-09-17 |
2023-08-12 |
Not clear |
| K H Janbaz, S A Saeed, A H Gilan. Studies on the protective effects of caffeic acid and quercetin on chemical-induced hepatotoxicity in rodents. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 11. issue 5. 2004-09-16. PMID:15330498. |
oral administration of sub-lethal dose of paracetamol (640 mg/kg) produced liver damage in rats as manifested by the significant (p<0.01) rise in serum levels of aminotransferases (aspartate transaminase (ast) and alanine transaminase (alt)) compared to respective control values. |
2004-09-16 |
2023-08-12 |
mouse |
| R S Devi, Shoba Narayan, K Vijai Mohan, K E Sabitha, C S Shyamala Dev. Effect of a polyherbal formulation, Ambrex, on butylated hydroxy toluene (BHT) induced toxicity in rats. Indian journal of experimental biology. vol 41. issue 11. 2004-09-16. PMID:15332500. |
liver damage was proved by elevated levels of serum protein and markers such as ldh, alp, aspartate amino transferase (ast), alanine amino transferase (alt), decreased level of lipid peroxides (lpo) in serum and glutathione (gsh) in liver. |
2004-09-16 |
2023-08-12 |
rat |
| Sarah Donald, Richard D Verschoyle, Peter Greaves, Tina Colombo, Massimo Zucchetti, Cristiano Falcioni, Marco Zaffaroni, Maurizio D'Incalci, Margaret M Manson, Jose Jimeno, William P Steward, Andreas J Gesche. Dietary agent indole-3-carbinol protects female rats against the hepatotoxicity of the antitumor drug ET-743 (trabectidin) without compromising efficacy in a rat mammary carcinoma. International journal of cancer. vol 111. issue 6. 2004-09-14. PMID:15300810. |
hepatotoxicity was adjudged by measurement of plasma levels of bilirubin, alkaline phosphatase (alp) and aspartate aminotransferase (ast) and by liver histopathology. |
2004-09-14 |
2023-08-12 |
rat |