| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yen-Hung Yeh, You-Liang Hsieh, Ya-Ting Le. Effects of yam peel extract against carbon tetrachloride-induced hepatotoxicity in rats. Journal of agricultural and food chemistry. vol 61. issue 30. 2014-01-10. PMID:23841820. |
yam peel extract for 8 weeks significantly reduced the impact of ccl4 toxicity on the serum markers of liver damage, aspartate aminotransferase (ast), alanine aminotransferase (alt), and alkaline phosphatase (alp). |
2014-01-10 |
2023-08-12 |
rat |
| Max M Gong, Brendan D Macdonald, Trung Vu Nguyen, Kinh Van Nguyen, David Sinto. Field tested milliliter-scale blood filtration device for point-of-care applications. Biomicrofluidics. vol 7. issue 4. 2014-01-09. PMID:24404044. |
biochemistry and immunology testing establish the suitability of the device as a sample preparation unit for testing alanine transaminase (alt), aspartate transaminase (ast), urea, hepatitis b "e" antigen (hbeag), hepatitis b "e" antibody (hbe ab), and hepatitis b surface antibody (hbs ab). |
2014-01-09 |
2023-08-12 |
human |
| Bilge Depboylu, Murat Giriş, Vakur Olgaç, Semra Doğru-Abbasoğlu, Müjdat Uysa. Response of liver to lipopolysaccharide treatment in male and female rats. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 65. issue 5. 2014-01-07. PMID:22884257. |
hepatic histopathology and serum alanine transaminase (alt) and aspartate transaminase (ast) activities were also investigated. |
2014-01-07 |
2023-08-12 |
rat |
| Jing Zhang, Shaoping Lu, Haiyan Wang, Qiangsun Zhen. Protective role of Aralia elata polysaccharide on mercury(II)-induced cardiovascular oxidative injury in rats. International journal of biological macromolecules. vol 59. 2014-01-07. PMID:23612361. |
in addition, elevated serum aspartate aminotransferase (ast), alanine aminotransferase (alt), blood urea nitrogen (bun) and creatinine (cr) levels in the saline-treated hg group were also reversed by aep-w1 treatment. |
2014-01-07 |
2023-08-12 |
mouse |
| Li-Na Zhang, Pan-Pan Liu, Lingyan Wang, Fang Yuan, Leiting Xu, Yanfei Xin, Li-Juan Fei, Qi-Long Zhong, Yi Huang, Limin Xu, Ling-Mei Hao, Xu-Jun Qiu, Yanping Le, Meng Ye, Shiwei Dua. Lower ADD1 gene promoter DNA methylation increases the risk of essential hypertension. PloS one. vol 8. issue 5. 2014-01-07. PMID:23691048. |
in addition, significant differences were observed between males and females for alanine aminotransferase (alt, p = 0.001), aspartate aminotransferase (ast, p = 0.005) and uric acid (p<0.001). |
2014-01-07 |
2023-08-12 |
Not clear |
| Om Parkash, Adil Ayub, Wasim Jafri, Syed Hasnain Alishah, Saeed Hami. Wilson's disease: Experience at a tertiary care hospital. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP. vol 23. issue 7. 2014-01-07. PMID:23823966. |
mean serum aspartate transaminase (ast) / alanine transaminases (alt) ratio was 1.92 and median alkaline phosphatase / total bilirubin ratio was 79.30 (iqr 35.05; 166.50). |
2014-01-07 |
2023-08-12 |
Not clear |
| Xiaomei Xu, Yan Hu, Xiaohan Zhai, Musen Lin, Zhao Chen, Xiaofeng Tian, Feng Zhang, Dongyan Gao, Xiaochi Ma, Li Lv, Jihong Ya. Salvianolic acid A preconditioning confers protection against concanavalin A-induced liver injury through SIRT1-mediated repression of p66shc in mice. Toxicology and applied pharmacology. vol 273. issue 1. 2014-01-06. PMID:23993977. |
the results showed that in vivo pretreatment with sala significantly reduced cona-induced elevation in serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities and decreased levels of the hepatotoxic cytokines such as interferon-gamma (ifn-γ) and tumor necrosis factor-alpha (tnf-α). |
2014-01-06 |
2023-08-12 |
mouse |
| Norhaizan Mohd Esa, Khairul-Kamilah Abdul Kadir, Zulkhairi Amom, Azrina Azla. Antioxidant activity of white rice, brown rice and germinated brown rice (in vivo and in vitro) and the effects on lipid peroxidation and liver enzymes in hyperlipidaemic rabbits. Food chemistry. vol 141. issue 2. 2014-01-03. PMID:23790918. |
the reduction of lipid peroxidation levels and activity of hepatic enzymes (alanine transferase, alt and aspartate transaminase, ast) were only significantly observed in the gbr group. |
2014-01-03 |
2023-08-12 |
rabbit |
| Chia-Chen Lee, Siou-Ru Shen, Ying-Jang Lai, She-Ching W. Rutin and quercetin, bioactive compounds from tartary buckwheat, prevent liver inflammatory injury. Food & function. vol 4. issue 5. 2014-01-02. PMID:23584161. |
eeb inhibited increase in serum aspartate transaminase (ast), alanine transaminase (alt) and alkaline phosphatase (alp) levels in the ethanol- and ccl(4)-induced animals; similar effects were found after rutin and quercetin administration. |
2014-01-02 |
2023-08-12 |
mouse |
| Maha M A Basyoni, Abdel-Aleem A El-Saba. Therapeutic potential of myrrh and ivermectin against experimental Trichinella spiralis infection in mice. The Korean journal of parasitology. vol 51. issue 3. 2014-01-02. PMID:23864740. |
serum aspartate aminotransferase (ast), alanine aminotransferase (alt), total protein, albumin, globulin, urea, and creatinine values were estimated. |
2014-01-02 |
2023-08-12 |
mouse |
| Temitayo Olabisi Ajibade, Ruben Arowolo, Funsho Olakitike Olayem. Phytochemical screening and toxicity studies on the methanol extract of the seeds of moringa oleifera. Journal of complementary & integrative medicine. vol 10. 2013-12-31. PMID:23652639. |
sub-acute administration of the seed extract caused significant (p<0.05) increase in the levels of alanine and aspartate transferases (alt and ast), and significant (p<0.05) decrease in weight of experimental rats, at 1,600 mg kg-1. |
2013-12-31 |
2023-08-12 |
rat |
| Wei-Xi Li, Yi-Fang Li, Yu-Jia Zhai, Wei-Min Chen, Hiroshi Kurihara, Rong-Rong H. Theacrine, a purine alkaloid obtained from Camellia assamica var. kucha, attenuates restraint stress-provoked liver damage in mice. Journal of agricultural and food chemistry. vol 61. issue 26. 2013-12-31. PMID:23678853. |
results showed that 18 h of restraint stress could induce liver damage, with an obvious increase in levels of plasma alanine aminotransferase (alt) and aspartate aminotransferase (ast). |
2013-12-31 |
2023-08-12 |
mouse |
| M Hüttemann, M Shipkova, C Klett, G Hasche, J Wilhelm, R Bolley, C Olbricht, E Wielan. Total and free plasma concentrations of the active metabolite of leflunomide in relation to therapeutic outcome in kidney transplant recipients with BK-virus nephropathy. Transplantation proceedings. vol 45. issue 4. 2013-12-30. PMID:23726631. |
to detect toxicity, we recorded blood and platelet counts, hematocrit, hemoglobin concentrations, liver enzymes (alanine aminotransferase [alt], and aspartate aminotransferase [ast]), and skin diseases. |
2013-12-30 |
2023-08-12 |
Not clear |
| Daniela Luiza Baconi, Maria Bârcă, Gina Manda, Anne Marie Ciobanu, C Bălălă. Investigation of the toxicity of some organophosphorus pesticides in a repeated dose study in rats. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. vol 54. issue 2. 2013-12-27. PMID:23771080. |
body and organs weights, plasma and brain cholinesterase activities, serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) activities, histopathological changes in liver and kidney, and some parameters of the immune function, such as leukocyte formula, spleen weight and cellularity, spleen lymphocytes proliferation in response to concanavalin a (con a) were investigated; the potential oxidative stress (malondialdehyde in plasma and brain, and blood catalase activity) was also evaluated. |
2013-12-27 |
2023-08-12 |
rat |
| M A Gbadegesin, O A Odunol. Aqueous and ethanolic leaf extracts of Ocimum basilicum (sweet basil) protect against sodium arsenite-induced hepatotoxicity in Wistar rats. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria. vol 25. issue 1. 2013-12-26. PMID:22314900. |
in addition, treatments of the animals with aqueous or ethanolic extract of o. basilicum before the administration of sodium arsenite resulted in the attenuation of the sodium arsenite-induced aspartate and alanine aminotransferase activities: alt (from 282.6% to 167.7% and 157.8%), ast (from 325.1% to 173.5% and 164.2%) for the group administered sodium arsenite alone, the aqueous extracts plus sodium arsenite, and ethanolic extracts plus sodium arsenite respectively, expressed as percentage of the negative control. |
2013-12-26 |
2023-08-12 |
rat |
| Jian-Yin Zhou, Zhen-Yu Yin, Sheng-Yu Wang, Jiang-Hua Yan, Yi-Lin Zhao, Duan Wu, Zheng-Jin Liu, Sheng Zhang, Xiao-Min Wan. [Influence of bear bile on rat hepatocarcinoma induced by diethylnitrosamine]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 47. issue 11. 2013-12-23. PMID:23387081. |
after 18 weeks the activities of serum alanine transaminase (alt), aspartate transaminase (ast) and total bilirubin (tbil) were detected. |
2013-12-23 |
2023-08-12 |
rat |
| S Dalaklioglu, G E Genc, N H Aksoy, F Akcit, S Gumusl. Resveratrol ameliorates methotrexate-induced hepatotoxicity in rats via inhibition of lipid peroxidation. Human & experimental toxicology. vol 32. issue 6. 2013-12-23. PMID:23424212. |
aspartate aminotransferase (ast), alanine aminotransferase (alt), and alkaline phosphatase (alp) were used as biochemical markers of mtx-induced hepatic injury. |
2013-12-23 |
2023-08-12 |
rat |
| Nasrin Aghel, Heibatollah Kalantari, Shohreh Rezazade. Hepatoprotective Effect of Ficus carica Leaf Extract on Mice Intoxicated with Carbon Tetrachloride. Iranian journal of pharmaceutical research : IJPR. vol 10. issue 1. 2013-12-23. PMID:24363682. |
levels of marker enzymes such as alanine aminotransferase (alt) and aspartate aminotransferase (ast) were increased significantly in ccl4 treated mice (group iii). |
2013-12-23 |
2023-08-12 |
mouse |
| L Pozzo, G Salamano, E Mellia, M S Gennero, L Doglione, L Cavallarin, M Tarantola, G Forneris, A Schiavon. Feeding a diet contaminated with ochratoxin A for chickens at the maximum level recommended by the EU for poultry feeds (0.1 mg/kg). 1. Effects on growth and slaughter performance, haematological and serum traits. Journal of animal physiology and animal nutrition. vol 97 Suppl 1. 2013-12-18. PMID:23639013. |
liver enzymes (alanino aminotransferase, alt and aspartate aminotransferase, ast) and kidney function parameters (uric acid and creatinine) were quantified. |
2013-12-18 |
2023-08-12 |
Not clear |
| Eun Young Park, Min Kyung Lim, Jin-Kyoung Oh, Heeyoun Cho, Mi Jin Bae, E Hwa Yun, Dong-il Kim, Hai-Rim Shi. Independent and supra-additive effects of alcohol consumption, cigarette smoking, and metabolic syndrome on the elevation of serum liver enzyme levels. PloS one. vol 8. issue 5. 2013-12-17. PMID:23667618. |
information on alcohol consumption, smoking status, and metabolic syndrome, defined as per the criteria of the adult treatment panel iii, were applied to evaluate their impact on serum levels of aspartate aminotransferase (ast), alanine aminotransferase (alt), and gamma-glutamyl transferase (ggt). |
2013-12-17 |
2023-08-12 |
human |