| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Takahiro Nakazawa, Takaaki Yasuda, Joji Ueda, Keisuke Ohsaw. Antidepressant-like effects of apigenin and 2,4,5-trimethoxycinnamic acid from Perilla frutescens in the forced swimming test. Biological & pharmaceutical bulletin. vol 26. issue 4. 2003-11-21. PMID:12673028. |
forced swimming exposure induced a significant decrease in dihydroxyphenylacetic acid (dopac)/dopamine (da) in the striatum and amygdala and in 5-hydroxyindoleacetic acid (5-hiaa)/5-hydroxytriptamine (5-ht) in the hypothalamus, and a significant increase in dopac/da in the thalamus and hypothalamus and in 3-methoxy-4-hydroxyphenylethyleneglycol (mhpg)/norepinephrine (ne) in the amygdala, frontal cortex, hypothalamus, and midbrain. |
2003-11-21 |
2023-08-12 |
mouse |
| Acioly L T Lacerda, Paulo Dalgalarrondo, Dorgival Caetano, Edwaldo E Camargo, Elba C S C Etchebehere, Jair C Soare. Elevated thalamic and prefrontal regional cerebral blood flow in obsessive-compulsive disorder: a SPECT study. Psychiatry research. vol 123. issue 2. 2003-11-04. PMID:12850251. |
functional neuroimaging studies have pointed to a possible role of cerebral circuits involving the prefrontal and anterior cingulate cortices, the striatum, and thalamus in the pathophysiology of obsessive-compulsive disorder (ocd). |
2003-11-04 |
2023-08-12 |
human |
| M Modo, K Hopkins, D Virley, H Hodge. Transplantation of neural stem cells modulates apolipoprotein E expression in a rat model of stroke. Experimental neurology. vol 183. issue 2. 2003-10-31. PMID:14552873. |
apoe immunoreactivity was highly expressed in the striatum, somatosensory cortex, and thalamus of the lesioned hemisphere in all rats subjected to middle cerebral artery occlusion. |
2003-10-31 |
2023-08-12 |
rat |
| Christian Andriamampandry, Omar Taleb, Sandrine Viry, Claude Muller, Jean Paul Humbert, Serge Gobaille, Dominique Aunis, Michel Maitr. Cloning and characterization of a rat brain receptor that binds the endogenous neuromodulator gamma-hydroxybutyrate (GHB). FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 17. issue 12. 2003-10-08. PMID:12958178. |
its mrna is restricted to the brain and is particularly abundant in the hippocampus, cortex, striatum, thalamus, olfactory bulbs, and cerebellum, matching the distribution of ghb binding sites in rat brain. |
2003-10-08 |
2023-08-12 |
human |
| Jennifer E Learn, Daniel G Smith, William J McBride, Lawrence Lumeng, Ting-Kai L. Ethanol effects on local cerebral glucose utilization in high-alcohol-drinking and low-alcohol-drinking rats. Alcohol (Fayetteville, N.Y.). vol 29. issue 1. 2003-09-24. PMID:12657371. |
after administration of both low (0.25 g/kg) and moderate (1.0 g/kg) doses of ethanol, lcgu values were lower, relative to those for saline controls, in several cns regions (lateral septum; posterior cingulate, frontal, parietal, and temporal cortices; dorsomedial striatum; and dorsomedial thalamus) of lad but not had rats. |
2003-09-24 |
2023-08-12 |
rat |
| Jaspreet Kaur, Sangeeta Singh, Deepak Sharma, Rameshwar Sing. Neurostimulatory and antioxidative effects of L-deprenyl in aged rat brain regions. Biogerontology. vol 4. issue 2. 2003-09-12. PMID:12766535. |
this study investigated the influence of chronically administered l-deprenyl on normal ageing-related parameters: multiple unit action potentials, the activities of the enzymes na(+),k(+)-adenosine triphosphatase, glutathione-s-transferase and glutathione peroxidase, and the levels of lipid peroxidation products and lipofuscin contents in the brain regions (cerebral cortex, hippocampus, striatum and thalamus) of 24-month-old rats. |
2003-09-12 |
2023-08-12 |
rat |
| H Umemori, H Ogura, N Tozawa, K Mikoshiba, H Nishizumi, T Yamamot. Impairment of N-methyl-D-aspartate receptor-controlled motor activity in LYN-deficient mice. Neuroscience. vol 118. issue 3. 2003-08-08. PMID:12710978. |
a src family kinase lyn is highly expressed in striatum, cortex, thalamus, and cerebellum in the brain. |
2003-08-08 |
2023-08-12 |
mouse |
| Katsumasa T Muneoka, Morikuni Takigaw. 5-Hydroxytryptamine7 (5-HT7) receptor immunoreactivity-positive 'stigmoid body'-like structure in developing rat brains. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 21. issue 3. 2003-07-01. PMID:12711351. |
in adult male rats, 5-ht(7) receptor immunoreactivity was detected in the septum, striatum, indusium griseum, tenia tecta, thalamus, hippocampus and hypothalamus in the forebrain as well as the pons and cerebellum. |
2003-07-01 |
2023-08-12 |
rat |
| Yiyun Huang, Dah-Ren Hwang, Zhihong Zhu, Sung-A Bae, Ningning Guo, Yasuhiko Sudo, Lawrence S Kegeles, Marc Laruell. Synthesis and pharmacological characterization of a new PET ligand for the serotonin transporter: [11C]5-bromo-2-[2-(dimethylaminomethylphenylsulfanyl)]phenylamine ([11C]DAPA). Nuclear medicine and biology. vol 29. issue 7. 2003-05-19. PMID:12381454. |
biodistribution studies in rats indicated that [11c]dapa enters into the brain readily and localizes in brain regions known to contain high concentrations of sert, such as the thalamus, hypothalamus, frontal cortex and striatum. |
2003-05-19 |
2023-08-12 |
rat |
| Yiyun Huang, Dah-Ren Hwang, Zhihong Zhu, Sung-A Bae, Ningning Guo, Yasuhiko Sudo, Lawrence S Kegeles, Marc Laruell. Synthesis and pharmacological characterization of a new PET ligand for the serotonin transporter: [11C]5-bromo-2-[2-(dimethylaminomethylphenylsulfanyl)]phenylamine ([11C]DAPA). Nuclear medicine and biology. vol 29. issue 7. 2003-05-19. PMID:12381454. |
imaging experiments in baboons indicated that [11c]dapa binding is consistent with the known distribution of sert in the baboon brain, with highest levels of radioactivity detected in the midbrain and thalamus, intermediate levels in the hippocampus and striatum, and lower levels in the cortical regions. |
2003-05-19 |
2023-08-12 |
rat |
| Akihiro Takano, Tetsuya Suhara, Yasuhiko Sudo, Makoto Inoue, Kenji Hashimoto, Ming-Rong Zhang, Tetsuya Ichimiya, Fumihiko Yasuno, Kazutoshi Suzuk. Comparative evaluation of two serotonin transporter ligands in the human brain: [(11)C](+)McN5652 and [(11)C]cyanoimipramine. European journal of nuclear medicine and molecular imaging. vol 29. issue 10. 2003-05-07. PMID:12271409. |
in the brain, high accumulation was observed in the thalamus and striatum, the regions known to contain high densities of 5-ht transporter, for both [(11)c](+)mcn5652 and [(11)c]cyanoimipramine. |
2003-05-07 |
2023-08-12 |
human |
| Rodrigo A Bressan, Kjell Erlandsson, Hugh M Jones, Rachel S Mulligan, Peter J Ell, Lyn S Pilowsk. Optimizing limbic selective D2/D3 receptor occupancy by risperidone: a [123I]-epidepride SPET study. Journal of clinical psychopharmacology. vol 23. issue 1. 2003-05-07. PMID:12544369. |
six patients treated with low-dose risperidone (mean = 2.6 mg) showed moderate levels of d2/d3 occupancy in striatum (49.9%), but higher levels of d2/d3 occupancy in thalamus (70.8%) and temporal cortex (75.2%). |
2003-05-07 |
2023-08-12 |
human |
| Y POURSINES, J BOUDOURESQUES, J ROGE. [Diffuse atrophic degenerative process, predominantly of the thalamus and corpus striatum; variable extrapyramidal and psychic semeiology; subacute evolution with terminal dementia]. Revue neurologique. vol 89. issue 4. 2003-05-01. PMID:13167895. |
[diffuse atrophic degenerative process, predominantly of the thalamus and corpus striatum; variable extrapyramidal and psychic semeiology; subacute evolution with terminal dementia]. |
2003-05-01 |
2023-08-12 |
Not clear |
| M B CARPENTE. Status marmoratus of the thalamus and striatum associated with athetosis and dystonia. Neurology. vol 5. issue 2. 2003-05-01. PMID:13235989. |
status marmoratus of the thalamus and striatum associated with athetosis and dystonia. |
2003-05-01 |
2023-08-12 |
Not clear |
| Svetlana I Chefer, Edythe D London, Andrei O Koren, Olga A Pavlova, Varughese Kurian, Alane S Kimes, Andrew G Horti, Alexey G Mukhi. Graphical analysis of 2-[18F]FA binding to nicotinic acetylcholine receptors in rhesus monkey brain. Synapse (New York, N.Y.). vol 48. issue 1. 2003-04-23. PMID:12557269. |
binding potential (bp) values of 2.0, 0.4, 0.3, and 0.03 observed in the thalamus (th), cortex (cx), striatum (str), and cerebellum (cb), respectively, were consistent with the pattern of alpha(4)beta(2) nachr distribution in monkey brain. |
2003-04-23 |
2023-08-12 |
human |
| Amitava Das, Madhu Dikshit, Shoba R Srivastava, Umesh K Srivastava, Chandishwar Nat. Effect of ovariectomy and estrogen supplementation on brain acetylcholinesterase activity and passive-avoidance learning in rats. Canadian journal of physiology and pharmacology. vol 80. issue 9. 2003-04-16. PMID:12430986. |
specific activity of acetylcholinesterase was assayed spectrophotometrically in salt-soluble and detergent-soluble fractions of various brain areas: frontal cortex, cerebral cortex, striatum, hippocampus and hypothalamus, thalamus, pons, medulla, and cerebellum. |
2003-04-16 |
2023-08-12 |
rat |
| Nathalie Ginovart, Alan A Wilson, Jeffrey H Meyer, Doug Hussey, Sylvain Houl. [11C]-DASB, a tool for in vivo measurement of SSRI-induced occupancy of the serotonin transporter: PET characterization and evaluation in cats. Synapse (New York, N.Y.). vol 47. issue 2. 2003-03-06. PMID:12454950. |
the in vivo distribution of [(11)c]-dasb binding was consistent with the known distribution of sert sites in the cat brain in vitro with high uptakes of radioactivity in the midbrain and thalamus, intermediate levels in striatum, and modest to low levels of radioactivity in the neocortex and cerebellum, respectively. |
2003-03-06 |
2023-08-12 |
cat |
| Zoltán Pfund, Diane C Chugani, Otto Muzik, Csaba Juhász, Michael E Behen, Jennifer Lee, Pulak Chakraborty, Thomas Mangner, Harry T Chugan. Alpha[11C] methyl-L-typtophan positron emission tomography in patients with alternating hemiplegia of childhood. Journal of child neurology. vol 17. issue 4. 2003-01-02. PMID:12088079. |
patients with alternating hemiplegia of childhood studied in the ictal or postictal state showed increased serotonin synthesis capacity in the frontoparietal cortex, lateral and medial temporal structures, striatum, and thalamus when compared to controls, and subjects with alternating hemiplegia of childhood studied interictally. |
2003-01-02 |
2023-08-12 |
human |
| María-Trinidad Herrero, Carlos Barcia, Juana Mari Navarr. Functional anatomy of thalamus and basal ganglia. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. vol 18. issue 8. 2002-12-31. PMID:12192499. |
the striatum (caudate nucleus, putamen and nucleus accumbens) receive inputs from all cortical areas and, throughout the thalamus, project principally to frontal lobe areas (prefrontal, premotor and supplementary motor areas) which are concerned with motor planning. |
2002-12-31 |
2023-08-12 |
human |
| Steven L O'Donnell, Terra J Frederick, J Kyle Krady, Susan J Vannucci, Teresa L Woo. IGF-I and microglia/macrophage proliferation in the ischemic mouse brain. Glia. vol 39. issue 1. 2002-08-23. PMID:12112378. |
a period of 20 min of h/i that resulted in histopathology in cortex, striatum, and thalamus was correlated with induction of mrna for igf-i, igfbp-2, igfbp-3, igfbp-5, and glial fibrillary acidic protein (gfap) by 4 days of recovery. |
2002-08-23 |
2023-08-12 |
mouse |