| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Zhang, M L Ruehr, R V Dorma. Arachidonic acid and oleoylacetylglycerol induce a synergistic facilitation of Ca(2+)-dependent glutamate release from hippocampal mossy fiber nerve endings. Journal of neurochemistry. vol 66. issue 1. 1996-01-24. PMID:8522951. |
arachidonic acid and oleoylacetylglycerol enhance depolarization-evoked glutamate release from hippocampal mossy fiber nerve endings. |
1996-01-24 |
2023-08-12 |
Not clear |
| D K Selig, H K Lee, M F Bear, R C Malenk. Reexamination of the effects of MCPG on hippocampal LTP, LTD, and depotentiation. Journal of neurophysiology. vol 74. issue 3. 1996-01-18. PMID:7500133. |
we examined the effects of the metabotropic glutamate receptor (mglur) antagonist alpha-methyl-4-carboxyphenylglycine (mcpg) on the induction of long-term potentiation (ltp) long-term depression (ltd), and depotentiation in ca1 hippocampal neurons using extracellular recording techniques. |
1996-01-18 |
2023-08-12 |
Not clear |
| M Sciancalepore, F Stratta, N D Fisher, E Cherubin. Activation of metabotropic glutamate receptors increase the frequency of spontaneous GABAergic currents through protein kinase A in neonatal rat hippocampal neurons. Journal of neurophysiology. vol 74. issue 3. 1996-01-18. PMID:7500137. |
activation of metabotropic glutamate receptors increase the frequency of spontaneous gabaergic currents through protein kinase a in neonatal rat hippocampal neurons. |
1996-01-18 |
2023-08-12 |
rat |
| M Sciancalepore, F Stratta, N D Fisher, E Cherubin. Activation of metabotropic glutamate receptors increase the frequency of spontaneous GABAergic currents through protein kinase A in neonatal rat hippocampal neurons. Journal of neurophysiology. vol 74. issue 3. 1996-01-18. PMID:7500137. |
the tight-seal whole cell recording technique was used to study the effects of the metabotropic glutamate receptor (mglur) agonist, trans-1-aminocyclopentane-1,3-dicarboxylic acid (t-acpd) on spontaneous gamma-aminobutyric acid (gaba)-mediated synaptic currents in neonatal rat ca1 hippocampal neurons in slices obtained from postnatal (p) days p6-p12. |
1996-01-18 |
2023-08-12 |
rat |
| N Belluardo, G Mudò, P Dell'Albani, X H Jiang, D F Condorell. NMDA receptor-dependent and -independent immediate early gene expression induced by focal mechanical brain injury. Neurochemistry international. vol 26. issue 5. 1996-01-11. PMID:7492942. |
the zif/268 induction in the hippocampal layers is not blocked even if the intracerebroventricular administration of a non-nmda glutamate receptor antagonist is associated to the systemic pretreatment with ketamine. |
1996-01-11 |
2023-08-12 |
rat |
| A Schurr, R S Payne, B M Rigo. Protection by MK-801 against hypoxia-, excitotoxin-, and depolarization-induced neuronal damage in vitro. Neurochemistry international. vol 26. issue 5. 1996-01-11. PMID:7492949. |
considering (1) the ability of mk-801 to antagonize hypoxic neuronal damage in the absence or the presence of nmda, kainate or ampa; (2) the antihypoxic effect of mk-801 in the presence of apv + 7-chlorokynurenate, a pairing that supposedly blocks mk-801 binding to the nmda receptor; (3) the ability of mk-801 to protect hippocampal slices against brain damage induced by depolarization + excitotoxin (50 mm kcl + mm glutamate for 60 min); and (4) the ability of diltiazem, an l-type calcium channel blocker, to protect hippocampal slices against hypoxic neuronal damage, we conclude that the mode of action of mk-801 cannot be explained by its nmda receptor antagonistic properties alone. |
1996-01-11 |
2023-08-12 |
rat |
| T Hama, A Ogura, A Omori, M Murayama, M Kubota, M Sekiguchi, M Ishiguro, M Maruyama, H Hatanaka, K Sat. A 13-Mer peptide of a brain injury-derived protein supports neuronal survival and rescues neurons from injury caused by glutamate. The Journal of biological chemistry. vol 270. issue 49. 1996-01-11. PMID:7493927. |
this 13-mer peptide promoted survival of septal cholinergic and mesencephalic dopaminergic neurons in culture and rescued hippocampal neurons from injury caused by glutamate in culture. |
1996-01-11 |
2023-08-12 |
rat |
| S S Deshpande, C D Smith, M G Filber. Assessment of primary neuronal culture as a model for soman-induced neurotoxicity and effectiveness of memantine as a neuroprotective drug. Archives of toxicology. vol 69. issue 6. 1996-01-11. PMID:7495376. |
the link between soman toxicity, glutamate hyperactivity and neuronal death in the central nervous system was investigated in primary dissociated cell cultures from rat hippocampus and cerebral neocortex. |
1996-01-11 |
2023-08-12 |
rat |
| S S Deshpande, C D Smith, M G Filber. Assessment of primary neuronal culture as a model for soman-induced neurotoxicity and effectiveness of memantine as a neuroprotective drug. Archives of toxicology. vol 69. issue 6. 1996-01-11. PMID:7495376. |
exposure of cortical or hippocampal neurons to glutamate for 30 min produced neuronal death in almost 80% of the cells examined at 24 h. hippocampal neurons exposed to soman for 15-120 min at 0.1 microm concentration caused almost complete inhibition (> or = 90%) of acetylcholinesterase but failed to show any evidence of effects on cell viability, indicating a lack of direct cytotoxicity by this agent. |
1996-01-11 |
2023-08-12 |
rat |
| S S Deshpande, C D Smith, M G Filber. Assessment of primary neuronal culture as a model for soman-induced neurotoxicity and effectiveness of memantine as a neuroprotective drug. Archives of toxicology. vol 69. issue 6. 1996-01-11. PMID:7495376. |
acetylcholine (ach, 0.1 mm), alone or in combination with soman, did not potentiate glutamate toxicity in hippocampal neurons. |
1996-01-11 |
2023-08-12 |
rat |
| S S Deshpande, C D Smith, M G Filber. Assessment of primary neuronal culture as a model for soman-induced neurotoxicity and effectiveness of memantine as a neuroprotective drug. Archives of toxicology. vol 69. issue 6. 1996-01-11. PMID:7495376. |
memantine, a drug used for the therapy of parkinson's disease, spasticity and other brain disorders, significantly protected hippocampal and cortical neurons in culture against glutamate and n-methyl-d-aspartate (nmda) excitotoxicity. |
1996-01-11 |
2023-08-12 |
rat |
| J M Dubinsky, B S Kristal, M Elizondo-Fournie. An obligate role for oxygen in the early stages of glutamate-induced, delayed neuronal death. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 11. 1995-12-26. PMID:7472462. |
therefore, we assessed neuronal survival and intracellular calcium concentrations ([ca2+]i) in neonatal hippocampal cultures in response to glutamate in the presence and absence of oxygen. |
1995-12-26 |
2023-08-12 |
Not clear |
| D W Newell, A Barth, V Papermaster, A T Malou. Glutamate and non-glutamate receptor mediated toxicity caused by oxygen and glucose deprivation in organotypic hippocampal cultures. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 11. 1995-12-26. PMID:7472521. |
glutamate and non-glutamate receptor mediated toxicity caused by oxygen and glucose deprivation in organotypic hippocampal cultures. |
1995-12-26 |
2023-08-12 |
Not clear |
| D W Newell, A Barth, V Papermaster, A T Malou. Glutamate and non-glutamate receptor mediated toxicity caused by oxygen and glucose deprivation in organotypic hippocampal cultures. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 11. 1995-12-26. PMID:7472521. |
the presence of glucose during complete oxygen deprivation appears to prevent glutamate receptor blockade from reducing neuronal injury in organotypic hippocampal cultures. |
1995-12-26 |
2023-08-12 |
Not clear |
| H J Kang, E M Schuma. Neurotrophin-induced modulation of synaptic transmission in the adult hippocampus. Journal of physiology, Paris. vol 89. issue 1. 1995-12-22. PMID:7581294. |
moreover, the level of expression of the neurotrophins in the hippocampus can be regulated by a variety of neuronal inputs, such as experimentally-induced seizures, injection of glutamate receptor agonists, and ltp-inducing stimulation. |
1995-12-22 |
2023-08-12 |
rat |
| K N Kumar, K K Babcock, P S Johnson, X Chen, M Ahmad, E K Michaeli. Cloning of the cDNA for a brain glycine-, glutamate- and thienylcyclohexylpiperidine-binding protein. Biochemical and biophysical research communications. vol 216. issue 1. 1995-12-21. PMID:7488117. |
the ab's were used to immunopurify from brain synaptic membranes a 60-kda glycine (gly), glutamate (glu) and thienylcyclohexylpiperidine (tcp)-binding protein and to screen a rat hippocampal cdna expression library. |
1995-12-21 |
2023-08-12 |
rat |
| C Behl, M Widmann, T Trapp, F Holsboe. 17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro. Biochemical and biophysical research communications. vol 216. issue 2. 1995-12-21. PMID:7488136. |
the potential antioxidant activity of 17-beta estradiol and other steroid hormones in neuronal cells was investigated by studying oxidative stress-induced cell death caused by the neurotoxins amyloid beta protein, hydrogen peroxide and glutamate in the clonal mouse hippocampal cell line ht22. |
1995-12-21 |
2023-08-12 |
mouse |
| U Strasser, G Fische. Protection from neuronal damage induced by combined oxygen and glucose deprivation in organotypic hippocampal cultures by glutamate receptor antagonists. Brain research. vol 687. issue 1-2. 1995-12-14. PMID:7583301. |
protection from neuronal damage induced by combined oxygen and glucose deprivation in organotypic hippocampal cultures by glutamate receptor antagonists. |
1995-12-14 |
2023-08-12 |
Not clear |
| U Strasser, G Fische. Protection from neuronal damage induced by combined oxygen and glucose deprivation in organotypic hippocampal cultures by glutamate receptor antagonists. Brain research. vol 687. issue 1-2. 1995-12-14. PMID:7583301. |
the involvement of different glutamate receptors in individual hippocampal subfields (ca1, ca3 and dentate gyrus) was studied using antagonists of nmda (dizocilpine) and ampa/kainate receptors (cnqx and gyki 52466). |
1995-12-14 |
2023-08-12 |
Not clear |
| Y Yamazaki, Y Kiuchi, M Inagaki, M Matsumoto, C Yokomizo, N Nakachi, T Uchikawa, K Oguch. [Increase in extracellular levels of serotonin and amino acids in the rat brain following cyanide-induced energy failure]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 15. issue 4. 1995-12-14. PMID:7584727. |
ringer's solution containing 2 mm sodium cyanide (nacn) was perfused into the hippocampus and striatum for 60 min via a microdialysis probe, and changes in serotonin (5-ht) and amino acids (glutamate, aspartate and taurine) levels in dialysates were investigated. |
1995-12-14 |
2023-08-12 |
rat |