| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yang Liu, Dandan Zheng, Ling Su, Qi Wang, Yu L. Protective effect of polysaccharide from Agaricus bisporus in Tibet area of China against tetrachloride-induced acute liver injury in mice. International journal of biological macromolecules. vol 118. issue Pt B. 2018-11-21. PMID:29969638. |
the results from hepatoprotective studies showed that fps significantly decreased the liver index, serum gamma-glutamyltranspeptidase (ggt), alanine aminotransferase (alt), alkaline phosphatase (alp), aspartate aminotransferase (ast) activities and malondialdehyde (mda) contents in liver tissue, and increased antioxidant capacities of hepatic glutathione (gsh) and superoxide dismutase (sod). |
2018-11-21 |
2023-08-13 |
mouse |
| Yiming Zhou, Beibei Yan, Shen Zhao, Xiaoli Zhou, Ying Xia. Toxicological analysis of roast duck flavor components. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 119. 2018-11-19. PMID:29208505. |
compared with the control group, the blood biochemical indexes including protein content, bilirubin content, activity of alkaline phosphatase, activity of aspartate transaminase (ast) and alanine transaminase (alt), cholesterol content, high density lipoprotein (hdl) and low density lipoprotein (ldl) content, triglycerides content, activity of creatine kinase (ck) and ck-mb, activity of cholinesterase (che) and lactate dehydrogenase (ldh), total bile acid (tba) in high dose feeding group were significantly different. |
2018-11-19 |
2023-08-13 |
mouse |
| Wei Liu, Zi Wang, Jin-Gang Hou, Yan-Dan Zhou, Yu-Fang He, Shuang Jiang, Ying-Ping Wang, Shen Ren, Wei L. The Liver Protection Effects of Maltol, a Flavoring Agent, on Carbon Tetrachloride-Induced Acute Liver Injury in Mice via Inhibiting Apoptosis and Inflammatory Response. Molecules (Basel, Switzerland). vol 23. issue 9. 2018-11-19. PMID:30142916. |
the results clearly indicated that the intrapulmonary injection of ccl₄ resulted in a sharp increase in serum aspartate transaminase (ast) and alanine transaminase (alt) activities, tumor necrosis factor-α (tnf-α), irreducible nitric oxide synthase (inos), nuclear factor-kappa b (nf-κb) and interleukin-1β (il-1β) levels. |
2018-11-19 |
2023-08-13 |
mouse |
| Maha H Sharawy, Noha Abdel-Rahman, Nirmeen Megahed, Mohammed S El-Awad. Paclitaxel alleviates liver fibrosis induced by bile duct ligation in rats: Role of TGF-β1, IL-10 and c-Myc. Life sciences. vol 211. 2018-11-15. PMID:30243650. |
administration of ptx ameliorated bdl-induced elevation in biomarkers of hepatocellular damage (alanine transaminase; alt and aspartate transaminase; ast) and obstructive cholestatic injury (total bilirubin and gamma glutamyl transferase; γ-gt). |
2018-11-15 |
2023-08-13 |
rat |
| Jisong Chen, Haiwei Liu, Xianlin Zhan. [Protective effects of rosiglitazone on hepatic ischemia reperfusion injury in rats]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 43. issue 7. 2018-11-14. PMID:30124208. |
two hours after reperfusion, serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities, lactate dehydrogenase (ldh) level, malondialdehyde (mda) content and catalase (cat), glutathione peroxidase (gpx) and superoxide dismutase (sod) activities were examined. |
2018-11-14 |
2023-08-13 |
rat |
| Zhihong Ma, Li Chu, Hongying Liu, Weijie Wang, Jieru Li, Wenzao Yao, Jianfeng Yi, Yue Ga. Beneficial effects of paeoniflorin on non-alcoholic fatty liver disease induced by high-fat diet in rats. Scientific reports. vol 7. 2018-11-12. PMID:28300221. |
our results demonstrated that hfd resulted in hepatocellular ballooning, micro-/macrovesicular steatosis, and oxidative stress in the liver, accompanied by increased serum total cholesterol (tc), triglyceride (tg), free fatty acid (ffa), alanine aminotransferase (alt), and aspartate aminotransferase (ast) levels and homeostasis model of insulin resistance (homa-ir) index. |
2018-11-12 |
2023-08-13 |
rat |
| Maria Edvardsson, Märtha Sund-Levander, Anna Milberg, Ewa Wressle, Jan Marcusson, Ewa Grodzinsk. Differences in levels of albumin, ALT, AST, γ-GT and creatinine in frail, moderately healthy and healthy elderly individuals. Clinical chemistry and laboratory medicine. vol 56. issue 3. 2018-11-12. PMID:28988219. |
the aim of the study was to assess levels of albumin, alanine aminotransferase (alt), aspartate aminotransferase (ast), creatinine and γ-glutamyl transferase (γ-gt) in frail, moderately healthy and healthy elderly indivuduals. |
2018-11-12 |
2023-08-13 |
Not clear |
| Jessica Nardi, Sabrina Nascimento, Gabriela Göethel, Bruna Gauer, Elisa Sauer, Nuryan Fão, Larissa Cestonaro, Caroline Peruzzi, Jorge Souza, Solange Cristina Garci. Inflammatory and oxidative stress parameters as potential early biomarkers for silicosis. Clinica chimica acta; international journal of clinical chemistry. vol 484. 2018-11-12. PMID:29860036. |
vitamin c levels were decreased, while c3, hscrp, ada, and aspartate aminotransferase (ast) levels were increased in the iws group compared to the ouw group (p < 0.05). |
2018-11-12 |
2023-08-13 |
human |
| Zhong-Feng Wang, Mao-Yu Wang, De-Hai Yu, Yan Zhao, Hong-Mei Xu, Sheng Zhong, Wen-Yi Sun, Yu-Fang He, Jun-Qi Niu, Pu-Jun Gao, Hai-Jun L. Therapeutic effect of chitosan on CCl4‑induced hepatic fibrosis in rats. Molecular medicine reports. vol 18. issue 3. 2018-11-12. PMID:30085342. |
the serum levels of aspartate transaminase (ast), alanine transaminase (alt) and alkaline phosphatase (alp) were measured by elisa. |
2018-11-12 |
2023-08-13 |
rat |
| Canhong Wang, Xiaowei Huo, Li Gao, Guibo Sun, Cao L. Hepatoprotective Effect of Carboxymethyl Pachyman in Fluorouracil-Treated CT26-Bearing Mice. Molecules (Basel, Switzerland). vol 22. issue 5. 2018-11-09. PMID:28481246. |
our results showed that cmp administration increased the tumor inhibitory rates of 5-fu and, meanwhile, it reversed reduction of peripheral white blood cells (wbc) and bone marrow nucleated cells (bmnc), increase of alanine aminotransferase (alt) and aspartate aminotransferase (ast), and decrease of superoxide dismutase (sod), catalase (cat), gsh-px and glutathione(gsh) induced by 5-fu. |
2018-11-09 |
2023-08-13 |
mouse |
| Rong Fan, Peng-Chao Hu, Ying Wang, Hong-Yi Lin, Ke Su, Xue-Song Feng, Lei Wei, Fang Yan. Betulinic acid protects mice from cadmium chloride-induced toxicity by inhibiting cadmium-induced apoptosis in kidney and liver. Toxicology letters. vol 299. 2018-11-09. PMID:30232032. |
the levels of serum alanine aminotransferase (alt), aspartate aminotransferase (ast) and blood urea nitrogen (bun) were assessed by elisa. |
2018-11-09 |
2023-08-13 |
mouse |
| Ahmed M Fayez, Soad Zakaria, Dina Moustaf. Alpha lipoic acid exerts antioxidant effect via Nrf2/HO-1 pathway activation and suppresses hepatic stellate cells activation induced by methotrexate in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 105. 2018-11-06. PMID:29879626. |
blood samples and liver tissues were then obtained to assess several biochemical parameters as serum alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), reduced glutathione (gsh), total antioxidant capacity (tac) and lipid peroxidation. |
2018-11-06 |
2023-08-13 |
rat |
| Mohsen Taghizadeh, Ali Akbar Rashidi, Ali Akbar Taherian, Zarichehr Vakili, Mehdi Mehra. The Protective Effect of Hydroalcoholic Extract of Rosa canina (Dog Rose) Fruit on Liver Function and Structure in Streptozotocin-Induced Diabetes in Rats. Journal of dietary supplements. vol 15. issue 5. 2018-11-05. PMID:29095652. |
this study was conducted to evaluate the hepatoprotective effects of rosa canina (r. canina) extract on streptozotocin- (stz-) induced diabetes in rats by measuring the fasting blood glucose (fbg), total antioxidant capacity (tac), and liver enzyme activity, including serum alanine aminotransferase (alt) and aspartate aminotransferase (ast). |
2018-11-05 |
2023-08-13 |
rat |
| Belma Haliloğlu, Heybet Tüzün, Sarah E. Flanagan, Muhittin Çelik, Avni Kaya, Sian Ellard, Mehmet Nuri Özbe. Sirolimus-Induced Hepatitis in Two Patients with Hyperinsulinemic Hypoglycemia Journal of clinical research in pediatric endocrinology. vol 10. issue 3. 2018-11-05. PMID:29217498. |
at follow-up after ten and two months of treatment, liver enzymes were found to be increased [serum sirolimus level 1.4 ng/ml (normal range: 5-15), aspartate aminotransferase (ast): 298u/l, alanine aminotransferase (alt): 302u/l and serum sirolimus level: 9.9 ng/ml, ast: 261u/l, alt: 275u/l, respectively]. |
2018-11-05 |
2023-08-13 |
Not clear |
| Mikaela P Pinz, Angélica S Dos Reis, Ane G Vogt, Roberta Krüger, Diego Alves, Cristiano R Jesse, Silvane S Roman, Mauro P Soares, Ethel A Wilhelm, Cristiane Luches. Current advances of pharmacological properties of 7-chloro-4-(phenylselanyl) quinoline: Prevention of cognitive deficit and anxiety in Alzheimer's disease model. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 105. 2018-11-02. PMID:30021335. |
on the fifteenth day, blood was removed for analysis of biochemical markers (glucose, triglycerides, urea, aspartate (ast) and alanine (alt) aminotrasferases), and cerebral cortex and hippocampus for determination of ache activity and thiobarbituric acid reactive species (tbars) levels. |
2018-11-02 |
2023-08-13 |
mouse |
| Yan Liu, Hong Wang, Chen Dong, Jie-Xiong Feng, Zhi-Hua Huan. Clinical Features and Genetic Analysis of Pediatric Patients with Alagille Syndrome Presenting Initially with Liver Function Abnormalities. Current medical science. vol 38. issue 2. 2018-11-02. PMID:30074189. |
serum total cholesterol (tc) (p=0.0007), alanine aminotransferase (alt) (p=0.0056), aspartate aminotransferase (ast) (p=0.0114), gamma-glutamyl transferase (ggt) (p=0.035) and total bile acid (tba) levels (p=0.042) were significantly elevated in ags patients compared to those in ba cases. |
2018-11-02 |
2023-08-13 |
Not clear |
| Hisakuni Obayashi, Naoko Kobayashi, Yoshikazu Nezu, Takashi Yamoto, Mitsuyuki Shirai, Fumitoshi Asa. Plasma 2-hydroxyglutarate, a promising prognostic biomarker candidate for skeletal muscle injury in Fischer 344 rats. The Journal of toxicological sciences. vol 43. issue 10. 2018-11-02. PMID:30298848. |
here, we examined whether plasma 2hg was superior to conventional skeletal muscle damage biomarkers, including aspartate aminotransferase (ast), creatine kinase (ck), and skeletal muscle-type ck isoenzyme (ck-mm) levels, in rats. |
2018-11-02 |
2023-08-13 |
rat |
| Yu P Orlov, N V Govorova, A V Glushchenko, E N Efremov, Yu B Vasilenk. [A critical incident during marathon competition as a result of metabolic decompensation]. Klinicheskaia meditsina. vol 95. issue 1. 2018-11-01. PMID:30299072. |
this medication reduced ast and alt activities and utilization of endogenous enzymes for succinate synthesis from alanine and aspartate under hypoxic conditions. |
2018-11-01 |
2023-08-13 |
human |
| Samira Azadbakht, Mohammad Ali Norouzian, Ali Akbar Khade. Assessing the protective effect of bentonite against lead toxicity in growing lambs. Environmental science and pollution research international. vol 24. issue 35. 2018-10-31. PMID:28980189. |
lead intake resulted in a decrease (p < 0.05) in serum fe and an increase in serum pb, aspartate aminotransferase (ast), and alanine aminotransferase (alt) activities (p < 0.05). |
2018-10-31 |
2023-08-13 |
Not clear |
| Maurya Khushboo, Meesala Krishna Murthy, Maibam Sunita Devi, Sanasam Sanjeev, Kalibulla Syed Ibrahim, Nachimuthu Senthil Kumar, Vikas Kumar Roy, Guruswami Gurusubramania. Testicular toxicity and sperm quality following copper exposure in Wistar albino rats: ameliorative potentials of L-carnitine. Environmental science and pollution research international. vol 25. issue 2. 2018-10-31. PMID:29103113. |
the parameters included were sperm quality (concentration, viability, motility, and morphology), histopathology, serum aspartate aminotransferase (ast), serum alanine aminotransferase (alt), serum urea, serum creatinine, serum testosterone and testis antioxidant enzyme levels (superoxide dismutase and glutathione-s-transferase), and biomarkers of oxidative stress (lipid peroxidation and expression of heat shock protein 70 in testis). |
2018-10-31 |
2023-08-13 |
rat |