| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Kim, K S Jun, S B Lee, N G Kang, D S Min, Y H Kim, S H Ryu, P G Suh, H S Shi. Phospholipase C isozymes selectively couple to specific neurotransmitter receptors. Nature. vol 389. issue 6648. 1997-09-30. PMID:9305844. |
we determined the molecular basis of these phenotypes and show that plc-beta1 is involved in signal transduction in the cerebral cortex and hippocampus by coupling predominantly to the muscarinic acetylcholine receptor, whereas plc-beta4 works through the metabotropic glutamate receptor in the cerebellum, illustrating how plc-beta isoenzymes are used to generate different functions in the brain. |
1997-09-30 |
2023-08-12 |
mouse |
| L Massieu, R Tapi. Glutamate uptake impairment and neuronal damage in young and aged rats in vivo. Journal of neurochemistry. vol 69. issue 3. 1997-09-25. PMID:9282938. |
drugs were administered by microdialysis and glutamate concentration was determined by hplc in the striatum and the hippocampus of 3-month-old and 22-24-month-old rats. |
1997-09-25 |
2023-08-12 |
rat |
| L Massieu, R Tapi. Glutamate uptake impairment and neuronal damage in young and aged rats in vivo. Journal of neurochemistry. vol 69. issue 3. 1997-09-25. PMID:9282938. |
in contrast, dihydrokainate had a poor effect on glutamate levels, but induced clear neuronal damage in the striatum and the hippocampus in both groups of rats. |
1997-09-25 |
2023-08-12 |
rat |
| S E Tan, S S Che. The activation of calcium/calmodulin-dependent protein kinase II after glutamate or potassium stimulation in hippocampal slices. Brain research bulletin. vol 43. issue 3. 1997-09-16. PMID:9227836. |
the activation of calcium/calmodulin-dependent protein kinase ii after glutamate or potassium stimulation in hippocampal slices. |
1997-09-16 |
2023-08-12 |
rat |
| D M O'Leary, J J O'Conno. Potentiation of synaptic transmission in the rat dentate gyrus in vitro by (S)-3,5-dihydroxyphenylglycine ((S)-DHPG). Neuroscience letters. vol 229. issue 1. 1997-09-12. PMID:9224794. |
the direct activation of metabotropic glutamate receptors (mglurs) by 1s,3r-aminocyclopentane dicarboxylate (1s,3r-acpd), has previously been shown to induce a relatively fast (maximum at 10 min) and slow (90 min) onset long-term potentiation (ltp) of synaptic transmission in the hippocampus. |
1997-09-12 |
2023-08-12 |
rat |
| R S Bitner, G K Yim, G E Iso. 2-Iminothiazolidine-4-carboxylic acid produces hippocampal CA1 lesions independent of seizure excitation and glutamate receptor activation. Neurotoxicology. vol 18. issue 1. 1997-09-09. PMID:9216001. |
to produce hippocampal lesions sensitive to glutamate antagonists was compared in mice. |
1997-09-09 |
2023-08-12 |
mouse |
| R S Bitner, G K Yim, G E Iso. 2-Iminothiazolidine-4-carboxylic acid produces hippocampal CA1 lesions independent of seizure excitation and glutamate receptor activation. Neurotoxicology. vol 18. issue 1. 1997-09-09. PMID:9216001. |
glutamate (3.2 mumol) or proline (10 mumol) also produced hippocampal damage; glutamate damage was primarily to the ca1 subfield, whereas proline damaged neurons throughout the entire hippocampal formation. |
1997-09-09 |
2023-08-12 |
mouse |
| R S Bitner, G K Yim, G E Iso. 2-Iminothiazolidine-4-carboxylic acid produces hippocampal CA1 lesions independent of seizure excitation and glutamate receptor activation. Neurotoxicology. vol 18. issue 1. 1997-09-09. PMID:9216001. |
in contrast, mk-801 significantly reduced the frequency of mice displaying glutamate hippocampal lesions, but failed to block seizures produced by glutamate. |
1997-09-09 |
2023-08-12 |
mouse |
| R S Bitner, G K Yim, G E Iso. 2-Iminothiazolidine-4-carboxylic acid produces hippocampal CA1 lesions independent of seizure excitation and glutamate receptor activation. Neurotoxicology. vol 18. issue 1. 1997-09-09. PMID:9216001. |
finally, pretreatment with the mixed metabotropic glutamate receptor (mglur)1/mglur2 antagonist-agonist (s)-4-carboxy-3-hydroxyphenylglycine (chpg) prevented hippocampal damage produced by the mglur1 agonist (rs)-3,5-dihydroxyphenylglycine (dhpg), but did not protect against 2-ica hippocampal lesions. |
1997-09-09 |
2023-08-12 |
mouse |
| A Pittaluga, A Bonfanti, M Raiter. Differential desensitization of ionotropic non-NMDA receptors having distinct neuronal location and function. Naunyn-Schmiedeberg's archives of pharmacology. vol 356. issue 1. 1997-09-05. PMID:9228187. |
the release of tritium from rat hippocampal synaptosomes prelabeled with [3h]noradrenaline ([3h]na) or [3h]5-hydroxytryptamine ([3h]5-ht) and from rat neocortex synaptosomes prelabeled with [3h]choline and the release of endogenous gaba and glutamate from rat neocortex synaptosomes were monitored during superfusion with media containing varying concentrations of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) or kainic acid. |
1997-09-05 |
2023-08-12 |
rat |
| S M Cohen, J V Nadle. Sodium-dependent proline and glutamate uptake by hippocampal synaptosomes during postnatal development. Brain research. Developmental brain research. vol 100. issue 2. 1997-09-03. PMID:9205813. |
sodium-dependent proline and glutamate uptake by hippocampal synaptosomes during postnatal development. |
1997-09-03 |
2023-08-12 |
Not clear |
| S M Cohen, J V Nadle. Sodium-dependent proline and glutamate uptake by hippocampal synaptosomes during postnatal development. Brain research. Developmental brain research. vol 100. issue 2. 1997-09-03. PMID:9205813. |
na(+)-dependent uptake of proline and glutamate by hippocampal synaptosomes was studied during postnatal development. |
1997-09-03 |
2023-08-12 |
Not clear |
| S M Cohen, J V Nadle. Sodium-dependent proline and glutamate uptake by hippocampal synaptosomes during postnatal development. Brain research. Developmental brain research. vol 100. issue 2. 1997-09-03. PMID:9205813. |
at all ages from 9 days to adulthood, hippocampal synaptosomes transported proline by both a high-affinity and a low-affinity process, whereas glutamate was always transported predominantly by a high-affinity process. |
1997-09-03 |
2023-08-12 |
Not clear |
| S M Cohen, J V Nadle. Sodium-dependent proline and glutamate uptake by hippocampal synaptosomes during postnatal development. Brain research. Developmental brain research. vol 100. issue 2. 1997-09-03. PMID:9205813. |
although high-affinity transporters for proline and glutamate are expressed by nearly the same hippocampal pathways, they are differentially regulated during postnatal development. |
1997-09-03 |
2023-08-12 |
Not clear |
| R H Porter, S L Eastwood, P J Harriso. Distribution of kainate receptor subunit mRNAs in human hippocampus, neocortex and cerebellum, and bilateral reduction of hippocampal GluR6 and KA2 transcripts in schizophrenia. Brain research. vol 751. issue 2. 1997-09-02. PMID:9099808. |
in conjunction with earlier findings of reduced hippocampal glur1 and glur2 expression and a loss of [3h]ka binding sites, these data show that schizophrenia is associated with impaired expression of both ampa- and ka-preferring ionotropic glutamate receptors. |
1997-09-02 |
2023-08-12 |
human |
| Z Liu, C E Stafstrom, M R Sarkisian, Y Yang, A Hori, P Tandon, G L Holme. Seizure-induced glutamate release in mature and immature animals: an in vivo microdialysis study. Neuroreport. vol 8. issue 8. 1997-08-29. PMID:9223095. |
a glutamate biosensor was used to measure extracellular glutamate concentrations in the hippocampus of mature and immature animals. |
1997-08-29 |
2023-08-12 |
Not clear |
| F Robert, L Parisi, L Bert, B Renaud, L Stoppin. Microdialysis monitoring of extracellular glutamate combined with the simultaneous recording of evoked field potentials in hippocampal organotypic slice cultures. Journal of neuroscience methods. vol 74. issue 1. 1997-08-27. PMID:9210576. |
microdialysis monitoring of extracellular glutamate combined with the simultaneous recording of evoked field potentials in hippocampal organotypic slice cultures. |
1997-08-27 |
2023-08-12 |
Not clear |
| F Robert, L Parisi, L Bert, B Renaud, L Stoppin. Microdialysis monitoring of extracellular glutamate combined with the simultaneous recording of evoked field potentials in hippocampal organotypic slice cultures. Journal of neuroscience methods. vol 74. issue 1. 1997-08-27. PMID:9210576. |
glutamate (glu) concentrations were monitored in 0.5 or 2 min microdialysis samples, while evoked field potentials responses (evfpr) in the ca1 region of the hippocampus (stimulation in the ca3 area) were simultaneously recorded using a multi-electrodes array (physiocard). |
1997-08-27 |
2023-08-12 |
Not clear |
| P C Suen, K Wu, E S Levine, H T Mount, J L Xu, S Y Lin, I B Blac. Brain-derived neurotrophic factor rapidly enhances phosphorylation of the postsynaptic N-methyl-D-aspartate receptor subunit 1. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 15. 1997-08-27. PMID:9223337. |
activation of trkb also modulates hippocampal long-term potentiation, in which postsynaptic n-methyl-d-aspartate glutamate receptors play a key role. |
1997-08-27 |
2023-08-12 |
Not clear |
| P E Castillo, R Janz, T C Südhof, T Tzounopoulos, R C Malenka, R A Nicol. Rab3A is essential for mossy fibre long-term potentiation in the hippocampus. Nature. vol 388. issue 6642. 1997-08-27. PMID:9252190. |
ltp at most synapses involves the activation of the nmda (n-methyl-d-aspartate) subtype of glutamate receptor, but ltp at hippocampal mossy fibre synapses is independent of nmda receptors and has a component that is induced and expressed presynaptically. |
1997-08-27 |
2023-08-12 |
mouse |