| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Javier A Muñiz, José P Prieto, Betina González, Máximo H Sosa, Jean L Cadet, Cecilia Scorza, Francisco J Urbano, Verónica Bisagn. Cocaine and Caffeine Effects on the Conditioned Place Preference Test: Concomitant Changes on Early Genes within the Mouse Prefrontal Cortex and Nucleus Accumbens. Frontiers in behavioral neuroscience. vol 11. 2020-09-30. PMID:29093669. |
the goal of the present study was thus to determine caffeine and cocaine combined effects on the conditioned place preference (cpp) test and to determine potential differential mrna expression in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) of immediate-early genes (iegs) as well as dopamine and adenosine receptor subunits. |
2020-09-30 |
2023-08-13 |
mouse |
| Josephine R Tarren, Henry A Lester, Arnauld Belmer, Selena E Bartlet. Acute Ethanol Administration Upregulates Synaptic α4-Subunit of Neuronal Nicotinic Acetylcholine Receptors within the Nucleus Accumbens and Amygdala. Frontiers in molecular neuroscience. vol 10. 2020-09-30. PMID:29114204. |
in the present study, we measured the effect of acute binge ethanol on nachr α4 subunit levels in the prefrontal cortex (pfc), nucleus accumbens (nac), ventral tegmental area (vta), and amygdala (amg) by western blot analysis using a knock-in mouse line, generated with a normally functioning α4 nachr subunit tagged with yellow fluorescent protein (yfp). |
2020-09-30 |
2023-08-13 |
mouse |
| Ahmed Hasbi, Melissa L Perreault, Maurice Y F Shen, Theresa Fan, Tuan Nguyen, Mohammed Alijaniaram, Tomek J Banasikowski, Anthony A Grace, Brian F O'Dowd, Paul J Fletcher, Susan R Georg. Activation of Dopamine D1-D2 Receptor Complex Attenuates Cocaine Reward and Reinstatement of Cocaine-Seeking through Inhibition of DARPP-32, ERK, and ΔFosB. Frontiers in pharmacology. vol 8. 2020-09-30. PMID:29354053. |
a significant subpopulation of neurons in rat nucleus accumbens (nac) coexpress dopamine d1 and d2 receptors, which can form a d1-d2 receptor complex, but their relevance in addiction is not known. |
2020-09-30 |
2023-08-13 |
rat |
| Canan B Peisker, Thomas Schüller, Jan Peters, Ben J Wagner, Leonhard Schilbach, Ulf J Müller, Veerle Visser-Vandewalle, Jens Kuh. Nucleus Accumbens Deep Brain Stimulation in Patients with Substance Use Disorders and Delay Discounting. Brain sciences. vol 8. issue 2. 2020-09-30. PMID:29382059. |
deep brain stimulation (dbs) of the nucleus accumbens (nac) shows first promising results in patients with severe substance use disorder (sud), a patient group known to have deficits in self-control. |
2020-09-30 |
2023-08-13 |
Not clear |
| Ju Hwan Yang, Su Yeon Seo, Jeong Hwan Oh, In Soo Ryu, Jieun Kim, Dong Kun Lee, Yeonhee Ryu, Eun Sang Cho. Activation of Protein Kinase G After Repeated Cocaine Administration Is Necessary for the Phosphorylation of α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptor GluA1 at Serine 831 in the Rat Nucleus Accumbens. Frontiers in molecular neuroscience. vol 11. 2020-09-30. PMID:30104957. |
the present study determined if activation of protein kinase g (pkg) contributes to the phosphorylation of ampa receptor glua1 subunit at the position of serine 831 (glua1-s831) in the rat nucleus accumbens (nac) after repeated cocaine administration. |
2020-09-30 |
2023-08-13 |
rat |
| Wilder T Doucette, Lucas Dwiel, Jared E Boyce, Amanda A Simon, Jibran Y Khokhar, Alan I Gree. Machine Learning Based Classification of Deep Brain Stimulation Outcomes in a Rat Model of Binge Eating Using Ventral Striatal Oscillations. Frontiers in psychiatry. vol 9. 2020-09-30. PMID:30123143. |
here, sprague-dawley rats received deep brain stimulation separately within each nucleus accumbens (nac) sub-region (core and shell) using a within-animal crossover design in a rat model of binge eating. |
2020-09-30 |
2023-08-13 |
rat |
| Anze Testen, Marian T Sepulveda-Orengo, Christiann H Gaines, Kathryn J Reissne. Region-Specific Reductions in Morphometric Properties and Synaptic Colocalization of Astrocytes Following Cocaine Self-Administration and Extinction. Frontiers in cellular neuroscience. vol 12. 2020-09-30. PMID:30147645. |
we recently showed that astrocytes within the nucleus accumbens (nac) core exhibit decreased volume, surface area, and synaptic colocalization following cocaine self-administration and extinction, compared to nac astrocytes from saline-administering animals (scofield et al., 2016b). |
2020-09-30 |
2023-08-13 |
rat |
| Kellie S Gross, Kelsey M Moore, Robert L Meisel, Paul G Mermelstei. mGluR5 Mediates Dihydrotestosterone-Induced Nucleus Accumbens Structural Plasticity, but Not Conditioned Reward. Frontiers in neuroscience. vol 12. 2020-09-30. PMID:30515075. |
a commonality between gonadal hormones and drugs of abuse is that they both impact the neurocircuitry of reward, including the regulation of structural plasticity in the nucleus accumbens (nac). |
2020-09-30 |
2023-08-13 |
rat |
| Kristen A McLaurin, Anna K Cook, Hailong Li, Alexis F League, Charles F Mactutus, Rosemarie M Booz. Synaptic Connectivity in Medium Spiny Neurons of the Nucleus Accumbens: A Sex-Dependent Mechanism Underlying Apathy in the HIV-1 Transgenic Rat. Frontiers in behavioral neuroscience. vol 12. 2020-09-30. PMID:30524255. |
behavioral and neurochemical indices of apathy in the nucleus accumbens (nac), a key brain region involved in frontal-subcortical circuitry, are influenced by the factor of biological sex. |
2020-09-30 |
2023-08-13 |
human |
| Genghong Tu, Li Ying, Liuzhen Ye, Jinlan Zhao, Nuyun Liu, Juan Li, Yutong Liu, Mengjuan Zhu, Yue Wu, Bin Xiao, Huidong Guo, Fukun Guo, Huijun Wang, Lin Zhang, Lu Zhan. Dopamine D Biological psychiatry. vol 86. issue 11. 2020-09-30. PMID:31060803. |
dopamine d methamphetamine (meth) is a highly addictive psychostimulant that strongly activates dopamine receptor signaling in the nucleus accumbens (nac). |
2020-09-30 |
2023-08-13 |
Not clear |
| Robert Hitzemann, Ovidiu D Iancu, Cheryl Reed, Harue Baba, Denesa R Lockwood, Tamara J Phillip. Regional Analysis of the Brain Transcriptome in Mice Bred for High and Low Methamphetamine Consumption. Brain sciences. vol 9. issue 7. 2020-09-30. PMID:31262025. |
three brain reward circuitry regions were explored, the nucleus accumbens (nac), prefrontal cortex (pfc), and ventral midbrain (vmb). |
2020-09-30 |
2023-08-13 |
mouse |
| Ann Mary Iturra-Mena, Marcelo Aguilar-Rivera, Marcia Arriagada-Solimano, Catherine Pérez-Valenzuela, Pablo Fuentealba, Alexies Dagnino-Subiabr. Impact of Stress on Gamma Oscillations in the Rat Nucleus Accumbens During Spontaneous Social Interaction. Frontiers in behavioral neuroscience. vol 13. 2020-09-30. PMID:31354444. |
social behavior is modulated by the reward system, and gamma oscillations in the nucleus accumbens (nac) seem to be associated with reward processing. |
2020-09-30 |
2023-08-13 |
rat |
| Marc T Pisansky, Emilia M Lefevre, Cassandra L Retzlaff, Brian H Trieu, David W Leipold, Patrick E Rothwel. Nucleus Accumbens Fast-Spiking Interneurons Constrain Impulsive Action. Biological psychiatry. vol 86. issue 11. 2020-09-30. PMID:31471038. |
the nucleus accumbens (nac) controls multiple facets of impulsivity but is a heterogeneous brain region with diverse microcircuitry. |
2020-09-30 |
2023-08-13 |
Not clear |
| Suchan Chang, Yeonhee Ryu, Yu Fan, Se Kyun Bang, Nam Jun Kim, Jin Gyeom Lee, Jin Mook Kim, Bong Hyo Lee, Chae Ha Yang, Hee Young Ki. Involvement of the Cuneate Nucleus in the Acupuncture Inhibition of Drug-Seeking Behaviors. Frontiers in neuroscience. vol 13. 2020-09-30. PMID:31555084. |
our previous studies have shown that acupuncture suppresses addictive behaviors induced by drugs of abuse, including cocaine, morphine and ethanol, by modulating gaba neurons in the ventral tegmental area (vta) and dopamine (da) release in the nucleus accumbens (nac). |
2020-09-30 |
2023-08-13 |
Not clear |
| Kenneth Blum, Rajendra D Badgaiyan, Eric R Braverman, Kristina Dushaj, Mona Li, Peter K Thanos, Zsolt Demetrovics, Marcelo Feb. Hypothesizing that, A Pro-Dopamine Regulator (KB220Z) Should Optimize, but Not Hyper-Activate the Activity of Trace Amine-Associated Receptor 1 (TAAR-1) and Induce Anti-Craving of Psychostimulants in the Long-Term. Journal of reward deficiency syndrome and addiction science. vol 2. issue 1. 2020-09-29. PMID:28317038. |
it is also well accepted that psychostimulants such as cocaine affect not only the release of neuronal dopamine at the nucleus accumbens (nac), but also has powerful inhibitory actions on the dopamine transporter system. |
2020-09-29 |
2023-08-13 |
Not clear |
| ChengPeng Yu, XiaoYan Zhou, Qiang Fu, QingHua Peng, Ki-Wan Oh, ZhenZhen H. A New Insight into the Role of CART in Cocaine Reward: Involvement of CaMKII and Inhibitory G-Protein Coupled Receptor Signaling. Frontiers in cellular neuroscience. vol 11. 2020-09-29. PMID:28860971. |
cocaine- and amphetamine-regulated transcript (cart) peptides are neuropeptides that are expressed in brain regions associated with reward, such as the nucleus accumbens (nac), and play a role in cocaine reward. |
2020-09-29 |
2023-08-13 |
Not clear |
| Chencheng Zhang, Dianyou Li, Haiyan Jin, Kristina Zeljic, Bomin Su. Target-specific deep brain stimulation of the ventral capsule/ventral striatum for the treatment of neuropsychiatric disease. Annals of translational medicine. vol 5. issue 20. 2020-09-29. PMID:29152502. |
according to the anatomical features of the vc/vs, a novel electrode was developed for simultaneous and independently programmed stimulation of the nucleus accumbens (nac) and the anterior limb of the internal capsule (alic). |
2020-09-29 |
2023-08-13 |
Not clear |
| Jingjing Cheng, Jincheng Wang, Xiaolin Ma, Rahim Ullah, Yi Shen, Yu-Dong Zho. Anterior Paraventricular Thalamus to Nucleus Accumbens Projection Is Involved in Feeding Behavior in a Novel Environment. Frontiers in molecular neuroscience. vol 11. 2020-09-29. PMID:29930498. |
notably, the pvt neurons projecting to the nucleus accumbens (nac) are activated when an incentive stimulus is presented. |
2020-09-29 |
2023-08-13 |
mouse |
| Yuan Zhou, Hao-Kang Zhang, Fei Liu, Gang Lei, Peng Liu, Tong Jiao, Yong-Hui Dan. Altered Light Conditions Contribute to Abnormalities in Emotion and Cognition Through HINT1 Dysfunction in C57BL/6 Mice. Frontiers in behavioral neuroscience. vol 12. 2020-09-29. PMID:29937721. |
based on the potential links between histidine triad nucleotide binding protein 1 (hint1) and mood disorders, we also examined the expression of hint1 and related apoptosis factors in the suprachiasmatic nucleus (scn), prefrontal cortex (pfc), nucleus accumbens (nac) and hippocampus (hip). |
2020-09-29 |
2023-08-13 |
mouse |
| Vadim Yuferov, Yong Zhang, Yupu Liang, Connie Zhao, Matthew Randesi, Mary J Kree. Oxycodone Self-Administration Induces Alterations in Expression of Integrin, Semaphorin and Ephrin Genes in the Mouse Striatum. Frontiers in psychiatry. vol 9. 2020-09-29. PMID:29946272. |
the aim of this study is to investigate alterations in expression of selected integrin, semaphorin, ephrins, netrin, and slit genes in the nucleus accumbens (nac) and caudate putamen (cpu) of mice following extended 14-day oxycodone self-administration (sa), using rnaseq. |
2020-09-29 |
2023-08-13 |
mouse |