| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Liesl Maria Fernandes E Mendonça, Arun Bhimrao Joshi, Anant Bhandarkar, Shamshad Shaikh, Samantha Fernandes, Himanshu Joshi, Shrinivas Josh. Potential anxiolytic therapeutics from Hybanthus enneaspermus (L.) F. Muell. - mitigate anxiety by plausibly modulating the GABA Neurochemistry international. 2024-07-13. PMID:39002759. |
monoamines (serotonin, noradrenaline, dopamine), gamma-aminobutyric acid (gaba), and glutamate were quantified in the different regions of rats' brain (cortex, hippocampus, pons, medulla oblongata, cerebellum). |
2024-07-13 |
2024-07-16 |
rat |
| Xian-Xi Ye, Qiao-Ying Jiang, Meng-Jun Wu, Qing-Huai Ye, Hong Zhen. Transplant of fecal microbiota from healthy young mice relieves cognitive defects in late-stage diabetic mice by reducing metabolic disorders and neuroinflammation. Acta pharmacologica Sinica. 2024-07-11. PMID:38992120. |
fmt also reshaped the metabolic phenotypes in the hippocampus of t1d mice especially for alanine, aspartate and glutamate metabolism. |
2024-07-11 |
2024-07-14 |
mouse |
| Benedikt Zott, Lea Nästle, Christine Grienberger, Felix Unger, Manuel M Knauer, Christian Wolf, Aylin Keskin-Dargin, Anna Feuerbach, Marc Aurel Busche, Arne Skerra, Arthur Konnert. β-amyloid monomer scavenging by an anticalin protein prevents neuronal hyperactivity in mouse models of Alzheimer's Disease. Nature communications. vol 15. issue 1. 2024-07-10. PMID:38987287. |
using in vivo two-photon calcium imaging and sf-iglusnfr-based glutamate imaging in hippocampal slices, we demonstrate that an aβ binding anticalin protein (aβ-anticalin) can suppress early neuronal hyperactivity and synaptic glutamate accumulation in the app23xps45 mouse model of β-amyloidosis. |
2024-07-10 |
2024-07-13 |
mouse |
| Donghao Xu, Qingfa Ren, Quanyuan Liu, Miaomiao Liu, He Gong, Yuwei Liu, Zhijie Yin, Zhen Zeng, Shuyuan Xia, Yanyan Zhang, Jie Li, Quansheng Gao, Jing Wang, Xianglin L. Hippocampal Glutamate Levels and Their Correlation With Subregion Volume in School-Aged Children With MRI-Negative Epilepsy: A Preliminary Study. Journal of magnetic resonance imaging : JMRI. 2024-07-06. PMID:38970314. |
hippocampal glutamate levels and their correlation with subregion volume in school-aged children with mri-negative epilepsy: a preliminary study. |
2024-07-06 |
2024-07-12 |
Not clear |
| Ji-Woon Kim, Benjamin Kleinfelter, Ege T Kavalali, Lisa M Monteggi. Distinct synaptic mechanisms drive the behavioral response to acute stress and rapid correction by ketamine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-07-02. PMID:38956176. |
we observed that physostigmine induces acute stress in tandem with long term depression of glutamate release in the hippocampus of mice. |
2024-07-02 |
2024-07-06 |
mouse |
| Tristram Buck, Erbo Dong, Michael McCarthy, Alessandro Guidotti, Monsheel Sodh. Prenatal stress alters transcription of NMDA-type glutamate receptors in the hippocampus. Neuroscience letters. 2024-06-25. PMID:38917870. |
prenatal stress alters transcription of nmda-type glutamate receptors in the hippocampus. |
2024-06-25 |
2024-06-29 |
mouse |
| Fatemeh Rahmati-Dehkordi, Hadi Khanifar, Nazanin Najari, Zeinab Tamtaji, Abdolkarim Talebi Taheri, Michael Aschner, Mehdi Shafiee Ardestani, Hamed Mirzaei, Ehsan Dadgostar, Fatemeh Nabavizadeh, Omid Reza Tamtaj. Therapeutic Potential of Fingolimod on Psychological Symptoms and Cognitive Function in Neuropsychiatric and Neurological Disorders. Neurochemical research. 2024-06-25. PMID:38918332. |
in the hippocampus, fingolimod decreases glutamate levels and increases gaba levels, suggesting a potential role in modulating synaptic transmission and neuronal excitability. |
2024-06-25 |
2024-06-29 |
Not clear |
| Sri-Arun Iamjan, Siriluk Veerasakul, Gavin P Reynolds, Samur Thanoi, Sutisa Nudmamud-Thano. Regional-specific changes in rat brain BDNF in a model of methamphetamine abuse. Neuroscience letters. 2024-06-17. PMID:38885757. |
the hippocampal bdnf increase may reflect an initial increase in a protective factor produced in response to elevated glutamate release resulting in neurodegenerative excitotoxicity. |
2024-06-17 |
2024-06-21 |
rat |
| Woo Suk Roh, Jae Hong Yoo, Shashank M Dravid, Guido Mannaioni, Elizabeth N Krizman, Philip Wahl, Michael B Robinson, Stephen F Traynelis, C Justin Lee, Kyung-Seok Ha. Astrocytic PAR1 and mGluR2/3 control synaptic glutamate time course at hippocampal CA1 synapses. Glia. 2024-06-12. PMID:38864289. |
furthermore, activation of mglur2/3 causes glutamate release through the trek-1 channel in hippocampal astrocytes. |
2024-06-12 |
2024-06-14 |
mouse |
| Woo Suk Roh, Jae Hong Yoo, Shashank M Dravid, Guido Mannaioni, Elizabeth N Krizman, Philip Wahl, Michael B Robinson, Stephen F Traynelis, C Justin Lee, Kyung-Seok Ha. Astrocytic PAR1 and mGluR2/3 control synaptic glutamate time course at hippocampal CA1 synapses. Glia. 2024-06-12. PMID:38864289. |
these data show that astrocytic gpcrs engage in a novel regulatory mechanism to shape the time course of synaptically-released glutamate in excitatory synapses of the hippocampus. |
2024-06-12 |
2024-06-14 |
mouse |
| Tiantian Lu, Xiuling Chen, Qin Zhang, Kun Shang, Xiaogui Yang, Wei Xian. Vitamin D Relieves Epilepsy Symptoms and Neuroinflammation in Juvenile Mice by Activating the mTOR Signaling Pathway via RAF1: Insights from Network Pharmacology and Molecular Docking Studies. Neurochemical research. 2024-06-05. PMID:38837094. |
experimental mouse models of epilepsy were established through intraperitoneal injection of pilocarpine, and in vitro injury models of hippocampal neurons were induced by glutamate (glu) stimulation. |
2024-06-05 |
2024-06-07 |
mouse |
| Chao Lu, Zi-Wei Gao, Shan Xing, Hui-Hui Wang, Yun-Ke Huang, Hang Zhou, Lei W. Rapid Antidepressant-Like Potential of Chaihu Shugan San Depends on Suppressing Glutamate Neurotransmission and Activating Synaptic Proteins in Hippocampus of Female Mice. Chinese journal of integrative medicine. 2024-05-11. PMID:38733455. |
rapid antidepressant-like potential of chaihu shugan san depends on suppressing glutamate neurotransmission and activating synaptic proteins in hippocampus of female mice. |
2024-05-11 |
2024-05-27 |
mouse |
| Karima Schwab, Dilyara Lauer, Mandy Magbagbeolu, Franz Theuring, Anna Gasiorowska, Maciej Zadrozny, Charles R Harrington, Claude M Wischik, Grażyna Niewiadomska, Gernot Riede. Hydromethylthionine rescues synaptic SNARE proteins in a mouse model of tauopathies: interference by cholinesterase inhibitors. Brain research bulletin. 2024-04-27. PMID:38677558. |
interference of cholinesterase inhibition with hmtm was observed also in a tau transgenic mouse model, where rivastigmine reduced the pharmacological activity of hmtm at multiple brain levels including hippocampal acetylcholine release, synaptosomal glutamate release and mitochondrial activity. |
2024-04-27 |
2024-04-30 |
mouse |
| Jun-Meng Wang, Yue-Mei Wang, Yuan-Bing Zhu, Chan Cui, Tong Feng, Qin Huang, Shu-Qing Liu, Qiao-Feng W. Peripheral inflammation triggering central anxiety through the hippocampal glutamate metabolized receptor 1. CNS neuroscience & therapeutics. vol 30. issue 4. 2024-04-27. PMID:38676295. |
peripheral inflammation triggering central anxiety through the hippocampal glutamate metabolized receptor 1. |
2024-04-27 |
2024-04-29 |
mouse |
| Stefan Passlick, Ghanim Ullah, Christian Henneberge. Bidirectional dysregulation of synaptic glutamate signaling after transient metabolic failure. bioRxiv : the preprint server for biology. 2024-04-22. PMID:38645213. |
we modelled acute and transient metabolic failure by using a chemical ischemia protocol and analyzed its effect on glutamatergic synaptic transmission and extracellular glutamate signals by electrophysiology and multiphoton imaging, respectively, in the hippocampus. |
2024-04-22 |
2024-04-24 |
Not clear |
| Zohreh Zare, Sakineh Shafia, Moslem Mohammad. Thyroid hormone deficiency affects anxiety-related behaviors and expression of hippocampal glutamate transporters in male congenital hypothyroid rat offspring. Hormones and behavior. vol 162. 2024-04-18. PMID:38636205. |
thyroid hormone deficiency affects anxiety-related behaviors and expression of hippocampal glutamate transporters in male congenital hypothyroid rat offspring. |
2024-04-18 |
2024-04-21 |
rat |
| Zohreh Zare, Sakineh Shafia, Moslem Mohammad. Thyroid hormone deficiency affects anxiety-related behaviors and expression of hippocampal glutamate transporters in male congenital hypothyroid rat offspring. Hormones and behavior. vol 162. 2024-04-18. PMID:38636205. |
we aimed to examine the consequences of thyroid hormone deficiency on anxiety-related behaviors and protein expression of hippocampal glutamate transporters in congenital hypothyroid male offspring rats. |
2024-04-18 |
2024-04-21 |
rat |
| Zohreh Zare, Sakineh Shafia, Moslem Mohammad. Thyroid hormone deficiency affects anxiety-related behaviors and expression of hippocampal glutamate transporters in male congenital hypothyroid rat offspring. Hormones and behavior. vol 162. 2024-04-18. PMID:38636205. |
thereafter, protein expression of astrocytic (glast and glt-1) and neuronal (eaac1) glutamate transporters were measured in the hippocampus by immunoblotting. |
2024-04-18 |
2024-04-21 |
rat |
| Zohreh Zare, Sakineh Shafia, Moslem Mohammad. Thyroid hormone deficiency affects anxiety-related behaviors and expression of hippocampal glutamate transporters in male congenital hypothyroid rat offspring. Hormones and behavior. vol 162. 2024-04-18. PMID:38636205. |
our findings indicate that thyroid hormone deficiency was associated with alterations in protein expression of glutamate transporters in the hippocampus. |
2024-04-18 |
2024-04-21 |
rat |
| Han-Ying Wang, Hiroshi Takagi, Patrick N Stoney, Anai Echeverria, Bernd Kuhn, Kuei-Sen Hsu, Tomoyuki Takahash. Anoxia-induced hippocampal LTP is regeneratively produced by glutamate and nitric oxide from the neuro-glial-endothelial axis. iScience. vol 27. issue 4. 2024-04-09. PMID:38591010. |
anoxia-induced hippocampal ltp is regeneratively produced by glutamate and nitric oxide from the neuro-glial-endothelial axis. |
2024-04-09 |
2024-04-11 |
mouse |