| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Klarica, D Fage, C Carte. Pharmacology of N-methyl-D-aspartate-evoked [3H]noradrenaline release in adult rat spinal cord. European journal of pharmacology. vol 308. issue 2. 1997-01-15. PMID:8840124. |
in comparison with previously characterised nmda responses in the striatum, (release of dopamine, gaba, acetylcholine or spermidine) the spinal response was particularly sensitive to mk-801 and magnesium and to l-689,560 but not to other glycine receptor antagonists (7-chlorokynurenate, cnqx (6-cyano-7-nitroquinoxaline-2,3-dione), dnqx (6,7-dichloroquinoxaline-2,3-dione), (+)-ha966). |
1997-01-15 |
2023-08-12 |
rat |
| M Kurokawa, K Koga, H Kase, J Nakamura, Y Kuwan. Adenosine A2a receptor-mediated modulation of striatal acetylcholine release in vivo. Journal of neurochemistry. vol 66. issue 5. 1997-01-14. PMID:8780014. |
the cgs 21680-induced elevation of acetylcholine release was still observed in the presence of gaba antagonists bicuculline (30 microm) and 2-hydroxysaclofen (100 microm) and was similar in both normal and dopamine-depleted striatum. |
1997-01-14 |
2023-08-12 |
rat |
| I M Stanford, M G Lace. Differential actions of serotonin, mediated by 5-HT1B and 5-HT2C receptors, on GABA-mediated synaptic input to rat substantia nigra pars reticulata neurons in vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 23. 1997-01-06. PMID:8922413. |
one, probably originating from the striatum, may be depressed via presynaptic 5-ht1b and gaba(b) receptors. |
1997-01-06 |
2023-08-12 |
rat |
| M S Desole, G Esposito, L Fresu, R Migheli, P Enrico, M A Mura, G De Natale, E Miele, M Miel. Effects of morphine treatment and withdrawal on striatal and limbic monoaminergic activity and ascorbic acid oxidation in the rat. Brain research. vol 723. issue 1-2. 1996-12-03. PMID:8813393. |
since ascorbic acid (aa) reportedly suppresses tolerance to and dependence on morphine in humans and rodents, levels of dopamine (da), dihydroxyphenylacetic acid (dopac), homovanillic acid (hva), 3-methoxytyramine (3-mt), 5-hydroxytryptamine (5-ht), 5-hydroxyindoleacetic acid (5-hiaa), aa, dehydroascorbic acid (dhaa), uric acid, xanthine, hypoxanthine, glutamate and gamma-aminobutyric acid (gaba) were determined by high-pressure liquid chromatography (hplc) in the striatum and in the limbic forebrain of the rat following morphine treatment (single or repeated) and withdrawal. |
1996-12-03 |
2023-08-12 |
rat |
| C K Meshul, J F Buckman, C Allen, J P Riggan, D J Felle. Activation of corticostriatal pathway leads to similar morphological changes observed following haloperidol treatment. Synapse (New York, N.Y.). vol 22. issue 4. 1996-12-03. PMID:8867029. |
the increase in asymmetric synapses with perforated psds and in glutamate immunoreactivity within nerve terminals of the striatum following either subchronic haloperidol treatment or gaba injections into vl/vm suggest that an increase in glutamate release may be a common factor in these two experiments. |
1996-12-03 |
2023-08-12 |
Not clear |
| M Morari, W T O'Connor, M Darvelid, U Ungerstedt, C Bianchi, K Fux. Functional neuroanatomy of the nigrostriatal and striatonigral pathways as studied with dual probe microdialysis in the awake rat--I. Effects of perfusion with tetrodotoxin and low-calcium medium. Neuroscience. vol 72. issue 1. 1996-10-24. PMID:8730707. |
perfusion with a low-ca2+ (0.1 mm) medium and with the voltage-dependent na(+)-channel blocker tetrodotoxin (10 microm) was alternatively performed in both brain regions and the dialysate dopamine, glutamate and gaba levels were simultaneously measured in the dorsolateral striatum, whereas gaba levels alone were monitored in the substantia nigra. |
1996-10-24 |
2023-08-12 |
rat |
| M Morari, W T O'Connor, M Darvelid, U Ungerstedt, C Bianchi, K Fux. Functional neuroanatomy of the nigrostriatal and striatonigral pathways as studied with dual probe microdialysis in the awake rat--I. Effects of perfusion with tetrodotoxin and low-calcium medium. Neuroscience. vol 72. issue 1. 1996-10-24. PMID:8730707. |
perfusion with a low-ca2+ medium in the dorsolateral striatum reversibly decreased local dopamine (-70%), glutamate (-20%) and gaba (-20%) levels, while local perfusion with tetrodotoxin decreased dopamine (-70%), increased glutamate (+30%) but did not affect dialysate gaba levels in this brain area. |
1996-10-24 |
2023-08-12 |
rat |
| M Morari, W T O'Connor, U Ungerstedt, C Bianchi, K Fux. Functional neuroanatomy of the nigrostriatal and striatonigral pathways as studied with dual probe microdialysis in the awake rat--II. Evidence for striatal N-methyl-D-aspartate receptor regulation of striatonigral GABAergic transmission and motor function. Neuroscience. vol 72. issue 1. 1996-10-24. PMID:8730708. |
perfusion with n-methyl-d-aspartate (100 microm) in the dorsolateral striatum decreased local dopamine release (-25%) and increased both glutamate (+40%) and gaba (+35%) release. |
1996-10-24 |
2023-08-12 |
rat |
| M Morari, W T O'Connor, U Ungerstedt, C Bianchi, K Fux. Functional neuroanatomy of the nigrostriatal and striatonigral pathways as studied with dual probe microdialysis in the awake rat--II. Evidence for striatal N-methyl-D-aspartate receptor regulation of striatonigral GABAergic transmission and motor function. Neuroscience. vol 72. issue 1. 1996-10-24. PMID:8730708. |
moreover, perfusion with n-methyl-d-aspartate (100 microm) in the dorsolateral striatum increased gaba release (+20%) in the substantia nigra pars reticulata. |
1996-10-24 |
2023-08-12 |
rat |
| M Morari, W T O'Connor, U Ungerstedt, C Bianchi, K Fux. Functional neuroanatomy of the nigrostriatal and striatonigral pathways as studied with dual probe microdialysis in the awake rat--II. Evidence for striatal N-methyl-D-aspartate receptor regulation of striatonigral GABAergic transmission and motor function. Neuroscience. vol 72. issue 1. 1996-10-24. PMID:8730708. |
perfusion with the lower (10 microm) n-methyl-d-aspartate concentration in the dorsolateral striatum did not affect striatal dopamine, glutamate and gaba release or nigral gaba release. |
1996-10-24 |
2023-08-12 |
rat |
| M Morari, W T O'Connor, U Ungerstedt, C Bianchi, K Fux. Functional neuroanatomy of the nigrostriatal and striatonigral pathways as studied with dual probe microdialysis in the awake rat--II. Evidence for striatal N-methyl-D-aspartate receptor regulation of striatonigral GABAergic transmission and motor function. Neuroscience. vol 72. issue 1. 1996-10-24. PMID:8730708. |
the present study demonstrates that n-methyl-d-aspartate receptors in the dorsolateral striatum regulate gaba release in the substantia nigra pars reticulata of the awake rat and provides evidence that this regulation plays a key role in motor function. |
1996-10-24 |
2023-08-12 |
rat |
| B G Xue, J M Friend, K W Ge. Loreclezole modulates [35S]t-butylbicyclophosphorothionate and [3H]flunitrazepam binding via a distinct site on the GABAA receptor complex. European journal of pharmacology. vol 300. issue 1-2. 1996-10-17. PMID:8741177. |
loreclezole modulation of [35s]tbps binding showed greater potency and gaba sensitivity in the cerebellum and thalamus when compared to other brain regions such as the cortex, hippocampus and striatum. |
1996-10-17 |
2023-08-12 |
rat |
| J Peri. Repeated cocaine injections decrease the function of striatal gamma-aminobutyric acid(A) receptors. The Journal of pharmacology and experimental therapeutics. vol 276. issue 3. 1996-09-20. PMID:8786528. |
the function of gaba(a) receptors to transport chloride was assessed in striatum and other brain regions of male rats that had received daily injections of cocaine (15 mg/kg i.p.) |
1996-09-20 |
2023-08-12 |
rat |
| J Peri. Repeated cocaine injections decrease the function of striatal gamma-aminobutyric acid(A) receptors. The Journal of pharmacology and experimental therapeutics. vol 276. issue 3. 1996-09-20. PMID:8786528. |
thus, gaba(a) receptor function in striatum may be selectively decreased by cocaine treatment which may contribute to changes in behavioral sensitization caused by cocaine. |
1996-09-20 |
2023-08-12 |
rat |
| S A Thornberg, S R Sakla. A review of NMDA receptors and the phencyclidine model of schizophrenia. Pharmacotherapy. vol 16. issue 1. 1996-09-04. PMID:8700797. |
by decreasing glutamatergic neurotransmission, phencyclidine decreases gamma-aminobutyric acid release from the nucleus accumbens, striatum, and hippocampus (manifested by mk-801); may inhibit tonic release of dopamine from the nucleus accumbens and striatum, resulting in increased dopamine phasic reactivity; and decreases long-term potentiation. |
1996-09-04 |
2023-08-12 |
Not clear |
| M A Chapman, R E Se. Differential effects of unique profile antipsychotic drugs on extracellular amino acids in the ventral pallidum and globus pallidus of rats. The Journal of pharmacology and experimental therapeutics. vol 277. issue 3. 1996-08-06. PMID:8667227. |
the effects of antipsychotic drugs (apds) on brain dopamine receptors in the striatum are ultimately expressed through efferent projections which primarily use amino acid transmitters, including gamma-aminobutyric acid and glutamate. |
1996-08-06 |
2023-08-12 |
rat |
| K Andreasson, P F Worle. Induction of beta-A activin expression by synaptic activity and during neocortical development. Neuroscience. vol 69. issue 3. 1996-04-18. PMID:8596648. |
expression of beta-a activin messenger rna is rapidly regulated in early postnatal cortex and striatum by gaba and glutamate antagonists, suggesting that beta-a activin is also regulated as a rapid response gene in developing brain, and that the high basal levels reflect a steady-state response to developmental signals. |
1996-04-18 |
2023-08-12 |
rat |
| T Mainprize, A Shuaib, S Ijaz, R Kanthan, H Miyashita, J Kalr. GABA concentrations in the striatum following repetitive cerebral ischemia. Neurochemical research. vol 20. issue 8. 1996-03-25. PMID:8587654. |
gaba concentrations in the striatum following repetitive cerebral ischemia. |
1996-03-25 |
2023-08-12 |
Not clear |
| A Rakovsk. Cholecystokinin-GABA interactions in rat striatum. Neuropeptides. vol 29. issue 5. 1996-03-25. PMID:8587661. |
the activation of cck-b receptors located on gabaergic neurons is involved in the gaba release-potentiating effect of cck-8s in rat striatum. |
1996-03-25 |
2023-08-12 |
rat |
| A Porras, F Mor. Dopamine--glutamate--GABA interactions and ageing: studies in the striatum of the conscious rat. The European journal of neuroscience. vol 7. issue 11. 1996-03-04. PMID:8563968. |
dopamine--glutamate--gaba interactions and ageing: studies in the striatum of the conscious rat. |
1996-03-04 |
2023-08-12 |
rat |