| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| YiMin Zhang, JiMin Liu, Liang Yu, Ning Zhou, Wei Ding, ShuFa Zheng, Ding Shi, LanJuan L. Prevalence and characteristics of hypoxic hepatitis in the largest single-centre cohort of avian influenza A(H7N9) virus-infected patients with severe liver impairment in the intensive care unit. Emerging microbes & infections. vol 5. 2016-09-26. PMID:26733380. |
peak alanine aminotransferase (alt) and aspartate aminotransferase (ast) values were 937 and 1281 u/l, and 3117 and 3029 u/l, respectively, in the two patients. |
2016-09-26 |
2023-08-13 |
Not clear |
| Xi Chu, Hua Wang, Yan-min Jiang, Yuan-yuan Zhang, Yi-fan Bao, Xuan Zhang, Jian-ping Zhang, Hui Guo, Fan Yang, Yan-chao Luan, Yong-sheng Don. Ameliorative effects of tannic acid on carbon tetrachloride-induced liver fibrosis in vivo and in vitro. Journal of pharmacological sciences. vol 130. issue 1. 2016-09-26. PMID:26810570. |
pre-treatment of mice with ta (25 or 50 g/kg/day) significantly ameliorated hepatic morphology and coefficient values and reduced the activities of aspartate aminotransferase (ast) and alanine aminotransferase (alt), the concentrations of malondialdehyde (mda) and serum levels of endothelin-1 (et-1). |
2016-09-26 |
2023-08-13 |
mouse |
| Longfei Lin, Hongmei Lin, Miao Zhang, Boran Ni, Xingbin Yin, Changhai Qu, Jian N. A novel method to analyze hepatotoxic components in Polygonum multiflorum using ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry. Journal of hazardous materials. vol 299. 2016-09-23. PMID:26135484. |
toxicity was evaluated by using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), lactate dehydrogenase (ldh) leakage, and liver enzyme secretion (aspartate aminotransferase [ast] and alanine aminotransferase [alt]) assays. |
2016-09-23 |
2023-08-13 |
human |
| Emma L Anderson, Abigail Fraser, Laura D Howe, Mark P Callaway, Naveed Sattar, Chris Day, Kate Tilling, Debbie A Lawlo. Physical Activity Is Prospectively Associated With Adolescent Nonalcoholic Fatty Liver Disease. Journal of pediatric gastroenterology and nutrition. vol 62. issue 1. 2016-09-23. PMID:26252921. |
the aim of the present study was to assess whether objectively measured physical activity at mean ages 12 and 14 years are prospectively associated with ultrasound scan liver fat and stiffness (alanine aminotransferase, aspartate aminotransferase [ast], and γ-glutamyl transferase [ggt]) assessed at mean age 17.8 years. |
2016-09-23 |
2023-08-13 |
Not clear |
| Mustafa İçer, Yilmaz Zengin, Ercan Gunduz, Recep Dursun, Hasan Mansur Durgun, Gul Turkcu, Hatice Yuksel, Mehmet Üstündağ, Cahfer Gulogl. Is montelukast as effective as N-acetylcysteine in hepatic injury due to acetaminophen intoxication in rats? Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 68. issue 1. 2016-09-23. PMID:26462568. |
aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), and total bilirubin were studied from the blood samples. |
2016-09-23 |
2023-08-13 |
rat |
| Yuanyuan Hu, Yan Zhao, Daoyuan Ren, Jianjun Guo, Yiyang Luo, Xingbin Yan. Hypoglycemic and hepatoprotective effects of D-chiro-inositol-enriched tartary buckwheat extract in high fructose-fed mice. Food & function. vol 6. issue 12. 2016-09-22. PMID:26412138. |
continuous administration of dtbe in hf-fed mice dose-dependently reduced the hf-induced elevation of body weight, serum glucose, insulin, total cholesterol (tc), total triglycerides (tg) and low density lipoprotein cholesterol (ldl-c) levels, as well as serum alanine aminotransferase (alt), aspartate aminotransferase (ast), c-reactive protein (crp) and lactate dehydrogenase (ldh) activities, while the hf-induced decline of serum high density lipoprotein-cholesterol (hdl-c) levels could be markedly elevated in the mice. |
2016-09-22 |
2023-08-13 |
mouse |
| Wenxia Lu, Sainan Li, Jingjing Li, Jianrong Wang, Rong Zhang, Yuqing Zhou, Qin Yin, Yuanyuan Zheng, Fan Wang, Yujing Xia, Kan Chen, Tong Liu, Jie Lu, Yingqun Zhou, Chuanyong Gu. Effects of Omega-3 Fatty Acid in Nonalcoholic Fatty Liver Disease: A Meta-Analysis. Gastroenterology research and practice. vol 2016. 2016-09-21. PMID:27651787. |
a meta-analysis was conducted to assess the effect of omega-3 fatty acid supplementation (n-3 pufas) in lowering liver fat, liver enzyme (alanine aminotransferase (alt), aspartate aminotransferase (ast), and gamma-glutamyltransferase (ggt) levels), and blood lipids (triglyceride (tg), total cholesterol (tc), high density lipoprotein (hdl), and low density lipoprotein (ldl)) in patients with nonalcoholic fatty liver disease (nafld) or nonalcoholic steatohepatitis (nash). |
2016-09-21 |
2023-08-13 |
Not clear |
| Qiong Shi, Xiufang Song, Juanli Fu, Chuanyang Su, Xiaomin Xia, Erqun Song, Yang Son. Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice. International immunopharmacology. vol 29. issue 2. 2016-09-20. PMID:26362205. |
induced acute liver toxicity with the evidences of increased liver damage biomarkers, aspartate transaminase (ast) and alanine transaminase (alt) activities in serum. |
2016-09-20 |
2023-08-13 |
mouse |
| Nisha Bhatia, Prachi Gupta, Baljinder Singh, Ashwani Kou. Lycopene Enriched Tomato Extract Inhibits Hypoxia, Angiogenesis, and Metastatic Markers in early Stage N-Nitrosodiethylamine Induced Hepatocellular Carcinoma. Nutrition and cancer. vol 67. issue 8. 2016-09-20. PMID:26474105. |
the onset of hcc by ndea was associated with significant alteration in serum biochemical markers [alanine transaminases (alt), aspartate transaminases (ast), and alkaline phosphatases (alp), lactate dehydrogenase (ldh), urea, a/g ratio, and bilirubin] and in liver histopathology. |
2016-09-20 |
2023-08-13 |
mouse |
| Magdalena Stepien, Veronika Fedirko, Talita Duarte-Salles, Pietro Ferrari, Heinz Freisling, Elisabeth Trepo, Antonia Trichopoulou, Christina Bamia, Elisabete Weiderpass, Anja Olsen, Anne Tjønneland, Kim Overvad, Marie-Christine Boutron-Ruault, Guy Fagherazzi, Antoine Racine, Tilman Kühn, Rudolf Kaaks, Krasimira Aleksandrova, Heiner Boeing, Pagona Lagiou, Vassiliki Benetou, Dimitrios Trichopoulos, Domenico Palli, Sara Grioni, Rosario Tumino, Alessio Naccarati, Salvatore Panico, H Bas Bueno-de-Mesquita, Petra H Peeters, Eiliv Lund, J Ramón Quirós, Osmel Companioni Nápoles, María-José Sánchez, Miren Dorronsoro, José María Huerta, Eva Ardanaz, Bodil Ohlsson, Klas Sjöberg, Mårten Werner, Hanna Nystrom, Kay-Tee Khaw, Timothy J Key, Marc Gunter, Amanda Cross, Elio Riboli, Isabelle Romieu, Mazda Jena. Prospective association of liver function biomarkers with development of hepatobiliary cancers. Cancer epidemiology. vol 40. 2016-09-20. PMID:26773278. |
serum liver biomarkers (gamma-glutamyl transferase, ggt; alanine aminotransferase, alt; aspartate aminotransferase, ast; alkaline phosphatase, alp; total bilirubin) are used as indicators of liver disease, but there is currently little data on their prospective association with risk of hepatobiliary cancers. |
2016-09-20 |
2023-08-13 |
Not clear |
| Josely C Koury, Julio B Daleprane, Mario V Pitaluga-Filho, Cyntia F de Oliveira, Mariana C Gonçalves, Magna C F Passo. Aerobic Conditioning Might Protect Against Liver and Muscle Injury Caused by Short-Term Military Training. Journal of strength and conditioning research. vol 30. issue 2. 2016-09-15. PMID:26813633. |
creatine kinase (ck), aspartate aminotransferase (ast), and alanine aminotransferase (alt) serum levels were measured using an autoanalyzer. |
2016-09-15 |
2023-08-13 |
Not clear |
| Setor K Kunutsor, Stephan J L Bakker, Jenny E Kootstra-Ros, Hans Blokzijl, Ronald T Gansevoort, Robin P F Dullaar. Inverse linear associations between liver aminotransferases and incident cardiovascular disease risk: The PREVEND study. Atherosclerosis. vol 243. issue 1. 2016-09-14. PMID:26386210. |
alanine aminotransferase (alt) and aspartate aminotransferase (ast) have been linked with an increased risk of type 2 diabetes, but their relationships with cardiovascular disease (cvd) are uncertain. |
2016-09-14 |
2023-08-13 |
Not clear |
| Jinghua Wang, Chengfu Xu, Yunhao Xun, Zhenya Lu, Junping Shi, Chaohui Yu, Youming L. ZJU index: a novel model for predicting nonalcoholic fatty liver disease in a Chinese population. Scientific reports. vol 5. 2016-09-14. PMID:26568423. |
the model, named the zju index, was developed based on body mass index (bmi), fasting plasma glucose (fpg), triglycerides (tg), and the serum alanine aminotransferase (alt) to serum aspartate transaminase (ast) ratio. |
2016-09-14 |
2023-08-13 |
human |
| Heba M Hafez, Mohamed A Ibrahim, Salwa A Ibrahim, Entesar F Amin, Wafaey Goma, Aly M Abdelrahma. Potential protective effect of etanercept and aminoguanidine in methotrexate-induced hepatotoxicity and nephrotoxicity in rats. European journal of pharmacology. vol 768. 2016-09-13. PMID:26332135. |
mtx caused hepatotoxicity and nephrotoxicity as evidenced biochemically by significant increase in serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), urea and creatinine, respectively as well as by histopathological changes. |
2016-09-13 |
2023-08-13 |
rat |
| Linqiang Zhang, Zhiguo Zhang, Yunhai Li, Shasha Liao, Xiaoyun Wu, Qing Chang, Bin Lian. Cholesterol induces lipoprotein lipase expression in a tree shrew (Tupaia belangeri chinensis) model of non-alcoholic fatty liver disease. Scientific reports. vol 5. 2016-09-13. PMID:26522240. |
here, using high fat, cholesterol and cholate diet (hfhc), we generated a novel tree shrew (tupaia belangeri chinensis) model of nafld, which displayed dyslipidemia with increased levels of plasma alanine aminotransferase (alt) and aspartate aminotransferase (ast), total cholesterol (tc), low density lipoprotein-cholesterol (ldl-c) and high density lipoprotein-cholesterol (hdl-c), but decreased level of triglycerides (tg). |
2016-09-13 |
2023-08-13 |
Not clear |
| Qiang Li, Jie Song, Yuxian Huang, Xinyan Li, Qibin Zhuo, Weixia Li, Chong Chen, Chuan Lu, Xun Qi, Liang Che. The Gamma-Glutamyl-Transpeptidase to Platelet Ratio Does not Show Advantages than APRI and Fib-4 in Diagnosing Significant Fibrosis and Cirrhosis in Patients With Chronic Hepatitis B: A Retrospective Cohort Study in China. Medicine. vol 95. issue 16. 2016-09-13. PMID:27100421. |
the gamma-glutamyl-transpeptidase to platelet ratio (gpr) is a new liver fibrosis model, which is reported to be more accurate than aspartate transaminase (ast) to platelet ratio index (apri) and fibrosis index based on the four factors (fib-4) for diagnosing significant fibrosis and cirrhosis in patients with chronic hepatitis b (chb) in west africa. |
2016-09-13 |
2023-08-13 |
Not clear |
| Takehito Suzuki, Hideo Fukuoka, Setsuo Ushikoshi, Reiichiro Sato, Hidetoshi Morita, Tatsuya Takizaw. Protective effect of aqueous extracts from Rhizopus oryzae on liver injury induced by carbon tetrachloride in rats. Animal science journal = Nihon chikusan Gakkaiho. vol 86. issue 5. 2016-09-12. PMID:25496319. |
(i) pretreatment with ru caused a significant decrease in serum lactate dehydrogenase (ldh), alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities that were increased by the administration of ccl4 . |
2016-09-12 |
2023-08-13 |
rat |
| G Christodoulopoulos, A Kassab, G Theodoropoulo. Characteristics of non-cerebral coenurosis in tropical goats. Veterinary parasitology. vol 211. issue 3-4. 2016-09-12. PMID:26073108. |
the only abnormalities observed in the infected goats were palpation of large single cysts in thigh muscles and higher serum aspartate aminotransferase (ast) value. |
2016-09-12 |
2023-08-13 |
Not clear |
| Mahmoud Elshal, Nashwa Abu-Elsaad, Amr El-Karef, Tarek Mostafa Ibrahi. The multi-kinase inhibitor pazopanib targets hepatic stellate cell activation and apoptosis alleviating progression of liver fibrosis. Naunyn-Schmiedeberg's archives of pharmacology. vol 388. issue 12. 2016-09-12. PMID:26269412. |
levels of liver function biomarkers (alanine aminotransferase (alt), aspartate aminotransferase (ast), albumin, and total bilirubin), malondialdehyde, transforming growth factor-β1 (tgf-β1), caspase-3, factor-related apoptosis (fas), vascular endothelial growth factor (vegf) receptor-1, and pigment endothelial derived factor (pedf) were measured. |
2016-09-12 |
2023-08-13 |
Not clear |
| Chuanpeng Zhou, Heizhao Lin, Zhong Huang, Jun Wang, Yun Wang, Wei Y. Effects of dietary soybean isoflavones on non-specific immune responses and hepatic antioxidant abilities and mRNA expression of two heat shock proteins (HSPs) in juvenile golden pompano Trachinotus ovatus under pH stress. Fish & shellfish immunology. vol 47. issue 2. 2016-09-12. PMID:26518502. |
after 56 days of feeding, 15 fish per tank were exposed to ph stress (ph ≈ 9.2) for 24 h. serum total protein (tp), respiratory burst activity (rba), alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (akp), lysozyme (lyz), complement 3 (c3), complement 4 (c4), cortisol, hepatic total antioxidant capacity (t-aoc), superoxide dismutase (sod), malondialdehyde (mda), catalase (cat) and the relative mrna expression of heat shock protein 70 (hsp70) and 90 (hsp90) were investigated. |
2016-09-12 |
2023-08-13 |
cat |