| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Asmaa A Hassan, Noura M Thabet, Mohamed Kh Abdel-Rafe. Hyaluronan as a mediator for the hepatoprotective effect of Diosmin/Hesperidin complex. Pakistan journal of pharmaceutical sciences. vol 31. issue 4. 2019-08-19. PMID:30033401. |
our results showed the ameliorative effect of daflon on cytochrome p450 (cyt p450), lipid peroxidation (mda), liver enzymes (aspartate amino transferase; ast, alanine aminotransferase; alt and gamma glutamyl transferase; γ-gt), antioxidant capacity (reduced glutathione; gsh and glutathione per oxidase; gpx), inflammatory markers (c-reactive protein; crp and interlukin- 6; il-6), alpha-fetoprotein (afp) and extra cellular matrix proteins (hyaluronan; ha and hyaluronidase; haase) which was supported by histopathological examination of liver sections compared to the damage induced in ccl4 and/or rats exposed to radiation. |
2019-08-19 |
2023-08-13 |
rat |
| Aline Boveto Santamarina, Giovana Jamar, Laís Vales Mennitti, Daniel Araki Ribeiro, Caroline Margonato Cardoso, Veridiana Vera de Rosso, Lila Missae Oyama, Luciana Pellegrini Pisan. Polyphenols-Rich Fruit ( Molecules (Basel, Switzerland). vol 24. issue 9. 2019-08-19. PMID:31035535. |
the hfj0.25% group had the energy intake, aspartate transaminase (ast) levels, and liver triacylglycerol accumulation reduced; also, the tumor necrosis factor α (tnf-α) and tnf receptor-associated factor 6 (traf6) expression in ret were reduced. |
2019-08-19 |
2023-08-13 |
rat |
| Kosisochi Chinwendu Amorha, Onyinyechukwu Blessing Ugwuowo, Ebere Emilia Ayogu, Sunday Odunke Nduka, Mathew Jegbefume Okont. Evaluation of the hepatic effect of concomitant administration of ciprofloxacin and some antimalarial drugs in Plasmodium berghei infected mice: An in vivo study. Pakistan journal of pharmaceutical sciences. vol 31. issue 5. 2019-08-16. PMID:30150174. |
statistical analysis revealed that cip alone significantly (p<0.05) reduced the levels of aspartate transaminase (ast) and serum alanine transaminase (alt) compared to as, al and asaq alone. |
2019-08-16 |
2023-08-13 |
mouse |
| Fahad Said Khan, Muhammad Akram, Nosheen Aslam, Jawad Zaheer, Sodah Bint Mustafa, Shamaila Kausar, Abdul Hamid Khan, Iftikhar Ahmad Khan, Naveed Munir, Syed Muhammad Ali Shah, Imtiaz Mahmood Tahir, Aamir Shari. Phytochemical analysis and hepatoprotective effect of polyherbal formulation on CCl4 induced hepatotoxicity in mice. Pakistan journal of pharmaceutical sciences. vol 31. issue 6 (Supplementary. 2019-08-16. PMID:30587485. |
ccl4intoxicationinduced vacuole formation and fastdegeneration so selective liver enzymes including alanine aminotransferase (alt) and aspartate aminotransferase (ast), alkalinephosphatase (alp) and total bilirubin in rat's plasma,as well as liver histological architecture, were used to evaluate the effect of herbal treatments with different doses (ranging 100-500 mg/kg) for two weeks. |
2019-08-16 |
2023-08-13 |
mouse |
| Emna El Golli-Bennour, Rim Timoumi, Emna Annaibi, Moncef Mokni, Asma Omezzine, Hassen Bacha, Salwa Abid-Essef. Protective effects of kefir against deltamethrin-induced hepatotoxicity in rats. Environmental science and pollution research international. vol 26. issue 18. 2019-08-15. PMID:31062243. |
kefir administration normalized the elevated serum levels of aspartate aminotransferase (ast), alanine aminotransferase (alt), total bilirubin (t bilirubin), and cholesterol. |
2019-08-15 |
2023-08-13 |
human |
| Benjamim de Souza Nahúm, Naiara Zoccal Saraiva, Cristian Faturi, André Guimarães Maciel E Silva, José de Brito Lourenço, José Silva de Sousa, João Maria do Amaral, Guilherme de Paula Nogueira, Gisele Zoccal Mingot. Effect of dietary supplementation of palm kernel cake on ovarian and hepatic function in buffalo (Bubalus bubalis). Animal reproduction science. vol 204. 2019-08-14. PMID:30935774. |
amount of pkc supplementation did not affect the concentrations of alanine aminotransferase, but there was a greater amount of aspartate aminotransferase (ast) and gamma glutamyl transferase (ggt) during both phases of the estrous cycle (p < 0.05). |
2019-08-14 |
2023-08-13 |
Not clear |
| Doaa Mohammed Youssef, Hanaa Abdo, Ahmed Alakhras, Tamer Adham, Abdelnasser Hussien Mohamou. Hepatitis C in children with chronic kidney disease: A single-center, Egypt. Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia. vol 28. issue 1. 2019-08-13. PMID:28098110. |
all patients underwent a thorough history taking including disease duration and mean duration of admission, clinical examination including blood pressure measurements, and routine laboratory examination such as hemoglobin level, serum aspartate aminotransferase (ast), alanine aminotransferase (alt), urea, and creatinine. |
2019-08-13 |
2023-08-13 |
Not clear |
| S Topsakal, O Ozmen, M Ozgocme. Effects of alpha-lipoic acid on high fructose induced hepatic pathology. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 94. issue 4. 2019-08-13. PMID:30632398. |
a significant increase was observed in the serum aspartate aminotransferase (ast) level of the hfcs group compared to controls. |
2019-08-13 |
2023-08-13 |
rat |
| S Meydan, M Esrefoglu, S Selek, E Akbas Tosunoglu, O Ozturk, N Kurbetli, N Bayındır, H Bulut, I Mera. Protective effects of caffeic acid phenethyl ester and thymoquinone on toluene induced liver toxicity. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 94. issue 4. 2019-08-13. PMID:30821514. |
serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels were measured to evaluate liver function. |
2019-08-13 |
2023-08-13 |
rat |
| Gersina Rega-Kaun, Dorothea Ritzel, Christoph Kaun, Benjamin Ebenbauer, Barbara Thaler, Manfred Prager, Svitlana Demyanets, Johann Wojta, Philipp J Hohensinne. Changes of Circulating Extracellular Vesicles from the Liver after Roux-en-Y Bariatric Surgery. International journal of molecular sciences. vol 20. issue 9. 2019-08-13. PMID:31052333. |
surgery led to a massive reduction of weight and overall hepatic stress as determined by alanine transaminase (alt), aspartate transaminase (ast) and γ-glutamyltransferase (ggt). |
2019-08-13 |
2023-08-13 |
Not clear |
| Biao Jiang, Geling Lu, Jiajia Du, Jing Wang, Yazhou Hu, Youlu Su, Anxing L. First report of trypanosomiasis in farmed largemouth bass (Micropterus salmoides) from China: pathological evaluation and taxonomic status. Parasitology research. vol 118. issue 6. 2019-08-12. PMID:31049695. |
the serum of diseased fish had significantly lower concentrations of glucose, triglyceride, and low-density lipoprotein, and significantly higher alanine transaminase (alt), aspartate transaminase (ast), and lactate dehydrogenase (ldh) activities. |
2019-08-12 |
2023-08-13 |
Not clear |
| D Barski, A Spodniewsk. Effect of chlorpyrifos and enrofloxacin on selected enzymes in rats. Polish journal of veterinary sciences. vol 21. issue 1. 2019-08-09. PMID:29624020. |
this study examined the effect of chlorpyrifos and/or enrofloxacin on the activity of acetylcholinesterase (ache) in the blood and brain, and the activity of alanine aminotransferase (alt) and aspartate aminotransferase (ast) in serum. |
2019-08-09 |
2023-08-13 |
rat |
| Liwen Zhang, Shulan Su, Yue Zhu, Jianming Guo, Sheng Guo, Dawei Qian, Zhen Ouyang, Jin-Ao Dua. Mulberry leaf active components alleviate type 2 diabetes and its liver and kidney injury in db/db mice through insulin receptor and TGF-β/Smads signaling pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 112. 2019-08-08. PMID:30780108. |
while the mf and ma possessed a significant effect on liver damage, manifested in reducing the levels of alt (alanine aminotransferase) and ast (aspartate aminotransferase) and pathological changes of liver on db/db mice. |
2019-08-08 |
2023-08-13 |
mouse |
| Hongli Guo, Jieyu Sun, Deyi Li, Yahui Hu, Xiaowen Yu, Hu Hua, Xia Jing, Feng Chen, Zhanjun Jia, Jing X. Shikonin attenuates acetaminophen-induced acute liver injury via inhibition of oxidative stress and inflammation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 112. 2019-08-08. PMID:30818140. |
the results revealed that shikonin pretreatment prevented the elevation of serum alanine transaminase (alt), aspartate transaminase (ast) and lactate dehydrogenase (ldh) levels and markedly reduced apap-induced histological alterations in liver tissues. |
2019-08-08 |
2023-08-13 |
mouse |
| Mustafa Cengiz, Songul Cetik Yildiz, Cemil Demir, İlknur Kulcanay Şahin, Özgün Teksoy, Adnan Ayhanc. Hepato-preventive and anti-apoptotic role of boric acid against liver injury induced by cyclophosphamide. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). vol 53. 2019-08-08. PMID:30910191. |
the present study was carried out using routine histological h&e stain, immunohistochemical stain caspase-3 as apoptotic marker, serum biochemical analysis for liver function markers (alanine transaminase (alt), aspartate transaminase (ast) and alkalen phosphatase (alp)), oxidative stress markers (total oxidant status (tos), oxidative stress index (osi) and total antioxidant capacity marker (tac)). |
2019-08-08 |
2023-08-13 |
rat |
| Congjian Shi, Weiju Xue, Bowen Han, Fengli Yang, Yaping Yin, Chengmu H. Acetaminophen aggravates fat accumulation in NAFLD by inhibiting autophagy via the AMPK/mTOR pathway. European journal of pharmacology. vol 850. 2019-08-06. PMID:30753863. |
apap treatment significantly aggravated hepatic lipid accumulation, increased the serum levels of triglyceride (tg), alanine aminotransferase (alt) and aspartate aminotransferase (ast), and increased hepatic lipid accumulation in h&e and oil red o staining results. |
2019-08-06 |
2023-08-13 |
mouse |
| Jamal Rahmani, Ali Miri, Iman Namjoo, Negar Zamaninour, Mohammad B Maljaei, Kehua Zhou, Raminta Cerneviciute, Seyed M Mousavi, Hamed K Varkaneh, Ammar Salehisahlabadi, Yong Zhan. Elevated liver enzymes and cardiovascular mortality: a systematic review and dose-response meta-analysis of more than one million participants. European journal of gastroenterology & hepatology. vol 31. issue 5. 2019-08-05. PMID:30614883. |
gamma glutamyl transferase (ggt), alanine aminotransferase (alt), aspartate aminotransferase (ast), and alkaline phosphatase (alp) are commonly used liver function markers. |
2019-08-05 |
2023-08-13 |
human |
| E Fazio, A Ferlazzo, S Cristarella, P Medica, G Marino, M Quartucci. The stress response of Ragusano donkey (Equus asinus) to different semen collection techniques. Polish journal of veterinary sciences. vol 20. issue 4. 2019-08-02. PMID:29611652. |
the aim of the present study was to characterize the stress response of donkeys to different semen collection techniques, comparing the physiological patterns of hormonal (adrenocorticotropic hormone: acth, cortisol) and biochemical variables (creatinine, total protein, urea, aspartate aminotransferase: ast, alanine aminotransferase: alt), and routine seminal parameters and sexual behaviour. |
2019-08-02 |
2023-08-13 |
human |
| Sandra Franco, Daniela Buccione, Raquel Pluvinet, Beatriz Mothe, Lidia Ruiz, Maria Nevot, Ana Jordan-Paiz, Laia Ramos, Susanna Aussó, Rosa M Morillas, Lauro Sumoy, Miguel Angel Martinez, Cristina Tura. Large-scale screening of circulating microRNAs in individuals with HIV-1 mono-infections reveals specific liver damage signatures. Antiviral research. vol 155. 2019-08-01. PMID:29807039. |
importantly, most of these mirnas significantly and positively correlated with alt and aspartate aminotransferase (ast) levels, and liver fibrosis stage (p < 0.05). |
2019-08-01 |
2023-08-13 |
human |
| J Lee, M Y Kim, S H Kang, J Kim, Y Uh, K J Yoon, H S Ki. The gamma-glutamyl transferase to platelet ratio and the FIB-4 score are noninvasive markers to determine the severity of liver fibrosis in chronic hepatitis B infection. British journal of biomedical science. vol 75. issue 3. 2019-07-31. PMID:29893189. |
fibroscan assessments were made, and blood taken for the measurement of the gamma-glutamyl transferase (ggt) to platelet ratio (gpr), platelet count, aspartate aminotransaminase (ast), alanine aminotransaminase (alt), international normalised ratio (inr), total cholesterol, trigylcerides, bilirubin, mean platelet volume (mpv), ast to platelet ratio index (apri) and neutrophil to lymphocyte ratio. |
2019-07-31 |
2023-08-13 |
Not clear |