| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Malachy N O Ajima, Ogo A Ogo, Bala S Audu, Kyrian C Ugwoegb. Chronic diclofenac (DCF) exposure alters both enzymatic and haematological profile of African catfish, Clarias gariepinus. Drug and chemical toxicology. vol 38. issue 4. 2016-07-19. PMID:25367777. |
furthermore, the levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), lactate dehydrogenase (ldh) and glucose values significantly increased while protein levels were reduced (p < 0.05) in serum and gills throughout the 42-day exposure period. |
2016-07-19 |
2023-08-13 |
human |
| Chong Wan, Rui Han, Limin Liu, Fang Zhang, Fang Li, Mingdeng Xiang, Wenjun Din. Role of miR-155 in fluorooctane sulfonate-induced oxidative hepatic damage via the Nrf2-dependent pathway. Toxicology and applied pharmacology. vol 295. 2016-07-19. PMID:26844784. |
we found that pfos significantly increased the liver weight and serum alanine transaminase (alt) and aspartate amino transferase (ast) levels in rats. |
2016-07-19 |
2023-08-13 |
rat |
| Wun-Hong Liang, Chien-Hung Chu, Ruey-Jen Yan. Bio-sample detection on paper-based devices with inkjet printer-sprayed reagents. Talanta. vol 145. 2016-07-18. PMID:26459437. |
the feasibility of the proposed method is demonstrated by performing aspartate aminotransferase (ast) and alanine aminotransferase (alt) tests using simple two-dimensional (2d) paper-based devices. |
2016-07-18 |
2023-08-13 |
Not clear |
| Yoshiyuki Inoue, Yujiro Hayashi, Kenji Kangawa, Yoshihiro Suzuki, Noboru Murakami, Keiko Nakahar. Des-acyl ghrelin prevents heatstroke-like symptoms in rats exposed to high temperature and high humidity. Neuroscience letters. vol 615. 2016-07-14. PMID:26773867. |
although biochemical analysis revealed that exposure to high temperature significantly increased hematocrit and the serum levels of aspartate amino transferase (ast), alanine transaminase (alt), blood urea nitrogen (bun), creatinine and electrolytes (na(+), k(+), cl(-)), most of these heatstroke-associated reactions were significantly reduced by treatment with des-acyl ghrelin. |
2016-07-14 |
2023-08-13 |
rat |
| Frederico Luis Rosa-Lima, Luiz Lannes, Diego Viana-Gomes, Anna Paola T R Pierucci, Verônica P Salern. Protein carbonyl levels correlate with performance in elite field hockey players. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. vol 40. issue 7. 2016-07-11. PMID:25962716. |
for biomarkers of tissue damage, creatine kinase and aspartate transaminase (ast) increased postgame by 150% and 75%, respectively. |
2016-07-11 |
2023-08-13 |
Not clear |
| Hazuki Tamada, Hisao Naito, Kazuya Kitamori, Yumi Hayashi, Nozomi Yamagishi, Masashi Kato, Tamie Nakajim. Efficacy of Dietary Lipid Control in Healing High-Fat and High-Cholesterol Diet-Induced Fibrotic Steatohepatitis in Rats. PloS one. vol 11. issue 1. 2016-07-08. PMID:26727365. |
dietary intervention before the appearance of fibrosis significantly improved the steatosis and reset the increased serum aspartate aminotransferase (ast), alanine aminotransferase (alt), and serum total cholesterol (tc) levels. |
2016-07-08 |
2023-08-13 |
rat |
| A Goringe, A Al-Sabah, H Dasan. A lesson from persistently elevated aspartate transaminases (AST) in a patient with severe haemophilia A. Haemophilia : the official journal of the World Federation of Hemophilia. vol 2. issue 2. 2016-07-07. PMID:27214019. |
a lesson from persistently elevated aspartate transaminases (ast) in a patient with severe haemophilia a. |
2016-07-07 |
2023-08-13 |
Not clear |
| Mehjbeen Javed, Irshad Ahmad, Ajaz Ahmad, Nazura Usmani, Masood Ahma. Studies on the alterations in haematological indices, micronuclei induction and pathological marker enzyme activities in Channa punctatus (spotted snakehead) perciformes, channidae exposed to thermal power plant effluent. SpringerPlus. vol 5. issue 1. 2016-07-07. PMID:27386247. |
the present study was conducted to assess the toxicity of thermal power plant effluent containing heavy metals (fe > cu > zn > mn > ni > co > cr) on haematological indices, micronuclei, lobed nuclei and activity of pathological marker enzymes [alkaline phosphatase (alp), aspartate transferase (ast), alanine transferase (alt) and creatine kinase (ck)] in channa punctatus. |
2016-07-07 |
2023-08-13 |
Not clear |
| Huafeng Zou, Xianshou Bai, Yuhong Feng, Ying Zhang, Youji Wang, Weiqun L. Influence of long (16L:8D) and short (8L:16D) photoperiods on blood metabolites and hepatic metabolism in Olive flounder, Paralichthys olivaceus. SpringerPlus. vol 5. issue 1. 2016-07-07. PMID:27386368. |
alkaline phosphatase (alp), alanine aminotransferase (alt) and aspartate aminotransferase (ast) enzyme activities in plasma also increased in lp flounder. |
2016-07-07 |
2023-08-13 |
Not clear |
| Yao Xue Guo, Xue Fei Xu, Qi Zhi Zhang, Chun Li, Ye Deng, Pei Jiang, Lei Yan He, Wen Xing Pen. The inhibition of hepatic bile acids transporters Ntcp and Bsep is involved in the pathogenesis of isoniazid/rifampicin-induced hepatotoxicity. Toxicology mechanisms and methods. vol 25. issue 5. 2016-07-06. PMID:25886055. |
the hepatoxic effect was also indicated by increased serum biomarkers, such as aspartate transaminase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), direct bilirubin (dbil), total bilirubin (tbil) and total bile acids (tba). |
2016-07-06 |
2023-08-13 |
mouse |
| Geok Soon Lim, Joseph S Chang, Zhang Lei, Ruige Wu, Zhiping Wang, Kemi Cui, Stephen Won. A lab-on-a-chip system integrating tissue sample preparation and multiplex RT-qPCR for gene expression analysis in point-of-care hepatotoxicity assessment. Lab on a chip. vol 15. issue 20. 2016-07-06. PMID:26329655. |
to demonstrate the efficacy of our loc system for poct hepatotoxicity assessment, we perform a preclinical animal study with the administration of cyclophosphamide, followed by gene expression analysis of two critical protein biomarkers for liver function tests, aspartate transaminase (ast) and alanine transaminase (alt). |
2016-07-06 |
2023-08-13 |
Not clear |
| S I Park, J H Lee, H J Ham, Y J Jung, M S Park, J Lee, L S Maeng, Y A Chung, K S Jan. Evaluation of 2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography in rat models with hepatocellular carcinoma with liver cirrhosis. Bio-medical materials and engineering. vol 26 Suppl 1. 2016-07-06. PMID:26405933. |
the serum levels of alanine transaminase (alt), aspartate transaminase (ast), and alkaline phosphate (alp) were significantly higher at zero weeks after the last den injection. |
2016-07-06 |
2023-08-13 |
rat |
| Seung Hwa Lee, Kyu Nam Kim, Kwang Min Kim, Nam Seok Jo. Irritable Bowel Syndrome May Be Associated with Elevated Alanine Aminotransferase and Metabolic Syndrome. Yonsei medical journal. vol 57. issue 1. 2016-07-06. PMID:26632395. |
the aim of this study was to examine whether ibs was associated with elevated hepatic enzyme [alanine aminotransferase (alt) and aspartate aminotransferase (ast)], gamma-glutamyl transferase (γ-gt) levels, and metabolic syndrome (ms). |
2016-07-06 |
2023-08-13 |
Not clear |
| Emad A Hashish, Shimaa A Elgam. Hepatoprotective and Nephroprotective Effect of Curcumin Against Copper Toxicity in Rats. Indian journal of clinical biochemistry : IJCB. vol 31. issue 3. 2016-07-06. PMID:27382197. |
changes were observed in hepatic marker enzymes such as: aspartate aminotransferase (ast), alanine transaminase-(alt), alkaline phosphatase (alp) and gamma-glutamyltransferase (ggt), besides the serum total protein, urea and creatinine. |
2016-07-06 |
2023-08-13 |
rat |
| Imen Flehi-Slim, Issam Chargui, Sonia Boughattas, Aymen El Mabrouk, Yosra Belaïd-Nouira, Fadwa Neffati, Mohamed Fadhel Najjar, Zohra Haouas, Hassen Ben Cheik. Malathion-induced hepatotoxicity in male Wistar rats: biochemical and histopathological studies. Environmental science and pollution research international. vol 22. issue 22. 2016-07-01. PMID:26162445. |
biochemical parameters showed that alanine transaminase (alt), aspartate transaminase (ast), gamma glutamyl transpeptidase (ggt), lactate dehydrogenase (ldh), and alkaline phosphatase (alp) levels increased in the treated groups when the level of total protein decreased in intoxicated groups. |
2016-07-01 |
2023-08-13 |
rat |
| Abbas Ali Zeraati, Fatemeh Nazemian, Ladan Takalloo, Amirhossein Sahebkar, Elahe Heidari, Mohammad Ali Yaghoub. The relationship between serology of hepatitis E virus with liver and kidney function in kidney transplant patients. EXCLI journal. vol 15. 2016-07-01. PMID:27366144. |
in this study, 110 patients with kidney transplantation were recruited, and anti-hev igg, creatinine, alanine transaminase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), and estimated glomerular filtration rate (egfr) in the first, third and sixth months after renal transplantation were measured. |
2016-07-01 |
2023-08-13 |
human |
| Zhongji Meng, Xiaoyong Zhang, Rongjuan Pei, Ejuan Zhang, Thekla Kemper, Jörg Vollmer, Heather L Davis, Dieter Glebe, Wolfram Gerlich, Michael Roggendorf, Mengji L. Combination therapy including CpG oligodeoxynucleotides and entecavir induces early viral response and enhanced inhibition of viral replication in a woodchuck model of chronic hepadnaviral infection. Antiviral research. vol 125. 2016-06-30. PMID:26585244. |
significantly elevated levels of serum aspartate aminotransferase (ast) but not of alanine aminotransferase (alt) in some of the woodchucks receiving cpg odn were noted, but these increases were resolved before the completion of treatment and were not associated with an elevated serum bilirubin level or coagulation disorders, suggesting the absence of a significant safety concern. |
2016-06-30 |
2023-08-13 |
Not clear |
| Theodor Baars, Ursula Neumann, Mona Jinawy, Stefanie Hendricks, Jan-Peter Sowa, Julia Kälsch, Mona Riemenschneider, Guido Gerken, Raimund Erbel, Dominik Heider, Ali Canba. In Acute Myocardial Infarction Liver Parameters Are Associated With Stenosis Diameter. Medicine. vol 95. issue 6. 2016-06-30. PMID:26871849. |
a prediction model (m10) was developed based on parameter importance analysis in rf.age, alkaline phosphatase (ap), aspartate aminotransferase (ast), and mld differed significantly between sd ≥ 50 and sd < 50. |
2016-06-30 |
2023-08-13 |
human |
| M Gholami, M Ravanshad, S-M Alavian, K Baesi, S Moallem. [Evaluation of miR-122 level in the plasma of chronically HCV infected patients]. Molekuliarnaia biologiia. vol 50. issue 2. 2016-06-30. PMID:27239848. |
the plasma levels of alanine transaminase (alt) and aspartate transaminase(ast) were correlated with plasma mir-122 level in chc patients, and the level of circulating mir-122 in healthy individual groups were rarely lower than those of patients with chc. |
2016-06-30 |
2023-08-13 |
Not clear |
| Chao Feng, Li-Juan Cao, Hua-Feng Song, Ping Xu, Hui Chen, Jun-Chi Xu, Xiao-Yan Zhu, Xue-Guang Zhang, Xue-Feng Wan. Expression of PD-L1 on CD4+CD25+Foxp3+ Regulatory T Cells of Patients with Chronic HBV Infection and Its Correlation with Clinical Parameters. Viral immunology. vol 28. issue 8. 2016-06-29. PMID:26266813. |
moreover, the results demonstrated that both treg frequency and pd-l1 expression on tregs positively correlated with the levels of alanine aminotransaminase (alt) and aspartate aminotransferase (ast), both of which are indicators of the extent of liver injury. |
2016-06-29 |
2023-08-13 |
Not clear |