| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J H Ye, T Hunt, W H Wu, J J McArdl. Ondansetron modulates GABA(A) current of rat central nervous system neurons. European journal of pharmacology. vol 337. issue 1. 1998-01-26. PMID:9389385. |
we examined the effect of ondansetron, a 5-ht3 receptor antagonist, on the whole cell current response of freshly isolated hypothalamic and hippocampal neurons of rats to gamma-aminobutyric acid (gaba). |
1998-01-26 |
2023-08-12 |
rat |
| M A Coull, A T Johnston, R G Pertwee, S N Davie. Action of delta-9-tetrahydrocannabinol on GABA(A) receptor-mediated responses in a grease-gap recording preparation of the rat hippocampal slice. Neuropharmacology. vol 36. issue 10. 1998-01-22. PMID:9423926. |
action of delta-9-tetrahydrocannabinol on gaba(a) receptor-mediated responses in a grease-gap recording preparation of the rat hippocampal slice. |
1998-01-22 |
2023-08-12 |
rat |
| M A Coull, A T Johnston, R G Pertwee, S N Davie. Action of delta-9-tetrahydrocannabinol on GABA(A) receptor-mediated responses in a grease-gap recording preparation of the rat hippocampal slice. Neuropharmacology. vol 36. issue 10. 1998-01-22. PMID:9423926. |
we have investigated the effects of delta-9-tetrahydrocannabinol (delta-9-thc) on gamma-aminobutyric acid (gaba) receptor-mediated responses in a grease-gap recording preparation of the rat hippocampus. |
1998-01-22 |
2023-08-12 |
rat |
| M A Coull, A T Johnston, R G Pertwee, S N Davie. Action of delta-9-tetrahydrocannabinol on GABA(A) receptor-mediated responses in a grease-gap recording preparation of the rat hippocampal slice. Neuropharmacology. vol 36. issue 10. 1998-01-22. PMID:9423926. |
since gaba is the substrate of an avid uptake system, but muscimol is not, the results are consistent with the suggestion that delta-9-thc inhibits the uptake of gaba in the hippocampus. |
1998-01-22 |
2023-08-12 |
rat |
| E Fedele, A Conti, M Raiter. The glutamate receptor/NO/cyclic GMP pathway in the hippocampus of freely moving rats: modulation by cyclothiazide, interaction with GABA and the behavioural consequences. Neuropharmacology. vol 36. issue 10. 1998-01-22. PMID:9423927. |
the glutamate receptor/no/cyclic gmp pathway in the hippocampus of freely moving rats: modulation by cyclothiazide, interaction with gaba and the behavioural consequences. |
1998-01-22 |
2023-08-12 |
rat |
| E Fedele, G Varnier, M Raiter. In vivo microdialysis study of GABA(A) and GABA(B) receptors modulating the glutamate receptor/NO/cyclic GMP pathway in the rat hippocampus. Neuropharmacology. vol 36. issue 10. 1998-01-22. PMID:9423928. |
in vivo microdialysis study of gaba(a) and gaba(b) receptors modulating the glutamate receptor/no/cyclic gmp pathway in the rat hippocampus. |
1998-01-22 |
2023-08-12 |
rat |
| E Fedele, G Varnier, M Raiter. In vivo microdialysis study of GABA(A) and GABA(B) receptors modulating the glutamate receptor/NO/cyclic GMP pathway in the rat hippocampus. Neuropharmacology. vol 36. issue 10. 1998-01-22. PMID:9423928. |
to conclude: (a) extracellular hippocampal cgmp is controlled by inhibitory gaba(a) and gaba(b) receptors tonically activated through gabaergic interneurons receiving ampa/kainate-mediated glutamatergic inputs; (b) the gabaergic receptors are not endogenously saturated and can be further stimulated by exogenous agonists; (c) blockade of the gaba-mediated inhibition causes increase of cgmp and epileptic-like behaviour, due largely to endogenous activation of nmda receptors; (d) reproducible cgmp responses to ampa can be observed when the inhibitory gabaergic inputs to the no/guanylyl cyclase system are blocked, confirming the previously proposed existence of ampa/kainate receptors able to increase the nucleotide synthesis. |
1998-01-22 |
2023-08-12 |
rat |
| J H Ye, P L Liu, W H Wu, J J McArdl. Cocaine depresses GABAA current of hippocampal neurons. Brain research. vol 770. issue 1-2. 1998-01-21. PMID:9372216. |
to examine this possibility, the effects of cocaine on the whole cell gaba current (igaba) of freshly isolated rat hippocampal neurons were investigated with the patch-clamp technique. |
1998-01-21 |
2023-08-12 |
rat |
| H Katsumori, Y Minabe, M Osawa, C R Ashb. Acute effects of various GABA receptor agonists and glutamate antagonists on focal hippocampal seizures in freely moving rats elicited by low-frequency stimulation. Synapse (New York, N.Y.). vol 28. issue 1. 1998-01-20. PMID:9414023. |
acute effects of various gaba receptor agonists and glutamate antagonists on focal hippocampal seizures in freely moving rats elicited by low-frequency stimulation. |
1998-01-20 |
2023-08-12 |
rat |
| H Katsumori, Y Minabe, M Osawa, C R Ashb. Acute effects of various GABA receptor agonists and glutamate antagonists on focal hippocampal seizures in freely moving rats elicited by low-frequency stimulation. Synapse (New York, N.Y.). vol 28. issue 1. 1998-01-20. PMID:9414023. |
in this study, we examined the acute anticonvulsant spectrum of (1) dizocilpine (0.03-3 mg/kg), cgs 19755 (1-10 mg/kg), and 7-chlorokynurenic acid (1-100 nmol) (nmda receptor/ionophore complex antagonists); (2) muscimol (0.1-10 nmol; direct gaba(a) agonist); (3) ym90k (3-10 mg/kg; ampa receptor antagonist); and (4) diazepam (2 and 5 mg/kg) and carbamazepine (5 and 20 mg/kg), two standard anticonvulsants, using the partially-kindled hippocampal model for epileptic seizures in freely moving rats. |
1998-01-20 |
2023-08-12 |
rat |
| H L Rowley, C A Marsden, K F Marti. Generalised seizure-induced changes in rat hippocampal glutamate but not GABA release are potentiated by repeated seizures. Neuroscience letters. vol 234. issue 2-3. 1998-01-15. PMID:9364518. |
generalised seizure-induced changes in rat hippocampal glutamate but not gaba release are potentiated by repeated seizures. |
1998-01-15 |
2023-08-12 |
rat |
| H L Rowley, C A Marsden, K F Marti. Generalised seizure-induced changes in rat hippocampal glutamate but not GABA release are potentiated by repeated seizures. Neuroscience letters. vol 234. issue 2-3. 1998-01-15. PMID:9364518. |
the effects of repeated or a single generalised seizure on extracellular glutamate and gamma-aminobutyric acid (gaba) levels in the ventral hippocampus of the freely-moving rat were studied using maximal electroshock-induced seizures in conjunction with in vivo microdialysis. |
1998-01-15 |
2023-08-12 |
rat |
| I Smolders, G M Khan, H Lindekens, S Prikken, C A Marvin, J Manil, G Ebinger, Y Michott. Effectiveness of vigabatrin against focally evoked pilocarpine-induced seizures and concomitant changes in extracellular hippocampal and cerebellar glutamate, gamma-aminobutyric acid and dopamine levels, a microdialysis-electrocorticography study in freely moving rats. The Journal of pharmacology and experimental therapeutics. vol 283. issue 3. 1998-01-15. PMID:9399999. |
effectiveness of vigabatrin against focally evoked pilocarpine-induced seizures and concomitant changes in extracellular hippocampal and cerebellar glutamate, gamma-aminobutyric acid and dopamine levels, a microdialysis-electrocorticography study in freely moving rats. |
1998-01-15 |
2023-08-12 |
rat |
| I Smolders, G M Khan, H Lindekens, S Prikken, C A Marvin, J Manil, G Ebinger, Y Michott. Effectiveness of vigabatrin against focally evoked pilocarpine-induced seizures and concomitant changes in extracellular hippocampal and cerebellar glutamate, gamma-aminobutyric acid and dopamine levels, a microdialysis-electrocorticography study in freely moving rats. The Journal of pharmacology and experimental therapeutics. vol 283. issue 3. 1998-01-15. PMID:9399999. |
this study monitored changes in extracellular hippocampal gamma-aminobutyric acid (gaba), glutamate and dopamine levels after systemic (30 mg/kg/day) or local (intrahippocampal or intranigral, 5 mm or 600 microm for 180 min at 2 microl/min) vigabatrin administration, and evaluated the effectiveness of this antiepileptic drug against pilocarpine-induced seizure activity. |
1998-01-15 |
2023-08-12 |
rat |
| I Smolders, G M Khan, H Lindekens, S Prikken, C A Marvin, J Manil, G Ebinger, Y Michott. Effectiveness of vigabatrin against focally evoked pilocarpine-induced seizures and concomitant changes in extracellular hippocampal and cerebellar glutamate, gamma-aminobutyric acid and dopamine levels, a microdialysis-electrocorticography study in freely moving rats. The Journal of pharmacology and experimental therapeutics. vol 283. issue 3. 1998-01-15. PMID:9399999. |
during the intrahippocampal perfusion with 5 mm vigabatrin, extracellular hippocampal gaba levels increased, whereas the extracellular glutamate and dopamine overflow decreased. |
1998-01-15 |
2023-08-12 |
rat |
| M Alkondon, E F Pereira, C T Barbosa, E X Albuquerqu. Neuronal nicotinic acetylcholine receptor activation modulates gamma-aminobutyric acid release from CA1 neurons of rat hippocampal slices. The Journal of pharmacology and experimental therapeutics. vol 283. issue 3. 1998-01-15. PMID:9400016. |
neuronal nicotinic acetylcholine receptor activation modulates gamma-aminobutyric acid release from ca1 neurons of rat hippocampal slices. |
1998-01-15 |
2023-08-12 |
rat |
| M Alkondon, E F Pereira, C T Barbosa, E X Albuquerqu. Neuronal nicotinic acetylcholine receptor activation modulates gamma-aminobutyric acid release from CA1 neurons of rat hippocampal slices. The Journal of pharmacology and experimental therapeutics. vol 283. issue 3. 1998-01-15. PMID:9400016. |
in experimental conditions similar to those used to record nicotinic responses from neurons in slice (i. e., in the absence of tetrodotoxin), we observed that nicotinic agonists can also induce the release of gaba from hippocampal neurons in culture. |
1998-01-15 |
2023-08-12 |
rat |
| N G Weiland, C Orikasa, S Hayashi, B S McEwe. Distribution and hormone regulation of estrogen receptor immunoreactive cells in the hippocampus of male and female rats. The Journal of comparative neurology. vol 388. issue 4. 1998-01-14. PMID:9388019. |
the density of dendritic spines and synapses, the number of n-methyl-d-aspartate (nmda) binding sites, the levels of nmda receptor subunit nr1 protein, muscimol binding to the gamma-amino butyric acid (gaba)a receptor, and levels of glutamic acid decarboxylase message in the ca1 region of the hippocampus are altered with estrogen treatment. |
1998-01-14 |
2023-08-12 |
rat |
| M Füzesi, B Rácz, B Eliás, K Halas. Enkephalinergic nerve terminals target inhibitory interneurons in the rat hippocampus. Neuroreport. vol 8. issue 11. 1998-01-08. PMID:9261811. |
using correlated light and electron microscopic preembedding enkephalin immunocytochemistry combined with post-embedding gaba immunogold staining, we found morphological evidence of a direct connection between the enkephalinergic and gabaergic systems in the rat hippocampus. |
1998-01-08 |
2023-08-12 |
rat |
| M M McCarthy, A M Davis, J A Mon. Excitatory neurotransmission and sexual differentiation of the brain. Brain research bulletin. vol 44. issue 4. 1997-12-23. PMID:9370215. |
specifically, the mrna coding for the rate-limiting enzyme in gaba synthesis, glutamic acid decarboxylase (gad), is up to twice as high in some steroid-concentrating regions of the neonatal male brain compared to females, including the arcuate nucleus, dorsomedial nucleus, and the ca1 region of hippocampus. |
1997-12-23 |
2023-08-12 |
Not clear |