| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jianfeng Liu, Ruyan Wu, Robert Seaman, Kevin M Manz, Bernard Johnson, Jimmy Vu, Yufei Huang, Yanan Zhang, Alfred J Robison, Rachael Neve, Brad A Grueter, David Dietz, Jun-Xu L. TAAR1 regulates drug-induced reinstatement of cocaine-seeking via negatively modulating CaMKIIα activity in the NAc. Molecular psychiatry. 2022-01-26. PMID:35079125. |
we focused on the shell subregion of nucleus accumbens (nac), a key brain region of the brain reward system. |
2022-01-26 |
2023-08-13 |
rat |
| Changliang Zhu, Lei Wang, Jiangwei Ding, Hailiang Li, Din Wan, Yangyang Sun, Baorui Guo, Zhenquan He, Xiaofan Ren, Shucai Jiang, Caibing Gao, Hua Guo, Tao Sun, Feng Wan. Effects of Glucagon-Like Peptide-1 Receptor Agonist Exendin-4 on the Reinstatement of Cocaine-Mediated Conditioned Place Preference in Mice. Frontiers in behavioral neuroscience. vol 15. 2022-01-24. PMID:35069139. |
the expression of nuclear factor κβ (nf-κβ) in the nucleus accumbens (nac) was detected using western blotting. |
2022-01-24 |
2023-08-13 |
mouse |
| Kaoru Kinugawa, Tomoo Mano, Yuya Yamatani, Toshiteru Miyasaka, Hiroshi Kataoka, Kazuma Sugi. Pain-Related Abnormal Neuronal Synchronization of the Nucleus Accumbens in Parkinson's Disease. Brain sciences. vol 12. issue 1. 2022-01-21. PMID:35053828. |
the nucleus accumbens (nac) is a central component of the mesolimbic dopaminergic pathway involved in pain processing. |
2022-01-21 |
2023-08-13 |
Not clear |
| Peng-Bo Jing, Xiao-Hong Chen, Huan-Jun Lu, Yong-Jing Gao, Xiao-Bo W. Enhanced function of NR2C/2D-containing NMDA receptor in the nucleus accumbens contributes to peripheral nerve injury-induced neuropathic pain and depression in mice. Molecular pain. vol 18. 2022-01-21. PMID:35057644. |
n-methyl-d-aspartate receptors (nmdars) dysfunction in the nucleus accumbens (nac) participates in regulating many neurological and psychiatric disorders such as drug addiction, chronic pain, and depression. |
2022-01-21 |
2023-08-13 |
mouse |
| Erika I Araya, Eduardo C Carvalho, Roberto Andreatini, Gerald W Zamponi, Juliana G Chichorr. Trigeminal neuropathic pain causes changes in affective processing of pain in rats. Molecular pain. vol 18. 2022-01-19. PMID:35042377. |
finally, brain tissue was collected to assess the change in tyrosine hydroxylase (th) expression in the nucleus accumbens (nac) and c-fos expression in brain areas involved in emotional pain processing, including the prefrontal cortex (pfc), amygdala, and nac. |
2022-01-19 |
2023-08-13 |
rat |
| Maxine K Loh, Nicole C Ferrara, Jocelyn M Torres, J Amiel Rosenkran. Medial orbitofrontal cortex and nucleus accumbens mediation in risk assessment behaviors in adolescents and adults. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-01-18. PMID:35039643. |
nucleus accumbens (nac) activity is linked to risky decision-making and receives inputs carrying sensory and emotional information. |
2022-01-18 |
2023-08-13 |
rat |
| Bryan W Jenkins, Shoshana Buckhalter, Melissa L Perreault, Jibran Y Khokha. Cannabis Vapor Exposure Alters Neural Circuit Oscillatory Activity in a Neurodevelopmental Model of Schizophrenia: Exploring the Differential Impact of Cannabis Constituents. Schizophrenia bulletin open. vol 3. issue 1. 2022-01-17. PMID:35036917. |
in adulthood, electrodes were implanted targeting the cingulate cortex (cg), the prelimbic cortex (prlc), the hippocampus (hip), and the nucleus accumbens (nac). |
2022-01-17 |
2023-08-13 |
rat |
| Minami Kanai, Ryota Kamiizawa, Natsuko Hitora-Imamura, Masabumi Minam. Exposure to hot and cold environments activates neurons projecting from the paraventricular thalamic nucleus to brain regions related to approach and avoidance behaviors. Journal of thermal biology. vol 103. 2022-01-14. PMID:35027193. |
in this study, to elucidate the neuronal circuits mediating behavioral thermoregulatory responses, we examined whether neuronal pathways from the pvt to the nucleus accumbens (nac), bed nucleus of the stria terminalis (bnst), and central nucleus of the amygdala (cea), which are brain regions implicated in mediating appetitive/approach and aversive/avoidance behaviors, are activated during exposure to hot (38°c) and cold (8°c) environments using c-fos immunostaining and retrograde tracing. |
2022-01-14 |
2023-08-13 |
Not clear |
| Daifeng Dong, Maria Ironside, Emily L Belleau, Xiaoqiang Sun, Chang Cheng, Ge Xiong, Lisa D Nickerson, Xiang Wang, Shuqiao Yao, Diego A Pizzagall. Sex-specific neural responses to acute psychosocial stress in depression. Translational psychiatry. vol 12. issue 1. 2022-01-11. PMID:35013110. |
based on prior studies, amygdala, hippocampus, medial orbitofrontal cortex (mofc), nucleus accumbens (nac) and dorsolateral prefrontal cortex (dlpfc) were selected as a priori regions of interest. |
2022-01-11 |
2023-08-13 |
Not clear |
| Darius D Becker-Krail, Puja K Parekh, Kyle D Ketchesin, Shintaro Yamaguchi, Jun Yoshino, Mariah A Hildebrand, Brandon Dunham, Madhavi K Ganapathiraiu, Ryan W Logan, Colleen A McClun. Circadian Transcription Factor NPAS2 and the NAD+-Dependent Deacetylase SIRT1 Interact in the Mouse Nucleus Accumbens and Regulate Reward. The European journal of neuroscience. 2022-01-10. PMID:35001440. |
in the nucleus accumbens (nac), a region important for reward, both sirt1 and the circadian transcription factor neuronal pas domain protein 2 (npas2) are highly enriched, and both are regulated by the metabolic cofactor nad+. |
2022-01-10 |
2023-08-13 |
mouse |
| Daisuke Sato, Michiko Narita, Yusuke Hamada, Tomohisa Mori, Kenichi Tanaka, Hideki Tamura, Akihiro Yamanaka, Ryosuke Matsui, Dai Watanabe, Yukari Suda, Emiko Senba, Moe Watanabe, Edita Navratilova, Frank Porreca, Naoko Kuzumaki, Minoru Narit. Relief of neuropathic pain by cell-specific manipulation of nucleus accumbens dopamine D1- and D2-receptor-expressing neurons. Molecular brain. vol 15. issue 1. 2022-01-07. PMID:34991655. |
as chronic pain conditions are associated with hypodopaminergic tone in the nucleus accumbens (nac), we evaluated the effects of increasing signaling at dopamine d1/d2-expressing neurons in the nac neurons in a model of neuropathic pain induced by partial ligation of sciatic nerve. |
2022-01-07 |
2023-08-13 |
Not clear |
| Salar Vaseghi, Shahram Zarrabian, Abbas Haghparas. Reviewing the role of the orexinergic system and stressors in modulating mood and reward-related behaviors. Neuroscience and biobehavioral reviews. 2022-01-01. PMID:34973302. |
cross-talk between the reward system and orexinergic signaling was also investigated, especially orexinergic signaling in the ventral tegmental area (vta), the nucleus accumbens (nac), and the hippocampus. |
2022-01-01 |
2023-08-13 |
Not clear |
| Marie-Charlotte Allichon, Vanesa Ortiz, Paula Pousinha, Andry Andrianarivelo, Anna Petitbon, Nicolas Heck, Pierre Trifilieff, Jacques Barik, Peter Vanhoutt. Cell-Type-Specific Adaptions in Striatal Medium-Sized Spiny Neurons and Their Roles in Behavioral Responses to Drugs of Abuse. Frontiers in synaptic neuroscience. vol 13. 2021-12-31. PMID:34970134. |
we will therefore conclude this review by examining how the nucleus accumbens (nac) could constitute a key interface between addiction and depression. |
2021-12-31 |
2023-08-13 |
Not clear |
| Hidenari Nomura, Cheol Son, Daisuke Aotani, Yoshiyuki Shimizu, Goro Katsuura, Michio Noguchi, Toru Kusakabe, Tomohiro Tanaka, Takashi Miyazawa, Kiminori Hosoda, Kazuwa Naka. Impaired leptin responsiveness in the nucleus accumbens of leptin-overexpressing transgenic mice with dysregulated sucrose and lipid preference independent of obesity. Neuroscience research. 2021-12-31. PMID:34971637. |
however, compared to wt-cd1w mice, leptg-hfd1w mice exhibited attenuated leptin-induced anorexia, decreased leptin-induced c-fos immunostaining in nucleus accumbens (nac), one of important site of reward system, decreased leptin-stimulated pstat3 immunostaining in hypothalamus. |
2021-12-31 |
2023-08-13 |
mouse |
| Jing Wang, Simin Lai, Rui Wang, Ting Zhou, Nan Dong, Li Zhu, Teng Chen, Xia Zhang, Yanjiong Che. Dopamine D3 Receptor in the Nucleus Accumbens Alleviates Neuroinflammation in a Mouse Model of Depressive-Like Behavior. Brain, behavior, and immunity. 2021-12-31. PMID:34971757. |
nucleus accumbens (nac) inf-lammation is implicated in the development and progression of depression, but its regulatory mechanism remains largely unknown. |
2021-12-31 |
2023-08-13 |
mouse |
| Gregg Wildenberg, Anastasia Sorokina, Jessica Koranda, Alexis Monical, Chad Heer, Mark Sheffield, Xiaoxi Zhuang, Daniel McGehee, Bobby Kasthur. Partial connectomes of labeled dopaminergic circuits reveal non-synaptic communication and axonal remodeling after exposure to cocaine. eLife. vol 10. 2021-12-29. PMID:34965204. |
we leverage cell type-specific labeling with large volume serial electron microscopy to detail da connections in the nucleus accumbens (nac) of the mouse ( |
2021-12-29 |
2023-08-13 |
mouse |
| Isao Nagata, Mika Sasaki, Tomoyuki Miyazaki, Kensuke Saeki, Ken-Ichi Ogawa, Yoshinori Kamiy. Subanesthetic Dose of Propofol Activates the Reward System in Rats. Anesthesia and analgesia. 2021-12-27. PMID:34958308. |
propofol has addictive properties, even with a single administration, and facilitates dopamine secretion in the nucleus accumbens (nac). |
2021-12-27 |
2023-08-13 |
rat |
| Ruyan Wu, Jianfeng Liu, Jimmy Vu, Yufei Huang, David M Dietz, Jun-Xu L. Interleukin-1 receptor-associated kinase 4 (IRAK4) in the nucleus accumbens regulates opioid-seeking behavior in male rats. Brain, behavior, and immunity. 2021-12-27. PMID:34958862. |
we found that morphine self-administration increased the phosphorylation level of irak4 in the nucleus accumbens (nac) in rats; the irak4 signaling remained activated after morphine extinction and cue-induced reinstatement test. |
2021-12-27 |
2023-08-13 |
rat |
| Kevin M Manz, Lillian J Brady, Erin S Calipari, Brad A Gruete. Accumbal Histamine Signaling Engages Discrete Interneuron Microcircuits. Biological psychiatry. 2021-12-26. PMID:34953589. |
central histamine (ha) signaling modulates diverse cortical and subcortical circuits throughout the brain, including the nucleus accumbens (nac). |
2021-12-26 |
2023-08-13 |
Not clear |
| Inês M Amaral, Laura Scheffauer, Angelika B Langeder, Alex Hofer, Rana El Rawa. Rewarding Social Interaction in Rats Increases CaMKII in the Nucleus Accumbens. Biomedicines. vol 9. issue 12. 2021-12-24. PMID:34944702. |
however, little is known about the contribution of camkii signaling in the nucleus accumbens (nac) in natural rewards such as social interaction. |
2021-12-24 |
2023-08-13 |
rat |