All Relations between prefrontal cortex and serotonin

Publication Sentence Publish Date Extraction Date Species
Maria Becker, Karin Abaev, Elena Shmerkin, Liza Weinstein-Fudim, Albert Pinhasov, Asher Orno. Prenatal SAMe Treatment Induces Changes in Brain Monoamines and in the Expression of Genes Related to Monoamine Metabolism in a Mouse Model of Social Hierarchy and Depression, Probably via an Epigenetic Mechanism. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36233200. same increased the levels of serotonin in the pfc of female sub mice but not in males. 2022-10-14 2023-08-14 mouse
Paolo Tucci, Maria Bove, Vladyslav Sikora, Stefania Dimonte, Maria Grazia Morgese, Stefania Schiavone, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Luigia Trabac. Glucoraphanin Triggers Rapid Antidepressant Responses in a Rat Model of Beta Amyloid-Induced Depressive-like Behaviour. Pharmaceuticals (Basel, Switzerland). vol 15. issue 9. 2022-09-23. PMID:36145275. behavioural analyses were accompanied by neurochemical and biochemical measurements in the prefrontal cortex (pfc), such as serotonin (5-ht), noradrenaline (na), kynurenine (kyn), tryptophan (trp), reactive oxygen species (ros) and the transcription nuclear factor kappa b (nf-kb) levels. 2022-09-23 2023-08-14 rat
Paolo Tucci, Maria Bove, Vladyslav Sikora, Stefania Dimonte, Maria Grazia Morgese, Stefania Schiavone, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Luigia Trabac. Glucoraphanin Triggers Rapid Antidepressant Responses in a Rat Model of Beta Amyloid-Induced Depressive-like Behaviour. Pharmaceuticals (Basel, Switzerland). vol 15. issue 9. 2022-09-23. PMID:36145275. we reported that gra administration in naïve rats at the dose of 50 mg/kg reduced the immobility frequency in the fst and increased 5-ht and na levels in the pfc compared to controls. 2022-09-23 2023-08-14 rat
Paolo Tucci, Maria Bove, Vladyslav Sikora, Stefania Dimonte, Maria Grazia Morgese, Stefania Schiavone, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Luigia Trabac. Glucoraphanin Triggers Rapid Antidepressant Responses in a Rat Model of Beta Amyloid-Induced Depressive-like Behaviour. Pharmaceuticals (Basel, Switzerland). vol 15. issue 9. 2022-09-23. PMID:36145275. at the same dose, gra reverted depressive-like effects of saβ 1-42 administration, restored the 5-ht levels and reduced nf-kb, kyn and ros levels in pfc. 2022-09-23 2023-08-14 rat
Bernardo Lopez-Torres, Irma Ares, Marta Martínez, Jorge-Enrique Maximiliano, María-Rosa Martínez-Larrañaga, Arturo Anadón, María-Aránzazu Martíne. Neurotoxicity induced by the pyrethroid lambda-cyhalothrin: Alterations in monoaminergic systems and dopaminergic and serotoninergic pathways in the rat brain. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2022-09-20. PMID:36126889. the effects of type ii pyrethroid lambda-cyhalothrin on dopamine (da) and serotonin (5-ht) synthesis in rat brain regions (striatum, hippocampus, prefrontal cortex, hypothalamus and midbrain) were studied. 2022-09-20 2023-08-14 rat
Bernardo Lopez-Torres, Irma Ares, Marta Martínez, Jorge-Enrique Maximiliano, María-Rosa Martínez-Larrañaga, Arturo Anadón, María-Aránzazu Martíne. Neurotoxicity induced by the pyrethroid lambda-cyhalothrin: Alterations in monoaminergic systems and dopaminergic and serotoninergic pathways in the rat brain. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2022-09-20. PMID:36126889. the major decreases in da and 5-ht contents were observed in hippocampus and prefrontal cortex tissues. 2022-09-20 2023-08-14 rat
Bernardo Lopez-Torres, Irma Ares, Marta Martínez, Jorge-Enrique Maximiliano, María-Rosa Martínez-Larrañaga, Arturo Anadón, María-Aránzazu Martíne. Neurotoxicity induced by the pyrethroid lambda-cyhalothrin: Alterations in monoaminergic systems and dopaminergic and serotoninergic pathways in the rat brain. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2022-09-20. PMID:36126889. this research study also showed in hippocampus and prefrontal cortex, that lambda-cyhalothrin modified the mrna levels of da transporter gene (dat1 up-regulation), 5-ht transporter gene (sert down-regulation), da receptor genes (drd1and drd2 down-regulation), 5-ht receptor genes (5-ht1a and 5-ht2a down-regulation/up-regulation), da synthesis gene (th down-regulation), 5-ht synthesis gene (tph2 down-regulation), da and 5-ht degradation genes (maoa and maob up-regulation). 2022-09-20 2023-08-14 rat
Diana Serra, Joana F Henriques, Fábio J Sousa, Mariana Laranjo, Rosa Resende, Marisa Ferreira-Marques, Victor de Freitas, Gabriela Silva, João Peça, Teresa C P Dinis, Leonor M Almeid. Attenuation of Autism-like Behaviors by an Anthocyanin-Rich Extract from Portuguese Blueberries via Microbiota-Gut-Brain Axis Modulation in a Valproic Acid Mouse Model. International journal of molecular sciences. vol 23. issue 16. 2022-08-26. PMID:36012528. our data suggested that the are treatment alleviated autism-like behaviors in in utero vpa-exposed mice and, at the same time, decreased both neuroinflammation and gut inflammation, modulated the gut microbiota composition, increased serotonin levels in cerebral prefrontal cortex and gut, and reduced the synaptic dysfunction verified in autistic mice. 2022-08-26 2023-08-14 mouse
Takahiro Maekawa, Naoyoshi Sakitani, Youngjae Ryu, Atsushi Takashima, Shuhei Murase, Julius Fink, Motoshi Nagao, Toru Ogata, Masahiro Shinohara, Yasuhiro Sawad. Application of Passive Head Motion to Generate Defined Accelerations at the Heads of Rodents. Journal of visualized experiments : JoVE. issue 185. 2022-08-08. PMID:35938802. by using this system, it was demonstrated that phm recapitulates the serotonin (5-hydroxytryptamine, hereafter referred to as 5-ht) receptor subtype 2a (5-ht2a) signaling in the prefrontal cortex (pfc) neurons of mice. 2022-08-08 2023-08-14 mouse
Yongxiang Li, Shuqing Zhu, Kailai Xie, Xiajie Feng, Lvshuang Chen, Xin Wu, Zhonghua Sun, Gang Shu, Songbo Wang, Canjun Zhu, Ping Gao, Qingyan Jiang, Lina Wan. TLR4 in Tph2 neurons modulates anxiety-related behaviors in a sex-dependent manner. Neuropharmacology. 2022-07-05. PMID:35787402. tph2 is a rate-limiting enzyme for 5-ht biosynthesis that is expressed at high levels in the drn, which includes the main 5-ht projection to the hippocampus and prefrontal cortex and regulates anxiety disorder. 2022-07-05 2023-08-14 mouse
Khurshid Jalal, Faisal Khan, Shazia Nawaz, Rushda Afroz, Kanwal Khan, Sadia Basharat Ali, Liangliang Hao, Saeed Ahmad Khan, Mohsin Kazi, Reaz Uddin, Darakhshan Jabeen Halee. Anxiolytic, anti-nociceptive and body weight reducing effects of L-lysine in rats: Relationship with brain serotonin an In-Vivo and In-Silico study. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 152. 2022-06-13. PMID:35696944. 5-hydroxytryptamine (5-ht, serotonin) metabolism, and tryptophan (trp) levels in the midbrain (mb), hippocampus (hp), and prefrontal cortex (pfc) were also determined. 2022-06-13 2023-08-14 rat
Khurshid Jalal, Faisal Khan, Shazia Nawaz, Rushda Afroz, Kanwal Khan, Sadia Basharat Ali, Liangliang Hao, Saeed Ahmad Khan, Mohsin Kazi, Reaz Uddin, Darakhshan Jabeen Halee. Anxiolytic, anti-nociceptive and body weight reducing effects of L-lysine in rats: Relationship with brain serotonin an In-Vivo and In-Silico study. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 152. 2022-06-13. PMID:35696944. repeated administration of l-lys increased 5-ht levels in the pfc and hp. 2022-06-13 2023-08-14 rat
Khurshid Jalal, Faisal Khan, Shazia Nawaz, Rushda Afroz, Kanwal Khan, Sadia Basharat Ali, Liangliang Hao, Saeed Ahmad Khan, Mohsin Kazi, Reaz Uddin, Darakhshan Jabeen Halee. Anxiolytic, anti-nociceptive and body weight reducing effects of L-lysine in rats: Relationship with brain serotonin an In-Vivo and In-Silico study. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 152. 2022-06-13. PMID:35696944. trp, the precourser of 5-ht, decreased in the pfc. 2022-06-13 2023-08-14 rat
Khurshid Jalal, Faisal Khan, Shazia Nawaz, Rushda Afroz, Kanwal Khan, Sadia Basharat Ali, Liangliang Hao, Saeed Ahmad Khan, Mohsin Kazi, Reaz Uddin, Darakhshan Jabeen Halee. Anxiolytic, anti-nociceptive and body weight reducing effects of L-lysine in rats: Relationship with brain serotonin an In-Vivo and In-Silico study. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 152. 2022-06-13. PMID:35696944. these beneficial effects were associated with an increase in 5-ht levels in the pfc and hp. 2022-06-13 2023-08-14 rat
Tingting Yang, Yue Li, Hui Wang, Peng Shi, Liu Teng, Haibo Guo, Xiaohua Tu, Xinyu Ya. The 5-HT and PLC Signaling Pathways Regulate the Secretion of IL-1 Evidence-based complementary and alternative medicine : eCAM. vol 2022. 2022-05-23. PMID:35600957. the co-localization of ng2 cells and 5-ht in rat prefrontal cortex was determined using immunofluorescence. 2022-05-23 2023-08-13 rat
J F Morici, G Cicuttin, A Silva, F T Gallo, M Miranda, M Beluscio, C Zold, P Bekinschtein, N V Weisstau. Serotonin type 2a receptor in the prefrontal cortex controls perirhinal cortex excitability during object recognition memory recall. Neuroscience. 2022-05-21. PMID:35597334. serotonin type 2a receptor in the prefrontal cortex controls perirhinal cortex excitability during object recognition memory recall. 2022-05-21 2023-08-13 Not clear
Jinxing Li, Fangfang Pu, Chenrui Peng, Yimei Wang, Yujie Zhang, Simou Wu, Silu Wang, Xi Shen, Ruyue Cheng, Fang H. Antibiotic cocktail-induced gut microbiota depletion in different stages could cause host cognitive impairment and emotional disorders in adulthood in different manners. Neurobiology of disease. 2022-05-19. PMID:35588989. gut microbiota depletion in adolescence resulted in anxiety-like behaviors, short-term memory decline, decreased serum interferon-γ (ifn-γ), mrna expression of 5-hydroxytryptamine receptor 1a, and neuropeptide y receptor y2 in the prefrontal cortex of adult mice. 2022-05-19 2023-08-13 mouse
Keren Nitzan, Dekel David, Motty Franko, Roni Toledano, Sharon Fidelman, Yaarit Simchon Tenenbaum, Maya Blonder, Shir Armoza-Eilat, Alon Shamir, Moshe Rehavi, Yair Ben-Chaim, Ravid Doro. Anxiolytic and antidepressants' effect of Crataegus pinnatifida (Shan Zha): biochemical mechanisms. Translational psychiatry. vol 12. issue 1. 2022-05-19. PMID:35589704. chronic treatment with shan zha did not alter serotonin transporter levels in the pfc, as opposed to escitalopram treatment. 2022-05-19 2023-08-13 mouse
Christopher J O'Connell, Evan L Reeder, Roman A Caceres, Sean M Collins, Kyla Q Chilton, Gary A Gudelsky, Matthew J Robso. Closed Head Traumatic Brain Injury Drives Protracted Inflammation and Remodeling of Serotonergic Architecture in the Dorsal Raphe Nucleus. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554019. no effect of mtbi on 5-ht or 5hiaa levels were found in prefrontal cortex (pfc) or somatosensory cortex (ssc), areas of high 5-ht innervation. 2022-05-13 2023-08-13 mouse
Tara P Cominski, Victoria Stiritz, Kevin D Bec. The Effects of Mild Traumatic Brain Injury (mTBI) on Serotonergic Gene Expression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554362. the hypothesis states that mtbi leads to altered expression of serotonin related genes in the raphe nuclei and/or raphe nuclei target regions including the prefrontal cortex, frontal cortex, and hippocampus. 2022-05-13 2023-08-13 human