| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Frances Fangjia Lu, Ping Su, Fang Liu, Zafiris J Daskalaki. Activation of GABA(B) receptors inhibits protein kinase B/glycogen synthase kinase 3 signaling. Molecular brain. vol 5. 2013-05-15. PMID:23192081. |
agonist stimulation of gaba(b) receptors enhances the phosphorylation of akt (thr-308) and enhances the phosphorylation of gsk-3α (ser-21)/β (ser-9) in both hek-293t cells expressing gaba(b) receptors and rat hippocampal slices. |
2013-05-15 |
2023-08-12 |
rat |
| M P Lorenzo, A Navarrete, C Balderas, A Garci. Optimization and validation of a CE-LIF method for amino acid determination in biological samples. Journal of pharmaceutical and biomedical analysis. vol 73. 2013-05-07. PMID:22482900. |
in hippocampus tissue the method was validated for the neurotransmitters: gamma-aminobutyric acid, l-glutamine, glycine, l-glutamate and l-aspartate. |
2013-05-07 |
2023-08-12 |
mouse |
| Maddalena D Caiati, Enrico Cherubin. Fluoxetine impairs GABAergic signaling in hippocampal slices from neonatal rats. Frontiers in cellular neuroscience. vol 7. 2013-05-06. PMID:23641199. |
the immature hippocampus is characterized by an early type of network activity, the so-called giant depolarizing potentials (gdps), generated by the synergistic action of glutamate and gaba, both depolarizing and excitatory. |
2013-05-06 |
2023-08-12 |
human |
| Lara Montes de Oca, Margarita Moreno, Diana Cardona, Leticia Campa, Cristina Suñol, Mireia Galofré, Pilar Flores, Fernando Sánchez-Sante. Long term compulsivity on the 5-choice serial reaction time task after acute Chlorpyrifos exposure. Toxicology letters. vol 216. issue 2-3. 2013-05-03. PMID:23194828. |
the cpf group also exhibited increased levels of dopamine metabolism in the hippocampus and decreased levels of gamma-aminobutyric acid (gaba) and glutamate in the striatum compared to the vehicle group. |
2013-05-03 |
2023-08-12 |
rat |
| V V Grigoriev, L N Petrova, A V Gabrelian, V L Zamoyski, T P Serkova, S O Bachuri. Effect of somatostatin on presynaptic and postsynaptic glutamate receptors and postsynaptic GABA receptors in the neurons of rat brain. Bulletin of experimental biology and medicine. vol 154. issue 1. 2013-05-03. PMID:23330078. |
somatostatin potentiates ampa receptors and inhibits hippocampal nmda receptors in the entire range of examined concentrations (10(-14)-10(-7) m); it also potentiates or inhibits gaba receptor currents in a concentration-dependent manner. |
2013-05-03 |
2023-08-12 |
rat |
| Marianne Renner, Claude Schweizer, Hiroko Bannai, Antoine Triller, Sabine Lév. Diffusion barriers constrain receptors at synapses. PloS one. vol 7. issue 8. 2013-05-01. PMID:22912780. |
to address this question, we studied the membrane diffusion of the γ-aminobutyric acid type a receptor (gaba(a)r) subunits clustered (γ2) or not (α5) at inhibitory synapses in rat hippocampal dissociated neurons. |
2013-05-01 |
2023-08-12 |
rat |
| Yan Deng, Wei Wang, Pingfeng Yu, Zhijiang Xi, Lijian Xu, Xiaolong Li, Nongyue H. Comparison of taurine, GABA, Glu, and Asp as scavengers of malondialdehyde in vitro and in vivo. Nanoscale research letters. vol 8. issue 1. 2013-04-29. PMID:23618076. |
it was shown that mda concentration was decreased significantly, and the activities of sod and gsh-px were increased significantly in the cerebral cortex and hippocampus of acute epileptic state rats, after the administration of taurine and gaba. |
2013-04-29 |
2023-08-12 |
rat |
| Akeo Kurumaji, Toru Nishikaw. An anxiogenic drug, FG 7142, induced an increase in mRNA of Btg2 and Adamts1 in the hippocampus of adult mice. Behavioral and brain functions : BBF. vol 8. 2013-04-23. PMID:22913326. |
the hippocampus is a crucial brain area involved in the neural circuits of the pathophysiology of anxiety and stress-related disorders, and gaba is one of most important neurotransmitters related to these disorders. |
2013-04-23 |
2023-08-12 |
mouse |
| Wucheng Tao, Matthew H Higgs, William J Spain, Christopher B Ranso. Postsynaptic GABAB receptors enhance extrasynaptic GABAA receptor function in dentate gyrus granule cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 9. 2013-04-22. PMID:23447585. |
to investigate an interaction between postsynaptic gaba(b) and gaba(a) receptors, we recorded gaba(a) currents elicited by exogenous gaba (10 μm) from dentate gyrus granule cells (dggcs) in adult rat hippocampal slices. |
2013-04-22 |
2023-08-12 |
rat |
| Agnieszka I Wlodarczyk, Sergiy Sylantyev, Murray B Herd, Flavie Kersanté, Jeremy J Lambert, Dmitri A Rusakov, Astrid C E Linthorst, Alexey Semyanov, Delia Belelli, Ivan Pavlov, Matthew C Walke. GABA-independent GABAA receptor openings maintain tonic currents. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 9. 2013-04-22. PMID:23447601. |
here we show that in rat dentate granule cells in ex vivo hippocampal slices, tonic currents are predominantly generated by gaba-independent gaba(a) receptor openings. |
2013-04-22 |
2023-08-12 |
rat |
| Agnieszka I Wlodarczyk, Sergiy Sylantyev, Murray B Herd, Flavie Kersanté, Jeremy J Lambert, Dmitri A Rusakov, Astrid C E Linthorst, Alexey Semyanov, Delia Belelli, Ivan Pavlov, Matthew C Walke. GABA-independent GABAA receptor openings maintain tonic currents. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 9. 2013-04-22. PMID:23447601. |
when slices are perfused with 200 nm gaba, a concentration that is comparable to csf concentrations but is twice that measured by us in the hippocampus in vivo using zero-net-flux microdialysis, negligible gaba is detected by dentate granule cells. |
2013-04-22 |
2023-08-12 |
rat |
| Carmen Martínez-Cué, Paula Martínez, Noemí Rueda, Rebeca Vidal, Susana García, Verónica Vidal, Andrea Corrales, Juan A Montero, Ángel Pazos, Jesús Flórez, Rodolfo Gasser, Andrew W Thomas, Michael Honer, Frédéric Knoflach, Jose Luis Trejo, Joseph G Wettstein, Maria-Clemencia Hernánde. Reducing GABAA α5 receptor-mediated inhibition rescues functional and neuromorphological deficits in a mouse model of down syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 9. 2013-04-22. PMID:23447605. |
we show that chronic treatment of these mice with ro4938581 (3-bromo-10-(difluoromethyl)-9h-benzo[f]imidazo[1,5-a][1,2,4]triazolo[1,5-d][1,4]diazepine), a selective gaba(a) α5 negative allosteric modulator (nam), rescued their deficits in spatial learning and memory, hippocampal synaptic plasticity, and adult neurogenesis. |
2013-04-22 |
2023-08-12 |
mouse |
| J C Damborsky, U H Winzer-Serha. Effects of sex and chronic neonatal nicotine treatment on Na²⁺/K⁺/Cl⁻ co-transporter 1, K⁺/Cl⁻ co-transporter 2, brain-derived neurotrophic factor, NMDA receptor subunit 2A and NMDA receptor subunit 2B mRNA expression in the postnatal rat hippocampus. Neuroscience. vol 225. 2013-04-16. PMID:22982626. |
these results suggest that differential maturation of gaba(a)r-mediated responses result in sex-specific sensitivity to nicotine during early postnatal development, potentially explaining the differential long-term effects of cnn on hippocampal function. |
2013-04-16 |
2023-08-12 |
human |
| Szu-Han Wang, Peter S B Finnie, Oliver Hardt, Karim Nade. Dorsal hippocampus is necessary for novel learning but sufficient for subsequent similar learning. Hippocampus. vol 22. issue 11. 2013-04-11. PMID:22593084. |
we found that dorsal hippocampus infusions of voltage-dependent calcium channel blockers or the inhibitory neurotransmitter gamma-aminobutyric acid (gaba) agonist impaired the first, not the second contextual learning. |
2013-04-11 |
2023-08-12 |
Not clear |
| Kumar Venkatesan, Philippe Alix, Alice Marquet, Melissa Doupagne, Isabelle Niespodziany, Bernard Rogister, Vincent Seuti. Altered balance between excitatory and inhibitory inputs onto CA1 pyramidal neurons from SV2A-deficient but not SV2B-deficient mice. Journal of neuroscience research. vol 90. issue 12. 2013-04-11. PMID:22847229. |
because excitatory and inhibitory inputs play a major role in controlling neuronal excitability in the hippocampus, we examined the effects of sv2a and/or sv2b deletions on glutamatergic and gaba(a) neurotransmission in hippocampal ca1 pyramidal neurons. |
2013-04-11 |
2023-08-12 |
mouse |
| Aarti Kuver, Hui Shen, Sheryl S Smit. Regulation of the surface expression of α4β2δ GABAA receptors by high efficacy states. Brain research. vol 1463. 2013-04-08. PMID:22609410. |
hek-293 cells or cultured hippocampal neurons were transfected with α4fβ2δ and treated 24h later with gaba agonists, thp, gaba plus thp or vehicle (0.01% dmso) for 0.5 h-48 h. immunocytochemistry was performed under both non-permeabilized and permeabilized conditions to detect surface and intracellular labeling, respectively, using confocal microscopy. |
2013-04-08 |
2023-08-12 |
Not clear |
| Naomi Lewin, Emre Aksay, Colleen E Clanc. Computational modeling reveals dendritic origins of GABA(A)-mediated excitation in CA1 pyramidal neurons. PloS one. vol 7. issue 10. 2013-04-04. PMID:23071770. |
we undertook a computational modeling approach to determine plausible ionic mechanisms of gaba(a)-dependent excitation in isolated post-synaptic ca1 hippocampal neurons because it may constitute a trigger for pathological synchronous epileptiform discharge. |
2013-04-04 |
2023-08-12 |
Not clear |
| Rémi Bos, Laurent Vina. Glucose is an adequate energy substrate for the depolarizing action of GABA and glycine in the neonatal rat spinal cord in vitro. Journal of neurophysiology. vol 107. issue 11. 2013-04-02. PMID:22457452. |
this widely accepted phenomenon was recently challenged by experiments showing that the depolarizing action of gaba on neonatal hippocampus and neocortex in vitro was prevented by adding energy substrates (es), such as the ketone body metabolite dl-β-hydroxybutyric acid (dl-bhb), lactate, or pyruvate to the artificial cerebrospinal fluid (acsf). |
2013-04-02 |
2023-08-12 |
rat |
| Maddalena Delma Caiat. Is GABA co-released with glutamate from hippocampal mossy fiber terminals? The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 5. 2013-04-02. PMID:23365214. |
is gaba co-released with glutamate from hippocampal mossy fiber terminals? |
2013-04-02 |
2023-08-12 |
Not clear |
| Sarah M Simpson, Andrea J Hickey, Glen B Baker, James N Reynolds, Richard J Beninge. The antidepressant phenelzine enhances memory in the double Y-maze and increases GABA levels in the hippocampus and frontal cortex of rats. Pharmacology, biochemistry, and behavior. vol 102. issue 1. 2013-03-14. PMID:22503968. |
the antidepressant phenelzine enhances memory in the double y-maze and increases gaba levels in the hippocampus and frontal cortex of rats. |
2013-03-14 |
2023-08-12 |
rat |