| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J H Strømme, P Rustad, H Steensland, L Theodorsen, P Urda. Reference intervals for eight enzymes in blood of adult females and males measured in accordance with the International Federation of Clinical Chemistry reference system at 37 degrees C: part of the Nordic Reference Interval Project. Scandinavian journal of clinical and laboratory investigation. vol 64. issue 4. 2005-01-04. PMID:15223701. |
as part of the nordic reference interval project we present reference intervals for alanine transaminase (alt), aspartate transaminase (ast), creatine kinase (ck), lactate dehydrogenase (ld), alkaline phosphatase (alp), gamma-glutamyltransferase (gt), amylase (amy) and pancreatic type of amy in blood of adult males and females. |
2005-01-04 |
2023-08-12 |
Not clear |
| Thomas Visalli, Rita Turkall, Mohamed S Abdel-Rahma. Cocaine hepatotoxicity and its potentiation by lipopolysaccharide: treatment and gender effects. International journal of toxicology. vol 23. issue 3. 2004-12-22. PMID:15204719. |
plasma alanine aminotransferase (alt) and aspartate aminotransferase (ast) were evaluated as indices of liver injury. |
2004-12-22 |
2023-08-12 |
mouse |
| Yao Hong Wei, Li Jun, Chen Ji Qian. Effect of losartan, an angiotensin II antagonist, on hepatic fibrosis induced by CCl4 in rats. Digestive diseases and sciences. vol 49. issue 10. 2004-12-21. PMID:15573910. |
alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels in plasma and hydroxyproline (hyp) contents in liver tissue were assayed by spectrophotometry. |
2004-12-21 |
2023-08-12 |
rat |
| Saverio Stranges, Jo L Freudenheim, Paola Muti, Eduardo Farinaro, Marcia Russell, Thomas H Nochajski, Maurizio Trevisa. Greater hepatic vulnerability after alcohol intake in African Americans compared with Caucasians: a population-based study. Journal of the National Medical Association. vol 96. issue 9. 2004-12-14. PMID:15481746. |
this study was aimed at evaluating racial variations in common biomarkers of liver injury, such as gamma-glutamyltransferase (ggt), aspartate amino transferase (ast) and alanine amino transferase (alt), by categories of drinking status and levels of current alcohol use. |
2004-12-14 |
2023-08-12 |
Not clear |
| Patricia Grajeda-Cota, Marco Vinicio Ramírez-Mares, Elvira González de Mejí. Vitamin C protects against in vitro cytotoxicity of cypermethrin in rat hepatocytes. Toxicology in vitro : an international journal published in association with BIBRA. vol 18. issue 1. 2004-12-10. PMID:14630057. |
in vitro cell viability, lactate dehydrogenase (ldh), alanine aminotransferase (alt) and aspartate aminotransferase (ast) leakage were measured, as indicators of hepatic damage, at 1, 15 and 30 min of exposure to cm. |
2004-12-10 |
2023-08-12 |
rat |
| Mehmet Emin Büyükokuroğlu, Seyithan Taysi, Mustafa Buyukavci, Ebubekir Baka. Prevention of acute adriamycin cardiotoxicity by dantrolene in rats. Human & experimental toxicology. vol 23. issue 5. 2004-12-07. PMID:15222403. |
forty-eight hours after adr administration, biochemical changes including the activities of serum creatine kinase isoenzyme (ck-mb), lactate dehydrogenase (ldh) and aspartate aminotransferase (ast) and the levels of malondialdehyde (mda), superoxide dismutase (sod) and glutathione peroxidase (gsh-px) in heart tissue were measured. |
2004-12-07 |
2023-08-12 |
rat |
| V Sureshkumar, K V Venkateswaran, S Jayasunda. Interaction between enrofloxacin and monensin in broiler chickens. Veterinary and human toxicology. vol 46. issue 5. 2004-12-07. PMID:15487643. |
aspartate amino transferase (ast) significantly increased on the 6th d post enrofloxacin treatment. |
2004-12-07 |
2023-08-12 |
Not clear |
| Jason Evans, Donald Levesque, G Diane Shelto. Canine inflammatory myopathies: a clinicopathologic review of 200 cases. Journal of veterinary internal medicine. vol 18. issue 5. 2004-12-07. PMID:15515585. |
average creatine kinase (ck) and aspartate aminotransferase (ast) concentrations in gims were significantly higher than those with fims (p < .05). |
2004-12-07 |
2023-08-12 |
Not clear |
| Yi-Chao Hsu, Yung-Tsung Chiu, Chang-Yin Lee, Yun-Lian Lin, Yi-Tsau Huan. Increases in fibrosis-related gene transcripts in livers of dimethylnitrosamine-intoxicated rats. Journal of biomedical science. vol 11. issue 3. 2004-12-06. PMID:15067225. |
abnormal increases in plasma alanine transaminase (alt) and aspartate transaminase (ast) levels, plasma and mitochondrial mda levels, and portal venous pressure were also noted in dmn rats. |
2004-12-06 |
2023-08-12 |
rat |
| Federico Bertuzzi, Simona Marzorati, Paola Maffi, Lorenzo Piemonti, Raffaella Melzi, Francesca de Taddeo, Veronica Valtolina, Armando D'Angelo, Valerio di Carlo, Ezio Bonifacio, Antonio Secch. Tissue factor and CCL2/monocyte chemoattractant protein-1 released by human islets affect islet engraftment in type 1 diabetic recipients. The Journal of clinical endocrinology and metabolism. vol 89. issue 11. 2004-12-02. PMID:15531535. |
patients were monitored for their coagulation [cross-linked fibrin degradation products (xdps)] and liver function test [aspartate and alanine aminotransferase (ast and alt)] as markers of early posttransplant complications, and these were correlated with in vitro islet number, purification, volume, monocyte-chemoattractant protein-1 (ccl2/mcp-1) and tissue factor (tf) islet release. |
2004-12-02 |
2023-08-12 |
human |
| S M M Vasconcelos, R F Pereira, R S Alves, A C V Arruda Filho, L M V Aguiar, D S Macedo, R M Freitas, M G R Queiroz, F C F Sousa, G S B Vian. Effects of ethanol and haloperidol on plasma levels of hepatic enzymes, lipid profile, and apolipoprotein in rats. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 82. issue 2. 2004-11-24. PMID:15060626. |
results show increases in alanine transaminase (alt; 48% and 55%) and aspartate transaminase (ast; 32% and 22%) levels after ethanol or haloperidol (14 days) treatments, as compared with controls. |
2004-11-24 |
2023-08-12 |
rat |
| Sherif Y Saad, Tawfeeg A O Najjar, Mouied Alashar. Cardiotoxicity of doxorubicin/paclitaxel combination in rats: effect of sequence and timing of administration. Journal of biochemical and molecular toxicology. vol 18. issue 2. 2004-11-19. PMID:15122649. |
dox-induced cardiotoxicity was manifested by abnormal biochemical changes including marked increases in serum creatine phosphokinase isoenzyme (ck-mb), lactate dehydrogenase (ldh), glutathione peroxidase (gsh-px), and aspartate aminotransferase (ast) activity levels. |
2004-11-19 |
2023-08-12 |
rat |
| Anthony J G Hanley, Ken Williams, Andreas Festa, Lynne E Wagenknecht, Ralph B D'Agostino, Judy Kempf, Bernard Zinman, Steven M Haffne. Elevations in markers of liver injury and risk of type 2 diabetes: the insulin resistance atherosclerosis study. Diabetes. vol 53. issue 10. 2004-11-16. PMID:15448093. |
a limited number of studies have reported associations of markers of liver injury, including elevated concentrations of aspartate aminotransferase (ast) and alanine aminotransferase (alt), with prospective risk of type 2 diabetes. |
2004-11-16 |
2023-08-12 |
human |
| Aloísio Luiz Benedetti, Cidônia de Lourdes Vituri, Andréa Gonçalves Trentin, Maria Aparecida Custódio Domingues, Marcio Alvarez-Silv. The effects of sub-chronic exposure of Wistar rats to the herbicide Glyphosate-Biocarb. Toxicology letters. vol 153. issue 2. 2004-11-16. PMID:15451553. |
sub-chronic treatment of animals starting from the lowest dose of glyphosate induced the leakage of hepatic intracellular enzymes, alanine aminotransferase (alt) and aspartate aminotransferase (ast), suggesting irreversible damage in hepatocytes. |
2004-11-16 |
2023-08-12 |
rat |
| Viroj Wiwanitki. Activated partial thromboplastin time abnormality in patients with cholangiocarcinoma. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. vol 10. issue 1. 2004-11-09. PMID:14979409. |
the only two parameters that showed significant correlation are alanine aminotransferase (alt) and aspartate aminotransferase (ast) (p < 0.05). |
2004-11-09 |
2023-08-12 |
Not clear |
| K Kamashi, A Gopala Reddy, K S Reddy, V R Redd. Evaluation of zinc against salinomycin toxicity in broilers. Indian journal of physiology and pharmacology. vol 48. issue 1. 2004-10-18. PMID:15270374. |
the activity of glutathione peroxidase, glutathione reductase and catalase, and the values of aspartate aminotransferase (ast), alanine aminotransferase (alt), total proteins, total cholesterol, triglycerides, low density lipoproteins (ldl), urea, creatinine and blood urea nitrogen (bun) were significantly (p<0.01) elevated in toxic controls, whereas glutathione (gsh) and high density lipoproteins (hdl) were significantly (p<0.01) lowered as compared to group 1, 2, 4 and 5. |
2004-10-18 |
2023-08-12 |
Not clear |
| Hany Z Rofae. Effect of ketamine pretreatment on cocaine-mediated hepatotoxicity in rats. Toxicology letters. vol 152. issue 3. 2004-10-18. PMID:15331130. |
serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) were measured as markers of liver injury. |
2004-10-18 |
2023-08-12 |
rat |
| Saburo Murakami, Katsuhiko Okubo, Yoshitaka Tsuji, Hideto Sakata, Takehiro Takahashi, Masataka Kikuchi, Renzo Hirayam. Changes in liver enzymes after surgery in anti-hepatitis C virus-positive patients. World journal of surgery. vol 28. issue 7. 2004-10-14. PMID:15175902. |
serum levels of aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), lactate dehydrogenase (ldh), and cholinesterase (che) were the standard liver tests performed. |
2004-10-14 |
2023-08-12 |
Not clear |
| Victor de Lédinghen, Michel Combes, Hélène Trouette, Maria Winnock, Michel Amouretti, Antoine de Mascarel, Patrice Couzigo. Should a liver biopsy be done in patients with subclinical chronically elevated transaminases? European journal of gastroenterology & hepatology. vol 16. issue 9. 2004-10-12. PMID:15316412. |
significant differences were observed between f < 2 and f > or = 2 fibrosis patients for aspartate aminotransferase (ast) and alt and between patients with nash or without for body mass index. |
2004-10-12 |
2023-08-12 |
human |
| Sadakat Ozdil, Sehnaz Bolkent, Refiye Yanardag, Pelin Arda-Pirincc. Protective effects of ascorbic acid, dl-alpha-tocopherol acetate, and sodium selenate on ethanol-induced liver damage of rats. Biological trace element research. vol 97. issue 2. 2004-10-08. PMID:14985625. |
in the group administered ethanol, a reduction of the blood glutathione (gsh) level and increases in serum values of alanine aminotranserase (alt), aspartate aminotransferase (ast), lactate dehydrogenase (ldh), alkaline phosphatase (alp), and gamma-glutamyl transferase (ggt) activities were observed, whereas in the control group, the reverse was found to occur. |
2004-10-08 |
2023-08-12 |
rat |