| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A R Brooks-Kayal, H Jin, M Price, M A Dichte. Developmental expression of GABA(A) receptor subunit mRNAs in individual hippocampal neurons in vitro and in vivo. Journal of neurochemistry. vol 70. issue 3. 1998-03-12. PMID:9489721. |
we demonstrate that multiple gaba(a) receptor subunits are expressed within individual hippocampal neurons, with most cells simultaneously expressing alpha1, alpha2, alpha5, beta1, and gamma2 mrnas. |
1998-03-12 |
2023-08-12 |
rat |
| A R Brooks-Kayal, H Jin, M Price, M A Dichte. Developmental expression of GABA(A) receptor subunit mRNAs in individual hippocampal neurons in vitro and in vivo. Journal of neurochemistry. vol 70. issue 3. 1998-03-12. PMID:9489721. |
further, relative expression of several gaba(a) receptor subunit mrnas changes significantly in embryonic hippocampal neurons during in vitro development, with the relative abundance (compared with beta-actin) of alpha1, alpha5, and gamma2 mrnas increasing 2.3-, 2.7-, and 3.8-fold, respectively, from days 1 to 14, and beta1 increasing 5-fold from days 1 to 21. |
1998-03-12 |
2023-08-12 |
rat |
| A R Brooks-Kayal, H Jin, M Price, M A Dichte. Developmental expression of GABA(A) receptor subunit mRNAs in individual hippocampal neurons in vitro and in vivo. Journal of neurochemistry. vol 70. issue 3. 1998-03-12. PMID:9489721. |
relative abundances of alpha1, beta1, and gamma2 subunit mrnas in acutely dissociated pnd 5 hippocampal neurons are also significantly greater than in embryonic day 17 neurons on day 1 in vitro and exceed the peak values seen in cultured neurons on days 14-21, suggesting that gaba(a) receptor subunit mrna expression within individual hippocampal neurons follows a similar, if somewhat delayed, developmental pattern in vitro compared with in vivo. |
1998-03-12 |
2023-08-12 |
rat |
| A R Brooks-Kayal, H Jin, M Price, M A Dichte. Developmental expression of GABA(A) receptor subunit mRNAs in individual hippocampal neurons in vitro and in vivo. Journal of neurochemistry. vol 70. issue 3. 1998-03-12. PMID:9489721. |
these findings suggest that embryonic hippocampal neuronal culture provides a useful model in which to study the developmental regulation of gaba(a) receptor expression and that developmental changes in gaba(a) receptor subunit expression may underlie some of the differences in functional properties of gaba(a) receptors in neonatal and mature hippocampal neurons. |
1998-03-12 |
2023-08-12 |
rat |
| D B Matthews, L L Devaud, J M Fritschy, W Sieghart, A L Morro. Differential regulation of GABA(A) receptor gene expression by ethanol in the rat hippocampus versus cerebral cortex. Journal of neurochemistry. vol 70. issue 3. 1998-03-12. PMID:9489737. |
differential regulation of gaba(a) receptor gene expression by ethanol in the rat hippocampus versus cerebral cortex. |
1998-03-12 |
2023-08-12 |
rat |
| D B Matthews, L L Devaud, J M Fritschy, W Sieghart, A L Morro. Differential regulation of GABA(A) receptor gene expression by ethanol in the rat hippocampus versus cerebral cortex. Journal of neurochemistry. vol 70. issue 3. 1998-03-12. PMID:9489737. |
one brain region of interest is the hippocampus because it has recently been shown that a subset of gaba(a) receptors in the hippocampus is responsive to pharmacologically relevant concentrations of ethanol. |
1998-03-12 |
2023-08-12 |
rat |
| D B Matthews, L L Devaud, J M Fritschy, W Sieghart, A L Morro. Differential regulation of GABA(A) receptor gene expression by ethanol in the rat hippocampus versus cerebral cortex. Journal of neurochemistry. vol 70. issue 3. 1998-03-12. PMID:9489737. |
therefore, we directly compared the effects of chronic ethanol consumption on gaba(a) receptor subunit gene expression in the hippocampus and cerebral cortex. |
1998-03-12 |
2023-08-12 |
rat |
| D B Matthews, L L Devaud, J M Fritschy, W Sieghart, A L Morro. Differential regulation of GABA(A) receptor gene expression by ethanol in the rat hippocampus versus cerebral cortex. Journal of neurochemistry. vol 70. issue 3. 1998-03-12. PMID:9489737. |
chronic ethanol consumption produced a significant increase in the level of gaba(a) receptor alpha4 subunit peptide in the hippocampus following 40 days but not 14 days. |
1998-03-12 |
2023-08-12 |
rat |
| D B Matthews, L L Devaud, J M Fritschy, W Sieghart, A L Morro. Differential regulation of GABA(A) receptor gene expression by ethanol in the rat hippocampus versus cerebral cortex. Journal of neurochemistry. vol 70. issue 3. 1998-03-12. PMID:9489737. |
the relative expression of hippocampal gaba(a) receptor alpha1, alpha2, alpha3, beta(2/3), or gamma2 was not altered by either period of chronic ethanol exposure. |
1998-03-12 |
2023-08-12 |
rat |
| D B Matthews, L L Devaud, J M Fritschy, W Sieghart, A L Morro. Differential regulation of GABA(A) receptor gene expression by ethanol in the rat hippocampus versus cerebral cortex. Journal of neurochemistry. vol 70. issue 3. 1998-03-12. PMID:9489737. |
hence, chronic ethanol consumption alters gaba(a) receptor gene expression in the hippocampus but in a different manner from that in either the cerebral cortex or the cerebellum. |
1998-03-12 |
2023-08-12 |
rat |
| T Ichida, K Takeda, S Sasaki, M Nakagawa, T Hashimoto, K Kuriyam. Age-related decrease of gamma-aminobutyric acid (GABA) release in brain of spontaneously hypertensive rats. Life sciences. vol 58. issue 3. 1998-03-12. PMID:9499161. |
the release of [3h]gaba observed under high potassium(30 mm) in eleven-week-old(hypertensive) shr hippocampus and the spontaneous release of [3h]gaba in the same aged shr medulla oblongata were lower than those of age-matched wky. |
1998-03-12 |
2023-08-12 |
rat |
| J F Flood, K Uezu, J E Morle. The cortical neuropeptide, cortistatin-14, impairs post-training memory processing. Brain research. vol 775. issue 1-2. 1998-03-09. PMID:9439854. |
in the hippocampus, cortistatin-14 inhibits pyramidal cell firing and co-exists with gaba. |
1998-03-09 |
2023-08-12 |
mouse |
| L K Friedman, E F Sperber, S L Moshé, M V Bennett, R S Zuki. Developmental regulation of glutamate and GABA(A) receptor gene expression in rat hippocampus following kainate-induced status epilepticus. Developmental neuroscience. vol 19. issue 6. 1998-03-05. PMID:9445090. |
developmental regulation of glutamate and gaba(a) receptor gene expression in rat hippocampus following kainate-induced status epilepticus. |
1998-03-05 |
2023-08-12 |
rat |
| L K Friedman, E F Sperber, S L Moshé, M V Bennett, R S Zuki. Developmental regulation of glutamate and GABA(A) receptor gene expression in rat hippocampus following kainate-induced status epilepticus. Developmental neuroscience. vol 19. issue 6. 1998-03-05. PMID:9445090. |
in rat pups resistant to kainate seizure-induced hippocampal neurodegeneration by silver impregnation, glutamate or gaba(a) alpha1-receptor mrnas were unaltered in ca3 neurons 24 h after status epilepticus. |
1998-03-05 |
2023-08-12 |
rat |
| T Falkenberg, N Lindefors, W T O'Connor, O Zachrisson, F Camilli, U Ungersted. GABA release and GAD67 mRNA expression in rat hippocampus following entorhinal cortex activation. Brain research. Molecular brain research. vol 48. issue 2. 1998-02-17. PMID:9332739. |
gaba release and gad67 mrna expression in rat hippocampus following entorhinal cortex activation. |
1998-02-17 |
2023-08-12 |
rat |
| M Sieklucka-Dziuba, R Tokarski, L Józwiak, Z Kleinro. Influence of bilateral clamping of carotid arteries on the seizures susceptibility and central action of AOAA in mice. Acta physiologica Hungarica. vol 84. issue 4. 1998-02-02. PMID:9328629. |
in the experiments carried out on albino-swiss mice it was found, that bilateral clamping of carotid arteries (bcca) for 30 min produce the increase of gaba content in hippocampus, striatum and frontal cortex and decrease of the seizures susceptibility to bicuculline, investigated 7 days after surgery. |
1998-02-02 |
2023-08-12 |
mouse |
| A I Breukel, V M Wiegant, F H Lopes da Silva, W E Ghijse. Presynaptic modulation of cholecystokinin release by protein kinase C in the rat hippocampus. Journal of neurochemistry. vol 70. issue 1. 1998-02-02. PMID:9422380. |
beta-pdbu (50-100 nm) also stimulated the 4-ap-evoked ca2+-dependent release of the classic transmitter gaba, which co-localizes with cck-8 in hippocampal interneurons. |
1998-02-02 |
2023-08-12 |
rat |
| A I Breukel, E Besselsen, F H Lopes da Silva, W E Ghijse. Arachidonic acid inhibits uptake of amino acids and potentiates PKC effects on glutamate, but not GABA, exocytosis in isolated hippocampal nerve terminals. Brain research. vol 773. issue 1-2. 1998-01-27. PMID:9409709. |
arachidonic acid inhibits uptake of amino acids and potentiates pkc effects on glutamate, but not gaba, exocytosis in isolated hippocampal nerve terminals. |
1998-01-27 |
2023-08-12 |
rat |
| A I Breukel, E Besselsen, F H Lopes da Silva, W E Ghijse. Arachidonic acid inhibits uptake of amino acids and potentiates PKC effects on glutamate, but not GABA, exocytosis in isolated hippocampal nerve terminals. Brain research. vol 773. issue 1-2. 1998-01-27. PMID:9409709. |
arachidonic acid (aa), the putative retrograde messenger in long-term potentiation, enhanced extracellular aspartate, glutamate, and gaba levels in rat hippocampus synaptosomes. |
1998-01-27 |
2023-08-12 |
rat |
| A I Breukel, E Besselsen, F H Lopes da Silva, W E Ghijse. Arachidonic acid inhibits uptake of amino acids and potentiates PKC effects on glutamate, but not GABA, exocytosis in isolated hippocampal nerve terminals. Brain research. vol 773. issue 1-2. 1998-01-27. PMID:9409709. |
when stimulating hippocampus synaptosomes with 4-aminopyridine, aa (2 microm) potentiated the ca2+-dependent release of glutamate, but not of gaba, synergistically with pkc activation by 4beta-phorbol-12,13-dibutyric acid. |
1998-01-27 |
2023-08-12 |
rat |