| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rachel D Penrod, Jaswinder Kumar, Laura N Smith, Daniel McCalley, Todd B Nentwig, Brandon W Hughes, Gabriella M Barry, Kelsey Glover, Makoto Taniguchi, Christopher W Cowa. Activity-regulated cytoskeleton-associated protein (Arc/Arg3.1) regulates anxiety- and novelty-related behaviors. Genes, brain, and behavior. vol 18. issue 7. 2020-01-16. PMID:30761730. |
we find that stress upregulates arc expression in the adult mouse nucleus accumbens (nac)-a brain region implicated in mood and anxiety behaviors. |
2020-01-16 |
2023-08-13 |
mouse |
| J C Mauna, S S Harris, J A Pino, C M Edwards, M R DeChellis-Marks, C D Bassi, J Garcia-Olivares, S G Amara, F G Guajardo, R Sotomayor-Zarate, M Terminel, E Castañeda, M Vergara, T Baust, E Thiels, G E Torre. G protein βγ subunits play a critical role in the actions of amphetamine. Translational psychiatry. vol 9. issue 1. 2020-01-15. PMID:30745563. |
here, we investigated the role of gβγ in the actions of amphetamine in da neurons in culture, ex vivo nucleus accumbens (nac), and freely moving rats. |
2020-01-15 |
2023-08-13 |
rat |
| M Palmisano, F F Caputi, D Mercatelli, P Romualdi, S Candelett. Dynorphinergic system alterations in the corticostriatal circuitry of neuropathic mice support its role in the negative affective component of pain. Genes, brain, and behavior. vol 18. issue 6. 2020-01-09. PMID:29430855. |
oprk1 gene expression was increased in the pfc, and decreased in the acc and nucleus accumbens (nac). |
2020-01-09 |
2023-08-13 |
mouse |
| Fernando Castillo Díaz, Micaela A Hernandez, Tomas Capellá, Jorge H Medin. Dopamine Neurotransmission in the Ventral Tegmental Area Promotes Active Forgetting of Cocaine-Associated Memory. Molecular neurobiology. vol 56. issue 9. 2020-01-09. PMID:30739236. |
using rodents in the conditioned place preference (cpp) behavioral task, we show that during acquisition d1-type da receptors (d1r) in the vta are crucial components of a neural circuit involving the hippocampus that induces active forgetting of cocaine-associated long-term memory, while vta and nucleus accumbens (nac) d1r are required for its formation. |
2020-01-09 |
2023-08-13 |
Not clear |
| Yong-Sook Park, Francesco Sammartino, Nicole A Young, John Corrigan, Vibhor Krishna, Ali R Reza. Anatomic Review of the Ventral Capsule/Ventral Striatum and the Nucleus Accumbens to Guide Target Selection for Deep Brain Stimulation for Obsessive-Compulsive Disorder. World neurosurgery. vol 126. 2020-01-09. PMID:30790738. |
the ventral capsule/ventral striatum and nucleus accumbens (nac) region is a clinically approved target for deep brain stimulation for obsessive-compulsive disorder. |
2020-01-09 |
2023-08-13 |
Not clear |
| Luis Acaba, David Sidibe, John Thygesen, Harrison Van der Kloot, Laura E Bee. Sex experience increases delta FosB in male and female hamsters, but facilitates sex behavior only in females. Behavioral neuroscience. vol 133. issue 4. 2020-01-09. PMID:30869949. |
repeated experience with motivated behaviors can cause long-lasting structural changes in the nucleus accumbens (nac). |
2020-01-09 |
2023-08-13 |
rat |
| Mary K Estes, Timothy G Freels, William T Prater, Deranda B Leste. Systemic oxytocin administration alters mesolimbic dopamine release in mice. Neuroscience. vol 408. 2020-01-09. PMID:30981861. |
this study investigated the effects of subchronic oxytocin treatments on mesolimbic dopamine transmission in areas associated with anxiety and addiction, the amygdala and the nucleus accumbens (nac), respectively. |
2020-01-09 |
2023-08-13 |
mouse |
| Ruonan Wang, Min Li, Meng Zhao, Dahua Yu, Yu Hu, Corinde E Wiers, Gene-Jack Wang, Nora D Volkow, Kai Yua. Internet gaming disorder: deficits in functional and structural connectivity in the ventral tegmental area-Accumbens pathway. Brain imaging and behavior. vol 13. issue 4. 2020-01-07. PMID:30054871. |
dopamine projections from the ventral tegmental area (vta) to the nucleus accumbens (nac) and from the substantia nigra (sn) to the dorsal striatum are involved in addiction. |
2020-01-07 |
2023-08-13 |
human |
| Stéphanie Trouche, Vadim Koren, Natalie M Doig, Tommas J Ellender, Mohamady El-Gaby, Vítor Lopes-Dos-Santos, Hayley M Reeve, Pavel V Perestenko, Farid N Garas, Peter J Magill, Andrew Sharott, David Dupre. A Hippocampus-Accumbens Tripartite Neuronal Motif Guides Appetitive Memory in Space. Cell. vol 176. issue 6. 2020-01-06. PMID:30773318. |
here, we uncover a direct connection from dorsal ca1 (dca1) hippocampus to nucleus accumbens (nac) that enables the behavioral manifestation of place-reward memories. |
2020-01-06 |
2023-08-13 |
mouse |
| Y Zhang, Y Gao, C-Y Li, W Dong, Y Dong, M-N Li, Y-N Liu, S-L X. Galanin receptor 1 plays an antinociceptive effect via inhibiting PKA activation in the nucleus accumbens of rats with neuropathic pain. Physiological research. vol 68. issue 3. 2020-01-06. PMID:30904004. |
this study investigated the antinociception induced by galanin receptor 1 (galr1) via protein kinase a (pka) signaling pathway in the nucleus accumbens (nac) of rats with neuropathic pain. |
2020-01-06 |
2023-08-13 |
rat |
| Ting Wang, Hong-Li Wang, Rui Liu, Han Wang, Yue Zhang, Ya-Xin Sun, Yun-Ai Su, Tian-Mei Si, Ji-Tao L. Early-life stress alters sleep structure and the excitatory-inhibitory balance in the nucleus accumbens in aged mice. Chinese medical journal. vol 132. issue 13. 2020-01-06. PMID:31045908. |
considering the important role of the nucleus accumbens (nac) in the sleep-wake regulation, this study aimed to assess the effects of early-life stress on the sleep behaviors in aged mice and the potential involvement of the nac in stress-induced sleep abnormalities. |
2020-01-06 |
2023-08-13 |
mouse |
| Mercedes Vega-Villar, Jon C Horvitz, Saleem M Nicol. NMDA receptor-dependent plasticity in the nucleus accumbens connects reward-predictive cues to approach responses. Nature communications. vol 10. issue 1. 2020-01-06. PMID:31562332. |
the nucleus accumbens (nac) is essential for cued approach behavior in trained subjects, and cue-evoked excitations in nac neurons are critical for the expression of this behavior. |
2020-01-06 |
2023-08-13 |
human |
| Chao Dong, Zheng Tian, Kai Zhang, Lijia Chang, Youge Qu, Yaoyu Pu, Qian Ren, Yuko Fujita, Yuta Ohgi, Takashi Futamura, Kenji Hashimot. Increased BDNF-TrkB signaling in the nucleus accumbens plays a role in the risk for psychosis after cannabis exposure during adolescence. Pharmacology, biochemistry, and behavior. vol 177. 2019-12-31. PMID:30629965. |
western blot analysis showed that bdnf-trkb signaling in the nucleus accumbens (nac) of win55,212-2-treated mice were significantly higher than that of vehicle-treated mice. |
2019-12-31 |
2023-08-13 |
mouse |
| Xue Shao, Yunxuan Tang, Hailei Long, Hui Gu, Jie Zhang, Pengchi Deng, Yinglan Zhao, Xiaobo Ce. HMG-CoA synthase 2 drives brain metabolic reprogramming in cocaine exposure. Neuropharmacology. vol 148. 2019-12-27. PMID:28987936. |
here, we profiled the metabolites and metabolic enzymes from brain nucleus accumbens (nac) of mice exposed to cocaine. |
2019-12-27 |
2023-08-13 |
mouse |
| Hang Su, Li Zhu, Jiaqi Li, Rui Wang, Dan Liu, Wei Han, Jean Lud Cadet, Teng Che. Regulation of microRNA-29c in the nucleus accumbens modulates methamphetamine -induced locomotor sensitization in mice. Neuropharmacology. vol 148. 2019-12-27. PMID:30639389. |
changes in microrna (mirna)-mediated gene expression in the nucleus accumbens (nac) may play important roles in regulating drug addiction. |
2019-12-27 |
2023-08-13 |
mouse |
| Ying Zhang, Yi Gao, Chong-Yang Li, Wei Dong, Meng-Nan Li, Ya-Nan Liu, Yan Dong, Shi-Lian X. Galanin plays a role in antinociception via binding to galanin receptors in the nucleus accumbens of rats with neuropathic pain. Neuroscience letters. vol 706. 2019-12-27. PMID:31085289. |
our previous research has shown that the expression of galr1 is upregulated and that galr1 activation in the nucleus accumbens (nac) of rats with neuropathic pain has an antinociceptive effect. |
2019-12-27 |
2023-08-13 |
rat |
| Elizabeth B Smedley, Alyssa DiLeo, Kyle S Smit. Circuit directionality for motivation: Lateral accumbens-pallidum, but not pallidum-accumbens, connections regulate motivational attraction to reward cues. Neurobiology of learning and memory. vol 162. 2019-12-27. PMID:31096040. |
the nucleus accumbens (nac) and ventral pallidum (vp) are two regions involved in cue-driven motivation. |
2019-12-27 |
2023-08-13 |
Not clear |
| E Galaj, B T Kipp, S B Floresco, L M Savag. Persistent Alterations of Accumbal Cholinergic Interneurons and Cognitive Dysfunction after Adolescent Intermittent Ethanol Exposure. Neuroscience. vol 404. 2019-12-24. PMID:30742967. |
here we investigated the effects of binge-like adolescent intermittent ethanol (aie) exposure on nonspatial working memory, behavioral flexibility and cholinergic alterations in the nucleus accumbens (nac) in male and female rats. |
2019-12-24 |
2023-08-13 |
rat |
| Biao Wang, Teng Chen, Li Xue, Jing Wang, Yuwei Jia, Guodong Li, Huixun Ren, Feng Wu, Min Wu, Yanjiong Che. Methamphetamine exacerbates neuroinflammatory response to lipopolysaccharide by activating dopamine D1-like receptors. International immunopharmacology. vol 73. 2019-12-24. PMID:31078920. |
twenty-four hours following the first meth injection, mice were challenged by lipopolysaccharide (lps) at a dose of 330 μg/kg, and the hippocampus (hip), caudate putamen (cpu), nucleus accumbens (nac) and prefrontal cortex (pfc) were collected 4 h after lps administration. |
2019-12-24 |
2023-08-13 |
mouse |
| Jennifer A Martin, Craig T Werner, Swarup Mitra, Ping Zhong, Zi-Jun Wang, Pedro H Gobira, Andrew F Stewart, Jay Zhang, Kyra Erias, Justin N Siemian, Devin Hagarty, Lauren E Mueller, Rachael L Neve, Jun-Xu Li, Ramesh Chandra, Karen C Dietz, Mary Kay Lobo, Amy M Gancarz, Zhen Yan, David M Diet. A novel role for the actin-binding protein drebrin in regulating opiate addiction. Nature communications. vol 10. issue 1. 2019-12-23. PMID:31515501. |
persistent transcriptional and morphological events in the nucleus accumbens (nac) and other brain reward regions contribute to the long-lasting behavioral adaptations that characterize drug addiction. |
2019-12-23 |
2023-08-13 |
Not clear |