All Relations between hippocampus and gaba

Publication Sentence Publish Date Extraction Date Species
Liesl Maria Fernandes E Mendonça, Arun Bhimrao Joshi, Anant Bhandarkar, Shamshad Shaikh, Samantha Fernandes, Himanshu Joshi, Shrinivas Josh. Potential anxiolytic therapeutics from Hybanthus enneaspermus (L.) F. Muell. - mitigate anxiety by plausibly modulating the GABA Neurochemistry international. 2024-07-13. PMID:39002759. monoamines (serotonin, noradrenaline, dopamine), gamma-aminobutyric acid (gaba), and glutamate were quantified in the different regions of rats' brain (cortex, hippocampus, pons, medulla oblongata, cerebellum). 2024-07-13 2024-07-16 rat
Alyssa F Balleste, Akhila Sangadi, David J Titus, Timothy Johnstone, Derk Hogenkamp, Kelvin W Gee, Coleen M Atkin. Enhancing cognitive recovery in chronic traumatic brain injury through simultaneous allosteric modulation of α7 nicotinic acetylcholine and α5 GABA Experimental neurology. 2024-06-28. PMID:38942266. enhancing cognitive recovery in chronic traumatic brain injury through simultaneous allosteric modulation of α7 nicotinic acetylcholine and α5 gaba traumatic brain injury (tbi) leads to changes in the neural circuitry of the hippocampus that result in chronic learning and memory deficits. 2024-06-28 2024-07-01 Not clear
Fatemeh Rahmati-Dehkordi, Hadi Khanifar, Nazanin Najari, Zeinab Tamtaji, Abdolkarim Talebi Taheri, Michael Aschner, Mehdi Shafiee Ardestani, Hamed Mirzaei, Ehsan Dadgostar, Fatemeh Nabavizadeh, Omid Reza Tamtaj. Therapeutic Potential of Fingolimod on Psychological Symptoms and Cognitive Function in Neuropsychiatric and Neurological Disorders. Neurochemical research. 2024-06-25. PMID:38918332. in the hippocampus, fingolimod decreases glutamate levels and increases gaba levels, suggesting a potential role in modulating synaptic transmission and neuronal excitability. 2024-06-25 2024-06-29 Not clear
Yudai Wada, Soichiro Ushio, Yoshihisa Kitamura, Yoshito Zamami, Toshiaki Send. Effect of Lipopolysaccharide on the Duration of Zolpidem-Induced Loss of Righting Reflex in Mice. Acta medica Okayama. vol 78. issue 3. 2024-06-20. PMID:38902210. additionally, the expressions of γ-aminobutyric acid (gaba)a receptor subunit and k+-cl- cotransporter isoform 2 (kcc2) mrna in the hippocampus and frontal cortex were examined in lps-treated mice. 2024-06-20 2024-06-23 mouse
Bárbara Mota, Ana Rita Brás, Leonardo Araújo-Andrade, Ana Silva, Pedro A Pereira, M Dulce Madeira, Armando Cardos. High-Caloric Diets in Adolescence Impair Specific GABAergic Subpopulations, Neurogenesis, and Alter Astrocyte Morphology. International journal of molecular sciences. vol 25. issue 10. 2024-05-25. PMID:38791562. we focused on the hippocampus, particularly on the gamma-aminobutyric acid (gaba)ergic system, including the ca 2024-05-25 2024-05-27 rat
Yizhen Zhu, Xue Zhao, Ruojing Liu, Dan Yang, Guo G. Effect of Oxygen-Glucose Deprivation of Microglia-Derived Exosomes on Hippocampal Neurons: A Study on miR-124 and Inflammatory Cytokines. Journal of molecular histology. 2024-04-10. PMID:38598045. the results showed that the contents of glu, tnf-α and il-6 mrna increased in the supernatant of cultured hippocampal neurons, the content of gaba decreased, and the survival rate of neurons decreased. 2024-04-10 2024-04-12 human
Sohrab Anvari, Mohammad Javan, Javad Mirnajafi-Zadeh, Yaghoub Fathollah. Repeated Morphine Exposure Alters Temporoamonic-CA1 Synaptic Plasticity in Male Rat Hippocampus. Neuroscience. 2024-03-21. PMID:38513764. in this study, the electrophysiological and biochemical consequences of repeated exposure to morphine in male rats on glutamatergic synaptic transmission, synaptic plasticity, the expression of gaba receptors and glutamate receptors at the temporoammonic-ca1 synapse along the longitudinal axis of the hippocampus (dorsal, intermediate, ventral, dh, ih, vh, respectively) were investigated. 2024-03-21 2024-03-24 rat
Peng Ren, Jing-Ya Wang, Hong-Lei Chen, Yue Wang, Lin-Yu Cui, Jing-Yao Duan, Wen-Zhi Guo, Yong-Qi Zhao, Yun-Feng L. Activation of σ-1 receptor mitigates estrogen withdrawal-induced anxiety/depressive-like behavior in mice via restoration of GABA/glutamate signaling and neuroplasticity in the hippocampus. Journal of pharmacological sciences. vol 154. issue 4. 2024-03-14. PMID:38485341. in the present study, excitatory/inhibitory signaling in the hippocampus was reflected by gaba and glutamate and their associated excitatory-inhibitory receptor proteins, the hpa axis hormones in the hippocampus were assessed by elisa. 2024-03-14 2024-03-17 mouse
Alexander Beletskiy, Anastasia Zolotar, Polina Fortygina, Ekaterina Chesnokova, Leonid Uroshlev, Pavel Balaban, Peter Koloso. Downregulation of Ribosomal Protein Genes Is Revealed in a Model of Rat Hippocampal Neuronal Culture Activation with GABA(A)R/GlyRa2 Antagonist Picrotoxin. Cells. vol 13. issue 5. 2024-03-13. PMID:38474347. downregulation of ribosomal protein genes is revealed in a model of rat hippocampal neuronal culture activation with gaba(a)r/glyra2 antagonist picrotoxin. 2024-03-13 2024-03-15 rat
Alena O Burnyasheva, Natalia A Stefanova, Nataliya G Kolosova, Darya V Telegin. Changes in the Glutamate/GABA System in the Hippocampus of Rats with Age and during Alzheimer's Disease Signs Development. Biochemistry. Biokhimiia. vol 88. issue 12. 2024-03-10. PMID:38462444. here we analyzed the age-related alterations of the levels of glutamate, gaba, as well as enzymes that synthesize them (glutaminase, glutamine synthetase, gaba-t, and gad67), transporters (glast, glt-1, and gat1), and relevant receptors (glua1, nmdar1, nmda2b, and gabaar1) in the whole hippocampus of the wistar rats and of the senescence-accelerated oxys rats, a model of the most common (> 95%) sporadic ad. 2024-03-10 2024-03-14 rat
Alena O Burnyasheva, Natalia A Stefanova, Nataliya G Kolosova, Darya V Telegin. Changes in the Glutamate/GABA System in the Hippocampus of Rats with Age and during Alzheimer's Disease Signs Development. Biochemistry. Biokhimiia. vol 88. issue 12. 2024-03-10. PMID:38462444. our results suggest that there is a decline in glutamate and gaba signaling with age in hippocampus of the both rat strains. 2024-03-10 2024-03-14 rat
Züleyha Doğanyiğit, Aslı Okan, Seher Yılmaz, A Cihangir Uğuz, Enes Akyü. Gender-related variation expressions of neuroplastin TRAF6, GluA1, GABA(A) receptor, and PMCA in cortex, hippocampus, and brainstem in an experimental epilepsy model. Synapse (New York, N.Y.). vol 78. issue 2. 2024-03-04. PMID:38436644. gender-related variation expressions of neuroplastin traf6, glua1, gaba(a) receptor, and pmca in cortex, hippocampus, and brainstem in an experimental epilepsy model. 2024-03-04 2024-03-06 rat
Züleyha Doğanyiğit, Aslı Okan, Seher Yılmaz, A Cihangir Uğuz, Enes Akyü. Gender-related variation expressions of neuroplastin TRAF6, GluA1, GABA(A) receptor, and PMCA in cortex, hippocampus, and brainstem in an experimental epilepsy model. Synapse (New York, N.Y.). vol 78. issue 2. 2024-03-04. PMID:38436644. it was observed that neuroplastin and related proteins tnf receptor-associated factor 6 (traf6), gamma amino butyric acid type a receptors [(gaba(a)], and plasma membrane ca2+ atpase (pmca) protein immunoreactivity levels increased especially in the male hippocampus, and only ampa receptor subunit type 1 (glua1) immunoreactivity decreased, unlike other proteins. 2024-03-04 2024-03-06 rat
Mani Surya Kumar Palepu, Siva Nageswara Rao Gajula, Malleshwari K, Rajesh Sonti, Manoj P Dandeka. SCFAs Supplementation Rescues Anxiety- and Depression-like Phenotypes Generated by Fecal Engraftment of Treatment-Resistant Depression Rats. ACS chemical neuroscience. 2024-02-21. PMID:38382546. administration of scfas (acetate, propionate, and butyrate at 67.5, 25, and 40 mm, respectively) for 7 days exerted robust antidepressant and antianxiety effects by restoring the levels of scfas in plasma and fecal samples, and proinflammatory cytokines (tnf-α and il-6), serotonin, gaba, norepinephrine, and dopamine in the hippocampus and/or frontal cortex of trd and trd-fmt animals. 2024-02-21 2024-02-24 rat
Jennifer A Cale, Ethan J Chauhan, Joshua J Cleaver, Anthoio R Fusciardi, Sophie McCann, Hannah C Waters, Juš Žavbi, Madeleine V Kin. GABAergic and inflammatory changes in the frontal cortex following neonatal PCP plus isolation rearing, as a dual-hit neurodevelopmental model for schizophrenia. Molecular neurobiology. 2024-02-16. PMID:38363536. we recently showed that male lister-hooded rats exposed to pcp-iso exhibit reduced hippocampal expression of the gaba interneuron marker calbindin. 2024-02-16 2024-02-18 rat
Jennifer A Cale, Ethan J Chauhan, Joshua J Cleaver, Anthoio R Fusciardi, Sophie McCann, Hannah C Waters, Juš Žavbi, Madeleine V Kin. GABAergic and inflammatory changes in the frontal cortex following neonatal PCP plus isolation rearing, as a dual-hit neurodevelopmental model for schizophrenia. Molecular neurobiology. 2024-02-16. PMID:38363536. the current study expanded on this by investigating changes to additional populations of gabaergic interneurons in frontal cortical and hippocampal tissue from the same animals (by immunohistochemistry) as well as levels of gaba itself (via elisa). 2024-02-16 2024-02-18 rat
Kavitha Ukkirapandian, Kayalvizhi Elumalai, Karthika Priyadharshini Udaykumar, Sundaravadivel Vp, Muthulakshmi Rangasm. Behavioral and Biochemical Assays for Autism Models of Wistar Rats. Cureus. vol 16. issue 1. 2024-02-13. PMID:38344592. the estimation of antioxidant profile (malondialdehyde {mda}, glutathione {gsh}, catalase (cat), and superoxide dismutase {sod}), proinflammatory markers (tumor necrosis factor {tnf} alpha, transforming growth factor {tgf} beta, interleukin {il} 6, and il-1 beta), neurotransmitters (gamma-aminobutyric acid {gaba} and serotonin), and brain-derived neurotrophic factor (bdnf) in the hippocampal region was done. 2024-02-13 2024-02-15 rat
Navneet Dhaliwal, Jatinder Dhaliwal, Kanwaljit Chopr. 7, 8-dihydroxyflavone Ameliorates Cholinergic Dysfunction, Inflammation, Oxidative Stress, and Apoptosis in a Rat Model of Vascular Dementia. Neurochemical research. 2024-02-01. PMID:38300457. p-akt, p-creb, bdnf, and neurotransmitter (nt) (glu, gaba, and ach) levels were also analyzed in the hippocampus of 2-vo rats. our results show that 7,8-dhf effectively improved memory performance and cholinergic dysfunction in 2-vo model rats. 2024-02-01 2024-02-03 rat
Takashi Iwai, Rei Mishima, Shigeto Hirayama, Honoka Nakajima, Misa Oyama, Shun Watanabe, Hideaki Fujii, Mitsuo Tanab. SYK-623, a δ Opioid Receptor Inverse Agonist, Mitigates Chronic Stress-Induced Behavioral Abnormalities and Disrupted Neurogenesis. Journal of clinical medicine. vol 13. issue 2. 2024-01-26. PMID:38276114. in addition, the number of parvalbumin-positive gaba neurons, which play a crucial role in neurogenesis, was reduced in the hippocampus, and western blot analysis showed decreased glutamic acid decarboxylase protein levels. 2024-01-26 2024-01-28 mouse
Chao Zhang, Kaihua Zhang, Xin Hu, Xianyun Cai, Yufan Chen, Fei Gao, Guangbin Wan. Regional GABA levels modulate abnormal resting-state network functional connectivity and cognitive impairment in multiple sclerosis. Cerebral cortex (New York, N.Y. : 1991). 2024-01-25. PMID:38271282. for this purpose, we used a combination of magnetic resonance spectroscopy and resting-state functional magnetic resonance imaging to study gamma-aminobutyric acid and glutamate concentrations in the posterior cingulate cortex, medial prefrontal cortex and left hippocampus, and inter-network functional connectivity in 29 relapsing-remitting multiple sclerosis patients and 34 matched healthy controls. 2024-01-25 2024-01-28 Not clear