| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joanne C Damborsky, Jerrel L Yake. Regulation of Hippocamposeptal Synaptic Transmission by GABA Journal of molecular neuroscience : MN. vol 74. issue 3. 2024-08-30. PMID:39212758. |
regulation of hippocamposeptal synaptic transmission by gaba hippocamposeptal (hs) neurons send gabaergic projections from the hippocampus to the medial septum/diagonal band of broca (ms/dbb) as part of a reciprocal loop that is critical for memory. |
2024-08-30 |
2024-09-04 |
mouse |
| Mani Surya Kumar Palepu, Harshada Anil Bhalerao, Rajesh Sonti, Manoj P Dandeka. Faecalibacterium prausnitzii, FOS and GOS Loaded Synbiotic Reverses Treatment-resistant Depression in rats: Restoration of Gut-Brain Crosstalk. European journal of pharmacology. 2024-08-30. PMID:39214274. |
it normalized the altered levels of key neurotransmitters such as serotonin, gamma-aminobutyric acid, noradrenaline, and dopamine in the hippocampus and/or frontal cortex. |
2024-08-30 |
2024-09-04 |
rat |
| Hugo R Arias, Paulina Kazmierska-Grebowska, Tomasz Kowalczyk, Yaeun Shim, Bartosz Caban, Chloé Aman, Anne-Emilie Allain, Philippe De Deurwaerdère, Abdeslam Chagraou. Coronaridine congeners induce anticonvulsant activity in rodents by hippocampal mechanisms involving mainly potentiation of GABA European journal of pharmacology. 2024-08-23. PMID:39179091. |
coronaridine congeners induce anticonvulsant activity in rodents by hippocampal mechanisms involving mainly potentiation of gaba the coronaridine congeners catharanthine and 18-methoxycoronaridine (18-mc) display sedative, anxiolytic, and antidepressant properties by acting on mechanisms involving gabaergic and/or monoaminergic transmissions. |
2024-08-23 |
2024-08-27 |
mouse |
| Hugo R Arias, Paulina Kazmierska-Grebowska, Tomasz Kowalczyk, Yaeun Shim, Bartosz Caban, Chloé Aman, Anne-Emilie Allain, Philippe De Deurwaerdère, Abdeslam Chagraou. Coronaridine congeners induce anticonvulsant activity in rodents by hippocampal mechanisms involving mainly potentiation of GABA European journal of pharmacology. 2024-08-23. PMID:39179091. |
a key aspect of this study is that the activity of both congeners was observed only in the presence of gaba, supporting the notion that hippocampal gaba |
2024-08-23 |
2024-08-27 |
mouse |
| Fei Fei, Ziwei Chen, Yi Tao, Xinliang Jiang, Xinyue Xu, Yifeng Ma, Peishi Feng, Ping Wan. Comparison of CUMS at different pregnancy stages, maternal separation, and their effects on offspring in postpartum depression mouse models. Heliyon. vol 10. issue 15. 2024-08-21. PMID:39166014. |
the models were deemed effective based on observed behavioral abnormalities, impaired hippocampal neuron functioning, and reduced serum concentrations of neurotransmitters (5-ht, gaba, and ne). |
2024-08-21 |
2024-08-23 |
mouse |
| Yue Chen, Yiyun Liu, Juncai Pu, Siwen Gui, Dongfang Wang, Xiaogang Zhong, Wei Tao, Xiaopeng Chen, Weiyi Chen, Xiang Chen, Renjie Qiao, Zhuocan Li, Xiangkun Tao, Peng Xi. Treatment response of venlafaxine induced alterations of gut microbiota and metabolites in a mouse model of depression. Metabolic brain disease. 2024-08-16. PMID:39150654. |
in hippocampus, the concentrations of tryptophan, phenylalanine, gamma-aminobutyric acid, glutamic acid, and glutamine were increased, while the level of succinic acid was decreased in the responders group, compared with the non-responders group. |
2024-08-16 |
2024-08-18 |
mouse |
| Dahye Yoon, Seon Min Oh, Hyeon Seon Na, Bo-Ram Choi, Kwan-Woo Kim, Young-Seob Lee, Dong-Ryung Lee, Dae Young Le. Metabolomics study to reveal cognitive improvement with treatment of Scrophularia buergeriana. Scientific reports. vol 14. issue 1. 2024-07-23. PMID:39043762. |
niacinamide, tyrosine, uridine, and valine in the cortex and gaba, choline, creatine, formate, fumarate, hypoxanthine, leucine, myo-inositol, pyroglutamate, and taurine in the hippocampus were identified as biomarker candidates for recovering cognitive impairment. |
2024-07-23 |
2024-07-26 |
mouse |
| Jeferson Jantsch, Fernanda da Silva Rodrigues, Victor Silva Dias, Gabriel de Farias Fraga, Sarah Eller, Márcia Giovenardi, Renata Padilha Guede. Calorie Restriction Attenuates Memory Impairment and Reduces Neuroinflammation in Obese Aged Rats. Molecular neurobiology. 2024-07-22. PMID:39037530. |
we found that cr increases gaba levels in the hippocampus of aged animals, as demonstrated by liquid chromatography coupled with mass spectrometry analysis. |
2024-07-22 |
2024-07-24 |
rat |
| Liesl Maria Fernandes E Mendonça, Arun Bhimrao Joshi, Anant Bhandarkar, Shamshad Shaikh, Samantha Fernandes, Himanshu Joshi, Shrinivas Josh. Potential anxiolytic therapeutics from Hybanthus enneaspermus (L.) F. Muell. - mitigate anxiety by plausibly modulating the GABA Neurochemistry international. 2024-07-13. PMID:39002759. |
monoamines (serotonin, noradrenaline, dopamine), gamma-aminobutyric acid (gaba), and glutamate were quantified in the different regions of rats' brain (cortex, hippocampus, pons, medulla oblongata, cerebellum). |
2024-07-13 |
2024-07-16 |
rat |
| Alyssa F Balleste, Akhila Sangadi, David J Titus, Timothy Johnstone, Derk Hogenkamp, Kelvin W Gee, Coleen M Atkin. Enhancing cognitive recovery in chronic traumatic brain injury through simultaneous allosteric modulation of α7 nicotinic acetylcholine and α5 GABA Experimental neurology. 2024-06-28. PMID:38942266. |
enhancing cognitive recovery in chronic traumatic brain injury through simultaneous allosteric modulation of α7 nicotinic acetylcholine and α5 gaba traumatic brain injury (tbi) leads to changes in the neural circuitry of the hippocampus that result in chronic learning and memory deficits. |
2024-06-28 |
2024-07-01 |
Not clear |
| Fatemeh Rahmati-Dehkordi, Hadi Khanifar, Nazanin Najari, Zeinab Tamtaji, Abdolkarim Talebi Taheri, Michael Aschner, Mehdi Shafiee Ardestani, Hamed Mirzaei, Ehsan Dadgostar, Fatemeh Nabavizadeh, Omid Reza Tamtaj. Therapeutic Potential of Fingolimod on Psychological Symptoms and Cognitive Function in Neuropsychiatric and Neurological Disorders. Neurochemical research. 2024-06-25. PMID:38918332. |
in the hippocampus, fingolimod decreases glutamate levels and increases gaba levels, suggesting a potential role in modulating synaptic transmission and neuronal excitability. |
2024-06-25 |
2024-06-29 |
Not clear |
| Yudai Wada, Soichiro Ushio, Yoshihisa Kitamura, Yoshito Zamami, Toshiaki Send. Effect of Lipopolysaccharide on the Duration of Zolpidem-Induced Loss of Righting Reflex in Mice. Acta medica Okayama. vol 78. issue 3. 2024-06-20. PMID:38902210. |
additionally, the expressions of γ-aminobutyric acid (gaba)a receptor subunit and k+-cl- cotransporter isoform 2 (kcc2) mrna in the hippocampus and frontal cortex were examined in lps-treated mice. |
2024-06-20 |
2024-06-23 |
mouse |
| Bárbara Mota, Ana Rita Brás, Leonardo Araújo-Andrade, Ana Silva, Pedro A Pereira, M Dulce Madeira, Armando Cardos. High-Caloric Diets in Adolescence Impair Specific GABAergic Subpopulations, Neurogenesis, and Alter Astrocyte Morphology. International journal of molecular sciences. vol 25. issue 10. 2024-05-25. PMID:38791562. |
we focused on the hippocampus, particularly on the gamma-aminobutyric acid (gaba)ergic system, including the ca |
2024-05-25 |
2024-05-27 |
rat |
| Yizhen Zhu, Xue Zhao, Ruojing Liu, Dan Yang, Guo G. Effect of Oxygen-Glucose Deprivation of Microglia-Derived Exosomes on Hippocampal Neurons: A Study on miR-124 and Inflammatory Cytokines. Journal of molecular histology. 2024-04-10. PMID:38598045. |
the results showed that the contents of glu, tnf-α and il-6 mrna increased in the supernatant of cultured hippocampal neurons, the content of gaba decreased, and the survival rate of neurons decreased. |
2024-04-10 |
2024-04-12 |
human |
| Sohrab Anvari, Mohammad Javan, Javad Mirnajafi-Zadeh, Yaghoub Fathollah. Repeated Morphine Exposure Alters Temporoamonic-CA1 Synaptic Plasticity in Male Rat Hippocampus. Neuroscience. 2024-03-21. PMID:38513764. |
in this study, the electrophysiological and biochemical consequences of repeated exposure to morphine in male rats on glutamatergic synaptic transmission, synaptic plasticity, the expression of gaba receptors and glutamate receptors at the temporoammonic-ca1 synapse along the longitudinal axis of the hippocampus (dorsal, intermediate, ventral, dh, ih, vh, respectively) were investigated. |
2024-03-21 |
2024-03-24 |
rat |
| Peng Ren, Jing-Ya Wang, Hong-Lei Chen, Yue Wang, Lin-Yu Cui, Jing-Yao Duan, Wen-Zhi Guo, Yong-Qi Zhao, Yun-Feng L. Activation of σ-1 receptor mitigates estrogen withdrawal-induced anxiety/depressive-like behavior in mice via restoration of GABA/glutamate signaling and neuroplasticity in the hippocampus. Journal of pharmacological sciences. vol 154. issue 4. 2024-03-14. PMID:38485341. |
in the present study, excitatory/inhibitory signaling in the hippocampus was reflected by gaba and glutamate and their associated excitatory-inhibitory receptor proteins, the hpa axis hormones in the hippocampus were assessed by elisa. |
2024-03-14 |
2024-03-17 |
mouse |
| Alexander Beletskiy, Anastasia Zolotar, Polina Fortygina, Ekaterina Chesnokova, Leonid Uroshlev, Pavel Balaban, Peter Koloso. Downregulation of Ribosomal Protein Genes Is Revealed in a Model of Rat Hippocampal Neuronal Culture Activation with GABA(A)R/GlyRa2 Antagonist Picrotoxin. Cells. vol 13. issue 5. 2024-03-13. PMID:38474347. |
downregulation of ribosomal protein genes is revealed in a model of rat hippocampal neuronal culture activation with gaba(a)r/glyra2 antagonist picrotoxin. |
2024-03-13 |
2024-03-15 |
rat |
| Alena O Burnyasheva, Natalia A Stefanova, Nataliya G Kolosova, Darya V Telegin. Changes in the Glutamate/GABA System in the Hippocampus of Rats with Age and during Alzheimer's Disease Signs Development. Biochemistry. Biokhimiia. vol 88. issue 12. 2024-03-10. PMID:38462444. |
here we analyzed the age-related alterations of the levels of glutamate, gaba, as well as enzymes that synthesize them (glutaminase, glutamine synthetase, gaba-t, and gad67), transporters (glast, glt-1, and gat1), and relevant receptors (glua1, nmdar1, nmda2b, and gabaar1) in the whole hippocampus of the wistar rats and of the senescence-accelerated oxys rats, a model of the most common (> 95%) sporadic ad. |
2024-03-10 |
2024-03-14 |
rat |
| Alena O Burnyasheva, Natalia A Stefanova, Nataliya G Kolosova, Darya V Telegin. Changes in the Glutamate/GABA System in the Hippocampus of Rats with Age and during Alzheimer's Disease Signs Development. Biochemistry. Biokhimiia. vol 88. issue 12. 2024-03-10. PMID:38462444. |
our results suggest that there is a decline in glutamate and gaba signaling with age in hippocampus of the both rat strains. |
2024-03-10 |
2024-03-14 |
rat |
| Züleyha Doğanyiğit, Aslı Okan, Seher Yılmaz, A Cihangir Uğuz, Enes Akyü. Gender-related variation expressions of neuroplastin TRAF6, GluA1, GABA(A) receptor, and PMCA in cortex, hippocampus, and brainstem in an experimental epilepsy model. Synapse (New York, N.Y.). vol 78. issue 2. 2024-03-04. PMID:38436644. |
gender-related variation expressions of neuroplastin traf6, glua1, gaba(a) receptor, and pmca in cortex, hippocampus, and brainstem in an experimental epilepsy model. |
2024-03-04 |
2024-03-06 |
rat |