Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
T Dalkara, E Saederup, R F Squires, K Krnjevi. Iontophoretic studies on rat hippocampus with some novel GABA antagonists. Life sciences. vol 39. issue 5. 1986-09-17. PMID:2874465. |
twelve substances which appear to be gaba antagonists, judging by their ability to reverse the inhibitory effect of gaba on 35s-tbps binding to rat brain membranes, were tested iontophoretically on population spikes in the rat hippocampus. |
1986-09-17 |
2023-08-11 |
rat |
T J McCown, G D Frye, G R Brees. Evidence for site specific ethanol actions in the CNS. Alcohol and drug research. vol 6. issue 6. 1986-09-17. PMID:3939188. |
when the neuroactive amino acids, glycine, glutamate, aspartate, gaba and taurine, were measured in the cortex, striatum, hippocampus, midbrain, and brain stem of acute or chronic ethanol-treated rats, site specific changes were observed for glutamate, glycine, and aspartate. |
1986-09-17 |
2023-08-11 |
rat |
J H Schneiderman, J C Evan. Effects of anticonvulsants on penicillin-induced bursting in guinea pig hippocampal slices. Epilepsia. vol 27. issue 4. 1986-08-20. PMID:3087742. |
the effects of gamma-aminobutyric acid (gaba) and six anticonvulsants on penicillin-induced bursting were compared in guinea pig hippocampal slices. |
1986-08-20 |
2023-08-11 |
Not clear |
A G Chapman, M J Halsey, G P Hart, N P Luff, B S Meldrum, B Wardley-Smit. Regional amino acid concentration in the brains of rats exposed to high pressures. Journal of neurochemistry. vol 47. issue 1. 1986-07-23. PMID:3711908. |
at 85 ata glutamine content increased in hippocampus, striatum, cerebellum, and substantia nigra, and gamma-aminobutyric acid content increased in hippocampus. |
1986-07-23 |
2023-08-11 |
rat |
C Briving, I Jacobson, A Hamberger, P Kjellstrand, K G Haglid, L E Rosengre. Chronic effects of perchloroethylene and trichloroethylene on the gerbil brain amino acids and glutathione. Neurotoxicology. vol 7. issue 1. 1986-07-14. PMID:2872637. |
vermis posterior of cerebellum and hippocampus were used for measurement of high-affinity uptake and release of 3h-gamma-aminobutyric acid (gaba) and 14c-glutamate, as well as for determination of total free tissue amino acids and glutathione. |
1986-07-14 |
2023-08-11 |
Not clear |
C Briving, I Jacobson, A Hamberger, P Kjellstrand, K G Haglid, L E Rosengre. Chronic effects of perchloroethylene and trichloroethylene on the gerbil brain amino acids and glutathione. Neurotoxicology. vol 7. issue 1. 1986-07-14. PMID:2872637. |
the uptake of glutamate and gaba in cerebellum and hippocampus were unaffected after pce exposure to 120 ppm for 12 months. |
1986-07-14 |
2023-08-11 |
Not clear |
C Briving, I Jacobson, A Hamberger, P Kjellstrand, K G Haglid, L E Rosengre. Chronic effects of perchloroethylene and trichloroethylene on the gerbil brain amino acids and glutathione. Neurotoxicology. vol 7. issue 1. 1986-07-14. PMID:2872637. |
the potassium-stimulated release of glutamate and gaba was unaffected in hippocampal tissue slices from gerbils exposed to 50 and 150 ppm tce. |
1986-07-14 |
2023-08-11 |
Not clear |
F Zambotti, N Zonta, P Ferrario, L Zecca, P Mantegazz. Effects of 2-chloroadenosine on hippocampal GABA content and turnover. Journal of neural transmission. vol 65. issue 3-4. 1986-07-14. PMID:3711882. |
effects of 2-chloroadenosine on hippocampal gaba content and turnover. |
1986-07-14 |
2023-08-11 |
rat |
F Zambotti, N Zonta, P Ferrario, L Zecca, P Mantegazz. Effects of 2-chloroadenosine on hippocampal GABA content and turnover. Journal of neural transmission. vol 65. issue 3-4. 1986-07-14. PMID:3711882. |
the effects of 2-chloroadenosine (cado), a stable analog of adenosine, on gaba turnover rate and gaba content in the rat hippocampus in vivo have been studied. |
1986-07-14 |
2023-08-11 |
rat |
F Zambotti, N Zonta, P Ferrario, L Zecca, P Mantegazz. Effects of 2-chloroadenosine on hippocampal GABA content and turnover. Journal of neural transmission. vol 65. issue 3-4. 1986-07-14. PMID:3711882. |
the intracerebroventricular injection of cado reduced the gaba turnover rate in the hippocampus, as estimated from the rate of gaba accumulation after inhibition of gaba transaminase (gaba-t) by aminooxyacetic acid (aoaa). |
1986-07-14 |
2023-08-11 |
rat |
F Zambotti, N Zonta, P Ferrario, L Zecca, P Mantegazz. Effects of 2-chloroadenosine on hippocampal GABA content and turnover. Journal of neural transmission. vol 65. issue 3-4. 1986-07-14. PMID:3711882. |
the effect of cado on aoaa-induced accumulation of gaba in the hippocampus was blocked by the intraperitoneal injection of the adenosine receptor antagonist caffeine. |
1986-07-14 |
2023-08-11 |
rat |
F Zambotti, N Zonta, P Ferrario, L Zecca, P Mantegazz. Effects of 2-chloroadenosine on hippocampal GABA content and turnover. Journal of neural transmission. vol 65. issue 3-4. 1986-07-14. PMID:3711882. |
furthermore, cado at the dose of 5 micrograms per ventricle produced a significant decrease in gaba content in the hippocampus. |
1986-07-14 |
2023-08-11 |
rat |
M Schlander, M Frotsche. Non-pyramidal neurons in the guinea pig hippocampus. A combined Golgi-electron microscope study. Anatomy and embryology. vol 174. issue 1. 1986-06-19. PMID:2422985. |
the results are discussed in relation to recent immunocytochemical studies which have shown non-pyramidal neurons in the hippocampus to contain gamma-aminobutyric acid and/or various neuropeptides. |
1986-06-19 |
2023-08-11 |
Not clear |
M D Majewska, N L Harrison, R D Schwartz, J L Barker, S M Pau. Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor. Science (New York, N.Y.). vol 232. issue 4753. 1986-06-11. PMID:2422758. |
at concentrations between 10(-7) and 10(-5)m both steroids inhibited binding of the convulsant t-butylbicyclophosphorothionate to the gaba-receptor complex and increased the binding of the benzodiazepine flunitrazepam; they also stimulated chloride uptake (as measured by uptake of 36cl-) into isolated brain vesicles, and potentiated the inhibitory actions of gaba in cultured rat hippocampal and spinal cord neurons. |
1986-06-11 |
2023-08-11 |
rat |
T J Ashwood, H V Whea. Loss of inhibition in the CA1 region of the kainic acid lesioned hippocampus is not associated with changes in postsynaptic responses to GABA. Brain research. vol 367. issue 1-2. 1986-06-09. PMID:3008925. |
loss of inhibition in the ca1 region of the kainic acid lesioned hippocampus is not associated with changes in postsynaptic responses to gaba. |
1986-06-09 |
2023-08-11 |
Not clear |
T J Ashwood, H V Whea. Loss of inhibition in the CA1 region of the kainic acid lesioned hippocampus is not associated with changes in postsynaptic responses to GABA. Brain research. vol 367. issue 1-2. 1986-06-09. PMID:3008925. |
somatic and dendritic responses to gamma-aminobutyric acid (gaba) were recorded intracellularly from ca1 pyramidal cells in slices of the hippocampus ipsilateral and contralateral to a unilateral kainic acid lesion of the ca3 region. |
1986-06-09 |
2023-08-11 |
Not clear |
L Rönnbäck, E Hansson, A Cupello, M V Rapallino, J Zeuchner, L Rosengre. Neurotransmitter uptake in various brain regions of chronically morphinized rats. Neurochemical research. vol 11. issue 2. 1986-06-02. PMID:2871500. |
[3h]glutamate and [3h]gaba uptakes were also significantly lower, respectively, in frontal cortex, hippocampus and brain stem in intoxicated rats, while [3h]5-ht uptake was significantly lower in hypothalamus after morphine withdrawal. |
1986-06-02 |
2023-08-11 |
rat |
S J Korn, R Dingledin. Inhibition of GABA uptake in the rat hippocampal slice. Brain research. vol 368. issue 2. 1986-06-02. PMID:3697725. |
inhibition of gaba uptake in the rat hippocampal slice. |
1986-06-02 |
2023-08-11 |
rat |
S J Korn, R Dingledin. Inhibition of GABA uptake in the rat hippocampal slice. Brain research. vol 368. issue 2. 1986-06-02. PMID:3697725. |
pharmacological manipulations known to inhibit gaba uptake prolonged gaba-evoked conductance increases in ca1 pyramidal cells in the rat hippocampal slice preparation. |
1986-06-02 |
2023-08-11 |
rat |
S J Korn, R Dingledin. Inhibition of GABA uptake in the rat hippocampal slice. Brain research. vol 368. issue 2. 1986-06-02. PMID:3697725. |
these results demonstrate the presence of a functional gaba uptake system in the hippocampal slice. |
1986-06-02 |
2023-08-11 |
rat |