| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qian Li, Lin Bai, Guiying Shi, Lianfeng Zhang, Yifan Dai, Pingsheng Liu, Yu-Sheng Cong, Miao Wan. Ptrf transgenic mice exhibit obesity and fatty liver. Clinical and experimental pharmacology & physiology. vol 45. issue 7. 2019-09-16. PMID:29381831. |
compared with wild-type (wt) mice, we found that the ptrf transgenic mice showed obesity with an increased level of alt (alanine aminotransferase) and ast (aspartate transaminase). |
2019-09-16 |
2023-08-13 |
mouse |
| Jie Yu, Jing Yang, Mizhuan Li, Xuesong Yang, Pan Wang, Jie X. Protective effects of Chinese Fenggang zinc selenium tea on metabolic syndrome in high-sucrose-high-fat diet-induced obese rats. Scientific reports. vol 8. issue 1. 2019-09-16. PMID:29476111. |
significant decreases in serum alanine aminotransferase (alt), aspartate aminotransferase (ast), total bile acids (tba), alkaline phosphatase (alp), and direct bilirubin (dbil) levels were observed in zthl-group versus the ch-group (p < 0.05). |
2019-09-16 |
2023-08-13 |
rat |
| Kyung Mook Choi, Kyungdo Han, Sanghyun Park, Hye Soo Chung, Nam Hoon Kim, Hye Jin Yoo, Ji-A Seo, Sin Gon Kim, Nan Hee Kim, Sei Hyun Baik, Yong Gyu Park, Seon Mee Ki. Implication of liver enzymes on incident cardiovascular diseases and mortality: A nationwide population-based cohort study. Scientific reports. vol 8. issue 1. 2019-09-16. PMID:29491346. |
although liver enzymes, such as γ-glutamyltransferase (ggt), alanine aminotransferase (alt), and aspartate aminotransferase (ast), have recently been suggested as risk factors for cardiovascular diseases (cvd), impact on mortality after myocardial infarction (mi) or ischemic stroke (is) was not previously examined. |
2019-09-16 |
2023-08-13 |
Not clear |
| Laura Adamovicz, John Griffioen, Anthony Cerreta, Gregory A Lewbart, Matthew C Allende. TISSUE ENZYME ACTIVITIES IN FREE-LIVING EASTERN BOX TURTLES ( Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. vol 50. issue 1. 2019-09-16. PMID:31120661. |
this study evaluated tissue specificity of six biochemical enzymes (alanine aminotransferase [alt], aspartate aminotransferase [ast], alkaline phosphatase [alp], creatine kinase [ck], gamma-glutamyl transferase [ggt], and glutamate dehydrogenase [gldh]) in 10 tissues (skeletal muscle, cardiac muscle, lung, liver, gallbladder, pancreas, gastrointestinal tract, kidney, spleen, and reproductive tract) from 10 free-living eastern box turtles ( |
2019-09-16 |
2023-08-13 |
Not clear |
| Xin-Yi Liu, Zhong-Biao Jiang, Jie Luo, Jian-He Li, Xiong-Bin H. [In vitro evaluation, cellular uptake and anti-acute myocardial ischemia effect of puerarin PEG-PLGA micelles]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 44. issue 11. 2019-09-16. PMID:31359649. |
the st segment changes in the electrocardiogram were monitored; serum creatine kinase(ck), lactate dehydrogenase(ldh), aspartate aminotransferase(ast), and malondialdehyde(mda) levels were detected and myocardial infarct size was also measured. |
2019-09-16 |
2023-08-13 |
rat |
| H Asci, O Ozmen, Y Erzurumlu, A Sofu, P Icten, M Kayna. Agomelatine protects heart and aorta against lipopolysaccharide-induced cardiovascular toxicity via inhibition of NF-kβ phosphorylation. Drug and chemical toxicology. 2019-09-13. PMID:31514555. |
total oxidant status (tos), total antioxidant status (tas), nuclear factor kappa beta (nf-kβ)/p65, p-nf-kβ, full caspase-8 (cas-8) and cleaved cas-8 levels were measured in cardiac tissues and creatine kinase mb (ckmb), aspartate aminotransferase (ast), lactate dehydrogenase (ldh) levels in blood biochemically. |
2019-09-13 |
2023-08-13 |
rat |
| Li-Shan Zhou, Su-Qi Yan, Xiao-Li Xiong, Juan Huang, Huan Qin, Ling-Ling Zhang, Lin-Li Zhang, Jian-Qiao Tan. [Psoralen and isopsoralen improve lipid metabolism disorder via inhibition of NF-κB activation in LO2 cells]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 44. issue 10. 2019-09-12. PMID:31355570. |
intracellular triglyceride( tg) and total cholesterol( tc) content,the cell supernatant alanine aminotransferase( alt) and aspartate aminotransferase( ast) levels were determined by enzyme method. |
2019-09-12 |
2023-08-13 |
human |
| Cigdem Velioglu, Mehmet E Erdemli, Mehmet Gul, Zeynep Erdemli, Emrah Zayman, Harika G Bag, Eyup Altino. Protective effect of crocin on food azo dye tartrazine-induced hepatic damage by improving biochemical parameters and oxidative stress biomarkers in rats. General physiology and biophysics. vol 38. issue 1. 2019-09-10. PMID:30657462. |
furthermore, tartrazine administration resulted in significant increases in plasma aspartate aminotransferase (ast), alanine aminotransferase (alt) and alkaline phosphatase (alp) activities and pathological changes in the liver. |
2019-09-10 |
2023-08-13 |
rat |
| Sanasam Sanjeev, Rema Momin Bidanchi, Meesala Krishna Murthy, Guruswami Gurusubramanian, Vikas Kumar Ro. Influence of ferulic acid consumption in ameliorating the cadmium-induced liver and renal oxidative damage in rats. Environmental science and pollution research international. vol 26. issue 20. 2019-09-10. PMID:31104231. |
liver and kidney damage induced by cd was significantly revealed by the reduction in serum total protein contents (tpc) and increased activities of serum nitric oxide (no) levels and hepato-nephrotoxicity marker enzymes, namely aspartate transaminase (ast), alanine transaminase (alt), alkaline phosphatase (alp), lactic dehydrogenase (ldh), ast:alt ratio, uric acid, urea, urea nitrogen, and creatinine, along with the increased levels of hepatic and renal oxidative stress markers, namely lipid peroxidation (mda levels), lipid hydroperoxides (looh), protein carbonyl content (pcc), total oxidant status (tos), and oxidative stress index (osi) in liver and kidney tissues. |
2019-09-10 |
2023-08-13 |
rat |
| Said M Afify, Ashraf Tabll, Hend M Nawara, Mohamed El Kassas, Ashraf Elfert, Masaharu Seno, Salah El-Kous. Five Fibrosis Biomarkers Together with Serum Ferritin Level to Diagnose Liver Fibrosis and Cirrhosis. Clinical laboratory. vol 64. issue 10. 2019-09-09. PMID:30336529. |
in this study, we tried to use serum ferritin (sf) together with five fibrosis tests (age-platelet index (api), aspartate aminotransferase to alanine aminotransferase ratio (aar), ast to platelet ratio index (apri), fibrosis 4 score (fib-4), and fibro-quotient (fibro-q)) to assess liver fibrosis and cirrhosis and estimate possible correlation between inflammation and sf. |
2019-09-09 |
2023-08-13 |
Not clear |
| Li Zhou, Shao-Bin Wang, Shu-Guang Chen, Qiang Qu, Jing-An Ru. Prognostic Value of ALT, AST, and AAR in Hepatocellular Carcinoma with B-Type Hepatitis-Associated Cirrhosis after Radical Hepatectomy. Clinical laboratory. vol 64. issue 10. 2019-09-09. PMID:30336532. |
alanine aminotransferase (alt), aspartate aminotransferase (ast), and ast to alt ratio (aar) were shown to be associated with prognosis in some groups of hepatocellular carcinoma (hcc). |
2019-09-09 |
2023-08-13 |
Not clear |
| Lorna Stemberger Maric, Neven Papic, Mario Sestan, Ivica Knezovic, Goran Tesovi. Challenges in early diagnosis of Kawasaki disease in the pediatric emergency department: differentiation from adenoviral and invasive pneumococcal disease. Wiener klinische Wochenschrift. vol 130. issue 7-8. 2019-09-06. PMID:29476365. |
the levels of platelets (plt), aspartate aminotransferase (ast) and alanine aminotransferase (alt) were higher and white blood cells (wbc) significantly lower in kd than in ipd and adv group. |
2019-09-06 |
2023-08-13 |
Not clear |
| J Wang, J Xia, R Zhang, X Yan, Y Yang, X Zhao, H Chang, G Wang, G Chen, Y Liu, Y Chen, B Jia, Z Zhang, W Ding, R Huang, C W. A novel index using routine clinical parameters for predicting significant liver inflammation in chronic hepatitis B. Journal of viral hepatitis. vol 25. issue 10. 2019-09-06. PMID:29741221. |
the diagnostic performance of gpr for significant inflammation was significantly superior to that of alanine aminotransferase (alt), aspartate transaminase (ast) and ggt in all patients with chb and hbeag-positive chb patients, but was comparable with alt, ast and ggt in hbeag-negative chb patients. |
2019-09-06 |
2023-08-13 |
Not clear |
| Mehrez E El-Naggar, Fakhria Al-Joufi, Mona Anwar, Mohamed F Attia, Mona A El-Ban. Curcumin-loaded PLA-PEG copolymer nanoparticles for treatment of liver inflammation in streptozotocin-induced diabetic rats. Colloids and surfaces. B, Biointerfaces. vol 177. 2019-09-05. PMID:30785036. |
next, complete blood analyses were assessed including alanine aminotransferase (alt), aspartate aminotransferase (ast), and nuclear factor kappa b (nf-ҡb), reduced glutathione (gsh), malondialdehyde (mda), nitric oxide (no), cyclooxygenase (cox-2), peroxisome proliferator-activated receptors (ppar-γ) and transforming growth factor-β1 (tgf-β1). |
2019-09-05 |
2023-08-13 |
rat |
| Xu Cong Ruan, Lian Leng Low, Yu Heng Kwa. Association of aspartate aminotransferase in statin-induced rhabdomyolysis. Journal of primary health care. vol 9. issue 4. 2019-09-03. PMID:29530144. |
results aspartate aminotransferase (ast) was found to be positively associated with peak ck levels in the multivariable linear regression model after adjusting for alanine aminotransferase (alt) levels (p = 0.002; β = 83.18). |
2019-09-03 |
2023-08-13 |
Not clear |
| Xue-Yuan Jin, Chuan-Bao Zhu, Shi-Yong Fan, Jia-Lin Sun, Yu-Cong Shi, Chu-Han Wang, Hui-Fen Wang, Bo-Hua Zhong, Yi-Shan Yao, Wei-Guo Sh. Novel hypolipidemic conjugates of fatty acid and bile acid with lysine for linkage. Drug development and industrial pharmacy. vol 45. issue 6. 2019-09-02. PMID:30892088. |
conjugates of stearic acid with cholic acid and palmitic acid with ursodeoxycholic acid (at dosages of 50, 100, and 200 mg/kg) were further evaluated to determine their ability to reduce aspartate aminotransferase (ast), alanine aminotransferase (alt), tc, and tg levels in mice fed with hfd. |
2019-09-02 |
2023-08-13 |
mouse |
| Yaohong Liu, Wensou Huang, Mingji He, Hui Lian, Yongjian Guo, Jingjun Huang, Jingwen Zhou, Kangshun Zh. Efficacy and Safety of CalliSpheres Oncology research. vol 27. issue 5. 2019-08-27. PMID:30005719. |
the number of patients with abnormal aspartate aminotransferase (ast) did not increase at 1 week but elevated at 1 month. |
2019-08-27 |
2023-08-13 |
Not clear |
| Ji Su Kim, Ji Yeon Son, Kyeong Seok Kim, Hyun Jung Lim, Mee-Young Ahn, Seung Jun Kwack, Young-Mi Kim, Kwang Youl Lee, Jaewon Lee, Byung Mu Lee, Hyung Sik Ki. Hepatic damage exacerbates cisplatin-induced acute kidney injury in Sprague-Dawley rats. Journal of toxicology and environmental health. Part A. vol 81. issue 11. 2019-08-22. PMID:29557720. |
no significant changes in serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) activity were observed after cddp treatment. |
2019-08-22 |
2023-08-13 |
rat |
| Jintian He, Yu Niu, Fei Wang, Chao Wang, Tao Cui, Kaiwen Bai, Jingfei Zhang, Xiang Zhong, Lili Zhang, Tian Wan. Dietary curcumin supplementation attenuates inflammation, hepatic injury and oxidative damage in a rat model of intra-uterine growth retardation. The British journal of nutrition. vol 120. issue 5. 2019-08-21. PMID:30043720. |
rats with iugr showed higher (p<0·05) concentrations of tnf-α, il-1β and il-6; higher (p<0·05) activities of aspartate aminotransferase (ast) and alanine aminotransferase (alt) in their serum; and increased (p<0·05) concentrations of malondialdehyde (mda), protein carbonyl (pc) and 8-hydroxy-2'-deoxyguanosine (8-ohdg) in the liver compared with the nbw rats. |
2019-08-21 |
2023-08-13 |
rat |
| Yu Zhang, Qiang Shen, Yuanxing Liu, Hui Chen, Xiaoxiao Zheng, Shangzhi Xie, Haofeng Ji, Shusen Zhen. Hepatic Ischemic Preconditioning Alleviates Ischemia-Reperfusion Injury by Decreasing TIM4 Expression. International journal of biological sciences. vol 14. issue 10. 2019-08-20. PMID:30123068. |
liver function was evaluated using the level of alanine transaminase (alt) and aspartate transaminase (ast), cell apoptosis and pathological examination. |
2019-08-20 |
2023-08-13 |
mouse |