| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J A Kemp, G R Marshall, E H Wong, G N Woodruf. The affinities, potencies and efficacies of some benzodiazepine-receptor agonists, antagonists and inverse-agonists at rat hippocampal GABAA-receptors. British journal of pharmacology. vol 91. issue 3. 1987-09-16. PMID:3038246. |
the abilities of some benzodiazepine-receptor agonists, antagonists and inverse agonists to modulate the inhibitory potency of the gamma-aminobutyric acid (gaba)a-receptor agonist, isoguvacine, on the ca1 population spike recorded from slices of rat hippocampus, were determined. |
1987-09-16 |
2023-08-11 |
rat |
| J A Kemp, G R Marshall, E H Wong, G N Woodruf. The affinities, potencies and efficacies of some benzodiazepine-receptor agonists, antagonists and inverse-agonists at rat hippocampal GABAA-receptors. British journal of pharmacology. vol 91. issue 3. 1987-09-16. PMID:3038246. |
the maximum effects produced by diazepam, flunitrazepam, ro16-6028, ro17-1812, the antagonist, propyl-beta-carboline-3-carboxylate, and the inverse agonist, methyl-6, 7-dimethyl-4-ethyl-beta-carboline-3-carboxylate (dmcm), on the potency of isoguvacine in the hippocampal slice corresponded to the change in their affinities produced by the addition of gaba in the radioligand binding studies (gaba-shift). |
1987-09-16 |
2023-08-11 |
rat |
| F Zambotti, N Zonta, B Hafner, P Ferrario, L Zecca, P Mantegazz. Modification of GABA turnover in the striatum and hippocampus of the rat after zopiclone. Naunyn-Schmiedeberg's archives of pharmacology. vol 335. issue 5. 1987-09-11. PMID:3112588. |
modification of gaba turnover in the striatum and hippocampus of the rat after zopiclone. |
1987-09-11 |
2023-08-11 |
rat |
| F Zambotti, N Zonta, B Hafner, P Ferrario, L Zecca, P Mantegazz. Modification of GABA turnover in the striatum and hippocampus of the rat after zopiclone. Naunyn-Schmiedeberg's archives of pharmacology. vol 335. issue 5. 1987-09-11. PMID:3112588. |
the effects of zopiclone, a non-benzodiazepine compound that interacts with benzodiazepine receptors, on gaba turnover rate and gaba content in the rat striatum and hippocampus have been studied. |
1987-09-11 |
2023-08-11 |
rat |
| F Zambotti, N Zonta, B Hafner, P Ferrario, L Zecca, P Mantegazz. Modification of GABA turnover in the striatum and hippocampus of the rat after zopiclone. Naunyn-Schmiedeberg's archives of pharmacology. vol 335. issue 5. 1987-09-11. PMID:3112588. |
intraperitoneal administration of zopiclone reduced the gaba turnover rates in both the striatum and hippocampus, as estimated from the rate of gaba accumulation after inhibition of gaba transaminase by aminooxyacetic acid (aoaa). |
1987-09-11 |
2023-08-11 |
rat |
| F Zambotti, N Zonta, B Hafner, P Ferrario, L Zecca, P Mantegazz. Modification of GABA turnover in the striatum and hippocampus of the rat after zopiclone. Naunyn-Schmiedeberg's archives of pharmacology. vol 335. issue 5. 1987-09-11. PMID:3112588. |
the effect of zopiclone on aoaa-induced accumulation of gaba in the hippocampus and striatum was blocked by the intraperitoneal injection of the benzodiazepine receptor antagonist ro 15-3505. |
1987-09-11 |
2023-08-11 |
rat |
| F Zambotti, N Zonta, B Hafner, P Ferrario, L Zecca, P Mantegazz. Modification of GABA turnover in the striatum and hippocampus of the rat after zopiclone. Naunyn-Schmiedeberg's archives of pharmacology. vol 335. issue 5. 1987-09-11. PMID:3112588. |
furthermore, zopiclone slightly but significantly decreased gaba content in the hippocampus, the decrease being blocked by coadministration of the benzodiazepine receptor antagonist ro 15-1788. |
1987-09-11 |
2023-08-11 |
rat |
| E Swearengen, C Chavki. NMDA receptor antagonist D-APV depresses excitatory activity produced by normorphine in rat hippocampal slices. Neuroscience letters. vol 78. issue 1. 1987-09-01. PMID:2886961. |
these results suggest that both opiates and gaba receptor antagonists are able to unmask nmda receptors in the in vitro rat hippocampus slice preparation. |
1987-09-01 |
2023-08-11 |
rat |
| R Corradetti, M Ruggiero, V P Chiarugi, G Pepe. GABA-receptor stimulation enhances norepinephrine-induced polyphosphoinositide metabolism in rat hippocampal slices. Brain research. vol 411. issue 1. 1987-08-28. PMID:3038260. |
the effect of gamma-aminobutyric acid (gaba)receptor stimulation on norepinephrine (ne)-induced metabolism of polyphosphoinositides (pips) was studied in rat hippocampal slices. |
1987-08-28 |
2023-08-11 |
rat |
| L Ciesielski, S Simler, J Clement, P Mande. Effect of repeated convulsive seizures on brain gamma-aminobutyric acid metabolism in three sublines of mice differing by their response to acoustic stimulations. Journal of neurochemistry. vol 49. issue 1. 1987-07-21. PMID:3585331. |
in the rb1 subline, gaba steady-state levels are lower than in the rb3 subline in three of the 15 areas examined (cerebellum, anterior colliculus, and amygdala), whereas in the rb2 subline, steady-state levels are either higher (posterior colliculus and hippocampus) or lower (amygdala) than in the rb3 subline. |
1987-07-21 |
2023-08-11 |
mouse |
| G Bonanno, M Raiter. A carrier for GABA uptake exists on noradrenaline nerve endings in selective rat brain areas but not on serotonin terminals. Journal of neural transmission. vol 69. issue 1-2. 1987-07-16. PMID:3585321. |
gamma-aminobutyric acid (gaba) increased in a concentration-dependent way (3-300 microm) the basal release of tritium from rat cerebral cortex and hippocampus synaptosomes, prelabelled with 3h-noradrenaline (3h-na); however, gaba was ineffective on hypothalamic nerve endings. |
1987-07-16 |
2023-08-11 |
rat |
| A Pittaluga, M Raiter. GABAergic nerve terminals in rat hippocampus possess alpha 2-adrenoceptors regulating GABA release. Neuroscience letters. vol 76. issue 3. 1987-07-10. PMID:3035440. |
gabaergic nerve terminals in rat hippocampus possess alpha 2-adrenoceptors regulating gaba release. |
1987-07-10 |
2023-08-11 |
rat |
| A Pittaluga, M Raiter. GABAergic nerve terminals in rat hippocampus possess alpha 2-adrenoceptors regulating GABA release. Neuroscience letters. vol 76. issue 3. 1987-07-10. PMID:3035440. |
noradrenaline enhanced in a concentration-dependent way the basal release of endogenous gaba from superfused rat hippocampus synaptosomes. |
1987-07-10 |
2023-08-11 |
rat |
| A Pittaluga, M Raiter. GABAergic nerve terminals in rat hippocampus possess alpha 2-adrenoceptors regulating GABA release. Neuroscience letters. vol 76. issue 3. 1987-07-10. PMID:3035440. |
it is concluded that gabaergic nerve terminals in rat hippocampus possess adrenoceptors of the alpha 2-subtype whose activation causes enhancement of gaba release. |
1987-07-10 |
2023-08-11 |
rat |
| I Chaudieu, G Rondouin, M Chicheportiche, R Chicheportich. Presynaptic alteration of [3H]GABA transport in hippocampus by amygdala kindling. Neuroscience letters. vol 76. issue 3. 1987-07-10. PMID:3587763. |
presynaptic alteration of [3h]gaba transport in hippocampus by amygdala kindling. |
1987-07-10 |
2023-08-11 |
rat |
| I Chaudieu, G Rondouin, M Chicheportiche, R Chicheportich. Presynaptic alteration of [3H]GABA transport in hippocampus by amygdala kindling. Neuroscience letters. vol 76. issue 3. 1987-07-10. PMID:3587763. |
gamma-amino[2,3-3h]butyric acid ([3h]gaba) transport was investigated in hippocampal synaptosomes prepared from amygdala kindled rats. |
1987-07-10 |
2023-08-11 |
rat |
| K Shinoda, M Tohyama, Y Shiotan. Hippocampofugal gamma-aminobutyric acid (GABA)-containing neuron system in the rat: a study using a double-labeling method that combines retrograde tracing and immunocytochemistry. Brain research. vol 409. issue 1. 1987-07-07. PMID:3555700. |
the hypothesis was confirmed by the double-labeling method: injection of the biotinylated wheat germ agglutinin (b-wga) into the septum resulted in labeling numerous neurons in the hippocampus and some of them also showed gaba-like immunoreactivity by the simultaneous immunostaining with the antiserum against gaba. |
1987-07-07 |
2023-08-11 |
rat |
| T L Perry, V W Yong, C Bergeron, S Hansen, K Jone. Amino acids, glutathione, and glutathione transferase activity in the brains of patients with Alzheimer's disease. Annals of neurology. vol 21. issue 4. 1987-06-19. PMID:3579218. |
the mean contents of gamma-aminobutyric acid (gaba), and of the gaba dipeptide homocarnosine, were significantly reduced in frontal and occipital cortices and in hippocampus of the autopsied brains of ad patients compared to control patients without neurological disease. |
1987-06-19 |
2023-08-11 |
Not clear |
| P F Worley, J M Baraban, M McCarren, S H Snyder, B E Alge. Cholinergic phosphatidylinositol modulation of inhibitory, G protein-linked neurotransmitter actions: electrophysiological studies in rat hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 84. issue 10. 1987-06-18. PMID:3106971. |
in electrophysiological studies using the rat hippocampal slice preparation, cholinergic agonists and phorbol 12,13-diacetate, a stimulator of protein kinase c, block the inhibitory actions of baclofen, a gamma-aminobutyric acid b receptor agonist, and adenosine. |
1987-06-18 |
2023-08-11 |
rat |
| L J Burdette, R S Dye. Differential effects of caffeine, picrotoxin, and pentylenetetrazol on hippocampal afterdischarge activity and wet dog shakes. Experimental neurology. vol 96. issue 2. 1987-06-02. PMID:3569462. |
as picrotoxin and pentylenetetrazol are known gamma-aminobutyric acid (gaba) antagonists, the results suggest that gaba is involved minimally, if at all, in the hippocampal afterdischarge sequence. |
1987-06-02 |
2023-08-11 |
rat |