| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anthony Klambatsen, Stephanie K Nygard, Anna J Chang, Vanya Quinones, Shirzad Jena. Sex differences in memory and intracellular signaling after methamphetamine binge treatment. Brain research. vol 1711. 2020-08-04. PMID:30629943. |
neurochemical analysis of the same animals indicated higher levels of fosb protein in caudate-putamen (cpu) and nucleus accumbens (nac) of the male animals than intact or ovx females. |
2020-08-04 |
2023-08-13 |
rat |
| Weichen Song, Yifeng Shen, Yanhua Zhang, Sufang Peng, Ran Zhang, Ailing Ning, Huafang Li, Xia Li, Guan Ning Lin, Shunying Y. Expression alteration of microRNAs in Nucleus Accumbens is associated with chronic stress and antidepressant treatment in rats. BMC medical informatics and decision making. vol 19. issue Suppl 6. 2020-08-04. PMID:31856805. |
nucleus accumbens (nac) is a vital brain region for the process of reward and stress, whereas microrna plays a crucial role in depression pathology. |
2020-08-04 |
2023-08-13 |
rat |
| Alan Bo Han He, Chung Lei Huang, Anna Kozłowska, Jun Chien Chen, Chi-Wen Wu, Andrew Chih Wei Huang, Yu Qin Li. Involvement of neural substrates in reward and aversion to methamphetamine addiction: Testing the reward comparison hypothesis and the paradoxical effect hypothesis of abused drugs. Neurobiology of learning and memory. vol 166. 2020-07-28. PMID:31521799. |
the c-fos or p-erk immunohistochemical activity showed that the cingulated cortex area 1 (cg1), infralimbic cortex (il), prelimbic cortex (prl), basolateral amygdala (bla), nucleus accumbens (nac), and dentate gyrus (dg) of the hippocampus were overexpressed in aversive cta induced by methamphetamine. |
2020-07-28 |
2023-08-13 |
Not clear |
| Anum Afzal, Eugene A Kiyatki. Interactions of benzodiazepines with heroin: Respiratory depression, temperature effects, and behavior. Neuropharmacology. vol 158. 2020-07-20. PMID:31228487. |
oxygen levels and brain temperature were assessed with high temporal resolution in the nucleus accumbens (nac), an important structure in the motivational-reinforcement circuit. |
2020-07-20 |
2023-08-13 |
human |
| Giuseppe Aceto, Claudia Colussi, Lucia Leone, Salvatore Fusco, Marco Rinaudo, Federico Scala, Thomas A Green, Fernanda Laezza, Marcello D'Ascenzo, Claudio Grass. Chronic mild stress alters synaptic plasticity in the nucleus accumbens through GSK3β-dependent modulation of Kv4.2 channels. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 14. 2020-07-20. PMID:32209671. |
here, we investigated whether gsk3β activity in the nucleus accumbens (nac) is associated with depression-like behaviors and synaptic plasticity. |
2020-07-20 |
2023-08-13 |
mouse |
| Michelle Corkrum, Ana Covelo, Justin Lines, Luigi Bellocchio, Marc Pisansky, Kelvin Loke, Ruth Quintana, Patrick E Rothwell, Rafael Lujan, Giovanni Marsicano, Eduardo D Martin, Mark J Thomas, Paulo Kofuji, Alfonso Araqu. Dopamine-Evoked Synaptic Regulation in the Nucleus Accumbens Requires Astrocyte Activity. Neuron. vol 105. issue 6. 2020-07-14. PMID:31954621. |
we show that in freely behaving mice, astrocytes in the nucleus accumbens (nac), a key reward center in the brain, respond with ca |
2020-07-14 |
2023-08-13 |
mouse |
| J C de Oliveira, B M B Drabowski, S M A F Rodrigues, R M Maciel, M F D Moraes, V R Cot. Seizure suppression by asynchronous non-periodic electrical stimulation of the amygdala is partially mediated by indirect desynchronization from nucleus accumbens. Epilepsy research. vol 154. 2020-07-13. PMID:31125838. |
further mechanistic investigation using functional magnetic resonance imaging has shown that nps also activates nucleus accumbens (nac) in seizure-free rats, raising the hypothesis of an alternative therapeutic mechanism: nps-enhanced indirect inhibition / desynchronization of ictogenic circuits by nac. |
2020-07-13 |
2023-08-13 |
rat |
| Yiheng Tu, Yanzhi Bi, Libo Zhang, Hua Wei, Li H. Mesocorticolimbic Pathways Encode Cue-Based Expectancy Effects on Pain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 2. 2020-07-13. PMID:31694965. |
it has been suggested that reward-related expectations are associated with the activation of the ventral tegmental area (vta), which projects to the striatum (e.g., nucleus accumbens [nac]) and prefrontal cortex (e.g., rostral anterior cingulate cortex [racc]). |
2020-07-13 |
2023-08-13 |
human |
| Marion A Deroche, Olivier Lassalle, Laia Castell, Emmanuel Valjent, Olivier J Manzon. Cell-Type- and Endocannabinoid-Specific Synapse Connectivity in the Adult Nucleus Accumbens Core. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 5. 2020-07-09. PMID:31831522. |
the nucleus accumbens (nac) is a mesocorticolimbic structure that integrates cognitive, emotional and motor functions. |
2020-07-09 |
2023-08-13 |
mouse |
| S Gallegos, B Muñoz, A Araya, L G Aguay. High ethanol sensitive glycine receptors regulate firing in D1 medium spiny neurons in the nucleus accumbens. Neuropharmacology. vol 160. 2020-07-08. PMID:31521620. |
they are also expressed in the nucleus accumbens (nac) where they have been implicated in the release of dopamine from the ventral tegmental area to the nac in the presence of ethanol. |
2020-07-08 |
2023-08-13 |
Not clear |
| Gabriel Heymann, Yong S Jo, Kathryn L Reichard, Naomi McFarland, Charles Chavkin, Richard D Palmiter, Marta E Soden, Larry S Zweife. Synergy of Distinct Dopamine Projection Populations in Behavioral Reinforcement. Neuron. vol 105. issue 5. 2020-07-07. PMID:31879163. |
using mouse genetics, we isolated two populations of dopamine-producing vta neurons with divergent projections to the nucleus accumbens (nac) core and shell. |
2020-07-07 |
2023-08-13 |
mouse |
| Carles Tapias-Espinosa, Cristóbal Río-Álamos, Ana Sánchez-González, Ignasi Oliveras, Daniel Sampedro-Viana, Maria Del Mar Castillo-Ruiz, Toni Cañete, Adolf Tobeña, Alberto Fernández-Terue. Schizophrenia-like reduced sensorimotor gating in intact inbred and outbred rats is associated with decreased medial prefrontal cortex activity and volume. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 11. 2020-07-06. PMID:30986819. |
relevant structures of the cspt circuit were evaluated, such as the medial prefrontal cortex (mpfc), cingulate cortex, hippocampus (hpc), amygdala, nucleus accumbens (nac), and dorsal striatum. |
2020-07-06 |
2023-08-13 |
rat |
| Hyungwoo Nam, Ramesh Chandra, T Chase Francis, Caroline Dias, Joseph F Cheer, Mary Kay Lob. Reduced nucleus accumbens enkephalins underlie vulnerability to social defeat stress. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 11. 2020-07-06. PMID:31132785. |
enkephalins, endogenous ligands for delta opioid receptors (dors), are highly enriched in the nucleus accumbens (nac). |
2020-07-06 |
2023-08-13 |
mouse |
| Kevin M Manz, Andrew G Baxley, Zack Zurawski, Heidi E Hamm, Brad A Gruete. Heterosynaptic GABA The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 47. 2020-07-01. PMID:31578230. |
heterosynaptic gaba complex circuit interactions within the nucleus accumbens (nac) facilitate goal-directed behavior. |
2020-07-01 |
2023-08-13 |
Not clear |
| Lindsay Naef, Lauren Seabrook, Jeff Hsiao, Calvin Li, Stephanie L Borglan. Insulin in the ventral tegmental area reduces cocaine-evoked dopamine in the nucleus accumbens in vivo. The European journal of neuroscience. vol 50. issue 3. 2020-06-30. PMID:30471157. |
whether insulin directly targets the vta to alter dopamine release in projection areas, such as the nucleus accumbens (nac), remains unknown. |
2020-06-30 |
2023-08-13 |
Not clear |
| Robert A Waeiss, Christopher P Knight, Eric A Engleman, Sheketha R Hauser, Zachary A Rod. Co-administration of ethanol and nicotine heightens sensitivity to ethanol reward within the nucleus accumbens (NAc) shell and increasing NAc shell BDNF is sufficient to enhance ethanol reward in naïve Wistar rats. Journal of neurochemistry. vol 152. issue 5. 2020-06-30. PMID:31721205. |
co-administration of ethanol and nicotine heightens sensitivity to ethanol reward within the nucleus accumbens (nac) shell and increasing nac shell bdnf is sufficient to enhance ethanol reward in naïve wistar rats. |
2020-06-30 |
2023-08-13 |
rat |
| Robert A Waeiss, Christopher P Knight, Eric A Engleman, Sheketha R Hauser, Zachary A Rod. Co-administration of ethanol and nicotine heightens sensitivity to ethanol reward within the nucleus accumbens (NAc) shell and increasing NAc shell BDNF is sufficient to enhance ethanol reward in naïve Wistar rats. Journal of neurochemistry. vol 152. issue 5. 2020-06-30. PMID:31721205. |
drug exposure through direct infusion into the posterior ventral tegmental area (pvta) stimulated release of glutamate and dopamine in the nucleus accumbens (nac) shell, which was quantified through high-performance liquid chromatography. |
2020-06-30 |
2023-08-13 |
rat |
| Soonje Lee, Changwoo Lee, Changsu Woo, Shin Jung Kang, Ki Soon Shi. Chronic social defeat stress increases burst firing of nucleus accumbens-projecting ventral subicular neurons in stress-susceptible mice. Biochemical and biophysical research communications. vol 515. issue 3. 2020-06-29. PMID:31167722. |
here, we found that neurons in the proximal vsub projected to the nucleus accumbens (nac). |
2020-06-29 |
2023-08-13 |
mouse |
| Meriem Haddar, Kyosuke Uno, Kohei Hamatani, Shin-Ichi Muramatsu, Atsumi Nitt. Regulatory system of mGluR group II in the nucleus accumbens for methamphetamine-induced dopamine increase by the medial prefrontal cortex. Neuropsychopharmacology reports. vol 39. issue 3. 2020-06-29. PMID:31283871. |
shati/nat8l overexpression in the mpfc expressed lower levels of both glutamate and dopamine (da) in the nucleus accumbens (nac) and attenuated meth-induced da elevation. |
2020-06-29 |
2023-08-13 |
Not clear |
| Lisamon Egenrieder, Ekaterina Mitricheva, Rainer Spanagel, Hamid R Noor. No basal or drug-induced sex differences in striatal dopaminergic levels: a cluster and meta-analysis of rat microdialysis studies. Journal of neurochemistry. vol 152. issue 4. 2020-06-29. PMID:31705667. |
all drugs of abuse, independent of their molecular mechanisms of action, notably increase extracellular dopamine concentrations in the nucleus accumbens (nac) and caudate putamen (cpu). |
2020-06-29 |
2023-08-13 |
rat |