| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J C Rekling, H Jahnsen, A Mosfeldt Laurse. The effect of two lipophilic gamma-aminobutyric acid uptake blockers in CA1 of the rat hippocampal slice. British journal of pharmacology. vol 99. issue 1. 1990-06-07. PMID:2331564. |
we have investigated the effect of these two uptake inhibitors on the responses to exogenous gaba and on gaba-mediated inhibitory synaptic potentials in pyramidal neurones of the ca1 region in the rat hippocampal slice. |
1990-06-07 |
2023-08-11 |
rat |
| P Kugler, G Baie. Microphotometric determination of enzymes in brain sections. II. GABA transaminase. Histochemistry. vol 93. issue 5. 1990-06-07. PMID:2332351. |
the tetrazolium salt procedure of van gelder (1965) for the demonstration of gaba transaminase (gabat; the most important gaba degrading enzyme) was adapted for microphotometric measurements of gabat activities in brain sections using the hippocampus of rats as selected brain region. |
1990-06-07 |
2023-08-11 |
rat |
| W J McBride, J M Murphy, L Lumeng, T K L. Serotonin, dopamine and GABA involvement in alcohol drinking of selectively bred rats. Alcohol (Fayetteville, N.Y.). vol 7. issue 3. 1990-06-05. PMID:2184832. |
neurochemical data indicate that high alcohol-seeking behavior (when compared with data from rats with low alcohol-seeking characteristics) is associated with: a) lower (10-20%; p less than 0.05) contents of 5-ht in certain limbic regions (e.g., nucleus accumbens, frontal cortex, hypothalamus and hippocampus); b) a lower (10-15%; p less than 0.05) content of da in the nucleus accumbens; c) higher (20-35%; p less than 0.05) densities of 5-ht1a binding sites in some limbic regions (e.g., medial nucleus accumbens, medial prefrontal cortex and ventral hippocampus); and d) a greater (20-50%) density of gaba axon terminals in the nucleus accumbens. |
1990-06-05 |
2023-08-11 |
rat |
| W Kamphuis, E Huisman, A M Dreijer, W E Ghijsen, M Verhage, F H Lopes da Silv. Kindling increases the K(+)-evoked Ca2(+)-dependent release of endogenous GABA in area CA1 of rat hippocampus. Brain research. vol 511. issue 1. 1990-06-04. PMID:2331617. |
kindling increases the k(+)-evoked ca2(+)-dependent release of endogenous gaba in area ca1 of rat hippocampus. |
1990-06-04 |
2023-08-11 |
rat |
| R Radian, O P Ottersen, J Storm-Mathisen, M Castel, B I Kanne. Immunocytochemical localization of the GABA transporter in rat brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 10. issue 4. 1990-05-25. PMID:2329379. |
polyclonal antibodies were raised against the gaba transporter (gaba-tp) purified from rat brain tissue (radian et al., 1986) and used for immunocytochemical localization of the antigen in several rat brain areas, including the cerebellum, hippocampus, substantia nigra, and cerebral cortex. |
1990-05-25 |
2023-08-11 |
rat |
| M Virgili, O Barnabei, A Contestabil. Regional maturation of neurotransmitter-related and glial markers during postnatal development in the rat. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 8. issue 2. 1990-05-24. PMID:1970217. |
neurotransmitter-related (choline acetyltransferase, acetylcholinesterase, glutamate decarboxylase, l-glutamate and gaba high affinity uptake) and glial neurochemical markers (glutamine synthetase, beta-alanine uptake and 2',3' cyclic nucleotide phosphohydrolase) have been quantitatively assayed in various regions of the rat cns during normal postnatal development: spinal cord, cerebellum, superior colliculus, hippocampus, striatum, visual cortex, frontal sensory-motor cortex and prefrontal cortex. |
1990-05-24 |
2023-08-11 |
rat |
| E O Alvarez, A M Banza. Behavioral effects of GABA in the hippocampal formation: functional interaction with histamine. Behavioural brain research. vol 37. issue 2. 1990-05-21. PMID:2157460. |
some behavioral effects of gaba in the hippocampus and its probable interaction with histamine in adult male rats were studied. |
1990-05-21 |
2023-08-11 |
rat |
| E O Alvarez, A M Banza. Behavioral effects of GABA in the hippocampal formation: functional interaction with histamine. Behavioural brain research. vol 37. issue 2. 1990-05-21. PMID:2157460. |
1, rats were implanted unilaterally into the ventral hippocampus and they were microinjected with increasing doses of gaba. |
1990-05-21 |
2023-08-11 |
rat |
| E O Alvarez, A M Banza. Behavioral effects of GABA in the hippocampal formation: functional interaction with histamine. Behavioural brain research. vol 37. issue 2. 1990-05-21. PMID:2157460. |
2, the implanted rats were microinjected into the ventral hippocampus with gamma-vinyl-gaba (gvg), an inhibitor of the metabolizing enzyme of gaba and picrotoxin and bicuculline, both antagonists of gaba. |
1990-05-21 |
2023-08-11 |
rat |
| E O Alvarez, A M Banza. Behavioral effects of GABA in the hippocampal formation: functional interaction with histamine. Behavioural brain research. vol 37. issue 2. 1990-05-21. PMID:2157460. |
results showed that the gvg injection into the hippocampus augmented the endogenous levels of gaba. |
1990-05-21 |
2023-08-11 |
rat |
| J Walden, E J Speckmann, D Bingmann, H Strau. Augmentation of N-methyl-D-aspartate induced depolarizations by GABA in neocortical and archicortical neurons. Brain research. vol 510. issue 1. 1990-05-21. PMID:2182180. |
the influence of the inhibitory transmitter gamma-aminobutyric acid (gaba) on depolarizations elicited by the excitatory amino acid n-methyl-d-aspartate (nmda) was tested in neurons of organotypic neocortical tissue cultures (newborn rat) and in ca3 neurons of the hippocampal slice (guinea pig). |
1990-05-21 |
2023-08-11 |
rat |
| A V Iarkov, V V Vorob'ev, A A Gal'chenko, G I Kovale. [The electrical activity of the hippocampus in rats centrally administered GABA agonists and antagonists]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 75. issue 12. 1990-04-26. PMID:2560722. |
[the electrical activity of the hippocampus in rats centrally administered gaba agonists and antagonists]. |
1990-04-26 |
2023-08-11 |
rat |
| A V Iarkov, V V Vorob'ev, A A Gal'chenko, G I Kovale. [The electrical activity of the hippocampus in rats centrally administered GABA agonists and antagonists]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 75. issue 12. 1990-04-26. PMID:2560722. |
in unrestrained rats, frequency ranges of dorsal hippocampus electrograms were studied after intraventricular injections of the gaba, muscimol, baclofen, bicuculline and picrotoxin. |
1990-04-26 |
2023-08-11 |
rat |
| b' M Lass\\xc3\\xa1nov\\xc3\\xa1, T Tursk\\xc3\\xbd, D Homerov\\xc3\\xa. [The effect of ethanol on gamma-aminobutyric acid in the brain]. Bratislavske lekarske listy. vol 90. issue 12. 1990-04-26. PMID:2576392.' |
the activity of gaba transaminase did not change and the activity of glutamine synthetase decreased only in the hippocampus. |
1990-04-26 |
2023-08-11 |
Not clear |
| S F Ali, G D Newport, A C Scallet, K W Gee, M G Paule, R M Brown, W Slikke. Effects of chronic delta-9-tetrahydrocannabinol (THC) administration on neurotransmitter concentrations and receptor binding in the rat brain. Neurotoxicology. vol 10. issue 3. 1990-04-12. PMID:2576303. |
two months after the cessation of chronic administration, there was a significant decrease in gaba receptor binding in the hippocampus of animals in the high dose group. |
1990-04-12 |
2023-08-11 |
rat |
| S F Ali, G D Newport, A C Scallet, K W Gee, M G Paule, R M Brown, W Slikke. Effects of chronic delta-9-tetrahydrocannabinol (THC) administration on neurotransmitter concentrations and receptor binding in the rat brain. Neurotoxicology. vol 10. issue 3. 1990-04-12. PMID:2576303. |
in an attempt to replicate the gaba receptor binding changes and also to determine the [35s]tbps binding in hippocampus, we designed experiment 2. |
1990-04-12 |
2023-08-11 |
rat |
| S F Ali, G D Newport, A C Scallet, K W Gee, M G Paule, R M Brown, W Slikke. Effects of chronic delta-9-tetrahydrocannabinol (THC) administration on neurotransmitter concentrations and receptor binding in the rat brain. Neurotoxicology. vol 10. issue 3. 1990-04-12. PMID:2576303. |
results from this experiment failed to replicate the dose-dependent effect of thc on gaba receptor binding in hippocampus. |
1990-04-12 |
2023-08-11 |
rat |
| J Yanai, F Fares, M Gavish, Z Greenfeld, Y Katz, G Marcovici, C G Pick, Y Rogel-Fuchs, A Weizma. Neural and behavioral alterations after early exposure to phenobarbital. Neurotoxicology. vol 10. issue 3. 1990-04-12. PMID:2696900. |
neurochemical studies on the hippocampus revealed the following alterations: (a) decrease in ne level and the number of the ne cell bodies (b) no change in the serotonergic system (c) an increase in muscarinic receptors bmax in the hippocampus; (d) no changes in gaba and benzodiazepine receptors. |
1990-04-12 |
2023-08-11 |
mouse |
| U Wahnschaffe, W Lösche. Lesions of the deep prepiriform cortex ('area tempestas') in rats do not affect the convulsant action of systemically administered bicuculline. Neuroscience letters. vol 108. issue 1-2. 1990-03-19. PMID:2304624. |
the gamma-aminobutyric acid (gaba) antagonist, bicuculline, induces generalized motor seizures when injected into a discrete site ('area tempestas') in the deep prepiriform cortex at concentrations considerably lower than those that induce convulsions from closely adjacent areas or other forebrain sites such as amygdala and hippocampus. |
1990-03-19 |
2023-08-11 |
rat |
| D P Artemenko, V D Gerasimo. [Stimulating effect of gamma-aminobutyric acid on rat hippocampal neurons in vitro]. Fiziologicheskii zhurnal. vol 35. issue 6. 1990-03-15. PMID:2612621. |
[stimulating effect of gamma-aminobutyric acid on rat hippocampal neurons in vitro]. |
1990-03-15 |
2023-08-11 |
rat |