| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| O T Phillipson, P C Emson, A S Horn, T Jessel. Evidence concerning the anatomical location of the dopamine stimulated adenylate cyclase in the substantia nigra. Brain research. vol 136. issue 1. 1978-02-18. PMID:22389. |
evidence concerning the anatomical location of the dopamine stimulated adenylate cyclase in the substantia nigra. |
1978-02-18 |
2023-08-11 |
rat |
| O T Phillipson, P C Emson, A S Horn, T Jessel. Evidence concerning the anatomical location of the dopamine stimulated adenylate cyclase in the substantia nigra. Brain research. vol 136. issue 1. 1978-02-18. PMID:22389. |
the dopamine (da)-sensitive adenylate cyclase in the substantia nigra was assayed in rats which had been subjected to 3 different kinds of brain lesion: (1) unilateral 6-hydroxydopamine (6-ohda) lesions of the medial forebrain bundle; (2) unilateral lesions of the descending strio-nigral and pallido-nigral projections; (3) total lesions of the serotoninergic raphe-nigral pathway. |
1978-02-18 |
2023-08-11 |
rat |
| M Schlumpf, W J Shoemaker, F E Bloo. Explant cultures of catecholamine-containing neurons from rat brain: biochemical, histofluorescence, and electron microscopic studies. Proceedings of the National Academy of Sciences of the United States of America. vol 74. issue 10. 1978-01-27. PMID:270693. |
norepinephrine (ne)-producing cells of the nucleus locus ceruleus and dopamine (da)-producing cells of the substantia nigra were dissected microscopically from embryonic rat brain, explanted, and maintained in culture for up to 5 weeks. |
1978-01-27 |
2023-08-11 |
rat |
| A S Heritage, L D Grant, W E Stump. 3H estradiol in catecholamine neurons of rat brain stem: combined localization by autoradiography and formaldehyde-induced fluorescence. The Journal of comparative neurology. vol 176. issue 4. 1978-01-27. PMID:562904. |
in the midbrain, dopamine (da)-containing neurons in the n. cuneiformis (group a8), in the zona compacta of the substantia nigra (group a9) and adjacent to the n. interpeduncularis (group a10), were not seen to concentrate 3h estradiol. |
1978-01-27 |
2023-08-11 |
rat |
| K G Lloy. CNS compensation to dopamine neuron loss in Parkinson's disease. Advances in experimental medicine and biology. vol 90. 1978-01-27. PMID:930746. |
postmortem examination of parkinson's disease brains and study of animal models indicate that the following mechanisms may contribute to this cns compensation: 1) a decrease in striatal cholinergic activity, in an attempt to maintain a critical da:ach balance; and 2) a decrease in activity of gaba neurons in the striatum and substantia nigra, resulting in an increased firing rate of nigral dopamine cells. |
1978-01-27 |
2023-08-11 |
Not clear |
| A Chéramy, A Nieoullon, J Glowinsk. Stimulating effects of gamma-hydroxybutyrate on dopamine release from the caudate nucleus and the substantia nigra of the cat. The Journal of pharmacology and experimental therapeutics. vol 203. issue 2. 1977-11-30. PMID:909063. |
stimulating effects of gamma-hydroxybutyrate on dopamine release from the caudate nucleus and the substantia nigra of the cat. |
1977-11-30 |
2023-08-11 |
cat |
| A Nieoullon, A Cheramy, J Glowinsk. Interdependence of the nigrostriatal dopaminergic systems on the two sides of the brain in the cat. Science (New York, N.Y.). vol 198. issue 4315. 1977-11-30. PMID:910137. |
a lesion made in the left substantia nigra interrupted the release of [3h]dopamine in the ipsilateral caudate nucleus and was associated with a simultaneous increase in the release of [3h]dopamine on the contralateral side. |
1977-11-30 |
2023-08-11 |
cat |
| A Nieoullon, A Cheramy, J Glowinsk. Interdependence of the nigrostriatal dopaminergic systems on the two sides of the brain in the cat. Science (New York, N.Y.). vol 198. issue 4315. 1977-11-30. PMID:910137. |
the release of [3h]dopamine also decreased in the left caudate nucleus and increased in the right structure when dopamine was applied to the left substantia nigra which reduces the activity of the left dopaminergic pathway. |
1977-11-30 |
2023-08-11 |
cat |
| J C Reubi, L L Iversen, T M Jessel. Dopamine selectively increases 3H-GABA release from slices of rat substantia nigra in vitro. Nature. vol 268. issue 5621. 1977-10-31. PMID:197423. |
dopamine selectively increases 3h-gaba release from slices of rat substantia nigra in vitro. |
1977-10-31 |
2023-08-11 |
rat |
| G Racagni, F Bruno, F Cattabeni, A Maggi, A M Di Giulio, M Parenti, A Groppett. Functional interaction between rat substantia nigra and striatum: GABA and dopamine interrelation. Brain research. vol 134. issue 2. 1977-10-31. PMID:890495. |
functional interaction between rat substantia nigra and striatum: gaba and dopamine interrelation. |
1977-10-31 |
2023-08-11 |
rat |
| J Bockaert, J Premont, J Glowinski, J P Tassin, A M Thierr. Topographical distribution and characteristics of dopamine and beta-adrenergic sensitive adenylate cyclases in the rat frontal cerebral cortex, striatum, and substantia nigra. Advances in biochemical psychopharmacology. vol 16. 1977-09-17. PMID:196489. |
topographical distribution and characteristics of dopamine and beta-adrenergic sensitive adenylate cyclases in the rat frontal cerebral cortex, striatum, and substantia nigra. |
1977-09-17 |
2023-08-11 |
rat |
| P M Grove. Possible mechanisms involved in the stereotyped behavior elicited by amphetamine. Biological psychiatry. vol 12. issue 3. 1977-08-12. PMID:194632. |
current evidence, for example, suggests that amphetamine produces an inhibition of neuronal activity in the neostriatum and pars compacta of the substantia nigra by means of dopamine released from dopaminergic terminals in the neostriatum and dopaminergic dendrites in the substantia nigra respectively. |
1977-08-12 |
2023-08-11 |
rat |
| G K Aghajanian, B S Bunne. Dopamine"autoreceptors": pharmacological characterization by microiontophoretic single cell recording studies. Naunyn-Schmiedeberg's archives of pharmacology. vol 297. issue 1. 1977-06-30. PMID:193046. |
the effects on the firing of single dopamine (da) neurons in the substantia nigra (and adjacent ventral tegmental area) of a representative group of catecholamine agonists and antagonists were studied in rats using single cell recording and microiontophoretic techniques. |
1977-06-30 |
2023-08-11 |
rat |
| A Nieoullon, A Cheramy, J Glowinsk. Release of dopamine in vivo from cat substantia nigra. Nature. vol 266. issue 5600. 1977-06-30. PMID:859606. |
release of dopamine in vivo from cat substantia nigra. |
1977-06-30 |
2023-08-11 |
cat |
| U Seeber, K Kuschinsk. Effects of penfluridol of dopamine-sensitive adenylate cyclase in corpus striatum and substantia nigra of rats. Experientia. vol 32. issue 12. 1977-05-12. PMID:191279. |
penfluridol, a neuroleptic with diphenylbutyl piperidine structure, blocked the dopamine-sensitive adenylate cyclase in homogenates of corpus striatum and substantia nigra of rats, probably by a competitive antagonism versus dopamine. |
1977-05-12 |
2023-08-11 |
rat |
| K Gale, A Guidotti, E Cost. Dopamine-sensitive adenylate cyclase: location in substantia nigra. Science (New York, N.Y.). vol 195. issue 4277. 1977-03-31. PMID:13499. |
in contrast, brain hemitransection between the striatum and substantia nigra, or a more circumscribed lesion of striatonigral pathways, abolished the dopamine stimulation of adenylate cyclase in the substantia nigra. |
1977-03-31 |
2023-08-11 |
rat |
| K Gale, A Guidotti, E Cost. Dopamine-sensitive adenylate cyclase: location in substantia nigra. Science (New York, N.Y.). vol 195. issue 4277. 1977-03-31. PMID:13499. |
these results suggest that dopamine receptors within the substantia nigra are not located on dopamine cell bodies but are associated with a pathway, containing gamma-aminobutyric acid or substance p, which projects from forebrain structures to the substantia nigra. |
1977-03-31 |
2023-08-11 |
rat |
| C J Pycock, C D Marsde. Central deopaminergic receptor supersensitivity and its relevance to Parkinson's disease. Journal of the neurological sciences. vol 31. issue 1. 1977-03-31. PMID:833607. |
the degeneration of the substantia nigra that characterises parkinson's disease may cause an alteration in sensitivity of striatal dopamine receptors. |
1977-03-31 |
2023-08-11 |
mouse |
| A Dray, T J Gonye, N R Oakle. Effects of alpha-flupenthixol on dopamine and 5-hydroxytryptamine responses of substantia nigra neurones. Neuropharmacology. vol 15. issue 12. 1977-03-31. PMID:1012444. |
effects of alpha-flupenthixol on dopamine and 5-hydroxytryptamine responses of substantia nigra neurones. |
1977-03-31 |
2023-08-11 |
Not clear |
| J Korf, M Zieleman, B H Westerin. Metabolism of dopamine in the substantia nigra after antidromic activation. Brain research. vol 120. issue 1. 1977-03-15. PMID:832118. |
metabolism of dopamine in the substantia nigra after antidromic activation. |
1977-03-15 |
2023-08-11 |
Not clear |