| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Oluwatosin Adekunle Adaramoye, Olubukola Oyebimpe Akann. Effects of Methanol Extract of Breadfruit (Artocarpus altilis) on Atherogenic Indices and Redox Status of Cellular System of Hypercholesterolemic Male Rats. Advances in pharmacological sciences. vol 2014. 2014-03-04. PMID:24592277. |
biochemical indices such as total cholesterol (tc), triglycerides (tg), low- and high-density lipoproteins-cholesterol (ldl-c and hdl-c), aspartate and alanine aminotransferases (ast and alt), lactate dehydrogenase (ldh), reduced glutathione, glutathione-s-transferase, glutathione peroxidase (gpx), catalase (cat), superoxide dismutase (sod), and lipid peroxidation (lpo) were assessed. |
2014-03-04 |
2023-08-12 |
rat |
| Amal S Abdel-Azeem, Amany M Hegazy, Khadiga S Ibrahim, Abdel-Razik H Farrag, Eman M El-Saye. Hepatoprotective, antioxidant, and ameliorative effects of ginger (Zingiber officinale Roscoe) and vitamin E in acetaminophen treated rats. Journal of dietary supplements. vol 10. issue 3. 2014-03-03. PMID:23927622. |
administration of apap elicited significant liver injury that was manifested by remarkable increase in plasma alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), arginase activities, and total bilirubin concentration. |
2014-03-03 |
2023-08-12 |
rat |
| Swapna Sirasanagandla, Ramesh Babu Kasetti, Abdul Nabi Shaik, Rajesh Natava, Venkata Prasad Surtineni, Suresh Reddy Cirradur, Apparao Chippad. Antihyperglycemic and antihyperlipidemic activities of 2-(4-[(2-hydroxybenzyl) amino]-phenyl amino-methyl)-phenol in STZ induced diabetic rats. European journal of medicinal chemistry. vol 66. 2014-02-28. PMID:23827180. |
activities of serum aspartate transaminase (ast), alanine transaminase (alt) and alkaline phosphatase (alp) and levels of blood urea and creatinine were improved to near normal levels in the treated stz rats indicating the protective role of the hbpmp against liver and kidney damage and its non-toxic property. |
2014-02-28 |
2023-08-12 |
rat |
| Zhaofa Li, Xiaoying Deng, Jiajia Xu, Wenchang Lia. [Protective effects of PEG modified recombinant cytoglobin on acute liver injury in mice]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology. vol 28. issue 10. 2014-02-27. PMID:23311137. |
the results showed that peg-rcygb reduced the liver mass index and decreased significantly the levels of alanine amiotransferase (ast) and aspartate transaminase (alt) in mouse serum. |
2014-02-27 |
2023-08-12 |
mouse |
| Nantiga Virgona, Yuko Taki, Shizuo Yamada, Keizo Umegak. Dietary Coleus forskohlii extract generates dose-related hepatotoxicity in mice. Journal of applied toxicology : JAT. vol 33. issue 9. 2014-02-25. PMID:22729658. |
food intake, body weights, relative organ weights and liver marker enzymes [aspartate aminotransferase (ast), alanine aminotransferase (alt), and alkaline phosphatase (alp)] combined with histophatological analysis were assessed. |
2014-02-25 |
2023-08-12 |
mouse |
| Shailendra Pratap Singh, Monika Kumari, Srinivas I Kumari, Mohammed F Rahman, M Mahboob, Paramjit Grove. Toxicity assessment of manganese oxide micro and nanoparticles in Wistar rats after 28 days of repeated oral exposure. Journal of applied toxicology : JAT. vol 33. issue 10. 2014-02-25. PMID:23702825. |
significant changes were observed in aspartate aminotransferase (ast), alanine aminotransferase (alt) and lactate dehydrogenase (ldh) in the liver, kidney and serum in a dose-dependent manner. |
2014-02-25 |
2023-08-12 |
rat |
| Ya-Ling Chen, Hsiang-Chi Peng, Shan-Wen Tan, Cheng-Yuh Tsai, Yi-Huei Huang, Hao-Yu Wu, Suh-Ching Yan. Amelioration of ethanol-induced liver injury in rats by nanogold flakes. Alcohol (Fayetteville, N.Y.). vol 47. issue 6. 2014-02-24. PMID:23830375. |
after 10 weeks, rats in group e showed significantly higher plasma aspartate transaminase (ast) and alanine transaminase (alt) activities than those in group c. a significantly increased concentration of hepatic triglyceride (tg) was found in group e. furthermore, higher hepatic glutathione reductase (grd), superoxide dismutase (sod), and catalase (cat) activities together with higher tumor necrosis factor (tnf)-α concentration and higher hepatic cytochrome (cyp2e1) protein expression were also observed in group e. in contrast, the hepatic tg concentration in group ehf was significantly lower than that of group e. in addition, hepatic glutathione peroxidase (gpx), sod, and cat activities together with tnf-α concentration and hepatic cyp2e1 protein expression in group ehf were significantly lower than those in group e. we concluded that nanogold flakes might ameliorate alcohol-induced liver injury by maintaining the hepatic antioxidative status. |
2014-02-24 |
2023-08-12 |
rat |
| H N Mustafa, Sally A El Awdan, Gehan A Hegaz. Protective role of antioxidants on thioacetamide-induced acute hepatic encephalopathy: biochemical and ultrastructural study. Tissue & cell. vol 45. issue 5. 2014-02-24. PMID:23876406. |
blood samples were collected and serum was obtained for analysis of aspartate aminotransferase (ast), alanine aminotransferase (alt), gamma-glutamyl transferase (ggt), total protein, triglyceride, cholesterol using spectrophotometer and elisa kits. |
2014-02-24 |
2023-08-12 |
rat |
| Lukas Kalinke, Mohammed Rashi. A cholestatic diagnostic dilemma. BMJ case reports. vol 2013. 2014-02-20. PMID:23632607. |
he had severe, mainly conjugated (642 μmol/l), hyperbilirubinaemia (1033 μmol/l), with elevated liver enzymes: alkaline phosphatase (alp) (163 iu/l), γ-glutamyltransferase (ggt) (277 iu/l) and aspartate transaminase (ast) (358 iu/l). |
2014-02-20 |
2023-08-12 |
Not clear |
| Kunnathur Murugesan Sakthivel, Chandrasekaran Guruvayoorappa. Acacia ferruginea inhibits tumor progression by regulating inflammatory mediators-(TNF-a, iNOS, COX-2, IL-1β, IL-6, IFN-γ, IL-2, GM-CSF) and pro-angiogenic growth factor- VEGF. Asian Pacific journal of cancer prevention : APJCP. vol 14. issue 6. 2014-02-19. PMID:23886206. |
treatment with extract significantly increased the life span, total white blood cell (wbc) count and haemoglobin (hb) content and decreased the level of serum aspartate transaminase (ast), alanine transaminase (alt), alkaline phosphatase (alp), gamma glutamyl transferase (γ-gt) and nitric oxide (no) in dla bearing ascites tumor models. |
2014-02-19 |
2023-08-12 |
mouse |
| D Magistrelli, A A Aufy, L Pinotti, F Ros. Analysis of weaning-induced stress in Saanen goat kids. Journal of animal physiology and animal nutrition. vol 97. issue 4. 2014-02-18. PMID:22715986. |
during the last week, fasting plasma cortisol level was significantly lower, whereas plasma activity of both alanine aminotransferase (alt) and aspartate aminotransferase (ast) was significantly higher in wmix kids, in relation to the milk ones. |
2014-02-18 |
2023-08-12 |
Not clear |
| Y A Attia, H F Allakany, A E Abd Al-Hamid, A A Al-Saffar, R A Hassan, N A Mohame. Capability of different non-nutritive feed additives on improving productive and physiological traits of broiler chicks fed diets with or without aflatoxin during the first 3 weeks of life. Journal of animal physiology and animal nutrition. vol 97. issue 4. 2014-02-18. PMID:23050696. |
aflatoxin significantly increased percentage liver, lymphocyte (%), monocyte (%), serum triglyceride level, and the aspartate aminotransferase (ast), and alanine aminotransferase (alt), concentrations while decreasing dressing percentage, intestinal percentage, white blood cells (wbcs), red blood cells (rbcs), haemoglobin (hgb), packed cell volume (pcv), heterophil (%), heterophil/lymphocyte ratio, total serum protein and serum albumin. |
2014-02-18 |
2023-08-12 |
Not clear |
| San-Qiang Li, Dong-Mei Wang, You-Ju Shu, Xue-Dong Wan, Zheng-Shun Xu, En-Zhong L. Proper heat shock pretreatment reduces acute liver injury induced by carbon tetrachloride and accelerates liver repair in mice. Journal of toxicologic pathology. vol 26. issue 4. 2014-02-14. PMID:24526809. |
hematoxylin and eosin (h&e) staining, serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels and the expression levels of heat shock protein 70 (hsp70), cytochrome p450 1a2 (cyp1a2) and proliferating cell nuclear antigen (pcna) were detected in the unheated control mice and heat shock-pretreated mice after ccl4 administration. |
2014-02-14 |
2023-08-12 |
mouse |
| Hirofumi Inoue, Mari Maeda-Yamamoto, Atsushi Nesumi, Takuji Tanaka, Akira Murakam. Low and medium but not high doses of green tea polyphenols ameliorated dextran sodium sulfate-induced hepatotoxicity and nephrotoxicity. Bioscience, biotechnology, and biochemistry. vol 77. issue 6. 2014-02-13. PMID:23748761. |
gtps at 0.01% and 0.1% significantly suppressed dss-increased serum aspartate 2-oxoglutarate aminotransferase (ast) and alanine aminotransferase (alt) levels. |
2014-02-13 |
2023-08-12 |
mouse |
| Mohammad Hashemnia, Azizollah Khodakaram-Tafti, Seyed Mostafa Razavi, Saeed Nazif. Hematological and serum biochemical analyses in experimental caprine coccidiosis. Journal of parasitic diseases : official organ of the Indian Society for Parasitology. vol 38. issue 1. 2014-02-07. PMID:24505189. |
serum biochemical parameters including total protein (tp), albumin, chloride (cl(-)), sodium (na(+)), potassium (k(+)), aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), and gamma glutamyltransferase (ggt) were measured. |
2014-02-07 |
2023-08-12 |
Not clear |
| Lulu Zhang, Enting Wang, Feng Chen, Haiyang Yan, Yuan Yua. Potential protective effects of oral administration of allicin on acrylamide-induced toxicity in male mice. Food & function. vol 4. issue 8. 2014-02-06. PMID:23760623. |
furthermore, oral administration of allicin not only significantly decreased aspartate aminotransferase (ast), alanine aminotransferase (alt), lactate dehydrogenase (ldh), blood urea nitrogen (bun), tumor necrosis factor α (tnf-α), interleukin (il)-1β, interleukin (il)-6, reactive oxygen species (ros), and 8-hydroxy-desoxyguanosine (8-ohdg), but also increased interleukin (il)-10 in the serum of aa-treated mice. |
2014-02-06 |
2023-08-12 |
mouse |
| Li-Yun Zheng, Li-Min Zang, Qing-Hua Yang, Wen-Quan Yu, Xian-Zhen Fang, Yu-Hai Zhang, Xue-Jie Zhao, Na Wan, Yue-Teng Zhang, Qing-Duan Wang, Jun-Biao Chan. Anti-hepatitis B virus activity of α-DDB-DU, a novel nucleoside analogue, in vitro and in vivo. European journal of pharmacology. vol 702. issue 1-3. 2014-02-04. PMID:23415746. |
furthermore, the levels of alanine transaminase (alt) and aspartate aminotransferase (ast) in both serum and livers were notably reduced on day 10 and histopathological evaluation of the animals' livers indicated significant improvement. |
2014-02-04 |
2023-08-12 |
human |
| Margret Rave-Fränk, Ihtzaz Ahmed Malik, Hans Christiansen, Naila Naz, Sadaf Sultan, Ahmad Amanzada, Martina Blaschke, Silke Cameron, Shakil Ahmad, Clemens Friedrich Hess, Giuliano Ramadori, Federico Moricon. Rat model of fractionated (2 Gy/day) 60 Gy irradiation of the liver: long-term effects. Radiation and environmental biophysics. vol 52. issue 3. 2014-02-04. PMID:23595725. |
serum levels indicative of liver damage were determined for alkaline phosphatase (ap), aspartate aminotransferase (ast), alanine aminotransferase (alt), gamma-glutamyltransferase (γgt) and lactate dehydrogenase (ldh). |
2014-02-04 |
2023-08-12 |
rat |
| Rong Li, Tao Liang, Qiaoling He, Chao Guo, Lingyuan Xu, Kefeng Zhang, Xiaoqun Dua. Puerarin, isolated from Kudzu root (Willd.), attenuates hepatocellular cytotoxicity and regulates the GSK-3β/NF-κB pathway for exerting the hepatoprotection against chronic alcohol-induced liver injury in rats. International immunopharmacology. vol 17. issue 1. 2014-02-03. PMID:23751897. |
the results indicated that serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp) and pro-inflammatory cytokines were significantly reduced following pr treatment, while the albumin (alb) level was increased. |
2014-02-03 |
2023-08-12 |
rat |
| Guan-Jhong Huang, Jeng-Shyan Deng, Shyh-Shyun Huang, Chao-Ying Lee, Wen-Chi Hou, Sheng-Yang Wang, Ping-Jyun Sung, Yueh-Hsiung Ku. Hepatoprotective effects of eburicoic acid and dehydroeburicoic acid from Antrodia camphorata in a mouse model of acute hepatic injury. Food chemistry. vol 141. issue 3. 2014-01-31. PMID:23871054. |
pretreatment with tr1 and tr2 prevented the elevation of aspartate aminotransferase (ast), alanine aminotransferase (alt), and liver lipid peroxides in ccl4-treated mice. |
2014-01-31 |
2023-08-12 |
mouse |