| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Flott-Rahmel, M Schürmann, P Schluff, R Fingerhut, U Musshoff, B Fowler, K Ullric. Homocysteic and homocysteine sulphinic acid exhibit excitotoxicity in organotypic cultures from rat brain. European journal of pediatrics. vol 157 Suppl 2. 1998-07-14. PMID:9587037. |
the excitotoxic action of homocysteine and related sulphur-containing metabolites was investigated in organotpyic cultures derived from rat brain cortex and hippocampus by inhibition experiments using antagonists selective for different glutamate receptor subtypes. |
1998-07-14 |
2023-08-12 |
rat |
| S Tan, Y Sagara, Y Liu, P Maher, D Schuber. The regulation of reactive oxygen species production during programmed cell death. The Journal of cell biology. vol 141. issue 6. 1998-07-13. PMID:9628898. |
the role of ros in cell death caused by oxidative glutamate toxicity was studied in an immortalized mouse hippocampal cell line (ht22). |
1998-07-13 |
2023-08-12 |
mouse |
| D V Lissin, S N Gomperts, R C Carroll, C W Christine, D Kalman, M Kitamura, S Hardy, R A Nicoll, R C Malenka, M von Zastro. Activity differentially regulates the surface expression of synaptic AMPA and NMDA glutamate receptors. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 12. 1998-07-09. PMID:9618545. |
to address whether neuronal activity may differentially regulate the surface expression at synapses of two specific subtypes of ionotropic glutamate receptors we epitope-tagged an ampa (alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid) receptor subunit (glur1) and an nmda (n-methyl-d-aspartate) receptor subunit (nr1) on their extracellular termini and expressed these proteins in cultured hippocampal neurons using recombinant adenoviruses. |
1998-07-09 |
2023-08-12 |
Not clear |
| E M Aronica, J A Gorter, S Grooms, J A Kessler, M V Bennett, R S Zukin, D M Rosenbau. Aurintricarboxylic acid prevents GLUR2 mRNA down-regulation and delayed neurodegeneration in hippocampal CA1 neurons of gerbil after global ischemia. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 12. 1998-07-09. PMID:9618548. |
in this study, we examined the effects of ata on expression of mrnas encoding glutamate receptor subunits in gerbil hippocampus after global ischemia. |
1998-07-09 |
2023-08-12 |
rat |
| S Tan, M Wood, P Mahe. Oxidative stress induces a form of programmed cell death with characteristics of both apoptosis and necrosis in neuronal cells. Journal of neurochemistry. vol 71. issue 1. 1998-07-09. PMID:9648855. |
to study the effects of oxidative stress on neuronal cells, we have used an immortalized mouse hippocampal cell line (ht-22) that is particularly sensitive to glutamate. |
1998-07-09 |
2023-08-12 |
mouse |
| S Mennerick, R P Dhond, A Benz, W Xu, J D Rothstein, N C Danbolt, K E Isenberg, C F Zorumsk. Neuronal expression of the glutamate transporter GLT-1 in hippocampal microcultures. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 12. 1998-07-08. PMID:9614226. |
neuronal expression of the glutamate transporter glt-1 in hippocampal microcultures. |
1998-07-08 |
2023-08-12 |
rat |
| S Mennerick, R P Dhond, A Benz, W Xu, J D Rothstein, N C Danbolt, K E Isenberg, C F Zorumsk. Neuronal expression of the glutamate transporter GLT-1 in hippocampal microcultures. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 12. 1998-07-08. PMID:9614226. |
to address the question of the relative contributions of glial and neuronal glutamate transport in the vertebrate cns, we studied the distribution of forebrain glutamate transporters in rat hippocampal microcultures, a preparation in which physiological functions of glutamate transporters have been well characterized. |
1998-07-08 |
2023-08-12 |
rat |
| A V Sergutin. [Comparative cytochemical study of the central nervous system in Wistar and August rats in dopamine system hyperfunction]. Morfologiia (Saint Petersburg, Russia). vol 113. issue 1. 1998-07-02. PMID:9606663. |
in august rats l-dopa administration caused aminopeptidase activity increase in sensomotor cortex layer 3 and nucleus accumbens, glutamate dehydrogenase activity growth in nucleus accumbens as well as the elevation of monoaminoxidase (mao) activity in nucleus caudatus and nucleus accumbens (serotonin as substrate) and in nucleus caudatus and hippocampus (tryptamine as substrate), while acetyl cholinesterase activity did not change at all. |
1998-07-02 |
2023-08-12 |
rat |
| M Li. [Studies on the anti-aging and nootropic effects of ginsenoside Rg1 and its mechanisms of actions]. Sheng li ke xue jin zhan [Progress in physiology]. vol 27. issue 2. 1998-06-25. PMID:9592237. |
in the present studies, rg1 was found to selectively enhance the deteriorated immune function in aged animals, ameliorate age-related alterations in both behavior and motor response, promote hippocampal neuronal function of aged rats, and provide partial protection against the excitotoxic effect of glutamate. |
1998-06-25 |
2023-08-12 |
rat |
| O Miyamoto, J Minami, T Toyoshima, T Nakamura, T Masada, S Nagao, T Negi, T Itano, A Okab. Neurotoxicity of Clostridium perfringens epsilon-toxin for the rat hippocampus via the glutamatergic system. Infection and immunity. vol 66. issue 6. 1998-06-25. PMID:9596708. |
prior injection of either a glutamate release inhibitor or a glutamate receptor antagonist protected the hippocampus from the neuronal damage caused by epsilon-toxin. |
1998-06-25 |
2023-08-12 |
rat |
| H Neumann, T Misgeld, K Matsumuro, H Wekerl. Neurotrophins inhibit major histocompatibility class II inducibility of microglia: involvement of the p75 neurotrophin receptor. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 10. 1998-06-19. PMID:9576961. |
interferon-gamma (ifn-gamma)-dependent mhc class ii inducibility in microglia cells was very low, but strongly increased in the hippocampal slices after the blockade of neuronal activity by neurotoxins [tetrodotoxin (ttx), omega-conotoxin] or glutamate antagonists. |
1998-06-19 |
2023-08-12 |
rat |
| P E Bickler, B M Hanse. Hypoxia-tolerant neonatal CA1 neurons: relationship of survival to evoked glutamate release and glutamate receptor-mediated calcium changes in hippocampal slices. Brain research. Developmental brain research. vol 106. issue 1-2. 1998-06-18. PMID:9554954. |
hypoxia-tolerant neonatal ca1 neurons: relationship of survival to evoked glutamate release and glutamate receptor-mediated calcium changes in hippocampal slices. |
1998-06-18 |
2023-08-12 |
rat |
| P E Bickler, B M Hanse. Hypoxia-tolerant neonatal CA1 neurons: relationship of survival to evoked glutamate release and glutamate receptor-mediated calcium changes in hippocampal slices. Brain research. Developmental brain research. vol 106. issue 1-2. 1998-06-18. PMID:9554954. |
to investigate how developmental changes in glutamate receptor-mediated neurotoxicity contribute to this difference, we measured hypoxia-evoked glutamate release, glutamate receptor contribution to hypoxia-evoked intracellular calcium changes, and survival of hypoxia-/ischemia-sensitive ca1 neurons in rat hippocampus. |
1998-06-18 |
2023-08-12 |
rat |
| P E Bickler, B M Hanse. Hypoxia-tolerant neonatal CA1 neurons: relationship of survival to evoked glutamate release and glutamate receptor-mediated calcium changes in hippocampal slices. Brain research. Developmental brain research. vol 106. issue 1-2. 1998-06-18. PMID:9554954. |
glutamate release was measured by a fluorescence assay, calcium changes in ca1 neurons with fura-2, and cell viability using nissl and fluorescence staining with calcein-am/ethidium homodimer, all in 300-micron thick hippocampal slices from 3-30 post-natal day (pnd) rats. |
1998-06-18 |
2023-08-12 |
rat |
| K Fukunaga, E Miyamot. Role of MAP kinase in neurons. Molecular neurobiology. vol 16. issue 1. 1998-06-16. PMID:9554703. |
in cultured hippocampal neurons, simulation of glutamate receptors can activate erk signaling, for which elevation of intracellular ca2+ is required. |
1998-06-16 |
2023-08-12 |
Not clear |
| R Nouranifar, R D Blitzer, T Wong, E Landa. Metabotropic glutamate receptors limit adenylyl cyclase-mediated effects in rat hippocampus via protein kinase C. Neuroscience letters. vol 244. issue 2. 1998-06-16. PMID:9572595. |
metabotropic glutamate receptors limit adenylyl cyclase-mediated effects in rat hippocampus via protein kinase c. glutamate receptors of the metabotropic type (mglurs) activate protein kinase c in hippocampus, but few physiological functions of this pathway are known. |
1998-06-16 |
2023-08-12 |
rat |
| K Yamad. [Role of nitric oxide in learning and memory processes]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 111. issue 2. 1998-06-15. PMID:9558647. |
no acts as a retrograde messenger in the hippocampal ltp to enhance glutamate release from presynaptic nerve terminal, in which cyclic gmp may be involved. |
1998-06-15 |
2023-08-12 |
Not clear |
| E Adamec, M L Beermann, R A Nixo. Calpain I activation in rat hippocampal neurons in culture is NMDA receptor selective and not essential for excitotoxic cell death. Brain research. Molecular brain research. vol 54. issue 1. 1998-06-10. PMID:9526039. |
administration of glutamate (100 microm) to primary cultures of rat hippocampal neurons for 1 h led to calpain i activation as determined by monitoring the extent of spectrin breakdown with the antibodies designed to specifically recognize the calpain i-mediated spectrin breakdown products. |
1998-06-10 |
2023-08-12 |
rat |
| A Regner, G Ramirez, A Belló-Klein, D Souz. Effects of guanine nucleotides on glutamate-induced chemiluminescence in rat hippocampal slices submitted to hypoxia. Neurochemical research. vol 23. issue 4. 1998-06-09. PMID:9566586. |
glutamate significantly increased levels of spontaneous chemiluminescence (cl) in rat hippocampal slices incubated under hypoxic conditions. |
1998-06-09 |
2023-08-12 |
rat |
| P Saransaari, S S Oj. Release of endogenous glutamate, aspartate, GABA, and taurine from hippocampal slices from adult and developing mice under cell-damaging conditions. Neurochemical research. vol 23. issue 4. 1998-06-09. PMID:9566593. |
release of endogenous glutamate, aspartate, gaba, and taurine from hippocampal slices from adult and developing mice under cell-damaging conditions. |
1998-06-09 |
2023-08-12 |
mouse |