Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Young H Ju, Angelina Guzzo, Mary W Chiu, Paul Taylor, Michael F Moran, James W Gurd, John F MacDonald, Beverley A Orse. Distinct properties of murine alpha 5 gamma-aminobutyric acid type a receptors revealed by biochemical fractionation and mass spectroscopy. Journal of neuroscience research. vol 87. issue 8. 2009-07-30. PMID:19156871. |
the aim of this study was to modify existing purification and enrichment techniques to isolate alpha 5 gaba(a)rs preferentially from the mouse hippocampus and to identify the alpha 5 subunit by using tandem mass spectroscopy (ms/ms). |
2009-07-30 |
2023-08-12 |
mouse |
Young H Ju, Angelina Guzzo, Mary W Chiu, Paul Taylor, Michael F Moran, James W Gurd, John F MacDonald, Beverley A Orse. Distinct properties of murine alpha 5 gamma-aminobutyric acid type a receptors revealed by biochemical fractionation and mass spectroscopy. Journal of neuroscience research. vol 87. issue 8. 2009-07-30. PMID:19156871. |
mass spectroscopy now offers a method for detecting and characterizing factors that confer the unique detergent solubility and possibly cellular location of alpha 5 gaba(a)rs in hippocampal neurons. |
2009-07-30 |
2023-08-12 |
mouse |
Tara Keck, John A Whit. Glycinergic inhibition in the hippocampus. Reviews in the neurosciences. vol 20. issue 1. 2009-07-29. PMID:19526731. |
while gaba receptors in the hippocampus have been studied in great detail, the role of glycine receptors (glyrs) in the hippocampus is less understood. |
2009-07-29 |
2023-08-12 |
Not clear |
Katrin Frauenknecht, Konstanze Plaschke, Clemens Somme. Transient oligemia is associated with long-term changes in binding densities of cortical inhibitory GABAA receptors in the rat brain. Brain research. vol 1271. 2009-07-28. PMID:19328192. |
since hippocampal excitatory and inhibitory neurotransmitter receptors are crucially involved in spatial memory processes, quantitative in vitro receptor autoradiography was performed using [(3)h]mk-801, [(3)h]ampa, and [(3)h]muscimol for labeling of nmda, ampa, and gaba(a) receptors, respectively. |
2009-07-28 |
2023-08-12 |
rat |
Katrin Frauenknecht, Konstanze Plaschke, Clemens Somme. Transient oligemia is associated with long-term changes in binding densities of cortical inhibitory GABAA receptors in the rat brain. Brain research. vol 1271. 2009-07-28. PMID:19328192. |
after oligemia, hippocampal binding densities of nmda, ampa, and gaba(a) receptors remained unchanged in all subfields investigated. |
2009-07-28 |
2023-08-12 |
rat |
Kristin L Hillman, Saobo Lei, Van A Doze, James E Porte. Alpha-1A adrenergic receptor activation increases inhibitory tone in CA1 hippocampus. Epilepsy research. vol 84. issue 2-3. 2009-07-24. PMID:19201164. |
together, our findings directly link stimulation of the alpha(1a)-ar subtype to release of gaba and somatostatin at the single cell level and suggest that alpha(1a)-ar activation may represent one mechanism by which ne exerts anti-epileptic effects within the hippocampus. |
2009-07-24 |
2023-08-12 |
rat |
Satoshi Yamamura, Tatsuya Hamaguchi, Keiko Ohoyama, Yoshihiro Sugiura, Dai Suzuki, Shinich Kanehara, Masanori Nakagawa, Eishi Motomura, Takuya Matsumoto, Hisashi Tanii, Takashi Shiroyama, Motohiro Okad. Topiramate and zonisamide prevent paradoxical intoxication induced by carbamazepine and phenytoin. Epilepsy research. vol 84. issue 2-3. 2009-07-24. PMID:19268540. |
the dose-dependent effects of aeds on hippocampal extracellular levels of glutamate (glu), gaba, norepinephrine (ne), dopamine (da), and serotonin (5-ht) were determined by microdialysis with high-speed and high-sensitive extreme liquid chromatography. |
2009-07-24 |
2023-08-12 |
rat |
Satoshi Yamamura, Tatsuya Hamaguchi, Keiko Ohoyama, Yoshihiro Sugiura, Dai Suzuki, Shinich Kanehara, Masanori Nakagawa, Eishi Motomura, Takuya Matsumoto, Hisashi Tanii, Takashi Shiroyama, Motohiro Okad. Topiramate and zonisamide prevent paradoxical intoxication induced by carbamazepine and phenytoin. Epilepsy research. vol 84. issue 2-3. 2009-07-24. PMID:19268540. |
therapeutically relevant doses of azm, cbz, tpm, and zns increased hippocampal extracellular levels of gaba, ne, da, and 5-ht, while pht had no effect. |
2009-07-24 |
2023-08-12 |
rat |
Satoshi Kuramoto, Takao Yasuhara, Takashi Agari, Akihiko Kondo, Toshihiro Matsui, Yasuyuki Miyoshi, Tetsuro Shingo, Isao Dat. Injection of muscimol, a GABAa agonist into the anterior thalamic nucleus, suppresses hippocampal neurogenesis in amygdala-kindled rats. Neurological research. vol 31. issue 4. 2009-07-23. PMID:18826756. |
in this study, neurogenesis and the proliferation of astrocytes in the subgranular zone of the hippocampus were explored using unilateral amygdala-kindled rats with or without muscimol, a gamma-aminobutyric acid a (gabaa) agonist injection into the bilateral anterior thalamic nuclei (an). |
2009-07-23 |
2023-08-12 |
rat |
Desiree L Krebs-Kraft, Gail Rauw, Glen B Baker, Marise B Paren. Zero net flux estimates of septal extracellular glucose levels and the effects of glucose on septal extracellular GABA levels. European journal of pharmacology. vol 611. issue 1-3. 2009-07-23. PMID:19345207. |
although hippocampal infusions of glucose enhance memory, we have found repeatedly that septal glucose infusions impair memory when gamma-aminobutyric acid (gaba) receptors are activated. |
2009-07-23 |
2023-08-12 |
rat |
Desiree L Krebs-Kraft, Gail Rauw, Glen B Baker, Marise B Paren. Zero net flux estimates of septal extracellular glucose levels and the effects of glucose on septal extracellular GABA levels. European journal of pharmacology. vol 611. issue 1-3. 2009-07-23. PMID:19345207. |
for instance, hippocampal glucose infusions reverse the memory-impairing effects of co-infusions of the gaba agonist muscimol, whereas septal glucose infusions exacerbate memory deficits produced by muscimol. |
2009-07-23 |
2023-08-12 |
rat |
Eva Mikics, Judit Vas, Mano Aliczki, Jozsef Halasz, Jozsef Halle. Interactions between the anxiogenic effects of CB1 gene disruption and 5-HT3 neurotransmission. Behavioural pharmacology. vol 20. issue 3. 2009-07-23. PMID:19421027. |
neuroanatomical findings revealed that cb1 cannabinoid and 5-ht3 receptors are coexpressed by a subtype of gamma-aminobutyric acid (gaba)ergic interneurons in the prefrontal cortex, hippocampus, and basolateral amygdala, three brain regions that are crucial for the control of anxiety. |
2009-07-23 |
2023-08-12 |
mouse |
Omar A Ramírez, René L Vidal, Judith A Tello, Karina J Vargas, Stefan Kindler, Steffen Härtel, Andrés Couv. Dendritic assembly of heteromeric gamma-aminobutyric acid type B receptor subunits in hippocampal neurons. The Journal of biological chemistry. vol 284. issue 19. 2009-07-21. PMID:19276079. |
dendritic assembly of heteromeric gamma-aminobutyric acid type b receptor subunits in hippocampal neurons. |
2009-07-21 |
2023-08-12 |
Not clear |
Omar A Ramírez, René L Vidal, Judith A Tello, Karina J Vargas, Stefan Kindler, Steffen Härtel, Andrés Couv. Dendritic assembly of heteromeric gamma-aminobutyric acid type B receptor subunits in hippocampal neurons. The Journal of biological chemistry. vol 284. issue 19. 2009-07-21. PMID:19276079. |
to discriminate between these possibilities we studied the association of gaba(b)r subunits in dendrites of hippocampal neurons combining live fluorescence microscopy, biochemistry, quantitative colocalization, and bimolecular fluorescent complementation. |
2009-07-21 |
2023-08-12 |
Not clear |
Yoko Tominaga, Michinori Ichikawa, Takashi Tominag. Membrane potential response profiles of CA1 pyramidal cells probed with voltage-sensitive dye optical imaging in rat hippocampal slices reveal the impact of GABA(A)-mediated feed-forward inhibition in signal propagation. Neuroscience research. vol 64. issue 2. 2009-07-21. PMID:19428695. |
membrane potential response profiles of ca1 pyramidal cells probed with voltage-sensitive dye optical imaging in rat hippocampal slices reveal the impact of gaba(a)-mediated feed-forward inhibition in signal propagation. |
2009-07-21 |
2023-08-12 |
rat |
Chester J Siok, Charles P Taylor, Mihály Hajó. Anxiolytic profile of pregabalin on elicited hippocampal theta oscillation. Neuropharmacology. vol 56. issue 2. 2009-07-01. PMID:18930748. |
our findings suggest that pregabalin may alter evoked theta frequency activity in the hippocampus by reducing neurotransmitter-mediated activation of either the septal nucleus or the hippocampus, and that its actions are unlikely to be mediated by direct activation of gaba neurotransmitter systems. |
2009-07-01 |
2023-08-12 |
rat |
E Martín-García, S Darbra, M Pallaré. Neonatal finasteride induces anxiogenic-like profile and deteriorates passive avoidance in adulthood after intrahippocampal neurosteroid administration. Neuroscience. vol 154. issue 4. 2009-06-29. PMID:18539400. |
fluctuations in neonatal allop affect the aversive learning and the anxiety-related behavior in adulthood, and this effect could be in part mediated by alterations of the mature functions of the hippocampus, possibly via the gaba(a) receptor. |
2009-06-29 |
2023-08-12 |
rat |
Christine Winter, Anais Djodari-Irani, Reinhard Sohr, Rudolf Morgenstern, Joram Feldon, Georg Juckel, Urs Meye. Prenatal immune activation leads to multiple changes in basal neurotransmitter levels in the adult brain: implications for brain disorders of neurodevelopmental origin such as schizophrenia. The international journal of neuropsychopharmacology. vol 12. issue 4. 2009-06-26. PMID:18752727. |
in addition, a specific reduction of the inhibitory amino acid taurine in the hippocampus was noted in prenatally polyi:c-exposed offspring relative to controls, whereas central glutamate and gamma-aminobutyric acid (gaba) content was largely unaffected by prenatal immune activation. |
2009-06-26 |
2023-08-12 |
mouse |
Victoria A L Seymour, Andrea B Everitt, M Louise Tierne. Differential drug responses on native GABA(A) receptors revealing heterogeneity in extrasynaptic populations in cultured hippocampal neurons. The Journal of membrane biology. vol 227. issue 3. 2009-06-26. PMID:19153634. |
differential drug responses on native gaba(a) receptors revealing heterogeneity in extrasynaptic populations in cultured hippocampal neurons. |
2009-06-26 |
2023-08-12 |
rat |
Hiroko Bannai, Sabine Lévi, Claude Schweizer, Takafumi Inoue, Thomas Launey, Victor Racine, Jean-Baptiste Sibarita, Katsuhiko Mikoshiba, Antoine Trille. Activity-dependent tuning of inhibitory neurotransmission based on GABAAR diffusion dynamics. Neuron. vol 62. issue 5. 2009-06-26. PMID:19524526. |
we report here that neuronal activity modifies diffusion properties of type-a gaba receptors (gaba(a)r) in cultured hippocampal neurons: enhanced excitatory synaptic activity decreases the cluster size of gaba(a)rs and reduces gabaergic mipsc. |
2009-06-26 |
2023-08-12 |
Not clear |