| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Berger, S Przedborski, J L Cade. Retrograde degeneration of nigrostriatal neurons induced by intrastriatal 6-hydroxydopamine injection in rats. Brain research bulletin. vol 26. issue 2. 1991-05-16. PMID:1826461. |
there were also significant decreases of dopamine uptake sites in the nucleus accumbens (nac) (-73%) and in the ventral tegmental area (vta) (-70%). |
1991-05-16 |
2023-08-11 |
rat |
| D W Clow, R P Hamme. Cocaine abstinence following chronic treatment alters cerebral metabolism in dopaminergic reward regions. Bromocriptine enhances recovery. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 4. issue 1. 1991-04-22. PMID:2003868. |
cocaine abstinence following chronic treatment significantly reduced lcgu in several regions including mesocorticolimbic structures such as ventral tegmental area, medial prefrontal cortex, and nucleus accumbens (nac). |
1991-04-22 |
2023-08-11 |
rat |
| K Kujirai, S Przedborski, V Kostic, V Jackson-Lewis, S Fahn, J L Cade. Autoradiography of dopamine receptors and dopamine uptake sites in the spontaneously hypertensive rat. Brain research bulletin. vol 25. issue 5. 1991-04-01. PMID:2149666. |
shr showed significantly higher [3h]sch 23390 and [3h]spiperone binding in the caudate-putamen (cpu), the nucleus accumbens (nac) and the olfactory tubercle (ot) in comparison to the sd rats. |
1991-04-01 |
2023-08-11 |
rat |
| N R Swerdlow, D L Braff, M A Geye. GABAergic projection from nucleus accumbens to ventral pallidum mediates dopamine-induced sensorimotor gating deficits of acoustic startle in rats. Brain research. vol 532. issue 1-2. 1991-03-21. PMID:2282510. |
other behavioral changes following mesolimbic da activation are mediated through gabaergic efferent projections from the nucleus accumbens (nac) to the ventral pallidum (vp). |
1991-03-21 |
2023-08-11 |
rat |
| R Spanagel, A Herz, T S Shippenber. The effects of opioid peptides on dopamine release in the nucleus accumbens: an in vivo microdialysis study. Journal of neurochemistry. vol 55. issue 5. 1990-11-20. PMID:1976759. |
accordingly, the present study employed the technique of in vivo microdialysis to examine the effects of selective mu-, delta-, and kappa- opioids on da release in the nucleus accumbens (nac) of anesthetized rats. |
1990-11-20 |
2023-08-11 |
rat |
| P Vezina, J Stewar. Amphetamine administered to the ventral tegmental area but not to the nucleus accumbens sensitizes rats to systemic morphine: lack of conditioned effects. Brain research. vol 516. issue 1. 1990-08-13. PMID:2364286. |
different groups of rats received conditioning training with bilateral injections of amphetamine (2.5 micrograms/0.5 microliters/side) either into the ventral tegmental area (vta) or the nucleus accumbens (nac) and were tested on separate occasions for conditioned locomotor activity with saline and cross-sensitization to the locomotor activating effects of morphine (1.0 mg/kg, i.p.). |
1990-08-13 |
2023-08-11 |
rat |
| L H Jiang, C R Ashby, R J Kasser, R Y Wan. The effect of intraventricular administration of the 5-HT3 receptor agonist 2-methylserotonin on the release of dopamine in the nucleus accumbens: an in vivo chronocoulometric study. Brain research. vol 513. issue 1. 1990-07-17. PMID:2112416. |
in the present study we have examined the effects of the serotonin3 (5-ht3) agonist 2-methylserotonin (2-me-5ht) on the dopamine (da) release in the nucleus accumbens (nac) of rats using in vivo chronocoulometric recording. |
1990-07-17 |
2023-08-11 |
rat |
| J T Qiao, P M Dougherty, R C Wiggins, N Dafn. Effects of microiontophoretic application of cocaine, alone and with receptor antagonists, upon the neurons of the medial prefrontal cortex, nucleus accumbens and caudate nucleus of rats. Neuropharmacology. vol 29. issue 4. 1990-06-27. PMID:2342637. |
the spontaneous extracellular electrical activity of 102 neurons, within the caudate nucleus (cn), medial prefrontal cortex (mpc), nucleus accumbens (nac) and a control site, the lateral thalamic nucleus (lt), was studied. |
1990-06-27 |
2023-08-11 |
rat |
| Y Ishida, T Hashitani, M Kumazaki, T Ikeda, H Nishin. Behavioral and biochemical effects of intra-accumbens dopaminergic grafts. Brain research bulletin. vol 24. issue 3. 1990-06-20. PMID:2110848. |
transplantation of mesencephalic dopaminergic cells, obtained from rat embryos, into the nucleus accumbens (nac) of 6-ohda-lesioned animals restored the hyperactivity 4 weeks after grafting. |
1990-06-20 |
2023-08-11 |
rat |
| J A Angulo, J L Cadet, C S Woolley, F Suber, B S McEwe. Effect of chronic typical and atypical neuroleptic treatment on proenkephalin mRNA levels in the striatum and nucleus accumbens of the rat. Journal of neurochemistry. vol 54. issue 6. 1990-06-18. PMID:1971007. |
we measured proenkephalin (pek) mrna levels in the anterior and medial aspects of the caudate-putamen (cpu) and in the nucleus accumbens (nac) of the rat by in situ hybridization histochemistry after chronic treatment for 21 days with typical (haloperidol and prolixin) and atypical (molindone, thioridazine, and clozapine) neuroleptics. |
1990-06-18 |
2023-08-11 |
rat |
| S R Wachtel, X T Hu, M P Galloway, F J Whit. D1 dopamine receptor stimulation enables the postsynaptic, but not autoreceptor, effects of D2 dopamine agonists in nigrostriatal and mesoaccumbens dopamine systems. Synapse (New York, N.Y.). vol 4. issue 4. 1990-01-31. PMID:2532422. |
possible functional interactions between d1 and d2 dopamine (da) receptors were examined using extracellular single-cell recording with microiontophoretic application of selective d1 and d2 receptor agonists both postsynaptically, in the rat nucleus accumbens (nac) and caudate-putamen (cpu), and presynaptically, at impulse-regulating somatodendritic da autoreceptors in the ventral tegmental area (a10) and substantia nigra pars compacta (a9). |
1990-01-31 |
2023-08-11 |
rat |
| M Jeziorski, F J Whit. Dopamine agonists at repeated "autoreceptor-selective" doses: effects upon the sensitivity of A10 dopamine autoreceptors. Synapse (New York, N.Y.). vol 4. issue 4. 1990-01-31. PMID:2603146. |
however, ibotenic acid lesions of postsynaptic cells in the nucleus accumbens (nac) prior to initiation of apo treatment (2 x 50 micrograms/kg/day) did not alter the response of a10 cells to systemic quin, contradicting the possibility that the feedback projection from the nac to the vta was compensating for autoreceptor down-regulation during systemic challenge with quin. |
1990-01-31 |
2023-08-11 |
rat |
| D J Henry, M A Greene, F J Whit. Electrophysiological effects of cocaine in the mesoaccumbens dopamine system: repeated administration. The Journal of pharmacology and experimental therapeutics. vol 251. issue 3. 1990-01-30. PMID:2557418. |
behavioral evidence indicates that the potent rewarding effects of cocaine are mediated, in part, by the mesoaccumbens dopamine (da) system projecting from a10 da cells in the ventral tegmental area (vta) to the nucleus accumbens (nac). |
1990-01-30 |
2023-08-11 |
rat |
| N R Swerdlow, G F Koo. Norepinephrine stimulates behavioral activation in rats following depletion of nucleus accumbens dopamine. Pharmacology, biochemistry, and behavior. vol 33. issue 3. 1989-12-29. PMID:2511575. |
other rats were pretreated with desmethylimipramine (dmi) and then received 6ohda infusions into the nucleus accumbens (nac) to selectively deplete dopamine (da) from this region. |
1989-12-29 |
2023-08-11 |
rat |
| D Nakahara, N Ozaki, V Kapoor, T Nagats. The effect of uptake inhibition on dopamine release from the nucleus accumbens of rats during self- or forced stimulation of the medial forebrain bundle: a microdialysis study. Neuroscience letters. vol 104. issue 1-2. 1989-12-20. PMID:2812526. |
changes in dopamine (da) release were measured in microdialysis samples taken from the nucleus accumbens (nac) of rats pretreated with the da uptake inhibitor, nomifensine (1 mg/kg, i.p.) |
1989-12-20 |
2023-08-11 |
rat |
| M W Jones, I C Kilpatrick, O T Phillipso. Regulation of dopamine function in the nucleus accumbens of the rat by the thalamic paraventricular nucleus and adjacent midline nuclei. Experimental brain research. vol 76. issue 3. 1989-10-30. PMID:2676574. |
the effects of unilateral treatments applied to non-dopamine containing output neurones of the thalamic paraventricular nucleus and adjacent midline nuclei (pv-mlt) were observed on dopamine (da) utilisation of the nucleus accumbens (nac). |
1989-10-30 |
2023-08-11 |
rat |
| D Nakahara, N Ozaki, Y Miura, H Miura, T Nagats. Increased dopamine and serotonin metabolism in rat nucleus accumbens produced by intracranial self-stimulation of medial forebrain bundle as measured by in vivo microdialysis. Brain research. vol 495. issue 1. 1989-10-19. PMID:2476201. |
in the present study, we have used a newly developed microdialysis system to perfuse the nucleus accumbens (nac) of conscious rats during spontaneous intracranial self-stimulation of the medial forebrain bundle (mfb). |
1989-10-19 |
2023-08-11 |
rat |
| L Pulvirenti, N R Swerdlow, G F Koo. Microinjection of a glutamate antagonist into the nucleus accumbens reduces psychostimulant locomotion in rats. Neuroscience letters. vol 103. issue 2. 1989-10-12. PMID:2771183. |
in order to study a possible modulatory effect of glutamatergic afferents to the nucleus accumbens (nac) on psychostimulant-induced locomotion, l-glutamic acid diethyl ester (gdee), a glutamate antagonist, was injected in the nac of rats acutely treated with cocaine, amphetamine or caffeine. |
1989-10-12 |
2023-08-11 |
rat |
| L Hernandez, B G Hoebe. Feeding and hypothalamic stimulation increase dopamine turnover in the accumbens. Physiology & behavior. vol 44. issue 4-5. 1989-05-05. PMID:3237847. |
first, microdialysis was performed in the nucleus accumbens (nac) at 20 min intervals during free feeding in rats at 80% of normal body weight. |
1989-05-05 |
2023-08-11 |
rat |
| X T Hu, R Y Wan. Comparison of effects of D-1 and D-2 dopamine receptor agonists on neurons in the rat caudate putamen: an electrophysiological study. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 8. issue 11. 1988-12-22. PMID:2972814. |
a comparison of these results with our previous results obtained from the nucleus accumbens (nac) indicates that nac cells are more responsive to da d-2 agonist, whereas cpu cells are more sensitive to d-1 agonist. |
1988-12-22 |
2023-08-11 |
rat |